Gene AqueK574 (A.queenslandica)
AqueK574
Species: A.queenslandica
Alias: AqueK574
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
AqueK574.AA | Protein | None | 469 | None | Fasta, JSON |
AqueK574.kin_dom | Protein Kinase Domain | None | 91 | None | Fasta, JSON |
Protein domains of AqueK574.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | AqueK574.AA | TKL | 332-416 | 23 | 3.2e-17 | 58.57 | In-house | 145-282 (364) | Show / Hide |
Range on Protein: 332-416 Range on HMM: 145-282/364 Sequence Identity: 23% (32 aa) LNYLHLFKP-----QPIIHRDVSSPNVLLKPFGP----------AGYEAKVTDYGTA-------DLQETTCTIM---------------PGNAAYAAPEA .|||| .| |||||| |.|.|.. . | . .|..|.|.. . . | |.| |. .. |||. MNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEV RDPE----------------QHSPAMDVYSYSVLLMEM . . . |...||||. ..| |. LRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEI |
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Kinase | AqueK574.AA | MLK | 332-416 | 33 | 6.3e-17 | 55.37 | In-house | 137-229 (291) | Show / Hide |
Range on Protein: 332-416 Range on HMM: 137-229/291 Sequence Identity: 33% (32 aa) LNYLHLFKPQPIIHRDVSSPNVLLK----PFGPAGYEAKVTDYGTAD-LQET-T-CTIMPGNAAYAAPEAR---DPEQHSPAMDVYSYSVLLMEM ..||| .|.|||||| |.|.|. .. .. .|..| ||. .... | . ..|..|. |||.. |. | . ||.|. |.| || MHYLHSMAPKPIIHRDLKSHNILIDEICHDM--HHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEM |
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Kinase | AqueK574.AA | Dicty4 | 265-327 | 36 | 4.7e-14 | 43.43 | In-house | 2-66 (277) | Show / Hide |
Range on Protein: 265-327 Range on HMM: 2-66/277 Sequence Identity: 36% (24 aa) VTGVELGRGSYATVNVGIFRGLRVAVKSL--HTIIISDYNLALFSREMSIASRVRHPNLVQFIGA ......|.||...| |. || |||| | | . . . | | .| .| . ||||...| || NIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGA |
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Kinase | AqueK574.AA | DRK | 265-327 | 43 | 1.6e-13 | 42.18 | In-house | 2-65 (258) | Show / Hide |
Range on Protein: 265-327 Range on HMM: 2-65/258 Sequence Identity: 43% (28 aa) VTGVELGRGSYATVNVGIFRGLRVAVKSLHTIIISDYN-LALFSREMSIASRVRHPNLVQFIGA . |. |||.|. | | || |||| | | | | | | || . .. |||| .||.|. KIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGT |
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Kinase | AqueK574.AA | CZAK | 333-416 | 31 | 3.7e-12 | 40.61 | In-house | 119-215 (279) | Show / Hide |
Range on Protein: 333-416 Range on HMM: 119-215/279 Sequence Identity: 31% (32 aa) NYLHL-FKPQPIIHRDVSSPNVLLKPFGPAGYE-------------AKVTDYGTA---DLQETTCTIMPGNAAYAAPEARDPEQHSPAMDVYSYSVLLME |||| .|| ||.||| || |.|| | .|. |.| | . | | .. ||| | .. ||||. .| . NYLHDNWKPNPILHRDLSSRNILLD----HSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEKVDVYSFGMILWC M . I |
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Kinase | AqueK574.AA | HH498 | 333-416 | 37 | 1.2e-11 | 32.82 | In-house | 135-219 (284) | Show / Hide |
Range on Protein: 333-416 Range on HMM: 135-219/284 Sequence Identity: 37% (33 aa) NYLHLFKPQPIIHRDVSSPNVLLKPFGPAGYEAKVTDYG----TADLQETTCTIMPGNAAYAAPEARD-PEQHSPAMDVYSYSVLLMEM |||| ..|||||| | |.|. .| |.| |.| |. . . | ||| . ||| . | ||.|| . || NYLHNSLKHPIIHRDLNSHNILIHEDG----HAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEM |
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Kinase | AqueK574.AA | Gdt | 270-335 | 28 | 2e-11 | 35.39 | In-house | 7-76 (289) | Show / Hide |
Range on Protein: 270-335 Range on HMM: 7-76/289 Sequence Identity: 28% (21 aa) LGRGSYATVNVGIFRGLRVAVKSLHTIIISDYN--------LALFSREMSIASRVRHPNLVQFIGATKVSLNYL .. |.. .|. ||.|.. |||| . ... | . |||.| |...|.| | ||| . ...... CSQGTFGMVYKGIWRSSQVAVK---MFKHHYVNYTKTYSQSCDEIYREMDILSKIKHQNIVSFIGCV-HFSSHH |
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Kinase | AqueK574.AA | TKL | 270-329 | 22 | 9.4e-11 | 34.95 | In-house | 1-95 (364) | Show / Hide |
Range on Protein: 270-329 Range on HMM: 1-95/364 Sequence Identity: 22% (21 aa) LGRGSYATVNVGIFRG----------LRVAVKSLHTIIISDYNL-------------------------ALFSREMSIASRVRHPNLVQFIGATK .|.|....| |..|| |||| ... . .. . .|. . || ||||.|||.|. . IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCC |
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Kinase | AqueK574.AA | LISK | 269-327 | 31 | 2.2e-10 | 29.71 | In-house | 1-64 (296) | Show / Hide |
Range on Protein: 269-327 Range on HMM: 1-64/296 Sequence Identity: 31% (20 aa) ELGRGSYATVNVGIFR--GLRVAVKSLHT---IIISDYNLALFSREMSIASRVRHPNLVQFIGA |.|.|... | | | | .|.| .|. . . .. . ||. . . |||| |||.|. EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV |
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Kinase | AqueK574.AA | S_TKc | 264-459 | 16 | 2.1e-09 | -39.11 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 264-459 Range on HMM: 1-231/231 Sequence Identity: 16% (42 aa) TVTGVELGRGSYATVNVGIFRG--LRVAVKSLHTIIISDYNLALFSREMSIASRVRHPNLVQFIGATK----------VSL------NYLHLFKP----- . ..|.|....| .. .. .||.| .. . ||..| .. .|||.|..... .. |.. .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF ----------------------QPIIHRDVSSPNVLLKPFGPAGYEAKVTDYGTADLQETTCTIMPGNAAYAAPEARDPEQHSP-AMDVYSYSVLLMEMT . |||||. |.|| . |..| | | . | . | | ||| .... . |..| ..| || PFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML LHLP---PEMTLAKREXXXXLLCQAMLLMLLLK-----LVILNDTV-------QQWM | .... |. . .. .| | . . .|. CGYPPFPQMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | AqueK574.AA | LRRK | 332-413 | 30 | 6e-09 | 27.77 | In-house | 177-272 (351) | Show / Hide |
Range on Protein: 332-413 Range on HMM: 177-272/351 Sequence Identity: 30% (30 aa) LNYLHLFKPQPIIHRDVSSPNVLLKPFG-P-------AGYEAKVTDYGTAD----LQETTCTIMPGNAAYAAPEARD---PEQHSPAMDVYSYSVLL ..||| ..| |||||| |||.||. . . | . ||. |.|. .... . || . ||| . |. . |.||. ..| MEYLHSHNP-PIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL |
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Kinase | AqueK574.AA | TKL-Unique | 266-329 | 27 | 1e-08 | 27.08 | In-house | 1-66 (290) | Show / Hide |
Range on Protein: 266-329 Range on HMM: 1-66/290 Sequence Identity: 27% (19 aa) TGVELGRGSYATVNVGIFRGLRVAVKSLHTIIISDYNLA---LFSREMSIASRVR-HPNLVQFIGATK . .|.|.|..| |..|| ||.|..| .| .. |..| .. .. . |||.|...|... FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCM |
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Kinase | AqueK574.AA | CZAK | 267-327 | 35 | 1.2e-08 | 27.74 | In-house | 4-68 (279) | Show / Hide |
Range on Protein: 267-327 Range on HMM: 4-68/279 Sequence Identity: 35% (23 aa) GVELGRGSYATVNVGIFRGLRVAVKSLHTIIISDYNL----ALFSREMSIASRVRHPNLVQFIGA | . |.| . | . || ||.| .| . . | .| || | .||| |||.|| GQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGA |
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Kinase | AqueK574.AA | TKL-Unique | 332-416 | 28 | 1.5e-08 | 26.41 | In-house | 123-221 (290) | Show / Hide |
Range on Protein: 332-416 Range on HMM: 123-221/290 Sequence Identity: 28% (28 aa) LNYLHLFKPQPIIHRDVSSPNVLLKPF-GPAGYEAKVTDYGTADLQETT---CTIMP---------GNAAYAAPEARDP--EQHSPAMDVYSYSVLLMEM ..||| .| ||||| |.|.|. . | . .|. | |.. .. . .... |.. ..||| .| | ||||... | |. MYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEI |
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Kinase | AqueK574.AA | TyrKc | 264-459 | 14 | 5.9e-08 | -93.97 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 264-459 Range on HMM: 1-280/280 Sequence Identity: 14% (41 aa) TVTGVELGRGSYATVNVGIFRGLRVAVKSLHTIIISDYNLALFSREMSIASRV--RHPNLVQFIGATKVS----------------------LNYLHLFK . | .||.| . .| |. . . ||||.|. .. | ||..| ... .|||.|...|. . ..||. . ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR P-----------------------QPIIHRDVSSPNVLLKPFGPAGYEAKVTDYGTADLQETT----------------CTIMPGNAAYAAPEARDPEQH | ...|||| |.|.. . .|..| | . . .. .. |||. . PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF SPAMDVYSYSVLLMEMT-------LH-----LPPEMTLAKREXXXXLLCQAM-----------LLMLLLKLVILN--------DTVQQWM ... ||.|. |.. |. .... ... . . . . . . | .. . . TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | AqueK574.AA | LRRK | 264-326 | 14 | 3e-06 | 18.22 | In-house | 1-124 (351) | Show / Hide |
Range on Protein: 264-326 Range on HMM: 1-124/351 Sequence Identity: 14% (18 aa) TVTGVELGRGSYA-TVNVGIFRG----------------------------LRVAVKSLHT--------------------------------IIISDYN . . ..|||... .| ...|| ||.|.... .. . . LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA LALFSREMSIASRVRHPNLVQFIG . .| .|..| |. .|||.|. .| FREFRHEVWIMSHLNHPNIVSLKG |
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Pkinase_Tyr | AqueK574.AA | Pkinase_Tyr | 264-327 | 27 | 9e-06 | 20.11 | Pfam | 1-72 (270) | Show / Hide |
Range on Protein: 264-327 Range on HMM: 1-72/270 Sequence Identity: 27% (20 aa) TVTGVELGRGSYATVNVGIFR------GLRVAVKSLHTIIISDYN--LALFSREMSIASRV-RHPNLVQFIGA . | .||.|.. .| |. . .. ||||.| .. . .. | ||..| . .|||.|...|. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGV |
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Kinase | AqueK574.AA | MLK | 264-327 | 25 | 0.000184 | 11.54 | In-house | 1-77 (291) | Show / Hide |
Range on Protein: 264-327 Range on HMM: 1-77/291 Sequence Identity: 25% (20 aa) TVTGVELGRGSYATVNVGIFRGLR-----VAVKSLHTIIISDYNLA-----LFSREMSIASRVRHPN----LVQFIGA . .| ||. | | .|. . |||| .. |. | . | .| ......||| .|| |. IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGV |
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Kinase | AqueK574.AA | Pkinase | 264-327 | 26 | 0.000301 | 16.1 | Pfam | 1-68 (293) | Show / Hide |
Range on Protein: 264-327 Range on HMM: 1-68/293 Sequence Identity: 26% (18 aa) TVTGVELGRGSYATVNVGIFRGLR--VAVKSLHTIIISDYNLALFSR--EMSIASRVRHPNLVQFIGA ..| .|.||...| .. .| . |||| . ... . | | .| |..||| |..... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDW |
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Kinase | AqueK574.AA | LISK | 343-371 | 41 | 0.000639 | 8.4 | In-house | 122-150 (296) | Show / Hide |
Range on Protein: 343-371 Range on HMM: 122-150/296 Sequence Identity: 41% (12 aa) IIHRDVSSPNVLLKPFGPAGYEAKVTDYG ||||| | |.|.. .. ....||.| | IIHRDLKSKNCLVRENDNNQWRIKVCDFG |
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Kinase | AqueK574.AA | HH498 | 306-328 | 52 | 0.000767 | 7.62 | In-house | 49-71 (284) | Show / Hide |
Range on Protein: 306-328 Range on HMM: 49-71/284 Sequence Identity: 52% (12 aa) FSREMSIASRVRHPNLVQFIGAT | || || .| ||. |||..|. FCREVSIMCRLNHPCVVQFVYAC |
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Kinase | AqueK574.AA | Pkinase | 389-422 | 37 | 0.220767 | 5.97 | Pfam | 177-211 (293) | Show / Hide |
Range on Protein: 389-422 Range on HMM: 177-211/293 Sequence Identity: 37% (13 aa) YAAPEA-RDPEQHSPAMDVYSYSVLLMEMTLHLPP |.||| |. . ..|. |..|. ..| || . || YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP |
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Kinase | AqueK574.AA | Pkinase_Tyr | 405-416 | 50 | 7.917708 | 0.04 | Pfam | 196-207 (270) | Show / Hide |
Range on Protein: 405-416 Range on HMM: 196-207/270 Sequence Identity: 50% (6 aa) DVYSYSVLLMEM ||.|. ||. |. DVWSFGVLMWEI |