AqueK625

Species: A.queenslandica
Alias: AqueK625
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH498

Sequence

Name Sequence Type Origin Length Description Download
AqueK625.AA Protein None 117 None Fasta, JSON
AqueK625.kin_dom Protein Kinase Domain None 116 None Fasta, JSON

Protein domain

Protein domains of AqueK625.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK625.AA TKL 1-116 19 1.5e-25 88.94 In-house 161-364 (364) Show / Hide
Range on Protein: 1-116
Range on HMM: 161-364/364
Sequence Identity: 19% (39 aa)

IIHRDVSSANVLLENKWK--------------TKISDFGSAKFARA----------------------AVTEAPGAAVYSAPESIR--------------
|||||  |.|.|. ..|.               ||.||| ..|                         .     |   . ||| .|              
IIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEF

--TRKQTTKMDSYSYGVLLCEMITCHFPNA-EKFE------------TVKV-----------------------SSPQLYELIVLCINEEPDKRPTMSEI
   .. ..|.| ||.|..|.|..|.  | . ....             . .                         |.. .|.  | ...|.|||...||
CKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEI

ILKL
. .|
LKRL

Kinase AqueK625.AA TK 1-116 16 8.1e-20 62.41 In-house 261-486 (486) Show / Hide
Range on Protein: 1-116
Range on HMM: 261-486/486
Sequence Identity: 16% (37 aa)

IIHRDVSSANVLLENKWK-----------TKISDFGSAK-----FARAA-------VTEAPGAAV-------------------------YSAPESIR--
..|||.   |.|. .. .            ||.||| ..      ||.        ... .|...                         . |||...  
FVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDR

-------TRKQTTKMDSYSYGVLLCEMIT---CHFPN----------------AEKFET---------------------VKVSS-------------PQ
       ..| ||| | .|.|||. |. |     ..                  |. ..                     .  ..             . 
VFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEE

LYELIVLCINEEPDKRPTMSEIILKL
.|.|.  | ...|..|||.|..  .|
YYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK625.AA MLK 1-76 34 9.7e-14 44.16 In-house 148-235 (291) Show / Hide
Range on Protein: 1-76
Range on HMM: 148-235/291
Sequence Identity: 34% (30 aa)

IIHRDVSSANVLLEN------KWKTKISDFGSAKFARAA---VTEAPGAAVYSAPESI---RTRKQTTKMDSYSYGVLLCEMITCHFP
|||||  | |.|. .      . . ||.||| ...        . ..| . . ||| |   |  | . | | .|.||.| ||.|.  |
IIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP

Kinase AqueK625.AA Dicty5 1-72 40 3.4e-13 41.78 In-house 125-198 (260) Show / Hide
Range on Protein: 1-72
Range on HMM: 125-198/260
Sequence Identity: 40% (30 aa)

IIHRDVSSANVLLENKWKTKISDFGSAKF--ARAAVTEAPGAAVYSAPESIRTRKQTTKMDSYSYGVLLCEMIT
|||||. | |.|.   || || |||   |  .|   |   |   . |.|    .  . | | ||.|. | ||.|
IIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFT

Kinase AqueK625.AA Frk 2-72 35 3.9e-12 37.99 In-house 120-197 (260) Show / Hide
Range on Protein: 2-72
Range on HMM: 120-197/260
Sequence Identity: 35% (28 aa)

IHRDVSSANVLLENKWKTKISDFGSAK-FARAAV------TEAPGAAVYSAPESIRTRKQTTKMDSYSYGVLLCEMIT
||||.   |||....   || ||| |. . .         ..|     . ||| ... | |.| | .|.|.|| |.||
IHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIIT

Kinase AqueK625.AA CZAK 1-77 32 1.3e-11 38.56 In-house 130-222 (279) Show / Hide
Range on Protein: 1-77
Range on HMM: 130-222/279
Sequence Identity: 32% (30 aa)

IIHRDVSSANVLLENKWK-------------TKISDFGSA---KFARAAVTEAPGAAVYSAPESIRTRKQTTKMDSYSYGVLLCEMITCHFPN
|.||| || |.||.                  ||.|||     .      | . |   . |||       | | | ||.| .| ..|||  |.
ILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEKVDVYSFGMILWCIITCDQPY

Kinase AqueK625.AA ARK 1-73 31 4.9e-10 32.94 In-house 124-211 (280) Show / Hide
Range on Protein: 1-73
Range on HMM: 124-211/280
Sequence Identity: 31% (28 aa)

IIHRDVSSANVLLENKWKTKISDFGSAKFARAAVTEAP----GAAVYSAPESIR-----------TRKQTTKMDSYSYGVLLCEMITC
|.|||. | | |   .|. |..||| ..|. ..  |      |  .| |||.               . ||| | || |. . ||...
IVHRDLKSLNLLVNENWTCKVCDFGLSRFNTMSNQETLGKMRGTFAYCAPEVYYFQDIDDDYVSNGKHYTTKSDVYSMGIIMWEMVYR

Kinase AqueK625.AA TKL-Unique 1-76 29 5.1e-10 31.71 In-house 133-233 (290) Show / Hide
Range on Protein: 1-76
Range on HMM: 133-233/290
Sequence Identity: 29% (30 aa)

IIHRDVSSANVLLENK-----WKTKISDFGSAKFARAAVTEAPGAA------------VYSAPESIRT--RKQTTKMDSYSYGVLLCEMITCHF------
|||||  | |.|. |.     |. ||.||| .||.    ..  .               ..||| .|    . ..| | ||.|. | |..| .       
IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKK

P
|
P

Kinase AqueK625.AA Pkinase 1-116 23 6.3e-10 36.18 Pfam 129-293 (293) Show / Hide
Range on Protein: 1-116
Range on HMM: 129-293/293
Sequence Identity: 23% (39 aa)

IIHRDVSSANVLLENKWKT----KISDFGSA----KFARAAVTEAPGAAVYSAPESIR-TRKQTTKMDSYSYGVLLCEMIT--CHFPNA-------EKFE
|||||. ..|.|. |.  .    ||.|||.|           |   |   | ||| ||  .. ..| | .|.|..| ||..    ||..       ... 
IIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQM

TVKVSS-------------------------------PQLYELIVLCINEEPDKRPTMSEIILK--L
 ... .                               . . ..|  |..  | ||||  .|     .
ICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase AqueK625.AA Dicty4-Unclassified 1-72 32 6.6e-09 26.61 In-house 130-203 (263) Show / Hide
Range on Protein: 1-72
Range on HMM: 130-203/263
Sequence Identity: 32% (24 aa)

IIHRDVSSANVLLENKWKTKISDFGSAKFA--RAAVTEAPGAAVYSAPESIRTRKQTTKMDSYSYGVLLCEMIT
.||||. |.|.|.      || ||| .         |   |     .||  .    . | | |||...| |..|
FIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELAT

Kinase AqueK625.AA TK-Unique 1-72 34 9.7e-09 26.39 In-house 154-234 (294) Show / Hide
Range on Protein: 1-72
Range on HMM: 154-234/294
Sequence Identity: 34% (28 aa)

IIHRDVSSANVLLENKWKTKISDFGSAK------FARAAVTEAPGAAVYSAPESIR--TRKQ-TTKMDSYSYGVLLCEMIT
|.|||... |||| .. . ||.||| |.            .. .    . ||||..  ..   ||| | .|.|||. |. |
IVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT

Kinase AqueK625.AA Dicty4-Unclassified 94-116 52 1.9e-08 24.98 In-house 241-263 (263) Show / Hide
Range on Protein: 94-116
Range on HMM: 241-263/263
Sequence Identity: 52% (12 aa)

LIVLCINEEPDKRPTMSEIILKL
||. |  ..| ||||| .|| .|
LIKWCWHNDPNKRPTMNQIIQYL

Kinase AqueK625.AA Pkinase_Tyr 88-116 37 5.8e-08 27.58 Pfam 242-270 (270) Show / Hide
Range on Protein: 88-116
Range on HMM: 242-270/270
Sequence Identity: 37% (11 aa)

SPQLYELIVLCINEEPDKRPTMSEIILKL
.. .|.|. .| ...|..|||.|||. .|
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase AqueK625.AA TK-Unique 85-116 31 9.8e-08 22.88 In-house 263-294 (294) Show / Hide
Range on Protein: 85-116
Range on HMM: 263-294/294
Sequence Identity: 31% (10 aa)

KVSSPQLYELIVLCINEEPDKRPTMSEIILKL
...|...|.|.  |...||..||. ..|. .|
HCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase AqueK625.AA TKL-Unique 89-116 35 2e-06 19.0 In-house 263-290 (290) Show / Hide
Range on Protein: 89-116
Range on HMM: 263-290/290
Sequence Identity: 35% (10 aa)

PQLYELIVLCINEEPDKRPTMSEIILKL
... .||  | . .|..||. .||| .|
KEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase AqueK625.AA MLK 93-116 37 5e-06 17.15 In-house 268-291 (291) Show / Hide
Range on Protein: 93-116
Range on HMM: 268-291/291
Sequence Identity: 37% (9 aa)

ELIVLCINEEPDKRPTMSEIILKL
.|.  | |..| |||....|. .|
KLMKQCWNQDPHKRPSFRQIVQHL

Kinase AqueK625.AA ARK 89-115 40 5e-05 14.53 In-house 254-280 (280) Show / Hide
Range on Protein: 89-115
Range on HMM: 254-280/280
Sequence Identity: 40% (11 aa)

PQLYELIVLCINEEPDKRPTMSEIILK
.||  ||  | ...||.||.  ||.  
EQLKNLIQCCWDQDPDNRPSCEEIMEE

Kinase AqueK625.AA CZAK 91-116 46 0.00036 11.22 In-house 254-279 (279) Show / Hide
Range on Protein: 91-116
Range on HMM: 254-279/279
Sequence Identity: 46% (12 aa)

LYELIVLCINEEPDKRPTMSEIILKL
| |||  | |  || ||. ..|.  |
LGELIEMCWNKNPDERPSFKQILQHL

Kinase AqueK625.AA Pkinase_Tyr 1-25 46 0.000429 14.49 Pfam 132-156 (270) Show / Hide
Range on Protein: 1-25
Range on HMM: 132-156/270
Sequence Identity: 46% (12 aa)

IIHRDVSSANVLLE-NKWKTKISDFG
.||||.   |.|.. |. . ||.|||
CIHRDLAARNCLVTENN-VVKICDFG

Kinase AqueK625.AA Pkinase_Tyr 45-72 53 0.001716 12.45 Pfam 182-209 (270) Show / Hide
Range on Protein: 45-72
Range on HMM: 182-209/270
Sequence Identity: 53% (15 aa)

APESIRTRKQTTKMDSYSYGVLLCEMIT
|||.|...| ||| | .|.|||. |..|
APECINYGKFTTKSDVWSFGVLMWEIFT

Kinase AqueK625.AA Frk 89-117 41 0.013328 4.43 In-house 229-257 (260) Show / Hide
Range on Protein: 89-117
Range on HMM: 229-257/260
Sequence Identity: 41% (12 aa)

PQLYELIVLCINEEPDKRPTMSEIILKLD
.||||..  | ...|.||||   .  ||.
QQLYEIMLECWHSDPMKRPTFETLQWKLE