Gene NME4 (Human)

NME4

Species: Human
Alias: NME4
External Links:
Annotation:

Classification

Group: NDK
Family: NDK

Sequence

Name Sequence Type Origin Length Description Download
NME4.AA Protein None 187 None Fasta, JSON
NME4.NA RNA None 1059 None Fasta, JSON
NME4.kin_dom Protein Kinase Domain None 134 None Fasta, JSON

Protein domain

Protein domains of NME4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NDK NME4.AA NDK 38-172 54 1.9e-86 298.27 Pfam 1-140 (140) Show / Hide 
Range on Protein: 38-172
Range on HMM: 1-140/140
Sequence Identity: 54% (76 aa)

ERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHTDSAEA--APG
|||.. .|||.|||.|.|..|.||||.||..|.|||... .  . |||.... |||.| |. .|.||||||||||| |...  |.|.| |. |||  |||
ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKGKPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAKEAPG

TIRGDFSVHI--SR-NVIHASDSVEGAQREIQLWFQSSEL
||||||.|.|  .| ||.|.|||.| |.||| .||  .|.
TIRGDFAVSIYPGRRNVVHGSDSPESAEREIAFWFPPEEI
NDK NME4.AA NDK 37-174 52 1.1e-85 291.86 SMART 1-142 (142) Show / Hide 
Range on Protein: 37-174
Range on HMM: 1-142/142
Sequence Identity: 52% (74 aa)

RERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQ-DLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHTD---SAEA
 |||....|||.|||.|.|..|.||||.||..|.|||.|...  ..|||. ... |||.. |. .|.||||||||||| |... .| |.| |.    .||
MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA

APGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVS
|||||||||...| ||..|.|||.| |.|||..||..||...
APGTIRGDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE