Gene AqueK633 (A.queenslandica)
AqueK633
Species: A.queenslandica
Alias: AqueK633
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK633.AA | Protein | None | 560 | None | Fasta, JSON |
| AqueK633.kin_dom | Protein Kinase Domain | None | 174 | None | Fasta, JSON |
Protein domains of AqueK633.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK633.AA | TKL | 64-289 | 21 | 2.1e-35 | 123.94 | In-house | 75-364 (364) | Show / Hide |
Range on Protein: 64-289 Range on HMM: 75-364/364 Sequence Identity: 21% (67 aa) EIILHSRQRHPNIVQLLG--VGHPD-------------LTIVTEYFPLG--LSVLLDDKRHKIPDWMK-SRLMLDISQGLRYLHSQT------KPIIHFG || ..|| |||||||..| |. | ||.|| | | |..|. | . |..|||..|. ||||.. .|||| EIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRD LTSNNILLTEHFQ--------------AKIADLATSRAFFDPS--------------------LTNLDYGSFIFMPPELFSPDDREEQ----------RK |.|.|||. |... .||.|. .|| .. . |. |.. .|.||.. .. .. .. LKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFE YDVKFDVFSFGCIMIHILSQQYPIPSEQYIFSNGNEENSINQ-PTLEFVQVS-------EWKRRQSYLSHLP--------------SGHTLLPIVEKCLA |. | ||.||| .. ||. . . . . .... .. .. .| . . . ..| . YSEKCDVYSFGIVLWEILTRCR-----------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWD NYPQDRPESSELVTDI |..|| .|.. . HDPEKRPSFQEILKRL |
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| Kinase | AqueK633.AA | TKL-Unique | 45-218 | 25 | 6.9e-31 | 106.24 | In-house | 27-233 (290) | Show / Hide |
Range on Protein: 45-218 Range on HMM: 27-233/290 Sequence Identity: 25% (54 aa) KINKPDEDSKQAFLVKLSHEIILHSRQR-HPNIVQLLGVGH------PDLTIVTEYFPLG-LSVLLD---------DKRHKIPDWMKSRLMLDISQGLRY .... ||| .. ... |. . .. . |||||.. |. . |.. ||.||.|.| | .|. . .|.. .. .. .||.||. | QFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYY LHSQTKPIIHFGLTSNNILLTEH-----FQAKIADLATSRAFFDPSLTNLD----------YGSFIFMPPELFSPDDREEQRKYDVKFDVFSFGCIMIHI ||. .||||. |.| |.|.... ...||.| .|. . ... |||. |.||... .|. | ||.||| ... | LHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF----CQYSEKSDVYSFGIVLWEI LSQQY------P .. . | ATRKITKTYKKP |
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| Kinase | AqueK633.AA | LRRK | 63-218 | 34 | 3.6e-24 | 82.38 | In-house | 106-282 (351) | Show / Hide |
Range on Protein: 63-218
Range on HMM: 106-282/351
Sequence Identity: 34% (63 aa)
HEIILHSRQRHPNIVQLLGVGHPDLTIVTEYFPLG-LSVLLDDKR-HKI----PD--WM-KSRLMLDISQGLRYLHSQTKPIIHFGLTSNNILL---T--
||. . |. .|||||.|.|... |..|.|| |.| |. .| .|. ... .. || | ...|.|. |..||||.. |||| |.| |||| .
HEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQN
-------EHFQAKIADLATSR--AFFDPSLTNLDYGSFIFMPPELFSPDDREE-QRKYDVKFDVFSFGCIMIHILSQQ-YP
.| ||||| .|| . | ..... | ...| || |.. |. | |..||| |. ..|. | |
HSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIM----RYNGEEEYTEKVDCYSFGMILWELLTRQHHP
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| Kinase | AqueK633.AA | MLK | 72-209 | 30 | 1.6e-21 | 71.51 | In-house | 63-226 (291) | Show / Hide |
Range on Protein: 72-209
Range on HMM: 63-226/291
Sequence Identity: 30% (51 aa)
RHPN----IVQLLGV--GHPD-LTIVTEYFPLG-LSVLLDDKRH-------------KIPDWMKSRLMLDISQGLRYLHS-QTKPIIHFGLTSNNILLTE
.||| |.|..|| .| . ||.|| . | |. .| ..| .. . . .|....|. |||| . |||||. | | |||..|
SHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDE
------HFQAKIADLATSRAFFDP-S-LTNLDYGSFIFMPPELFSPDDREEQRKYDVKFDVFSFGCIM
| ..||.| ||| . . . .. |....| || .. . . ||. | ||.|.| ..
ICHDMHHGTLKICDFGTSRDWHQMCTNMMSN-AGTYAWMAPEVIQ---QFRCEKYSEKCDVWSWGVVL
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| Kinase | AqueK633.AA | HH498 | 114-218 | 34 | 1e-18 | 55.63 | In-house | 123-225 (284) | Show / Hide |
Range on Protein: 114-218 Range on HMM: 123-225/284 Sequence Identity: 34% (37 aa) KSRLMLDISQGLRYLHS-QTKPIIHFGLTSNNILLTEHFQAKIADLATSRAFFDPSLTNLDY--GSFIFMPPELFSPDDREEQRKYDVKFDVFSFGCIMI | .. .|. .| .|||. ..|||| |.| |||. | |..|| || | |. | .| || || ||. | ||||.. .. KMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS-----QCQKYSIKVDVFSYAMCIW HILSQQYP ... | EMHTREVP |
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| Kinase | AqueK633.AA | DRK | 57-157 | 40 | 6.6e-18 | 57.26 | In-house | 40-143 (258) | Show / Hide |
Range on Protein: 57-157 Range on HMM: 40-143/258 Sequence Identity: 40% (43 aa) FLVKLSHEIILHSRQRHPNIVQLLG--VGHPDLTIVTEYFPLG-LSVLLDDKRHKIPDW-MKSRLMLDISQGLRYLHSQTKPIIHFGLTSNNILLTEHFQ || . || | .. |||||.| .| || |..|| |.| | | | .. || ..|.|. |. |||. . ||| | | | | ||.| FLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEM-DWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQ AKIAD |.|| VKVAD |
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| Kinase | AqueK633.AA | Dicty4 | 42-158 | 27 | 3.4e-16 | 50.67 | In-house | 28-158 (277) | Show / Hide |
Range on Protein: 42-158 Range on HMM: 28-158/277 Sequence Identity: 27% (36 aa) KKPKINKPDEDSKQAFLVKLSHEIILHSRQRHPNIVQLLGVGH------PDLTIVTEYFPLG--LSVLLD-----DKRHKIP-DWMKS--RLMLDISQGL ||.. .. ... ...| . .|. . . |||||....| ... ||||| | | .|.|.| .. |.. .|. |...|. .|. KKLNNHN--QNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGM RYLHSQTKPIIHFGLTSNNILLTEHFQAKIADL .||. . ||| | | |.| .....|..|. NWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDF |
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| Kinase | AqueK633.AA | Dicty5 | 64-218 | 31 | 5.5e-16 | 51.5 | In-house | 46-202 (260) | Show / Hide |
Range on Protein: 64-218 Range on HMM: 46-202/260 Sequence Identity: 31% (52 aa) EIILHSRQR--HPNIVQLLGVGHPD---LTIVTEYFPLG-LSVLLDDKRH----KIPDWMKSRLMLDISQGLRYLHSQTKPIIHFGLTSNNILLTEHFQA |. . | |||.. .| . . . .|||| | |. .| |.| | . . .|| |..|.||| . ||| | |.|.|.|| ... EVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHS--MNIIHRDLKSMNFLITENWKI KIADLATSR-AFFDPSLTNLDYGSFIFMPPELFSPDDREEQRKYDVKFDVFSFGCIMIHILSQQYP || | ||| | .. | .| .||| . |. | ||.||| . .. . | KIIDFGTSRFVDNRYHMT-MHVGTQCWMACELF------NGQPYHQKCDVYSFGIVLWEMFTRKEP |
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| S_TKc | AqueK633.AA | S_TKc | 14-292 | 21 | 3.3e-15 | 46.04 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 14-292
Range on HMM: 1-231/231
Sequence Identity: 21% (64 aa)
SHSDVLIGS-SGGRSVTVEVKVRGLKCTGKKPKINKPDEDSKQAFLVKLSHEIILHSRQRHPNIVQLLGVGH-PDLTIVTEYFPL---GLSVLLDDKRHK
. .||. . |. . | | .. |. | .. || .... .|||||.|..| . .| .|.|| . | ........
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRH
-----IPDWMKSRLMLDISQGLRYLHSQTKPIIHFGLTSNNILLTEHFQAKIADLATSRAFFDPSLTNLDYGSFIFMPPELFSPDDREEQRKYDV-KFDV
.| . ..| | ..| |.||. ||| | ||||.| . ||.| .| . . |. .|.||.. .|. | |.
GLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---------GYGKCKCDW
FSFGCIMIHILSQQYPIPSEQYIFSNGNEENSINQPTLEFVQVSEWKRRQSYLSHLPSGHTLLPIVEKCLANYPQDRPESSELVT-D-----IEAV
|.|||.. |. . | | |. . | .. . .. ...||| |..|| |. . . . .
WSCGCILYEMLCGYPPFP----------------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | AqueK633.AA | RIPK | 72-218 | 30 | 5e-15 | 47.61 | In-house | 54-227 (290) | Show / Hide |
Range on Protein: 72-218
Range on HMM: 54-227/290
Sequence Identity: 30% (53 aa)
RHPNIVQLLGVGHPD--------LTIVTEYFPLG-LSVLLDDKR----HKIPDWMKSRLMLDISQGLRYLHSQTKPIIHFGLTSNNILLTEHFQAKIADL
|. .||...|. . ||.|| . | |. .| | | .| . |. || | ||||.. |||| | |||. .| .||||.
RCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADF
------ATSRAFFDPS-------LTNLDY-GSFIFMPPELFSPDDREEQRKYDVKFDVFSFGCIMIHILSQQYP
.| . | . .. | ..||||.| .| . . . |.|| ||. .| .|.| |
GLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHP
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| Kinase | AqueK633.AA | Ciliate-E2-Unclassified | 87-225 | 20 | 2.7e-14 | 46.0 | In-house | 96-276 (352) | Show / Hide |
Range on Protein: 87-225 Range on HMM: 96-276/352 Sequence Identity: 20% (38 aa) LTIVTEYFPLG-LSVLLDDK----------------RHKIPDWMKS-----RLMLDISQGLRYLHSQTKPIIHFGLTSNNILLTEH---FQAKIADLATS . ||.||.. | |. . .. |..... . ... | ||| |||.. ||| .. .|||... .. ||.|. | IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGIS R----------------AFFDPSLTNLDYGSFIFM----PPELFSPDDREEQRKYD----VKFDVFSFGCIMIHILSQQYPIPSEQYI . ..... ... |. ..| .||.. .. .|| | |..|.|.|. .| ..|| ...... KKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL------QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCE |
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| Kinase | AqueK633.AA | Pkinase | 45-218 | 26 | 1.8e-13 | 48.68 | Pfam | 31-211 (293) | Show / Hide |
Range on Protein: 45-218 Range on HMM: 31-211/293 Sequence Identity: 26% (51 aa) KINKPDEDSKQ---AFLVKLSHEIILHSRQRHPNIVQLLGVG--HPDLTIVTEYFPLGLSVLLDDK-------RHKI--PDWMKSRLMLDISQGLRYLHS .|.|..|.|.. ... || .. | .|||||.|... .... .|.|| . ||. ..| . . .. ..| . |. | .|| |.|| IIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS QTKPIIHFGLTSNNILLTEHFQA----KIADLATSR---AFFDPSLTNLDYGSFIFMPPELFSPDDREEQRKYDVKFDVFSFGCIMIHILSQQYP . ||| | . |||. .. . ||.| .. .. .| . |. .|.||. ....|. | |..|.|||.. |. . | M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC-GTPWYMAPEVIR-----GGQYYGPKVDMWSCGCILYEMLCGRPP |
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| TyrKc | AqueK633.AA | TyrKc | 8-289 | 21 | 1.4e-10 | -51.66 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 8-289 Range on HMM: 1-280/280 Sequence Identity: 21% (71 aa) LLLKDV----SHSDVLIGSSGGRSVTVEVKVRGLKCTGKKPKINKPDEDSKQAFLVKLSHEIILHSRQ--RHPNIVQLLGVGH---------PDLTIVTE . |... | | ... |. | .. . . .|. . .. .|||||.|.|| . | ||.| ITLGKKLGEGAFGEVYKGTWK------------IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVME YFPLG-LSVLLDDKRHKIPDWMKSRLMLDISQGLRYLHSQTKPIIHFGLTSNNILLTEHFQAKIADLATSRAFFDP-------SLTNLDY---GS--FIF | |.| | | ..|.|.. . ...|..| .||||. ..|| | |.|..| ...||.| ||. | . | . YMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI --MPPELFSPDDREEQRKYDVKFDVFSFGCIMIHILS---QQYPI-----PSEQYIFSNGNEENSINQPTL----EFVQVSEWKRRQSYLSHLPSGHTLL |.|| . .|. | ||.||| | |.. | || | | .. . . . || . . RWMAPECI------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------F-VCCPDEMY PIVEKCLANYPQDRPESSELVTDI | ..| . | ||| ||.. .. QIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | AqueK633.AA | Pkinase_Tyr | 72-157 | 32 | 1e-06 | 23.22 | Pfam | 62-154 (270) | Show / Hide |
Range on Protein: 72-157 Range on HMM: 62-154/270 Sequence Identity: 32% (31 aa) RHPNIVQLLGVGH---PD--LTIVTEYFPLG-LSVLLDDK---RHKIPDWMKSRLMLDISQGLRYLHSQTKPIIHFGLTSNNILLTEHFQAKIAD .|||||.|.|| . ||.|| |.| | | .. ..... .. ..|..|. ||.|. .|| | |.|.|| ...||.| HHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICD |
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| Kinase | AqueK633.AA | LRRK | 269-291 | 26 | 0.289378 | 0.21 | In-house | 329-351 (351) | Show / Hide |
Range on Protein: 269-291 Range on HMM: 329-351/351 Sequence Identity: 26% (6 aa) EKCLANYPQDRPESSELVTDIEA ..| .. |..|| .|. | .. QHCWQHDPKKRPHFSQIVKRLSQ |
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| DUSP | AqueK633.AA | DUSP | 324-418 | 25 | 7e-20 | 68.62 | Pfam | 1-96 (96) | Show / Hide |
Range on Protein: 324-418 Range on HMM: 1-96/96 Sequence Identity: 25% (26 aa) DDIWCLVSSHWFEKWTKFIDIALRVGIDGCNRSSHPGPV-T--NFTLIKFIKFQPT---KMKK-DFTENVDYILIPEIGWDLLIQWYGISEKSMRLSRKV | | |.|. |...|..... . . |||. . | ... .. . ..|. . |..||...|| |..|.||||. |.. . ||| GDKWYLISMKWWNQWKQYVYYDNNDNDNM-----RPGPIEDDKNSDILCDHDSCFKYNYQLKPHNLQEGKDYVIVPEEVWNFLYQWYGC-EGGPPIPRKV VK .. IC |
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| DUSP | AqueK633.AA | DUSP | 320-420 | 21 | 2.3e-12 | 48.31 | SMART | 1-114 (114) | Show / Hide |
Range on Protein: 320-420 Range on HMM: 1-114/114 Sequence Identity: 21% (26 aa) KLVKDDI-WCLVSSHWFEKWTKFID---IALRVGIDGCNRSSH-----------PGPVTNFTLIKFIK----FQPTKMKKDFTENVDYILIPEIGWDLLI .. . |. |...|..|...| ... | . .|. |||..|...|. . |.. |..||.|||. |. | NWKEGDTRWYCISMRWWRQWQDYVEHQHCC------GQAFDSWCMYGEGSHGKFPGPIDNWDIICSHGHTWNANDWRLKWHLYEGCDYVLIPQEVWNYLV QWYGISEKSMRLSRKVVKAR |||. . . . |.|. . RWYGGGPGQEPIMRCVICQG |
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