Gene AqueK662 (A.queenslandica)

AqueK662

Species: A.queenslandica
Alias: AqueK662
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
AqueK662.AA Protein None 702 None Fasta, JSON
AqueK662.kin_dom Protein Kinase Domain None 100 None Fasta, JSON

Protein domain

Protein domains of AqueK662.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK662.AA Kelch_2 60-107 15 0.000246 20.6 Pfam 1-51 (51) Show / Hide 
Range on Protein: 60-107
Range on HMM: 1-51/51
Sequence Identity: 15% (8 aa)

GVRAYSCTAINDQLYYFGGW---CGHDKCFHNSITQLDTISVQWRELEPTD
.    ... .....| |||.    ... |....|  .|. . .|... . .
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_2 AqueK662.AA Kelch_2 264-297 15 0.177339 9.74 Pfam 14-51 (51) Show / Hide 
Range on Protein: 264-297
Range on HMM: 14-51/51
Sequence Identity: 15% (6 aa)

LVISGGL----DEKNKTIDDWWIFNITRHSWIKLCVHH
....||.    ..... . |.|...   |.| .... .
IYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kinase AqueK662.AA Dicty4 576-654 36 1.5e-14 45.13 In-house 3-89 (277) Show / Hide 
Range on Protein: 576-654
Range on HMM: 3-89/277
Sequence Identity: 36% (32 aa)

TEDELGRGSYGVVTVGIFRGLRVAAKSL--HTIIISDFNLGLFSREMSIASRVRHPNLVQFIGA-T----KVGNPLILTELM-STSL
.|...|.||.| |  |. ||  || | |  | .  . . |  | .| .| .  ||||...| || |    . | ..| ||.| ...|
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNL
Kinase AqueK662.AA Shk 576-671 36 1.1e-13 45.72 In-house 3-104 (269) Show / Hide 
Range on Protein: 576-671
Range on HMM: 3-104/269
Sequence Identity: 36% (37 aa)

TEDELGRGSYGVVTVGIFRGLRVAAKSLHTIIISDFNLGLFSREMSIASRVRHPNLVQFIGA-T-KVGNPLILTELM-STSLNQELHRNRLTNE--QILR
.|| || ||.| |  |. ||  || | .|    .   .  |  | .| |...|||.. | || | . |   | ||||  ..|   ||  . . .   ..|
REDFLGQGSFGKVYKGRCRGKEVAVKVMHKQNFDENTMTSFRKEVHIMSKIFHPNICLFMGACTSQPGKCMIVTELMPKGNLEKLLHDQMVKKPFILYKR

-M
 |
AM
Kinase AqueK662.AA TKL 580-672 21 8.9e-13 42.34 In-house 1-138 (364) Show / Hide 
Range on Protein: 580-672
Range on HMM: 1-138/364
Sequence Identity: 21% (31 aa)

LGRGSYGVVTVGIFRG----------LRVAAKSLHTIIISDFNL-------------------------GLFSREMSIASRVRHPNLVQFIGATK-----
.|.|..|.|  |..||            || | ...   . |..                           . .|. . || ||||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGNPLILTELM-STSLNQELHRNRLTNEQILRMI
          |.. | .|..   ||   ||      .|..|..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWA
Kinase AqueK662.AA TK 574-677 12 3.5e-11 32.97 In-house 1-243 (486) Show / Hide 
Range on Protein: 574-677
Range on HMM: 1-243/486
Sequence Identity: 12% (31 aa)

TLTEDELGRGSYG---VVTVGIFRGL---------------------------RVAAKSLH---TIIISDFNLGLFS---------REMSIASRVR----
   ...||.| .|   .|  |. ||.                           .|| | |.   .    .| .  .          .|.....  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVQFIG-ATKVGN------------PLILTELMS-TS----LNQELHRNR----------------------------------------------
 |||.|...|  |....            ..|..|.|.  .    | . |...|                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------LTNEQILRMI-----------------VAVQV
           ||  . |.|                   ..|.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQI
Kinase AqueK662.AA DRK 581-651 41 4.1e-11 33.92 In-house 8-80 (258) Show / Hide 
Range on Protein: 581-651
Range on HMM: 8-80/258
Sequence Identity: 41% (30 aa)

GRGSYGVVTVGIFRGLRVAAKSLHTIIISDFN-LGLFSREMSIASRVRHPNLVQFIGA-TKVGNPLILTELMS
|||.|| |  |  ||  || | |    | | | |  | ||  . .. |||| .||.|. .    ..| .| |.
GRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMP
Kinase AqueK662.AA LISK 579-637 32 2.2e-10 29.76 In-house 1-64 (296) Show / Hide 
Range on Protein: 579-637
Range on HMM: 1-64/296
Sequence Identity: 32% (21 aa)

ELGRGSYGVVTVGIFR--GLRVAAKSLHT---IIISDFNLGLFSREMSIASRVRHPNLVQFIGA
|.|.|..| |  |  |  |  .| | .|.     . . ..  . ||. .  . |||| |||.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV
Kinase AqueK662.AA CAMK 579-635 16 1.7e-09 26.02 In-house 1-104 (425) Show / Hide 
Range on Protein: 579-635
Range on HMM: 1-104/425
Sequence Identity: 16% (17 aa)

ELGRGSYGVVTVGIFRGLR--------------VAAKSLHTIIIS--------------------------DFNLGLFSREMSIASR-------VRHPNL
.|||||.|.|  .| .                 ||.| . .  ..                          ....  . ||..| ..       ..|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQFI
....
IKLY
Kinase AqueK662.AA Gdt 577-636 30 1.8e-09 28.64 In-house 4-68 (289) Show / Hide 
Range on Protein: 577-636
Range on HMM: 4-68/289
Sequence Identity: 30% (21 aa)

EDELGRGSYGVVTVGIFRGLRVAAKSLHTIIISDFN--------LGLFSREMSIASRVRHPNLVQFIG
.  .. |..|.|  ||.|.. || |    . ... |           . |||.| |...|.| | |||
KEYCSQGTFGMVYKGIWRSSQVAVK---MFKHHYVNYTKTYSQSCDEIYREMDILSKIKHQNIVSFIG
Kinase AqueK662.AA MLK 574-651 23 2.2e-09 28.84 In-house 1-93 (291) Show / Hide 
Range on Protein: 574-651
Range on HMM: 1-93/291
Sequence Identity: 23% (22 aa)

TLTEDELGRGSYGVVTVGIFRGLR-----VAAKSLHTIIISDFNL-----GLFSREMSIASRVRHPN----LVQFIGA-TKVGN-PLILTELMS
 ...  .| ||.|.|  | .|. .     || |  .. |. |          | .|  ......|||     .|| |. .. ..  .|..| ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCE
Kinase AqueK662.AA CZAK 577-650 32 6.1e-09 28.77 In-house 4-84 (279) Show / Hide 
Range on Protein: 577-650
Range on HMM: 4-84/279
Sequence Identity: 32% (26 aa)

EDELGRGSYGVVTVGIFRGLRVAAKSLHTIIISDFNL----GLFSREMSIASRVRHPNLVQFIGATKVGN---PLILTELM
. . |.| .| |  .  ||  || | .| .   .         | .| || |  .||| |||.||   ..     | .| |
GQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWM
Pkinase_Tyr AqueK662.AA Pkinase_Tyr 573-671 26 1e-06 23.33 Pfam 1-116 (270) Show / Hide 
Range on Protein: 573-671
Range on HMM: 1-116/270
Sequence Identity: 26% (31 aa)

VTLTEDELGRGSYGVVTVGIFR------GLRVAAKSLHTIIISDFN--LGLFSREMSIASRV-RHPNLVQFIGATK-VGNP---LILTELMST-SLNQEL
.|.   .||.|..|.|  |. .      .. || |.|     .. .  .  | ||..| .   .|||.|...|.    | |   .| .|.|   .|   |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HRN-----RLTNEQILRM
...     .|| ...| |
RKHREDKQPLTMKDLLQM
Kinase AqueK662.AA Pkinase 574-672 16 0.000667 14.88 Pfam 1-114 (293) Show / Hide 
Range on Protein: 574-672
Range on HMM: 1-114/293
Sequence Identity: 16% (19 aa)

TLTEDELGRGSYGVVTVGIFRGLR--VAAKSLHTIIISDFNLGLFSR--EMSIASRVRHPNLVQFIGATK-VGNPLILTELMST-----SLNQELH---R
  ..  .|.||.|.|  .. .| .  || | .    ...  .    |  | .|  |..||| |.....    ... . .|..       .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NRL--TNEQILRMI
...  . ... ...
GCFYFSEWECKFYM
Kinase AqueK662.AA S_TKc 574-702 8 0.000702 -120.01 SMART 1-220 (231) Show / Hide 
Range on Protein: 574-702
Range on HMM: 1-220/231
Sequence Identity: 8% (19 aa)

TLTEDELGRGSYGVVTVGIFRG--LRVAAKSLHTIIISDFNLGLFSREMSIASRVRHPNLVQFIGATKVGNPLILTELMST---SLNQELHRNR------
    ...|.|..|.|  .. ..   .|| | ..           . ||..| .. .|||.|.....   ..  . .|....   .| . .....      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNEQILRMIVAV----------------------------------------------------QVLEYST---------------------------
 ..  .. ...  .                                                     .  |..                           
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFPQMQM

IYRNNVSDTTY-IVLNLLTV-----------A
.... .|.    .. ..|..           .
MFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ