Gene AqueK671 (A.queenslandica)
AqueK671
Species: A.queenslandica
Alias: AqueK671
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
AqueK671.AA | Protein | None | 689 | None | Fasta, JSON |
AqueK671.kin_dom | Protein Kinase Domain | None | 215 | None | Fasta, JSON |
Protein domains of AqueK671.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | AqueK671.AA | IRAK | 397-627 | 35 | 3e-73 | 249.68 | In-house | 1-236 (317) | Show / Hide |
Range on Protein: 397-627 Range on HMM: 1-236/317 Sequence Identity: 35% (87 aa) FTEGLV-GHGAFGSVFRANIRGCG-PYAIKKLHNRSEMQSEMEGTLFFEPLHQESFML---ELQSLVKYKHRNVLSLIAISDDGPRPCLVYEYMENGSLA | .... | |.|| |.|. ... . .||.|||.. .|. .. | ..| ||... .. | |...| . . ... .||||.|| |||| FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNE---------HWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLE DCLLGKKN-VH---LDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRHLTPKLSDFGLARES---LNRPTHVTTVSANSRVAMGTVAYMA | | . .. . | | |..|.. | ...||| . ..||||.||.||||| |.|||..||||.|.. .. .. |. |.| || .||. DRLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHV-RGTTWYMP PEFLR--NSKPSSKTDVYAFGVVILELFTGQ-AADDPSRDIRTLHD |||.| . . ||||| ||.|.||..||. |..| .. ..| | PEFIRDPQGQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKD |
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Kinase | AqueK671.AA | TKL | 402-613 | 23 | 5.5e-55 | 188.98 | In-house | 1-286 (364) | Show / Hide |
Range on Protein: 402-613 Range on HMM: 1-286/364 Sequence Identity: 23% (68 aa) VGHGAFGSVFRANIRG---------CGPYAIKKLHNRSEMQSEM-------------EGTLFFEPLHQESFMLELQSLVKYK--HRNVLSLIAISDDGPR .| |.|| |.... || . . |.||.. .... ... | . .... | .| . ... . | |........ ..| IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDM-QLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC -------------PCLVYEYMENGSLADCLLGKKNVHLDWKLRLEIASQVADALNFLHRVNE----PQSLIHGDVKSSNILLDRHLT------------- .|.|.||...||| . |. | .|. .| ..| ..|.|| | . .|| | ||.|||.|...| GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW -PKLSDFGLARES----LNRPTHVT--------TVSANSRVAMGTVAYMAPEFLRNS----------------KPSSKTDVYAFGVVILELFTGQ .|..||||.|. . | | . . .. || ..|||| ||.. . | |.|||.||.|. |..|.. CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC |
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Pkinase | AqueK671.AA | Pkinase | 396-613 | 22 | 2.2e-41 | 147.4 | Pfam | 1-209 (293) | Show / Hide |
Range on Protein: 396-613 Range on HMM: 1-209/293 Sequence Identity: 22% (53 aa) IFTEGLVGHGAFGSVFRA-NIRGCGPYAIKKLHNRSEMQSEMEGTLFFEPLHQESFMLELQSLVKYKHRNVLSLIAISDDGPRPCLVYEYMENG----SL . ... .| |.||.|... .. . .|.|.. | . |... |.. |.| . . .| |.. |. . |......| ||.|.| .| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL--------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDL ADCLLGKKNVHL--DWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRHLTP----KLSDFGLARE-SLNRPTHVTTVSANSRVAMGTVAYM .| . .... . ... .. |.. .|...|. . || |.|..|||.|.. .. |..|||||. . . . . || || FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYM APEFLR-NSKPSSKTDVYAFGVVILELFTGQ ||| .| ... ..| |....|... |...|. APEVIRGGQYYGPKVDMWSCGCILYEMLCGR |
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Kinase | AqueK671.AA | TK | 396-611 | 16 | 7.6e-40 | 130.74 | In-house | 1-389 (486) | Show / Hide |
Range on Protein: 396-611 Range on HMM: 1-389/486 Sequence Identity: 16% (66 aa) IFTEGLVGHGAFG---SVFRANIRG--------------------------CGPYAIKKLHNRSEMQSEM----------EGTLFFEPLHQESFMLELQS | . |.|.|| |... || . | |.| |. ..|..|. . .. |. |.. ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDG-GE--------DFLEEAEE LVKYK-----HRNVLSLIAISDDG------------PRPCLVYEYMENGS----LADCLL--GKKNVH-------------------------------- . . . | |...|.... .| . ...| |||..|. | | | .| | MKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESN ----------------------------------------LDWKLRLEIASQVADALNFLHRVN---EPQSLIHGDVKSSNILLDRHLT----------- |. . .| .. |.|... .||. | . | ..|.|. |.|...... SPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPV PKLSDFG--------LARESLNRPTHVTTVSANSRVAMGT--------------------VAYMAPEFLR---------NSKPSSKTDVYAFGVVILELF |..||| |||. .. ... | .. | . .|||| |. . | ..|.||..|||.. |.| CKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIF T | T |
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Kinase | AqueK671.AA | MLK | 396-613 | 27 | 6.1e-38 | 129.24 | In-house | 1-233 (291) | Show / Hide |
Range on Protein: 396-613 Range on HMM: 1-233/291 Sequence Identity: 27% (68 aa) IFTEGLVGHGAFGSVFRANIRGCG----PYAIKKLHNRSEMQSEMEGTLFFEPLHQESFMLELQSLVKYKHRN-----VLSLIAISDDGPRPCLVYEYME | .. .|.|.||.|.... |. |.|. . | . . ... |. | | | . .|.| . . ....... |.| ||.| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYC------EQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCE NGSLADCLLGKKN------------VHLDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDR------HLTPKLSDFGLARESLNRPTHVTT .|||.. | |... . | . . .| |.| ....|| ..|. .|| | ||.|||.|. |.| | .|||..|. ... GGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHS-MAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRD-------WHQ VSANSRVAMGTVAYMAPEFL---RNSKPSSKTDVYAFGVVILELFTGQ .| ..||.|.|||| . |..| | | ||. .|||. |..|.. MCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE |
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Kinase | AqueK671.AA | RIPK | 402-612 | 29 | 3.9e-35 | 117.18 | In-house | 1-224 (290) | Show / Hide |
Range on Protein: 402-612 Range on HMM: 1-224/290 Sequence Identity: 29% (68 aa) VGHGAFGSVFRANIRGCGPYAIKKLHNRSEMQSEMEGTLFFEPLHQESFMLELQSLVKYKHRNVLSLIAISDDG-----PR-PCLVYEYMENGSLADCLL || |.|| ||.| | | ..|| . ... .|. .. | . . | ........ . . . . .| ||||||||.. | VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQE------RMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLH GKKN---VHLDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRHLTPKLSDFGLARESLNRPTHVTT--------VSANSRVAMGTVAYMA | . |.|| . ... . ..|| | | .|| | | .|||.|... |..||||| . .. |... | |. || .||. TKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNPP--IIHRDLKPENILVDNNFHVKIADFGLA--TWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMP PEFLR--NSKP----SSKTDVYAFGVVILELFTG || .| |.|| . | ||| |..|. |..|. PEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQ |
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Kinase | AqueK671.AA | UTK | 403-612 | 26 | 9.6e-35 | 116.29 | In-house | 8-236 (296) | Show / Hide |
Range on Protein: 403-612 Range on HMM: 8-236/296 Sequence Identity: 26% (64 aa) GHGAFGSVFRANIRGCG------PYAIKKLHNRSEMQSEMEGTLFFEPLHQE-SFMLELQ---SLVKYK-HRNVLSLIAISDDGPRPCLVYEYMENGSLA |.|||| |..| . | |.|.. ... | |.|. ||.| . . . . |.||| |... .. ...|.||||||.|. GQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEP---------YPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLR DCLLGKKN------VHLDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRH-------LTPKLSDFG---LARESLNRPTHVTTVSANSRV ..| . ..|. ||. |...|.....||. . ..|.|. |.|...| .. |..||| ..|. .|. . .. ...| SYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCG----FVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRR-VNTFH-FSNRYWESYY AMGT------VAYMAPEFLRNS-KPSSKTDVYAFGVVILELFTG | . .. |||| | . ....|.||..|||| |..|. YMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW |
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Kinase | AqueK671.AA | TK-Unique | 396-611 | 20 | 6.3e-34 | 114.43 | In-house | 1-234 (294) | Show / Hide |
Range on Protein: 396-611 Range on HMM: 1-234/294 Sequence Identity: 20% (52 aa) IFTEGLVGHGAFGSVFRANIRGCG-------PYAIKKLHNRSEMQSEMEGTLFFEPLHQESFMLELQSLVKYK-HRNVLSLIAISDDGP-RPCLVYEYME .. . ..| |||| |.|. ..| |.|.|. .. ..... |. |.| . . . | |..... .. . ......||.. LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQD------------FLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCP NGSLADCLLGKKNVH------------------------LDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRHLTPKLSDFGLARESLNR .|.| ..| .. .. .. |. . .| |.| ....|.. .. .|.|. ..|.|| .... |..|||.||. . CGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQ--RKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT- PTHVTTVSANS-RVAMGTVAYMAPEFLR--NSKP-SSKTDVYAFGVVILELFT ..| ... . . ...|||| |. ..|.||..|||.. |.|| ----NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT |
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Kinase | AqueK671.AA | TKL-Unique | 401-613 | 28 | 7.4e-34 | 116.84 | In-house | 4-225 (290) | Show / Hide |
Range on Protein: 401-613 Range on HMM: 4-225/290 Sequence Identity: 28% (68 aa) LVGHGAFGSVFRANIRGCGPYAIKKLHNRSEMQSEMEGTLFFEPLHQESFMLELQSLVKYK-HRNVLSLIAISD----DGPRPCLVYEYMENGSLADCLL ..| |..|.|... || |.|||..|. .. .||. . | |. . | . | |.. ..... . |. |.| ||.. ||| | | KIGEGGYGQVYKGKWRGY-PVAIKQFHPNEDSSNEMM----------QEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLH G--------KKNVHLDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRH-----LTPKLSDFGLARESLNRPTHVTTVSANSR--VAMGTV ..| |....|. .| ..|.....||. . | ||.| ||||.|.|.. . |..||||.. . .. . .. . ..| . .|. QNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP--IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSF AYMAPEFLRN--SKPSSKTDVYAFGVVILELFTGQ .|||| ||. .. | | |||.||.| |..|.. RWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRK |
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Kinase | AqueK671.AA | Pkinase_Tyr | 403-611 | 27 | 6.7e-33 | 112.04 | Pfam | 8-209 (270) | Show / Hide |
Range on Protein: 403-611 Range on HMM: 8-209/270 Sequence Identity: 27% (61 aa) GHGAFGSVFRANIR-----GCGPYAIKKLHNRSEMQSEMEGTLFFEPLHQESFMLELQSLVKY-KHRNVLSLIAISD--DGP-RPCLVYEYMENGSLADC |.||||.|... . .. | |.|.| . . |... .|.|| |.. . .. .| |...|... ..| ....| |||..|.| | GEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQN---------CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY LLGK--KNVHLDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRHLTPKLSDFGLARESLNRPTHVTTVSANSRVAMGTVAYMAPEFLRNS | . . .|. | |... |.|.....|.. | .|| |. |.|... .. | .|||||| | . .... .... . |||| .... LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN----CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLP---IKWMAPECINYG KPSSKTDVYAFGVVILELFT | ..|.||..|||.. |.|| KFTTKSDVWSFGVLMWEIFT |
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Kinase | AqueK671.AA | S_TKc | 396-675 | 22 | 6.5e-31 | 109.94 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 396-675 Range on HMM: 1-231/231 Sequence Identity: 22% (66 aa) IFTEGLVGHGAFGSVFRANIRG-CGPYAIKKLHNRSEMQSEMEGTLFFEPLHQESFMLELQSLVKYKHRNVLSLIAISDDGPRPCLVYEYMEN--GSLAD ..|.||||.|... .. .|||... |... |.| | | .| |. |. . .| . ..| ||... |.| | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFD CLLGKKNVH----LDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRHLTPKLSDFGLARESLNRPTHVTTVSANSRVAMGTVAYMAPEFL . .. .. .. |...||...|. . || |.| .|||||. . |..||||||. . || ||||| | YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHG----IIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL RNSKPSS-KTDVYAFGVVILELFTGQAADDPSRDIRTLHDSNMKLIFAKIVTIELPPLVFACILLELKLGLRSNGNDAIG---IVLCLFYA . . | |....|... |...|. . .|...| ||. . . | . .|. | .| . | . ---GYGKCKCDWWSCGCILYEMLCGYPPFP-----------QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | AqueK671.AA | LRRK | 396-613 | 24 | 1.2e-27 | 94.91 | In-house | 1-279 (351) | Show / Hide |
Range on Protein: 396-613 Range on HMM: 1-279/351 Sequence Identity: 24% (73 aa) IFTEGLVGHGAFG-SVFRANIRG---------------------------CGPYAIKKLHNRS------------------------EMQSEMEGTLFFE . | ..| |.|| .|.||. || | . ||||.. . | .. ... . . LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR PLHQESFMLELQSLVKYKHRNVLSLIAISDDGPRPCLVYEYMENGSLADCLLGKKNV-------HLDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVK .. .| |. . . .| |..||. .. . |. |.| ||. .|.| . | ||. |..| |.|.|| |.|.....||. | | .|| | | AFR--EFRHEVWIMSHLNHPNIVSLKGFCIH-PL-CMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPP--IIHRDLK SSNILLDRHLTP------------KLSDFGLAR--ESLNRPTHVTTVSANSRVAMGTVAYMAPEFLR---NSKPSSKTDVYAFGVVILELFTGQ | |||| .. .. |..|||. | .. .. . |. .|||| .| .. . |.|.|.||... || |.| SPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFH--------MGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ |
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Kinase | AqueK671.AA | Ciliate-E2-Unclassified | 403-613 | 19 | 1.5e-27 | 92.63 | In-house | 8-267 (352) | Show / Hide |
Range on Protein: 403-613 Range on HMM: 8-267/352 Sequence Identity: 19% (52 aa) GHGAFGSVFRA--NIRGCGPYAIKKLHNRSEMQSEMEGTLFFEPLHQESFMLELQ-------------SLVKYKHRNVLSLIAISDDGPRPCLVYEYMEN |.|.||.|... . . ||.| .. . . . | . .. | ... .|. .| ... .. . | ...|.||.|. GQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEG GSLADCLLGKKN---------------VHLDWKLRL-----EIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRHL---TPKLSDFGLARESLNRPT |.| ... .|. ... . . .. |. ..|..||. | || | | .|||.| .|..|||..... . . GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN---NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNN HVTTV---------SANSRVAMGTVAYM----APEFLRNSKPS----SKTDVYAFGVVILELFTGQ | . .. .|| || ||| |.. ... | |....||.. |. .|. CD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY |
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Kinase | AqueK671.AA | TyrKc | 396-658 | 20 | 1.1e-23 | 85.95 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 396-658 Range on HMM: 1-280/280 Sequence Identity: 20% (63 aa) IFTEGLVGHGAFGSVFRANIRGCGPYAIKKLHNRSEMQSEMEGTLFFEPLHQESFMLELQSLVKY--KHRNVLSLIAISDDG-------PRPCLVYEYME | . |.|||| |... . . |.|.|.. . .| || |.. . |. .| |.. |... .. . ...| |||. ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP NGSLADCLLGKKNVHLDWKLRLEIASQVADALNFLHRVNEPQSLIHGDVKSSNILLDRHLTPKLSDFGLARESLNR----PTHVTTVSANSRVAM--GTV .|.| | | ... | .| |... |.|. ..||. .|| | |.|... .| | |||||.|. . . . ... .. . . HGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI AYMAPEFLRNSKPSSKTDVYAFGVVILELFTG---QAAD-----DPSRDIRTLHDSNMKLIFAKI--------VTIELPPLVFACILL---------ELK |||| .. .| ..|.||..|||.. |.|| . . .... . .. . . . . |. . | |.. RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH LGL . ECF |