Gene AqueK667 (A.queenslandica)
AqueK667
Species: A.queenslandica
Alias: AqueK667
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK667.AA | Protein | None | 951 | None | Fasta, JSON |
| AqueK667.kin_dom | Protein Kinase Domain | None | 94 | None | Fasta, JSON |
Protein domains of AqueK667.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK667.AA | TAK1 | 302-394 | 22 | 1.4e-21 | 69.54 | In-house | 168-284 (284) | Show / Hide |
Range on Protein: 302-394 Range on HMM: 168-284/284 Sequence Identity: 22% (27 aa) RYTAPEV----------------------LRGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDT-ETIFEGLNQMANGRRPPLLVG---HPSFVNELLQ |. |||| .|. | ..| ||. ..|..||...|..| ..... ... . .||.|||.. | .. . RWMAPEVRELFDFKSNRIIINQPTGFQKVFRCEKY-NMKCDIYSWGIIMWEVISRKHP-YDHIMNPNSAYRIMWAIHNGNRPPMETNRSDCPKRIEQFMK KCWNQDPGVRLTSTELVEK .||...| | .. | |. CCWDDNPEKRPSMQECVKY |
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| Kinase | AqueK667.AA | TKL | 302-395 | 27 | 1.3e-20 | 70.98 | In-house | 238-364 (364) | Show / Hide |
Range on Protein: 302-395 Range on HMM: 238-364/364 Sequence Identity: 27% (35 aa) RYTAPEVLRGTSYSTEKR---------------DIFNFAITLWEMLARQEPVVTEDDTETI-----FEGLNQMAN-GRRPPLL------------VGHPS |. |||||||. . ||| |.. |.| |||.|.|..| .. . | | . . .. |.|||. | RWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPP FVNELLQKCWNQDPGVRLTSTELVEKF . .|.|.||..|| |.. .|..... SMKKLMQDCWDHDPEKRPSFQEILKRL |
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| Kinase | AqueK667.AA | MLK | 301-395 | 32 | 6.4e-17 | 55.34 | In-house | 197-291 (291) | Show / Hide |
Range on Protein: 301-395 Range on HMM: 197-291/291 Sequence Identity: 32% (32 aa) VRYTAPEVL---RGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETIFEGLNQMANGRRPPLLVGHPSFVNELLQKCWNQDPGVRLTSTELVEKF ... ||||. |.. || || |.. ... |||||.|..| .. . .. . .|| |||. . | ..|...||||||. | .. . |... YAWMAPEVIQQFRCEKYS-EKCDVWSWGVVLWEMLTREVPYK--QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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| Kinase | AqueK667.AA | Fer | 300-396 | 22 | 4.7e-14 | 44.35 | In-house | 181-283 (283) | Show / Hide |
Range on Protein: 300-396 Range on HMM: 181-283/283 Sequence Identity: 22% (24 aa) PVRYTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQE---PV------VTEDDTETIFEGLNQMANGRRPPLLVGHPSFVNELLQ-KCWNQDPGVRLTST |.|..|||... ..| |.. | ...|| .. . | .|. ..... . .|...|. ..|... ... .||..|| | | . PIRWLAPETWQTGI-YSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQAR---KWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMK ELVEKFK |...|.| EICQKLK |
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| Kinase | AqueK667.AA | TK | 284-395 | 19 | 6.6e-13 | 38.83 | In-house | 326-486 (486) | Show / Hide |
Range on Protein: 284-395
Range on HMM: 326-486/486
Sequence Identity: 19% (32 aa)
PSNW-------HYYDASDAIHNDPVRYTAPEVLRG--------TSYSTEKRDIFNFAITLWEMLARQ-EPVVTEDDT---------ETIFEGLNQM----
| | . | .. |.|..|||.|.. . |.| |.. | ...||.. . || . . . ..| | .
PM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLC
-------ANGRRPPLLVGHP--------------SFVNELLQKCWNQDPGVRLTSTELVEKF
.. |.| .. | .. .|.|.||. || | | ..|.|..
RSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | AqueK667.AA | Dicty4 | 303-385 | 35 | 7.4e-13 | 39.38 | In-house | 183-263 (277) | Show / Hide |
Range on Protein: 303-385 Range on HMM: 183-263/277 Sequence Identity: 35% (30 aa) YTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVV-TEDDTETIFEGLNQMAN-GRRPPLLVGHPSFVNELLQKCWNQDPGVR ..||||... .| .|| | . |.| |||.| |||| .... .... .| . |||. | . .|.|.||. || .| WMAPEVMMHQPY-NEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRA---VCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHR |
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| Kinase | AqueK667.AA | HH498 | 302-395 | 30 | 9e-13 | 36.43 | In-house | 190-284 (284) | Show / Hide |
Range on Protein: 302-395 Range on HMM: 190-284/284 Sequence Identity: 30% (30 aa) RYTAPEVLR-GTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETIFEGLNQMANGR-RPPLLVG----HPSFVNELLQKCWNQDPGVRLTSTELVEKF |. |||| .. || .| |.| .|. .|||. | | .| ||. . |||. | |.| ||.. | | . . | . RWMAPEVFSQCQKYS-IKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAE----MAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL |
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| Kinase | AqueK667.AA | Dicty5 | 303-399 | 30 | 2.5e-12 | 38.75 | In-house | 169-260 (260) | Show / Hide |
Range on Protein: 303-399 Range on HMM: 169-260/260 Sequence Identity: 30% (30 aa) YTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETIFEGLNQMANGRRPPLLVGHPSFVNELLQKCWNQDPGVRLTSTELVEKFKKIC . |.|. | | ..| |.. |.| ||||..| || | . . . . | || . |. | ||| | | | . .| .. |..| WMACELFNGQPY-HQKCDVYSFGIVLWEMFTRKEPY----DNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII |
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| Kinase | AqueK667.AA | MOS | 302-347 | 41 | 1.2e-11 | 34.63 | In-house | 203-247 (299) | Show / Hide |
Range on Protein: 302-347 Range on HMM: 203-247/299 Sequence Identity: 41% (19 aa) RYTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETI .| |||.|.| |.| ||. |.||.| |..|. | .|| ... TYMAPELLCGDTP-TPKADIYSFGITMWQMQTRETPYHGEDCHHVY |
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| Kinase | AqueK667.AA | DRK | 304-337 | 61 | 2.5e-11 | 34.66 | In-house | 169-201 (258) | Show / Hide |
Range on Protein: 304-337 Range on HMM: 169-201/258 Sequence Identity: 61% (21 aa) TAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEP ||||||| | ||| |.. ||| |||.. || | TAPEVLRNQRY-TEKADVYSFAIVLWECVTRQDP |
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| S_TKc | AqueK667.AA | S_TKc | 171-396 | 20 | 3.4e-11 | -12.72 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 171-396 Range on HMM: 1-231/231 Sequence Identity: 20% (53 aa) RVDGSLIGIGSSDRVRFATHEG--RDVAVKY--SILAREHKELEQEKHDNIAVLLGTGP-NERFIIREFAPY---SLETVLHGSYPH--CYTYEYNHVMH . .|| |. .|. ..| . | ||.| . || . |.. .|.|| |... .. ... |... .| .... .| .. . |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARF WARQTAVGLEYLHSKGFLCPGIKPSN---------------WHYYDASDAIHNDPV---RYTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVVTED ...|.. .|||.||.|.. .||.| .. . . | ||||| .|...| |. . ..|.|||... | YMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--- DTETIFEGLNQMANGRRPPLLVGHPSFVNELLQKCWNQDPGVRLTSTELVE--------KFK . ...|. . |.. . ...||.. || |.| |. . . QMQMMFKKIG-------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| TyrKc | AqueK667.AA | TyrKc | 171-395 | 20 | 1.1e-10 | -50.09 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 171-395
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)
RVDGSLIGIGSSDRVRFATHEGRDVAVKYSILAREHKELEQE---------KHDNIAVLLG--TGP-------NERFIIREFAPY-SLETVLHGSYPHCY
. | .| | .|. .| ..|||| .... .| .|.|| |.| | . .|. |..|. .| |. . |.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--
TYEYNHVMHWARQTAVGLEYLHSKGF------------------------LCPGIKPS-----NWHYYDASD-AIHN--DPVRYTAPEVLRGTSYSTEKR
. ... | | | ||||||.. |. |. . ||... . |.| .|||... ..| |
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KS
DIFNFAITLWEMLAR-QEPVVTE----DDTETIFEGLNQMANGRRPPLLV--------GHPSFVNELLQKCWNQDPGVRLTSTELVEKF
|.. | ...||.. . |.| . . . ..| . .. .|.|. .. . . ..||. || | | .|..|.|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV--KQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
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| Kinase | AqueK667.AA | Pkinase | 302-395 | 20 | 2.2e-09 | 34.28 | Pfam | 176-293 (293) | Show / Hide |
Range on Protein: 302-395 Range on HMM: 176-293/293 Sequence Identity: 20% (25 aa) RYTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETIFEGLNQMANGRRPPLLVGHP------------------------SFVNELLQKC .| ||||.|| .| . | |.. . ..|.||| .. | .. .. .|| . ...| | . . ... .| WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC WNQDPGVRLTSTELVEK--F ...|| |.| ..... | LCKDPKKRPTAEQILQHPWF |
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| Kinase | AqueK667.AA | TKL | 177-276 | 19 | 4.5e-09 | 28.84 | In-house | 1-152 (364) | Show / Hide |
Range on Protein: 177-276
Range on HMM: 1-152/364
Sequence Identity: 19% (32 aa)
IGIGSSDRVRFATHEG----------RDVAVKYSIL---------------------------------AREHKELEQ---EKHDNIAVLLG--TGPNE-
|| |.. | ... | .||||| .| .|. . .|.|| ..| . |.
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------RFIIREFAPY-SLETVLHGSYPHCYTYEYNHVMHWARQTAVGLEYLHSKG
.|. |..| ||. .|| .. ..||...| |..||||..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMN
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| Kinase | AqueK667.AA | MLK | 173-274 | 26 | 9.1e-09 | 26.68 | In-house | 3-142 (291) | Show / Hide |
Range on Protein: 173-274
Range on HMM: 3-142/291
Sequence Identity: 26% (37 aa)
DGSLIGIGSSDRVRFATHEGRD-----VAVKYSI---------------LAREHKELEQEKHDN----IAVLLGT---GPNERFIIREFAPY-SLETVLH
|| ||. | .. ..| |||| . .| ..| .| | | ...|. |.. .|. |.... || .|||
FHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLH
GSYPHCY----------TYEYNHVMHWARQTAVGLEYLHS
| .. . .| |.| || | | |..||||
GARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHS
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| Kinase | AqueK667.AA | TAK1 | 238-275 | 44 | 7.5e-08 | 22.5 | In-house | 85-121 (284) | Show / Hide |
Range on Protein: 238-275 Range on HMM: 85-121/284 Sequence Identity: 44% (17 aa) SLETVLHGSYPHCYTYEYNHVMHWARQTAVGLEYLHSK || .|||. |. . | |.| |..| | |. ||||. SLHNFLHGAKPKWE-YTHAHAMSWMHQCAQGVAYLHSM |
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| Kinase | AqueK667.AA | TK | 204-277 | 15 | 3.8e-05 | 12.38 | In-house | 87-261 (486) | Show / Hide |
Range on Protein: 204-277
Range on HMM: 87-261/486
Sequence Identity: 15% (27 aa)
REHKELEQEK-----HDNIAVLLG----TGP----------NERFIIREFAPY-----SLETVLHGSYPH------------------------------
.| |... . |.|| |.| .| |. |..|. || . |. . |.
EEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY
-------CYTYEYNHVMH-----------------------------------WARQTAVGLEYLHSK------GF
| . | . . ...| | |.|||||| .|
SHESNSPC-PEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNF
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| Kinase | AqueK667.AA | Pkinase_Tyr | 300-395 | 24 | 0.000316 | 14.94 | Pfam | 177-270 (270) | Show / Hide |
Range on Protein: 300-395 Range on HMM: 177-270/270 Sequence Identity: 24% (25 aa) PVRYTAPEVLRGTSYSTEKRDIFNFAITLWEMLA-RQEPVVTEDDTE----TIFEGLNQM-ANGRRPPLLVGHPSFVNELLQKCWNQDPGVRLTSTELVE |.. .|||... ..| | |. | ...||.. ..| . . .| ... .|.| | . | . .|...||..|| | | .|..| PIKWMAPECINYGKFTT-KSDVWSFGVLMWEIFTYGEQP-------TYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHE KF .. QL |
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| Kinase | AqueK667.AA | MOS | 372-397 | 30 | 0.010093 | 4.61 | In-house | 274-299 (299) | Show / Hide |
Range on Protein: 372-397 Range on HMM: 274-299/299 Sequence Identity: 30% (8 aa) ELLQKCWNQDPGVRLTSTELVEKFKK .| |||| . | |... .| QLIQKCWPKQPEQRPSARQLKHELEM |
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| Kinase | AqueK667.AA | DRK | 373-397 | 36 | 0.031943 | 3.37 | In-house | 234-258 (258) | Show / Hide |
Range on Protein: 373-397 Range on HMM: 234-258/258 Sequence Identity: 36% (9 aa) LLQKCWNQDPGVRLTSTELVEKFKK |.. ||| || | . | .| LMNDCWNEDPQHRPSMQECLERLEA |
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| Pkinase | AqueK667.AA | Pkinase | 171-278 | 22 | 0.033401 | 8.87 | Pfam | 1-130 (293) | Show / Hide |
Range on Protein: 171-278 Range on HMM: 1-130/293 Sequence Identity: 22% (29 aa) RVDGSLIGIGSSDRVRFATHEGRD--VAVKYSILAREHKELEQE-------------KHDNIAVLLGTG--PNERFIIREFAPY-----SLETVLH-GSY . |. || ||. .|. ..| | |||| . .|... .|. .|.|| |... ... .. |... .| .... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH PHCYTYEYNHVMHWARQTAVGLEYLHSKGFL | ..... ....|.. ||||.||.|.. GCFY-FSEWECKFYMYQILRGLEYCHSMGII |
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| Kinase | AqueK667.AA | Pkinase_Tyr | 260-277 | 44 | 0.875109 | 3.28 | Pfam | 115-132 (270) | Show / Hide |
Range on Protein: 260-277 Range on HMM: 115-132/270 Sequence Identity: 44% (8 aa) HWARQTAVGLEYLHSKGF ....| | |.|||.||.. QMCWQIAKGMEYLESKNC |
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