Gene NME3 (Human)

NME3

Species: Human
Alias: NME3
External Links:
Annotation:

Classification

Group: NDK
Family: NDK

Sequence

Name Sequence Type Origin Length Description Download
NME3.AA Protein None 169 None Fasta, JSON
NME3.NA RNA None 1038 None Fasta, JSON
NME3.kin_dom Protein Kinase Domain None 134 None Fasta, JSON

Protein domain

Protein domains of NME3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NDK NME3.AA NDK 22-156 56 1.4e-94 325.32 Pfam 1-140 (140) Show / Hide 
Range on Protein: 22-156
Range on HMM: 1-140/140
Sequence Identity: 56% (79 aa)

ERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADA--PPG
||||. .|||.|||.|.|||..||||||||.||.|......|...|||||....||.. ||..| |||||||||.| ..... |...||||||.|  .||
ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKGKPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAKEAPG

TIRGDFCIEV--GK-NLIHGSDSVESARREIALWFRADEL
||||||....  |. |..|||||.||| ||||.||...|.
TIRGDFAVSIYPGRRNVVHGSDSPESAEREIAFWFPPEEI
NDK NME3.AA NDK 21-158 55 6.4e-92 312.61 SMART 1-142 (142) Show / Hide 
Range on Protein: 21-158
Range on HMM: 1-142/142
Sequence Identity: 55% (79 aa)

HERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYA-ELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATN---PADA
 |||| ..|||.|||.|.|||..||||||||.||.|..|...|...|||| |....||. .||..|.|||||||||.| ....|.| ..|.||   |..|
MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA

PPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLC
 ||||||||....|.| .|||||.||| ||||.||  .|.. 
APGTIRGDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE