AqueK576

Species: A.queenslandica
Alias: AqueK576
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK576.AA Protein None 143 None Fasta, JSON
AqueK576.kin_dom Protein Kinase Domain None 118 None Fasta, JSON

Protein domain

Protein domains of AqueK576.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK576.AA TKL 6-130 14 7.9e-17 57.13 In-house 162-364 (364) Show / Hide
Range on Protein: 6-130
Range on HMM: 162-364/364
Sequence Identity: 14% (30 aa)

VHEDVSSPNVLLKPCTG---------AAGYEAKLADYGTAKLQQGTG---------------------STVMPGNPAYAAPEAHDPD-------------
.| |  |.|.|..             .| . .|..|.|...  ...|                     .    |.|.. |||. . .             
IHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFC

---QHSPAMDVYSYSVLLTEMTLCSPPEMMTAEREVQ---------SGSV-----------------------SWSDMKSLIQRGLNANPRARPTMAQVI
   . |...||||. ..| |.  . .|.    .....         .. .                        . .||.|.|.  ...|..||.. ...
KGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEIL

ESC
.  
KRL

Kinase AqueK576.AA MLK 6-80 30 2e-06 18.56 In-house 149-229 (291) Show / Hide
Range on Protein: 6-80
Range on HMM: 149-229/291
Sequence Identity: 30% (25 aa)

VHEDVSSPNVLLKP-CTGAAGYEAKLADYGTAK-LQQG-TGSTVMPGNPAYAAPEA---HDPDQHSPAMDVYSYSVLLTEM
.| |  |.|.|.   |   ..  .| .| ||.. ..|  |  . ..|..|. |||.      .. | . ||.|. |.| ||
IHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEM

Kinase AqueK576.AA MLK 105-130 26 1.6e-05 15.29 In-house 266-291 (291) Show / Hide
Range on Protein: 105-130
Range on HMM: 266-291/291
Sequence Identity: 26% (7 aa)

MKSLIQRGLNANPRARPTMAQVIESC
.|.|...  |..|. ||...|...  
WKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase AqueK576.AA TKL-Unique 7-80 25 4.6e-05 14.01 In-house 135-221 (290) Show / Hide
Range on Protein: 7-80
Range on HMM: 135-221/290
Sequence Identity: 25% (22 aa)

HEDVSSPNVLLKPCTGAAGYEAKLADYGTAKLQQ--GTGSTVMP---------GNPAYAAPEAHDP--DQHSPAMDVYSYSVLLTEM
| |  |.|.|.      | . .|..| |..|..    .... ..         |.. ..|||      .| |   ||||... | |.
HRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEI

Kinase AqueK576.AA CZAK 6-86 25 6.2e-05 14.03 In-house 131-221 (279) Show / Hide
Range on Protein: 6-86
Range on HMM: 131-221/279
Sequence Identity: 25% (23 aa)

VHEDVSSPNVLLKPCTG--------AAGYEAKLADYGTA--KLQQGTGSTVMPGNPAYAAPEAHDPDQHSPAMDVYSYSVLLTEMTLCSPP
.| | || |.||                  .| .|.|    .  |..  |   |  .. |||    .  ..  ||||.  .| ..  |  |
LHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEKVDVYSFGMILWCIITCDQP

Kinase AqueK576.AA TK 6-130 13 7.9e-05 11.29 In-house 262-486 (486) Show / Hide
Range on Protein: 6-130
Range on HMM: 262-486/486
Sequence Identity: 13% (30 aa)

VHEDVSSPNVLLKPCTGAA------GYEAKLADYGTA---------KLQQGTGSTVMPGNPA---------------------------YAAPEAHD---
|| |.   |.|.      .      |. .|.||.| .         ......  ... .  .                           . |||. .   
VHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRV

------PDQHSPAMDVYSYSVLLTEMT-LC-SPPEM-MT----------------------------------AEREVQSGSVSW------------SDM
         .... ||.|. ||. |.  ..  |.   |.                                   ...   .  .|             ..
FSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEY

KSLIQRGLNANPRARPTMAQVIESC
  |.|.  ...|. |||..|. |  
YDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK576.AA Dicty4 106-133 31 0.000104 11.83 In-house 249-277 (277) Show / Hide
Range on Protein: 106-133
Range on HMM: 249-277/277
Sequence Identity: 31% (9 aa)

KSLIQRGLNANPRARPTMAQVIES-CIEK
|.|||. .. .|  ||.....|.    | 
KHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase AqueK576.AA NAK-Unclassified 103-132 30 0.000111 11.96 In-house 376-405 (405) Show / Hide
Range on Protein: 103-132
Range on HMM: 376-405/405
Sequence Identity: 30% (9 aa)

SDMKSLIQRGLNANPRARPTMAQVIESCIE
.. ..||.  ||..|. ||.  ||..   .
NQLHNLIKIMLNEDPIQRPNIYQVLNHICQ

Kinase AqueK576.AA LZK 6-80 32 0.000308 10.1 In-house 109-180 (241) Show / Hide
Range on Protein: 6-80
Range on HMM: 109-180/241
Sequence Identity: 32% (25 aa)

VHEDVSSPNVLLKPCTGAAGYEAKLADYGTAKLQQGTGSTVM--PGNPAYAAPEAHDPDQHSPAMDVYSYSVLLTEM
.| |  |||.|      ..    | .|.|| . ..   || |   |  |  |||    .  |   |..|. | | ||
IHRDLKSPNILI-----SHNDVVKICDFGTSHMWNEMDSTKMSFCGTVAWMAPEVIRNEPCSEKVDIWSFGVVLWEM

Kinase AqueK576.AA ARK 106-129 33 0.000321 11.58 In-house 257-280 (280) Show / Hide
Range on Protein: 106-129
Range on HMM: 257-280/280
Sequence Identity: 33% (8 aa)

KSLIQRGLNANPRARPTMAQVIES
|.|||. .. .|  ||.  ...|.
KNLIQCCWDQDPDNRPSCEEIMEE

Kinase AqueK576.AA LRRK 12-77 27 0.000322 10.81 In-house 194-272 (351) Show / Hide
Range on Protein: 12-77
Range on HMM: 194-272/351
Sequence Identity: 27% (22 aa)

SPNVLL-KPCTGA------AGYEAKLADYGTAK----LQQGTGSTVMPGNPAYAAPEAHDPD---QHSPAMDVYSYSVLL
|||.|| .  ..       | . ||.||.|.      .. |  ...  ||| . |||    .   . .   |.||. ..|
SPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV-GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL

Kinase AqueK576.AA LRRK 95-132 21 0.004354 6.75 In-house 314-351 (351) Show / Hide
Range on Protein: 95-132
Range on HMM: 314-351/351
Sequence Identity: 21% (8 aa)

VQSGSVSWSDMKSLIQRGLNANPRARPTMAQVIESCIE
.. . . | ....|||   ...|. ||.. |...   .
YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase AqueK576.AA TKL-Unique 108-130 30 0.017165 4.82 In-house 268-290 (290) Show / Hide
Range on Protein: 108-130
Range on HMM: 268-290/290
Sequence Identity: 30% (7 aa)

LIQRGLNANPRARPTMAQVIESC
|||.. . .|  ||.  ..|.. 
LIQQCWHHDPSQRPSFDEIIHRL