Gene AqueK594 (A.queenslandica)
AqueK594
Species: A.queenslandica
Alias: AqueK594
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
AqueK594.AA | Protein | None | 305 | None | Fasta, JSON |
AqueK594.kin_dom | Protein Kinase Domain | None | 196 | None | Fasta, JSON |
Protein domains of AqueK594.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | AqueK594.AA | TKL | 62-296 | 20 | 1.2e-48 | 167.98 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 62-296 Range on HMM: 1-364/364 Sequence Identity: 20% (74 aa) LGRGSYGVVMVGIFRG----------LKVAVKYLHPVIASYYNE-------------------------ERFIREMKMASLLRHPNLVQFIGATLGDN-- .|.|..|.| |..|| |||| .. . .. .....|..| | |||||.|||.|. . . IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG ------------PLILTERM-TTS-LYYEKKNVQLARPSILSIAIQVALGLNYLHLQKP-----NALIHRDVSSPNILLDNIGP----------AKYRAK . | .| . | |.| . ....|...|.|.|||| ..| ..|||| |.|||.|. . | ...| CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK VSDYGSFAMAVDS----------------------QTERPGSIAYSAPEAFNPN----------------EHTPAMDVYSFCVLLIEMIINKAPETTVKE ..|.| . | . |.... |||... . | ....||||| ..| |.. . |. .. ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY RREQ---------ALKI----------------------AGWTVMKNLVQRGINEKKEFRPKMAEIIKEL . .. .. . .. ||.| |. ... | || . ||.|.| MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | AqueK594.AA | MLK | 56-246 | 26 | 7.9e-31 | 104.24 | In-house | 1-230 (291) | Show / Hide |
Range on Protein: 56-246 Range on HMM: 1-230/291 Sequence Identity: 26% (61 aa) VITDEELGRGSYGVVMVGIFRGLK-----VAVKYLHPVI----ASYYNEERFIREMKMASLLRHPN----LVQFIGATLGD-N-PLILTERMTT-SLY-- . | .| ||.|.| | .|. |||| . | .| . | .| . .. |.||| .|| |. | . . .|..| . ||| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV -YEKKN------------VQLARPSILSIAIQVALGLNYLHLQKPNALIHRDVSSPNILLDN----IGPAKYRAKVSDYGSFAMAVDS---QTERPGSIA ..... . .....| |.| |..||| ..| ..|||| |.|||.|. . .. .|..| | . . .. . ..|. | LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDM--HHGTLKICDFGTSRDWHQMCTNMMSNAGTYA YSAPEAF---NPNEHTPAMDVYSFCVLLIEMI . |||.. . . . ||.|. |.| ||. WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEML |
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Kinase | AqueK594.AA | TK | 56-245 | 17 | 2.1e-28 | 91.72 | In-house | 1-387 (486) | Show / Hide |
Range on Protein: 56-245 Range on HMM: 1-387/486 Sequence Identity: 17% (67 aa) VITDEELGRGSYG---VVMVGIFRGL---------------------------KVAVKYLHPVIASYYNEER---------------FIREMKMAS--LL .. ..||.| .| .|. |. ||. .|||| |.. |. .|.. . .|||| . |. ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG RHPNLVQFIG-ATLGDN------------PLILTERMTT------SLYYEKKNV---------------------------------------------- .|||.|...| | |.. ..|..| | . | .|. HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY ------------------------------QLARPSILSIAIQVALGLNYLHLQKPNAL----IHRDVSSPNILLDNIGPAK-------YRAKVSDYG-S || . | .. |.| |. ||| .. . .|||. |.|... .. | . .|..|.| | DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS ------FAMAVDS------------------------------QTERPGSIAYSAPEAFN---------PNEHTPAMDVYSFCVLLIEM | ...| |. . | . |||..| . .|.. ||.|| ||. |. RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI |
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Kinase | AqueK594.AA | CZAK | 59-246 | 31 | 1.6e-24 | 86.04 | In-house | 4-216 (279) | Show / Hide |
Range on Protein: 59-246 Range on HMM: 4-216/279 Sequence Identity: 31% (68 aa) DEELGRGSYGVVMVGIFRGLKVAVKYLHPVIASYYNE----ERFIREMKMASLLRHPNLVQFIGA-TLGD--NPLILTERMT----TSLYYEKKNVQLAR . |.| .| | . || ||.| .| | . | .| | |.||| |||.|| ... | .| | | .. . . GQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYHKQN PSI-LSIAIQVALGLNYLHL-QKPNALIHRDVSSPNILLD-NIG--------PAKYRAKVSDYG-S-FAMAVDSQ-TERPGSIAYSAPEAFNPNEHTPAM |.. ...|| .| | |||| ||| .||| || ||||| .. .|..|.| | | .. | |.... ||| | |. PHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEKV DVYSFCVLLIEMI ||||| .| ..| DVYSFGMILWCII |
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Kinase | AqueK594.AA | Pkinase | 56-251 | 22 | 7.6e-23 | 81.85 | Pfam | 1-211 (293) | Show / Hide |
Range on Protein: 56-251 Range on HMM: 1-211/293 Sequence Identity: 22% (50 aa) VITDEELGRGSYGVVMVGIFRGLK--VAVKYLHPVIASYYNEERFIR--EMKMASLLRHPNLVQFIGATL-GDNPLILTERMTT-----SLY------YE . . .|.||.|.| .. .| |||| . . .. ... .| | .. |.||| |..... .|.. . .| . .|. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KKNVQLARPSILSIAIQVALGLNYLHLQKPNALIHRDVSSPNILLDNIGPAKYRA----KVSDYGS--F--AMAVDSQTERPGSIAYSAPEAFN-PNEHT .. . . ... |.. ||.|.| . ||||. . |||.|| .. |..| |. . | . |.. | ||| . .... GCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDN----NGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG PAMDVYSFCVLLIEMIINKAP |. |..|. ..|.||. . | PKVDMWSCGCILYEMLCGRPP |
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Kinase | AqueK594.AA | S_TKc | 56-299 | 20 | 2.3e-22 | 81.53 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 56-299 Range on HMM: 1-231/231 Sequence Identity: 20% (55 aa) VITDEELGRGSYGVVMVGIFRG--LKVAVKYLHPVIASYYNEERFIREMKMASLLRHPNLVQFIGATLGDNPLILTERMTT---SLYYEKKNVQ------ ...|.|..|.|. .. .. .||.| .. |...||... . .|||.|..... |. . .| . . .|. |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -LARPSILSIAIQVALGLNYLHLQKPNALIHRDVSSPNILLDNIGPAKYRAKVSDYGSFAMAVDSQTERPGSIAYSAPEAFNPNEHTP-AMDVYSFCVLL . . ... |....|.|.| .. ||||. |||||. . |..| | .| . | |. | ||| . ... . |..|. ..| PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE------HIKICDFG-LARQL---TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL IEMIINKAPETTVKERREQALKIAGWTVMKNLVQRGINEKKEFRPKMAEIIK-E-----LKQM .||. . | .. .|. | .|..... . | || |. . | . YEMLCGYPPFP----QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | AqueK594.AA | Dicty4 | 56-245 | 29 | 5.4e-22 | 70.29 | In-house | 1-210 (277) | Show / Hide |
Range on Protein: 56-245 Range on HMM: 1-210/277 Sequence Identity: 29% (64 aa) VITDEELGRGSYGVVMVGIFRGLKVAVKYL--HPVIASYYNEERFIREMKMASLLRHPNLVQFIGATL--GDNP---LILTERM-TTSLYY--EK----- .....|.||.| | |. || .|||| | | . .. . . | .| . . .||||...| || . .| .| || | ..|| . INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ -KNVQLARPSILS---IAIQVALGLNYLHLQKPNALIHRDVSSPNILLDNIGPAKYRAKVSDYGSFAM---AVDSQTE----RPGSIAYSAPEAFNPNEH ....| | |.. .|. .|.|.|.|| |. |||| | |.| | . .|.||.| | .. . ... |. .. ||| .. QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD----KNWRVKVCDFG-LSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPY TPAMDVYSFCVLLIEM . . ||||| .| |. NEKADVYSFGIVLWEI |
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Kinase | AqueK594.AA | STE | 57-246 | 18 | 6.6e-20 | 67.06 | In-house | 1-262 (359) | Show / Hide |
Range on Protein: 57-246 Range on HMM: 1-262/359 Sequence Identity: 18% (51 aa) ITD-EELGRGSYGVVMVGIFR-----------------GLKVAVKYLHPVIAS---------------YYNEERFIREMKMASLLR--HPNLVQFIGATL .. |..|.|..|.| .. . | .|.| .. . .......|.|. . .. ||| |...|. . WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF --------GDNPLILTERMT----TSLYYEKKNVQLA------------RPSILSIAIQVALG-LNYLHLQKPNALIHRDVSSPNILLDNIGPAKYRAKV .|. | | | .... .|. .. . | |. |. | |.||| .. ||||. . |||| .| KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL---------VKL SDYGSFAMAVDSQT----------------ER---PGSIAYSAPEAFNP------NEHTPAMDVYSFCVLLIEMI .| | . .|| . .| |. . ||| .. .... |..|. ..|||. CDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA |
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Kinase | AqueK594.AA | Pkinase_Tyr | 56-246 | 27 | 9.2e-20 | 67.56 | Pfam | 1-208 (270) | Show / Hide |
Range on Protein: 56-246 Range on HMM: 1-208/270 Sequence Identity: 27% (60 aa) VITDEELGRGSYGVVMVGIFR------GLKVAVKYLHPVIASYYN--EERFIREMKMASLL-RHPNLVQFIGATL--GDN--PLILTERMTT---SLYYE .. ...||.|..|.|. |. . ...|||| | . |. . | |.||.|. . | .|||.|...|. . |. ..| .| | | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR KK---NVQLARPSILSIAIQVALGLNYLHLQKPNALIHRDVSSPNILLDNIGPAKYRAKVSDYGSFAMAVDS---------QTERPGSIAYSAPEAFNPN |. . .| . .|....|.| |..||. .. .||||. |.|... . .|..| | .| | ... . | |||..| . KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE----NNVVKICD---FGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYG EHTPAMDVYSFCVLLIEMI . | . ||.|| ||. |.. KFTTKSDVWSFGVLMWEIF |
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Kinase | AqueK594.AA | DRK | 56-200 | 33 | 1.5e-18 | 59.52 | In-house | 1-145 (258) | Show / Hide |
Range on Protein: 56-200 Range on HMM: 1-145/258 Sequence Identity: 33% (52 aa) VITDEELGRGSYGVVMVGIFRGLKVAVKYLHPVIASYYNEERFI----REMKMASLLRHPNLVQFIGA-TLGDNPLILTERMTT-SLYY--EKKNVQLAR . |||.|| | | || .|||| | . |.| |. || . . ||||| .||.|. . ..| .| | ||| ... IKIGNRIGRGNYGEVFRGTWRGTQVAVKML---FNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDW PSILSIAIQVALGLNYLHLQKPNALIHRDVSSPNILLDNIGPAKYRAKVSDYG | ...... .| |..||| | |||| | | | | .. ||.|.| PLMKQMMFDCAKGMIYLHCCNP-IIIHRDLKSHNLLVDE----HWQVKVADFG |
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Kinase | AqueK594.AA | Dicty5 | 56-251 | 26 | 2.4e-18 | 59.73 | In-house | 1-202 (260) | Show / Hide |
Range on Protein: 56-251 Range on HMM: 1-202/260 Sequence Identity: 26% (55 aa) VITDEELGRGSYGVVMVGIFRGLKVAVKYLHPVIASYYNEERFIREMKMASLLR--HPNLVQFIGATLGDNPL--ILTERMT----TSLYYEKKN---VQ |. . |. | | ||..| ||.| . . .. . | || . |. |||.. . || . ..|| .. .... VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP LARPSILSIAIQVALGLNYLHLQKPNALIHRDVSSPNILLDNIGPAKYRAKVSDYGS--FAMAVDSQTERPGSIAYSAPEAFNPNEHTPAMDVYSFCVLL .| . .|..|| .| .. .|| ||||. | |.|. . .|. |.| | . | | .. |.| || . . ||||| . | IAYFQQLHMAIDIAQSMRHLHSM---NIIHRDLKSMNFLITE----NWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVL IEMIINKAP ||. | | WEMFTRKEP |
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Kinase | AqueK594.AA | TKL-Unique | 150-251 | 28 | 7e-17 | 56.21 | In-house | 112-233 (290) | Show / Hide |
Range on Protein: 150-251 Range on HMM: 112-233/290 Sequence Identity: 28% (35 aa) ILSIAIQVALGLNYLHLQKPNALIHRDVSSPNILLDNI-GPAKYRAKVSDYGSFAMAVDSQ----TERP---------GSIAYSAPEAFNP--NEHTPAM ....||..|.|..||| .| |||| |.|.|.|| |....|..| | .. .. . .. ||. ..||| .. . . RVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFG-LSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKS DVYSFCVLLIEMIINKA------P ||||| . |.|.. .| | DVYSFGIVLWEIATRKITKTYKKP |
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Kinase | AqueK594.AA | TyrKc | 56-296 | 22 | 2.2e-15 | 26.16 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 56-296 Range on HMM: 1-280/280 Sequence Identity: 22% (67 aa) VITDEELGRGSYGVVMVGIFRGLKVAVKYLHPVIASYYNEERFIREMKMASLL--RHPNLVQFIGATLG--------DNPLILTERMT---TSLYYEKKN . ...||.| .|.|. |. . ..|||| |.. .| |.||... . | .|||.|...|. . . ..|..| | | |. ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR VQLARPSILSIAIQVALGLNYLHLQKPNALIHRDVSSPNILLDNIGPAKYRAKVSDYGSFAMAVDSQTE-----------------RP--GSIAYSAPEA .| . ||...|.| | .||| . .|||| |.|... . ..|.|| | .. | . . | |||. PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH----TVKISD---FGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC FNPNEHTPAMDVYSFCVLL-----------IE-----MIINKAPETTVKERREQALKIA-------GWTVMKNLVQRGINEKKEFRPKMAEIIKEL .| .. |.. ||.|| |.. . | . | . .| . . . | .. .. .|. | || ..||.... INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | AqueK594.AA | HH498 | 148-245 | 33 | 2.6e-13 | 38.15 | In-house | 121-219 (284) | Show / Hide |
Range on Protein: 148-245 Range on HMM: 121-219/284 Sequence Identity: 33% (35 aa) PSILSIAIQVALGLNYLHLQKPNALIHRDVSSPNILLDNIGPAKYRAKVSDYGS--FAMAVDSQ--TERPGSIAYSAPEAFN-PNEHTPAMDVYSFCVLL .|.. |.. || | |||| . |||| | |||.. | .|.| |.| | .. | || . ||| | . ||.|. . QSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDG----HAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCI IEM || WEM |
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Kinase | AqueK594.AA | TKL-Unique | 60-130 | 32 | 4.8e-13 | 42.52 | In-house | 3-80 (290) | Show / Hide |
Range on Protein: 60-130 Range on HMM: 3-80/290 Sequence Identity: 32% (26 aa) EELGRGSYGVVMVGIFRGLKVAVKYLHPVIASYYNE--ERFIREMKMASLLR-HPNLVQFIGATLG---DNP--LILTE . .|.|.||.| |..|| .||.| .|| .. || . |..| . . |. |||.|...|.. ..| | .| NKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVME |
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Kinase | AqueK594.AA | HH498 | 56-123 | 32 | 3e-08 | 21.83 | In-house | 1-74 (284) | Show / Hide |
Range on Protein: 56-123 Range on HMM: 1-74/284 Sequence Identity: 32% (24 aa) VITDEELGRGSYGVVMVGIFRGLKVAVK-YLHPVIASYYN-----EERFIREMKMASLLRHPNLVQFIGATLGD . . | | ||.| | | .|. |||| | . . .|.|| . . | ||. |||..|.. | IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDD |
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Kinase | AqueK594.AA | MLK | 271-296 | 26 | 6e-05 | 13.24 | In-house | 266-291 (291) | Show / Hide |
Range on Protein: 271-296 Range on HMM: 266-291/291 Sequence Identity: 26% (7 aa) MKNLVQRGINEKKEFRPKMAEIIKEL .|.| .. |.. . ||....|...| WKKLMKQCWNQDPHKRPSFRQIVQHL |
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Kinase | AqueK594.AA | HH498 | 273-296 | 33 | 0.11186 | 0.64 | In-house | 261-284 (284) | Show / Hide |
Range on Protein: 273-296 Range on HMM: 261-284/284 Sequence Identity: 33% (8 aa) NLVQRGINEKKEFRPKMAEIIKEL ||.|.. . | || ..|. | NLIQMCWHPCPENRPDFDQIVTIL |
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Kinase | AqueK594.AA | Pkinase_Tyr | 280-296 | 35 | 1.528161 | 2.46 | Pfam | 254-270 (270) | Show / Hide |
Range on Protein: 280-296 Range on HMM: 254-270/270 Sequence Identity: 35% (6 aa) NEKKEFRPKMAEIIKEL ... | || ..||. .| HYDPEDRPTFSEIHEQL |