Gene AqueK630 (A.queenslandica)
AqueK630
Species: A.queenslandica
Alias: AqueK630
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK630.AA | Protein | None | 369 | None | Fasta, JSON |
| AqueK630.kin_dom | Protein Kinase Domain | None | 146 | None | Fasta, JSON |
Protein domains of AqueK630.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK630.AA | TKL | 1-204 | 22 | 7.7e-36 | 125.39 | In-house | 79-355 (364) | Show / Hide |
Range on Protein: 1-204 Range on HMM: 79-355/364 Sequence Identity: 22% (64 aa) HSQQRHPNIVLLIG-VYYPPR----------SQLPMLVMEYLPL-S-LTQCLEREELPLQMKYSILLDVAKGLCYLHGKR------PPIVHRDLTANNVL .|. ||||||...| . .|| . ...|||| | | | . . .. . .. ||.|.|..||| .. |||.||||. .|.| MSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNIL LTSSYS--------------AKISDLGVSRLVDTFKKHHLTM------------------APGNAMVMPPEALKDNP---------------VYDHKLDV . . . .||.|.| || ... .. || |. |.||.|.... |. | || VDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDV FSYGCLILHVLTGQFPEPTNQFVPEPGKEKSFTKALEWDRRSNYIKDLP--------------KENELLPLARDCLNDVPTDRP .|.| .. .||.. |. . . |. . | .... .. .| .. |. || . |..|| YSFGIVLWEILTRCRPYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRP |
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| Kinase | AqueK630.AA | TK | 5-141 | 17 | 5.4e-28 | 90.3 | In-house | 101-384 (486) | Show / Hide |
Range on Protein: 5-141
Range on HMM: 101-384/486
Sequence Identity: 17% (49 aa)
RHPNIVLLIGVYYPPRS----------QLPMLVMEYLPL-----SLTQCLE--REE--------------------------------------------
.||||| |.|| ... . .|.|||| |. || . | |..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-------------------------------LPLQMKYSILLDVAKGLCYLHGKRP----PIVHRDLTANNVLLTSSYS-----------AKISDLG---
|... . . ...|.|. ||| |. .||||| | |.|..... .||.| |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
-----VSRLVD---TFKKHHLTMAPGNAMV-----------------------MPPEALKDNP--------VYDHKLDVFSYGCLI
.| .. ... ..... |.||.|.|. .. .| ||.|.|.|.
QGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLM
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| Kinase | AqueK630.AA | HH498 | 46-150 | 39 | 3.2e-27 | 83.01 | In-house | 120-225 (284) | Show / Hide |
Range on Protein: 46-150 Range on HMM: 120-225/284 Sequence Identity: 39% (42 aa) LQMKYSILLDVAKGLCYLHG-KRPPIVHRDLTANNVLLTSSYSAKISDLGVSRLVDTFKKHHLTMAPGNAMVMPPEALKDNPVYDHKLDVFSYGCLILHV || | | .|||.| ||| .||.||||. |.|. |.. | | || | .| ||| | || . . |. | |||||. | LQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEM LTGQFP .|. | HTREVP |
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| Kinase | AqueK630.AA | TKL-Unique | 5-138 | 29 | 1.3e-26 | 90.93 | In-house | 53-215 (290) | Show / Hide |
Range on Protein: 5-138 Range on HMM: 53-215/290 Sequence Identity: 29% (49 aa) R-HPNIVLLIGVYY---PPRSQLPMLVMEYLPL-SLTQCLE-----------REELPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSS--- . |||||...|. .. ... .||||.|. || | .|..|..... .|.|.|..||| . ||| ||||. |.|... HYHPNIVHYMGYCMDHQVYPPNM-CIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNI --YSAKISDLGVSRLVDTFKKHHLTMA--------PGNAMVMPPEALKDN-PVYDHKLDVFSYG ...||.| | |.. .. | ... |.. |.|| |..| |. | ||.|.| AEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFG |
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| Kinase | AqueK630.AA | LRRK | 5-150 | 34 | 1.1e-25 | 87.81 | In-house | 115-282 (351) | Show / Hide |
Range on Protein: 5-150
Range on HMM: 115-282/351
Sequence Identity: 34% (59 aa)
RHPNIVLLIGVYYPPRSQLPMLVMEYLPL-SLTQCLE---REE-------LPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSS--------
.||||| |.|. |. ..||||.|. .| . |. . . .. ..|. | |..|||. ||| ..|||.||||. |.|| ||
NHPNIVSLKGFCIHPL----CMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNY
----YSAKISDLGVSRLVDTFKKHHLTMAPGNAMVMPPEALKDN--PVYDHKLDVFSYGCLILHVLTGQ-FP
. |||.| | ||. .|.. . || | || ...| .|. | |..|.| .. . ||.| .|
PNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
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| Kinase | AqueK630.AA | Pkinase_Tyr | 5-141 | 30 | 6.8e-25 | 84.93 | Pfam | 62-204 (270) | Show / Hide |
Range on Protein: 5-141 Range on HMM: 62-204/270 Sequence Identity: 30% (46 aa) RHPNIVLLIGVYYPPRSQ-LPMLVMEYLPL-SLTQCLERE-----ELPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSR .||||| |.|| .. . . ...|||| |. .| | . |..... .. ...|||. ||. |. ..|||| | |.|.|.. .||.| | .| HHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLAR LV-----DTFKKHHLTMAPGNAMVMPPEALKDNPVYDHKLDVFSYGCLI .. ..|.. .. | | .||..... . .| || |.| |. DIYNDDYY-YRKRGGGKLPIKWM--APECINYGK-FTTKSDVWSFGVLM |
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| Kinase | AqueK630.AA | Pkinase | 5-213 | 20 | 5.1e-23 | 82.47 | Pfam | 58-293 (293) | Show / Hide |
Range on Protein: 5-213
Range on HMM: 58-293/293
Sequence Identity: 20% (50 aa)
RHPNIVLLIGVYYPPRSQLPMLVMEYLPL-----SLTQCLE-REELPL--QMKY--SILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSA----KI
.||||| |..... .. . .||||.. .| .. ... .. ... .... ...|| |.| . |.|||| |.|. . . ||
NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKI
SDLGVSRLVDTFKKHHLTMAPGNAMVMPPEALKDNPVYDHKLDVFSYGCLILHVLTGQFPEPTN-QFVPEPGKEKSFTKALEWDRRSNYIKDLPKE----
.| |.....|. ... .| | |.|| ..... |..| |..|.||.. .|.|..| | . . . . . . .. . .... .. ..
CDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFF
-------------NELLPLARDCLNDVPTDRP--EMIYSFEFM
|.. . ..||. |..|| | | ...
RHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
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| Kinase | AqueK630.AA | TK-Unique | 5-141 | 29 | 1.8e-21 | 70.91 | In-house | 62-229 (294) | Show / Hide |
Range on Protein: 5-141 Range on HMM: 62-229/294 Sequence Identity: 29% (51 aa) RHPNIVLLIGVYYPPRSQLPMLVMEYLPLS-----LTQCL-----------------------EREELPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLT .||||| ..|. . . .|..|||.| . | .| ..|.. .. |... ..|.|. ||.. | |||||| DHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLC ANNVLLTSSYSAKISDLGVSRLVDTFKKHHLTMA----PGNAMVMPPEALK--DNPVYDHKLDVFSYGCLI | |||||. . .||.|.| .| |.| . . | . . |.||.|| ... . | || |.|.|. ARNVLLTEDKVCKICDFGMARDVYT--NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLM |
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| Kinase | AqueK630.AA | RIPK | 5-151 | 26 | 3e-21 | 69.15 | In-house | 54-228 (290) | Show / Hide |
Range on Protein: 5-151 Range on HMM: 54-228/290 Sequence Identity: 26% (47 aa) RHPNIVLLIGVYYPP----RSQLPMLVMEYLPL-SLTQCLEREE------LPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDL |. .|| . |. . ..|. .|||| . || | .. .|. . .. .. | ||||.. ||| |||| |.|. . . .||.|. RCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADF GVSRLVDTFKKHH----------LTMAP--GNAMVMPPEALK---DNP--VYDHKLDVFSYGCLILHVLTGQFPE |.. . . | . .. | ||||.. .| | . | || |.. .. |||. |. GLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPY |
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| Kinase | AqueK630.AA | MLK | 5-150 | 25 | 3.2e-21 | 70.48 | In-house | 63-235 (291) | Show / Hide |
Range on Protein: 5-150 Range on HMM: 63-235/291 Sequence Identity: 25% (46 aa) RHPN-----IVLLIGVYYPPRSQLPMLVMEYLPL-SLTQCLEREE---------------LPLQMKYSILLDVAKGLCYLHG-KRPPIVHRDLTANNVLL .||| |... . || . .||||.. || | .. ... . .. |..|.|. ||| ...||.|||| |.|. SHPNNHPCIIQFYGVCLQPP--CHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILI TS------SYSAKISDLGVSRLVDTFKKHH---LTMAPGNAMVMPPEAL--KDNPVYDHKLDVFSYGCLILHVLTGQFP . .||.| |.|| ..... . ..|.. | ||.. . . |. | ||.|.| .. .||.. | DEICHDMHHGTLKICDFGTSR----DWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP |
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| Kinase | AqueK630.AA | LISK | 4-138 | 29 | 3.6e-21 | 65.36 | In-house | 53-226 (296) | Show / Hide |
Range on Protein: 4-138 Range on HMM: 53-226/296 Sequence Identity: 29% (53 aa) QRHPNIVLLIGVYYPPRSQLPMLVMEYLP-LSLTQCLERE-----ELPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSS----YSAKISDL .|||||| .||.| .|| ..| || |.| | .. || . . .| ||.|.|. ||| . |.||||...|.|. . ...|. |. LRHPNIVQFMGVCYHNDGQL-HIVTEYINGGDLHQYLKDMDKHKIPLPWPQRVKIALDIACGMSYLHSMN--IIHRDLKSKNCLVRENDNNQWRIKVCDF GVSRLVDTFK----------------------------------KHHLTMAPGNAMVMPPEALKDNPVYDHKLDVFSYG | |..| . | ..|. |.. |.|| |.. || . ||||.| GFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTIC-GTPYWMAPEMLLGQS-YDESCDVFSFG |
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| Kinase | AqueK630.AA | DRK | 2-138 | 33 | 1.7e-18 | 59.29 | In-house | 52-189 (258) | Show / Hide |
Range on Protein: 2-138
Range on HMM: 52-189/258
Sequence Identity: 33% (47 aa)
SQQRHPNIVLLIGVYYPPRSQLPMLVMEYLPL-SLTQCLEREELPLQ--MKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSRL
.| |||||.. .| | . . .|||.|. || . | | . .. .. .|.|||. |||. | |.|||| | | .. |..| | |
CQLRHPNICQFMGTCNNPPD--ICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTR
VDTFKKHHLTMAP-GNAMVMPPEALKDNPVYDHKLDVFSYG
| | .| . | || | . . | | ||.|..
FKKHKQHKFAMTMCGTPCWTAPEVLRNQR-YTEKADVYSFA
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| Kinase | AqueK630.AA | S_TKc | 1-213 | 21 | 2.4e-12 | 4.21 | SMART | 19-231 (231) | Show / Hide |
Range on Protein: 1-213 Range on HMM: 19-231/231 Sequence Identity: 21% (54 aa) HSQQ-----------------------RHPNIVLLIGVYYPPRSQLPMLVMEYLPL---SLTQCLEREE-------LPLQMKYSILLDVAKGLCYLHGKR . .||||| |..|.. . .||||.. .| . ... .| . ... ....| |.| . RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH- PPIVHRDLTANNVLLTSSYSAKISDLGVSRLVDTFKKHHLTMAPGNAMVMPPEALKDNPVYDH-KLDVFSYGCLILHVLTGQFPEPTNQFVPEPGKEKSF |.|||| |.||.. ||.| |..|.. | | |.|| | |.. | |. | ||.. |.|. | | .. | -GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMF TKALEWDRRSNYIKDLPKENELLPLARDCLNDVPTDRPEMIYSFE---------FM | . |.. . | ||. |..|| .. .. KKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | AqueK630.AA | TyrKc | 2-213 | 22 | 2.9e-12 | -24.3 | SMART | 9-280 (280) | Show / Hide |
Range on Protein: 2-213 Range on HMM: 9-280/280 Sequence Identity: 22% (64 aa) SQQ--------------------------------------RHPNIVLLIGVYYPP-----RSQLPMLVMEYLPL-SLTQCLEREE--LPLQMKYSILLD . . .||||| |.|| . .. .|.|||| |. .| . | . . |... . |. .. EGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQ VAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSRLVDTF------KKHHLTMA--PGNAMV----MPPEALKDNPVYDHKLDVFSYGCLILH .|.| ||| | ...|||| | |.|... . .|||| | || .. |. .. |..|. |.||..... .. .| ||.|.| .. IACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG-KFTTKSDVWSFGVCMWE VLT-GQFPEPTNQFVPEPGKEKSFTKALEWDRRSNYIKDLPK---------ENELLPLARDCLNDVPTDRPEMIYSFEFM ..| || | | . .| . ..|. .. .. . | |. . ..| . | ||| . |.. IFTYGQQPYPGMIQQ-----MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | AqueK630.AA | LRRK | 194-215 | 22 | 0.010092 | 5.44 | In-house | 330-351 (351) | Show / Hide |
Range on Protein: 194-215 Range on HMM: 330-351/351 Sequence Identity: 22% (5 aa) DCLNDVPTDRPEMIYSFEFMEQ .| . |..|| ... .....| HCWQHDPKKRPHFSQIVKRLSQ |
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| Kinase | AqueK630.AA | DRK | 191-215 | 40 | 0.27445 | 0.16 | In-house | 234-258 (258) | Show / Hide |
Range on Protein: 191-215 Range on HMM: 234-258/258 Sequence Identity: 40% (10 aa) LARDCLNDVPTDRPEMIYSFEFMEQ | ||.| |. || | | .| LMNDCWNEDPQHRPSMQECLERLEA |
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