Gene AqueK624 (A.queenslandica)
AqueK624
Species: A.queenslandica
Alias: AqueK624
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK624.AA | Protein | None | 908 | None | Fasta, JSON |
| AqueK624.kin_dom | Protein Kinase Domain | None | 78 | None | Fasta, JSON |
Protein domains of AqueK624.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kelch_2 | AqueK624.AA | Kelch_2 | 16-68 | 18 | 0.007057 | 15.06 | Pfam | 5-51 (51) | Show / Hide |
Range on Protein: 16-68 Range on HMM: 5-51/51 Sequence Identity: 18% (10 aa) HSTVRVGDYLYMWGGYQPDLPTVHNNEKKKSMCSVMEVCHLRTGRWEQKPTTG |... .|. .|..||| .. . . .... .....| ||. | . HASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP |
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| Kelch_1 | AqueK624.AA | Kelch_1 | 12-68 | 14 | 13.8393 | 2.28 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 12-68
Range on HMM: 1-45/45
Sequence Identity: 14% (8 aa)
EKKEHSTVRVGDYLYMWGGYQPDLPTVHNNEKKKSMCSVMEVCHLRTGRWEQKPTTG
|. . .....| ||. . . . |. ...|..|.. |. .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP
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| Kelch_1 | AqueK624.AA | Kelch_1 | 73-120 | 20 | 1.3e-05 | 23.89 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 73-120 Range on HMM: 1-45/45 Sequence Identity: 20% (10 aa) GVMGYAAAAIGREIFYFGGWCYQGDCYHNSLYSFNVDTFNWKELSPTT |....... .|. .||.. | || ......| |....| . PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP |
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| Kelch_2 | AqueK624.AA | Kelch_2 | 73-120 | 19 | 0.001309 | 17.84 | Pfam | 1-51 (51) | Show / Hide |
Range on Protein: 73-120 Range on HMM: 1-51/51 Sequence Identity: 19% (10 aa) GVMGYAAAAIGREIFYFGGW---CYQGDCYHNSLYSFNVDTFNWKELSPTT . .. |.. .| |. |||. . .||...... .. .| |..... PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP |
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| Kelch_2 | AqueK624.AA | Kelch_2 | 129-193 | 9 | 4.244703 | 4.5 | Pfam | 1-51 (51) | Show / Hide |
Range on Protein: 129-193 Range on HMM: 1-51/51 Sequence Identity: 9% (6 aa) SLCDMIAIKVNGEDYLVVIGGKGPSSNNTPPQPGAQYSGRVQQRCNEIHFYKLSTGQWISPTVTG ... .... . .. ..|.|| .... ... |... ..| .| .. . PRYCHASCVP--GGKIYVFGGYC------------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP |
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| Kelch_2 | AqueK624.AA | Kelch_2 | 254-299 | 23 | 0.004294 | 15.88 | Pfam | 1-51 (51) | Show / Hide |
Range on Protein: 254-299 Range on HMM: 1-51/51 Sequence Identity: 23% (13 aa) GRNAHSSVLINTSSGPHLLVVGGY---------GAYDLWIFDINNKSWKKLDNLP .| |.|. . | ..|.||| |.|..| . ..|... .| PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP |
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| Kelch_1 | AqueK624.AA | Kelch_1 | 265-299 | 15 | 0.020174 | 12.45 | Pfam | 8-45 (45) | Show / Hide |
Range on Protein: 265-299 Range on HMM: 8-45/45 Sequence Identity: 15% (6 aa) TSSGPHLLVVGGYG---AYDLWIFDINNKSWKKLDNLP .. . .. |.||. . ...| ...|... ..| CVHNGKIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP |
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| Kelch_2 | AqueK624.AA | Kelch_2 | 305-350 | 23 | 5.376143 | 4.11 | Pfam | 1-32 (51) | Show / Hide |
Range on Protein: 305-350 Range on HMM: 1-32/51 Sequence Identity: 23% (11 aa) RWFHSLSVGSVTPTTNWIIVFGGSSSYSDTAVIEFRYTSNNDWSTS ......|. . ..|.||||.. |.| |||.... PRYCHASCVP----GGKIYVFGGYC----------RHTHNNDCWSM |
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| Kinase | AqueK624.AA | TKL | 516-598 | 20 | 8.1e-15 | 49.8 | In-house | 158-288 (364) | Show / Hide |
Range on Protein: 516-598
Range on HMM: 158-288/364
Sequence Identity: 20% (27 aa)
PHPILHRDVSSANVLLQ-----------PMIGVWRAKVSDYGSANLQHSI---------------------IRSVNPGGPLYAAPEAANPR---------
. ||.||| |.|.|. . . |..|..|.| . . .. | | . |||. .
KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGI
-------EHSPSMDVFSYGVLLLEMITQRIP
| |...||.|.|..| |..| ..|
DEFCKGFEYSEKCDVYSFGIVLWEILTRCRP
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| Kinase | AqueK624.AA | LRRK | 518-598 | 26 | 2.3e-09 | 29.28 | In-house | 186-282 (351) | Show / Hide |
Range on Protein: 518-598 Range on HMM: 186-282/351 Sequence Identity: 26% (26 aa) PILHRDVSSANVLLQPMI---------GVWRAKVSDYGSAN----LQHS-IIRSVNPGGPLYAAPEAANPR---EHSPSMDVFSYGVLLLEMITQR-IP ||.||| | |.||. . ||..|.| .... . ..| . |.. ||| . | . |..|.|..| | .| . .| PIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGN--PGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP |
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| Kinase | AqueK624.AA | TKL-Unique | 518-598 | 28 | 6.9e-09 | 27.66 | In-house | 132-233 (290) | Show / Hide |
Range on Protein: 518-598 Range on HMM: 132-233/290 Sequence Identity: 28% (29 aa) PILHRDVSSANVLLQPM--IGVWRAKVSDYGSANLQHSIIRSVNP-----------GGPLYAAPEAANP--REHSPSMDVFSYGVLLLEMITQRI----- ||.||| | |.|. | |..|..| | . .. .|... | | ....||| . | . ||.|.|. | |..| | PIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYK -P | KP |
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| Kinase | AqueK624.AA | MLK | 516-598 | 31 | 8.3e-09 | 26.81 | In-house | 145-235 (291) | Show / Hide |
Range on Protein: 516-598 Range on HMM: 145-235/291 Sequence Identity: 31% (29 aa) PHPILHRDVSSANVLLQP---MIGVWRAKVSDYGSANLQHSI-I-RSVNPGGPLYAAPEA---ANPREHSPSMDVFSYGVLLLEMITQRIP |.|| ||| | |.|. .. .|..| | . |.. . |.| . . |||. . | . ||.|.||.| ||.| ..| PKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP |
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| Kinase | AqueK624.AA | STE | 517-602 | 24 | 1.9e-08 | 26.08 | In-house | 171-271 (359) | Show / Hide |
Range on Protein: 517-602 Range on HMM: 171-271/359 Sequence Identity: 24% (27 aa) HPILHRDVSSANVLLQPMIGVWRAKVSDYGSAN-LQHSII-----------------RSVNPGGPLYAAPEAANP------REHSPSMDVFSYGVLLLEM | | |||. .||.|| .| .| | . |..|. | | | . ||| .. ... . |. | | ...|| HHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM ITQRIPLPEE .| . |. .. ATGKPPWHDM |
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| Kinase | AqueK624.AA | STE-Unique | 518-595 | 17 | 2.6e-08 | 25.02 | In-house | 425-549 (616) | Show / Hide |
Range on Protein: 518-595
Range on HMM: 425-549/616
Sequence Identity: 17% (22 aa)
PILHRDVSSANVLLQP--MIGVWRAKVSDYGSANLQHSI----------------------------------------IRSVNPGGPLYAAPEAANPR-
||.|||. ..|... | ..|..|.| |. . .. ..| | | .|| | |
PIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRN
----EHSPSMDVFSYGVLLLEMITQ
... |..| | ....|...
QINNPYDTKVDIWSLGCMCFHMCCG
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| Kinase | AqueK624.AA | TK | 519-594 | 19 | 3.2e-08 | 22.85 | In-house | 261-389 (486) | Show / Hide |
Range on Protein: 519-594
Range on HMM: 261-389/486
Sequence Identity: 19% (25 aa)
ILHRDVSSANVLLQ-PMIGVWR-------AKVSDYGSAN-----LQHSI------IRSVNPGGPL-------------------------YAAPEAAN--
. |||. |.|. .. | .|..|.| . | | |. ..|... . |||. |
FVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDR
-------PREHSPSMDVFSYGVLLLEMIT
. ... ||.|.|||. |. |
VFSEAEKYGKFTTKSDVWSFGVLMWEIFT
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| Kinase | AqueK624.AA | Dicty5 | 519-598 | 30 | 5.4e-08 | 23.61 | In-house | 125-202 (260) | Show / Hide |
Range on Protein: 519-598 Range on HMM: 125-202/260 Sequence Identity: 30% (25 aa) ILHRDVSSANVLLQPMIGVWRAKVSDYG-SANLQHSIIRSVNPGGPLYAAPEAANPREHSPSMDVFSYGVLLLEMITQRIP | |||. | |.|. | .|. |.| | . .. | . . |.| | . ||.|.|. | ||.|. | IIHRDLKSMNFLITEN---WKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEP |
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| Kinase | AqueK624.AA | Ciliate-E2 | 518-598 | 20 | 1.2e-07 | 22.28 | In-house | 181-295 (365) | Show / Hide |
Range on Protein: 518-598 Range on HMM: 181-295/365 Sequence Identity: 20% (25 aa) PILHRDVSSANVLLQPMIGVWRAKVSDYGSAN-----------LQHSIIRSVNP-----------------------GGPLYAAPEAANPRE-------- .|.||| |.|. |..| | . .|.. . | | | ||| | . NIIHRDIKPENILF--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQK -HSPSMDVFSYGVLLLEMITQRIP .. . |..| ||.| ||.. . | GYDYKCDIWSLGVILYEMLFGKPP |
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| Kinase | AqueK624.AA | Pkinase | 517-625 | 25 | 7.9e-07 | 25.22 | Pfam | 127-236 (293) | Show / Hide |
Range on Protein: 517-625 Range on HMM: 127-236/293 Sequence Identity: 25% (29 aa) HPILHRDVSSANVLLQ--PMIGVWRAKVSDYGSAN---LQHSIIRSVNPGGPLYAAPEAAN-PREHSPSMDVFSYGVLLLEMITQRIPLPEERVGLIDVL . |.|||. ..|.|. . |. . |..| |.| . .. .. | | |.||| . ....|. |..|.|..| ||.. | | |.. . .. . MGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-H KQSFKYDVIIRALPP | .... | .. .. DQMQMICRIMGPPLH |
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| S_TKc | AqueK624.AA | S_TKc | 380-755 | 11 | 4e-06 | -87.29 | SMART | 1-220 (231) | Show / Hide |
Range on Protein: 380-755
Range on HMM: 1-220/231
Sequence Identity: 11% (46 aa)
REIDRLI------RVLQERERELEEERREKEQVRNRLQQQLQGREQQLQQAQQQGQEREREIQQAREQVQDLQRQLQERERQLHQAEQQLQSREREAQER
|| |.| .| . |... .. |. . .||.|... .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------------------EHIRREIQILKK-------------H
EQQLQRQVEGGQQREQDLQRQLQQAQQ---QLRERDRQER-------ESSWV----------------PHPILHRDVSSANVLLQPMIGVWRAKVSDYGS
. . . | ..| . . . |... .. . . . | |.|||. .|.|| . |..| |.
HPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGL
ANLQHSIIRSVNPGGPLYAAPEAANPREHSP-SMDVFSYGVLLLEMITQRIPLPEERVGLIDVLKQSFKYDVIIRALPPNKMAAKAAPDYQPVERSGHST
| . . | | | ||| ... . |. | |..| ||.. . | | . ......
ARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------------------------------
VRTTSKNMRAHKPKAVLGLNLKGVSLYDERSKSITRVPVDKVTYVTHDPEDQCYFGVIIQTKESHTGFRLYCFKAKRPIAVTFVNSSLELFDLIMKLRQA
| |. |.|.|. |
--------------------------------------------------------------------------------------SPEAKDFIRKCLQK
KKK----MKEEKE
. | .
DPEKRPTA-EALQ
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| Kinase | AqueK624.AA | CZAK | 514-546 | 37 | 9e-06 | 17.1 | In-house | 125-167 (279) | Show / Hide |
Range on Protein: 514-546 Range on HMM: 125-167/279 Sequence Identity: 37% (16 aa) WVPHPILHRDVSSANVLLQPMIG----------VWRAKVSDYG | | |||||| || |.|| . .|..|.| WKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFG |
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| Kinase | AqueK624.AA | PTB | 580-750 | 15 | 0.000136 | 14.8 | SMART | 1-156 (156) | Show / Hide |
Range on Protein: 580-750 Range on HMM: 1-156/156 Sequence Identity: 15% (29 aa) MDVFSYGVLLL---EMITQR-IPLPEERVGLIDVLKQSFKYDVIIRALPPNKMAAKAAPDYQPVERSGHSTVRTTSKNMRAHKPKAVLGLNLKGVSLYDE .. .. |. | |. | ..|. .. ... . . .. .. |. | .| . .||.| |. PWGCCFNVWYLGCVEVPHHRNSMAPGKGMQVCQECMRKIR-------------------------------------QHWKHWQKMHLHISVDGVKLIDP RSK-SITRVPVDKVTYVTHDP-----------EDQCYFGVIIQTKESH------TGFRLYCFKAKRPIAVTFVNSSLELFDLIMKLRQAKKKM .| | . |. ..... ||| .| ..||.|. . .. . ||...|. . | | . . ...|.......|.... QTKQVIHHHPIHRISFCAHDPYRWNTGGHHCCDDDRCFGYICRHPNDRGSHRMTYWFRCHVFWCEDPHAEDIAQTIGQAFQVCYQQCQKQRCQ |
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| Kinase | AqueK624.AA | CZAK | 565-598 | 32 | 0.012478 | 5.56 | In-house | 188-221 (279) | Show / Hide |
Range on Protein: 565-598 Range on HMM: 188-221/279 Sequence Identity: 32% (11 aa) YAAPEAANPREHSPSMDVFSYGVLLLEMITQRIP . ||| .. ||.|.| .| ..|| . | WMAPECFKGENYTEKVDVYSFGMILWCIITCDQP |
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