AqueK688

Species: A.queenslandica
Alias: AqueK688
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK688.AA Protein None 610 None Fasta, JSON
AqueK688.kin_dom Protein Kinase Domain None 89 None Fasta, JSON

Protein domain

Protein domains of AqueK688.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK688.AA Kelch_2 11-67 19 6.8e-05 22.72 Pfam 1-51 (51) Show / Hide
Range on Protein: 11-67
Range on HMM: 1-51/51
Sequence Identity: 19% (11 aa)

KRSNHSTVRVGDYLYMWGGLQSDLPKVHNNDKKKALSSLMEVYHLPTGRWEQKPTTG
 |..|... .|. .|..||.        ... .   |. . .... | ||.  |  .
PRYCHASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP

Kelch_1 AqueK688.AA Kelch_1 11-67 17 0.000493 18.23 Pfam 1-45 (45) Show / Hide
Range on Protein: 11-67
Range on HMM: 1-45/45
Sequence Identity: 17% (10 aa)

KRSNHSTVRVGDYLYMWGGLQSDLPKVHNNDKKKALSSLMEVYHLPTGRWEQKPTTG
.|..|. . .....|  ||  .              ..  |.|.. |..|.. |. .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP

Kelch_1 AqueK688.AA Kelch_1 72-119 18 3e-06 26.09 Pfam 1-45 (45) Show / Hide
Range on Protein: 72-119
Range on HMM: 1-45/45
Sequence Identity: 18% (9 aa)

GIFAYASAAIGNEIFYFGGRCNHDSCYHNSLYSFNVDTFTWRELSPTT
    .........|. .||...    | || ......| .|....| .
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP

Kelch_2 AqueK688.AA Kelch_2 72-119 19 0.016686 13.64 Pfam 1-51 (51) Show / Hide
Range on Protein: 72-119
Range on HMM: 1-51/51
Sequence Identity: 19% (10 aa)

GIFAYASAAIGNEIFYFGGR---CNHDSCYHNSLYSFNVDTFTWRELSPTT
. .  ||. .|. |. |||.     ...|...... .. .| .|.....  
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP

Kelch_2 AqueK688.AA Kelch_2 254-299 20 2.96885 5.09 Pfam 1-51 (51) Show / Hide
Range on Protein: 254-299
Range on HMM: 1-51/51
Sequence Identity: 20% (11 aa)

ERWDHSSVFINSNLGPHLLVVGGL---------FKNDCWLLDINKRIWKQLLNVS
 |  |.|. .    |  ..|.||.         . .| |..| ... |. .  . 
PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP

Kinase AqueK688.AA Dicty4 507-585 41 3.3e-18 57.5 In-house 1-85 (277) Show / Hide
Range on Protein: 507-585
Range on HMM: 1-85/277
Sequence Identity: 41% (36 aa)

ITMTRRVLGRGGWGEVRVASFHGLEVAAKVL--HDTIISEYNLSLFSREMNIASKIRHPNLLQFMGATT-----EGNPIILTELMP
|. . | .|.|. |||  ..  | ||| |.|  | .  .|. |. | .| .| .||||||...|||| |      | . | ||.||
INIEQR-IGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMP

Kinase AqueK688.AA TKL 514-585 19 7.4e-15 49.94 In-house 1-121 (364) Show / Hide
Range on Protein: 514-585
Range on HMM: 1-121/364
Sequence Identity: 19% (24 aa)

LGRGGWGEVRVASFHG----------LEVAAKVLHDTIISEYNL-------------------------SLFSREMNIASKIRHPNLLQFMGATTEGN--
.|.|| |||  . ..|           .|| |... .  .| ..                           . .|... |..||||..||||. ....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PIILTELMP
            . | .|..|
CVCMHPVGPWGQLCIVMEYCP

Kinase AqueK688.AA DRK 507-585 39 1.9e-14 45.4 In-house 1-80 (258) Show / Hide
Range on Protein: 507-585
Range on HMM: 1-80/258
Sequence Identity: 39% (32 aa)

ITMTRRVLGRGGWGEVRVASFHGLEVAAKVLHDTIIS-EYNLSLFSREMNIASKIRHPNLLQFMGATTE-GNPIILTELMP
|    |. |||..|||   .  | .|| | |    |  |  |. | || |. .. ||||  ||||. ..   . | .| ||
IKIGNRI-GRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMP

Kinase AqueK688.AA Shk 507-585 43 4.9e-14 46.93 In-house 1-80 (269) Show / Hide
Range on Protein: 507-585
Range on HMM: 1-80/269
Sequence Identity: 43% (35 aa)

ITMTRRVLGRGGWGEVRVASFHGLEVAAKVLHDTIISEYNLSLFSREMNIASKIRHPNLLQFMGATT--EGNPIILTELMP
|. .   || |  | |  .   | ||| ||.| .  .|. .. |  |  | |||.|||.. |||| |   |   | |||||
INRE-DFLGQGSFGKVYKGRCRGKEVAVKVMHKQNFDENTMTSFRKEVHIMSKIFHPNICLFMGACTSQPGKCMIVTELMP

Kinase AqueK688.AA LISK 513-571 28 5e-13 38.47 In-house 1-64 (296) Show / Hide
Range on Protein: 513-571
Range on HMM: 1-64/296
Sequence Identity: 28% (18 aa)

VLGRGGWGEVRVASFH--GLEVAAKVLH---DTIISEYNLSLFSREMNIASKIRHPNLLQFMGA
..|.|. |.|   .    | ..| | .|   .. . . ..  . ||. .  ..|||| .||||.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV

Kinase AqueK688.AA CZAK 512-584 33 3.7e-10 33.26 In-house 5-84 (279) Show / Hide
Range on Protein: 512-584
Range on HMM: 5-84/279
Sequence Identity: 33% (27 aa)

RVLGRGGWGEVRVASFHGLEVAAKVLHD----TIISEYNLSLFSREMNIASKIRHPNLLQFMGATTEGN---PIILTELM
.. |.|  |||. |   |  || | .|     .  .   .  | .|  | || .||| .||.|| .|..     | .| |
QTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWM

Kinase AqueK688.AA TKL-Unique 510-582 28 1.2e-09 30.43 In-house 1-80 (290) Show / Hide
Range on Protein: 510-582
Range on HMM: 1-80/290
Sequence Identity: 28% (23 aa)

TRRVLGRGGWGEVRVASFHGLEVAAKVLH-DTIISEYNLSLFSREMNIASKIR-HPNLLQFMGATT-----EGNPIILTE
   ..|.|| |.|  . ..| .|| |..|    .|   .  |..| |. .|.. |||....||...     ..| .| .|
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVME

Kinase AqueK688.AA Pkinase_Tyr 507-585 28 6e-09 30.93 Pfam 1-90 (270) Show / Hide
Range on Protein: 507-585
Range on HMM: 1-90/270
Sequence Identity: 28% (26 aa)

ITMTRRVLGRGGWGEVRVASFH------GLEVAAKVLHDTIISEY--NLSLFSREMNIASKI-RHPNLLQFMGATT-EGNP---IILTELMP
||.  ..||.|  |||. .  .      ...|| |.| ..  .|     .... |..| ... .|||.....|. | .| |   .| .|.||
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMP

Kinase AqueK688.AA Src 507-584 33 1.1e-08 25.56 In-house 1-76 (255) Show / Hide
Range on Protein: 507-584
Range on HMM: 1-76/255
Sequence Identity: 33% (27 aa)

ITMTRRVLGRGGWGEVRVASFHG-LEVAAKVLHDTIISEYNLSLFSREMNIASKIRHPNLLQFMGATTEGNPI-ILTELM
|.. |. ||.|  |||  . . |  .|| |.|            | .| .|  | ||..|.|     ... || | ||.|
IKLCRK-LGQGQFGEVWMGYWNGNTKVAVKTLKPGT---MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYM

Kinase AqueK688.AA MLK 508-585 19 1.3e-08 26.16 In-house 1-93 (291) Show / Hide
Range on Protein: 508-585
Range on HMM: 1-93/291
Sequence Identity: 19% (18 aa)

TMTRRVLGRGGWGEVRVASFHGLE-----VAAKVLHDTIISEYNLS-----LFSREMNIASKIRHPN----LLQFMGATTE-GN-PIILTELMP
  . ...| |. |.|  . ... .     || |  . .|. .   .      | .| .......|||      ||.|. .. ..   |..| ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCE

Kinase AqueK688.AA Abl 507-585 34 2.8e-08 23.22 In-house 1-78 (252) Show / Hide
Range on Protein: 507-585
Range on HMM: 1-78/252
Sequence Identity: 34% (28 aa)

ITMTRRVLGRGGWGEVRVASF--HGLEVAAKVLHDTIISEYNLSLFSREMNIASKIRHPNLLQFMGATTEGNPI-ILTELMP
|.|  . || | .||| .. .  |.. || | |..  .   ..  | .|  |  ...|||| | .|  |   |  |.|| |.
IMMKHK-LGGGQYGEVYEGVWKRHDCTVAVKTLKEDTM---EVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMC