Gene AqueK557 (A.queenslandica)
AqueK557
Species: A.queenslandica
Alias: AqueK557
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
AqueK557.AA | Protein | None | 567 | None | Fasta, JSON |
AqueK557.kin_dom | Protein Kinase Domain | None | 200 | None | Fasta, JSON |
Protein domains of AqueK557.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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NHL | AqueK557.AA | NHL | 4-31 | 26 | 7.5e-07 | 28.91 | Pfam | 1-30 (30) | Show / Hide |
Range on Protein: 4-31 Range on HMM: 1-30/30 Sequence Identity: 26% (8 aa) LNFPWGVAVS-DGNHFIIAE-WNGSCVTIL ...|.||.|. ...|...|. | ..| .. FCHPHGVCVDPSDGHIYVADHSNNHRVWVF |
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NHL | AqueK557.AA | NHL | 52-77 | 33 | 0.001256 | 17.38 | Pfam | 1-30 (30) | Show / Hide |
Range on Protein: 52-77 Range on HMM: 1-30/30 Sequence Identity: 33% (10 aa) FSCPCGVAIT-PDKFILVSD---KHRIQKI |..| ||... .| |.|.| ||.... FCHPHGVCVDPSDGHIYVADHSNNHRVWVF |
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NHL | AqueK557.AA | NHL | 97-125 | 46 | 2.6e-10 | 41.27 | Pfam | 1-30 (30) | Show / Hide |
Range on Protein: 97-125 Range on HMM: 1-30/30 Sequence Identity: 46% (14 aa) FNSPHGISIFPITGQVYIAD-ANNHRIQVL |..|||. . | .|..|.|| ||||..|. FCHPHGVCVDPSDGHIYVADHSNNHRVWVF |
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NHL | AqueK557.AA | NHL | 145-172 | 43 | 5.6e-12 | 47.25 | Pfam | 1-30 (30) | Show / Hide |
Range on Protein: 145-172 Range on HMM: 1-30/30 Sequence Identity: 43% (13 aa) FQSPYDIAID-NQGLVYVAD-SDNHRIQKF |..| ....| ..| .|||| |.|||...| FCHPHGVCVDPSDGHIYVADHSNNHRVWVF |
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NHL | AqueK557.AA | NHL | 198-221 | 32 | 0.019607 | 13.11 | Pfam | 7-30 (30) | Show / Hide |
Range on Protein: 198-221 Range on HMM: 7-30/30 Sequence Identity: 32% (8 aa) IAIDTAANGLVYVSE-WGNARISVF ...|. .| .||.. .| |. || VCVDP-SDGHIYVADHSNNHRVWVF |
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Kinase | AqueK557.AA | TKL | 331-562 | 19 | 4.7e-40 | 139.38 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 331-562 Range on HMM: 1-364/364 Sequence Identity: 19% (71 aa) LGKGGWGEVKVADFRG----------LKVAAKCLYEIIISPHNI-------------------------MKFSHEMNIASKICHPNLLQFIGATTEGN-- .|.|| ||| . .|| || | . . . ... .. |... |...|||..||.|. .... IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG ------------PIILTELM-PTSLRKELETGGLAYHAVLNISLDVACALNYLHLFKP-----HPILHRDISSADVLLQGTGF-----------GWRAKV . | .|.. ||. | | ....||.|...|||| .| ||.|||. |. .|. . |..|. CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI SDYGSANLQPLIG---------------------RTTNPGNPVYSAPEAANPR----------------EHSPSMDVFSYGVLLLEMITRCIPLPEER-- .|.| . | . | |.| . |||. . | |...||.|.|..| |..|||.| .. CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM ------------VGLIDGIRK--------------------ASFRSLVQRCLIVEYRHCPTMNDIITEL .. .| .. |...| |.| . . |....|. .| PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | AqueK557.AA | CZAK | 328-516 | 33 | 9.9e-23 | 79.47 | In-house | 4-217 (279) | Show / Hide |
Range on Protein: 328-516 Range on HMM: 4-217/279 Sequence Identity: 33% (72 aa) GVVLGKGGWGEVKVADFRGLKVAAKCLYEIIISPHNI----MKFSHEMNIASKICHPNLLQFIGATTEGN---PIILTELMP-TSLRKELETGGLAYHAV | . |.| |||. | || || | .. . | | | || |||| .||.|| .|.. | .| | |||. | | || GQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLL-TDHYFYHKQ -----LNISLDVACALNYLHL-FKPHPILHRDISSADVLLQGTGF----------GWRAKVSDYGSA---NLQPLIGRTTNPGNPVYSAPEAANPREHSP .|. .|.| |||| .|| |||||| || .|| .|..|.| || | | . ||| .. NPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQP-FEMTQTMGCLCWMAPECFKGENYTE SMDVFSYGVLLLEMIT ||.|.| .| ..|| KVDVYSFGMILWCIIT |
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Kinase | AqueK557.AA | TKL-Unique | 327-520 | 26 | 5.9e-22 | 74.34 | In-house | 1-233 (290) | Show / Hide |
Range on Protein: 327-520 Range on HMM: 1-233/290 Sequence Identity: 26% (62 aa) TGVVLGKGGWGEVKVADFRGLKVAAKCLYEIIISPHNI-MK-FSHEMNIASKIC-HPNLLQFIGATT-----EGNPIILTELMPT-SLRKELE------- . ..| || |.|. . .|| .|| | . . ...|. |. |. | |. .|. |||.....|... ..| .| .| .| ||.. | FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN ----TGGLAYHAVLNISLDVACALNYLHLFKPHPILHRDISSADVLLQGT--GFGWRAKVSDYGSANLQPLIGRTTNP-----------GNPVYSAPEAA | . .... .|.| ...||| .| |.|||. | .|. |..|..| | . .. | ..|| |.. ..||| NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL NP--REHSPSMDVFSYGVLLLEMITRCI------P . | . ||.|.|. | |..||.| | RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP |
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Kinase | AqueK557.AA | MLK | 325-520 | 23 | 3e-20 | 67.02 | In-house | 1-235 (291) | Show / Hide |
Range on Protein: 325-520 Range on HMM: 1-235/291 Sequence Identity: 23% (57 aa) TMTGVVLGKGGWGEVKVADFRGLK-----VAAKCLY-EIIISPHN----IMKFSHEMNIASKICHPN----LLQFIGATTE-GN-PIILTELMPT-SLRK . ..|.|. |.| . .|. || | .|. . . .| | .......||| || |. .. .. |..| .. || IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN ELETG---------------GLAYHAVLNISLDVACALNYLHLFKPHPILHRDISSADVLLQ------GTGFGWRAKVSDYGSAN-LQPL-IGRTTNPGN | .. . ..|..|..| ...||| .|.|| |||. | .|. . | .|..| | . .. .. |.|. VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHG---TLKICDFGTSRDWHQMCTNMMSNAGT PVYSAPEA---ANPREHSPSMDVFSYGVLLLEMITRCIP . . |||. . | . ||.|.||.| ||.|| .| YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP |
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S_TKc | AqueK557.AA | S_TKc | 325-567 | 20 | 3.2e-20 | 74.44 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 325-567 Range on HMM: 1-231/231 Sequence Identity: 20% (53 aa) TMTGVVLGKGGWGEVKVADFRG--LKVAAKCLYEIIISPHNIMKFSHEMNIASKICHPNLLQFIGATTEGNPIILTELMPT---SLRKELETGG------ . ..|||. |.|. . .. .|| |.. .. |..| .| |||. ..... ... . .|.... .|.. .. | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -LAYHAVLNISLDVACALNYLHLFKPHPILHRDISSADVLLQGTGFGWRAKVSDYGSANLQPLIGRTTNPGNPVYSAPEAANPREHSP-SMDVFSYGVLL . . . ..|||.|.| . |.|||. . .|| . |..| |.| . || | | | ||| ... . |. | |..| PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL LEMITRCIPLPEERVGLIDGIRKASFRSLVQRCLIVEYRHCPTMNDIIT----ELNDTIY ||.... | | . ... |. ........|| .. .. || .. . .. YEMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | AqueK557.AA | TK | 325-562 | 14 | 3.1e-18 | 57.04 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 325-562 Range on HMM: 1-486/486 Sequence Identity: 14% (72 aa) TMTGVVLGKGG---WGEVKVADFRGL---------------------------KVAAKCLYEI-IISPHNIMK-FSH----------EMNIASKIC---- | .||.| .||| . ||. .|| |.| | |. . . | |...... | ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG -HPNLLQFIGATTEGN-------------PIILTELMP-TS----LRKELETGG---------------------------------------------- |||.....|. |.| ..|..|.|| . ||. | . HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY -------------------------------LAYHAVLNISLDVACALNYLHLFKPHPI----LHRDISSADVLLQGT--------GFGWRAKVSDYGSA | | | .....||.. ||| . |||. .|. |.| .|..|.| . DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS N-----LQPLIG------RTTNPGNPV-------------------------YSAPEAAN---------PREHSPSMDVFSYGVLLLEMITRC-IPLP-- | |. |....| .. . |||. | . ... ||.|.|||. |. |.. | . RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG ---------------------------------EERVGLI--DGIRK-------------ASFRSLVQRCLIVEYRHCPTMNDIITEL ..| . .. . . | |.| . .. ||. .. .| MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | AqueK557.AA | HH498 | 420-520 | 39 | 4e-15 | 44.01 | In-house | 124-225 (284) | Show / Hide |
Range on Protein: 420-520 Range on HMM: 124-225/284 Sequence Identity: 39% (41 aa) LNISLDVACALNYLHLFKPHPILHRDISSADVLLQGTGFGWRAKVSDYG-SANLQPLIGRT-TN-PGNPVYSAPEAAN-PREHSPSMDVFSYGVLLLEMI . ||.||| |||| .||| ||| | .|. | .|.| |.| | .. . . | |||. . ||| | |||||. . || MTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDG---HAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEMH TRCIP || .| TREVP |
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Kinase | AqueK557.AA | Pkinase | 370-524 | 21 | 7.5e-15 | 53.6 | Pfam | 50-215 (293) | Show / Hide |
Range on Protein: 370-524 Range on HMM: 50-215/293 Sequence Identity: 21% (38 aa) EMNIASKICHPNLLQFIGAT-TEGNPIILTELMPT-----SLRKELE---TGGL--AYHAVLNISLDVACALNYLHLFKPHPILHRDISSADVLLQGTGF | | ...||| ...... ..... . .|... .| .. |.. .. . .. . ....|.|.| |.|||. .. .|. .| EIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNG- GWRA----KVSDYGSAN---LQPLIGRTTNPGNPVYSAPEAAN-PREHSPSMDVFSYGVLLLEMITRCIPLPEE |..| |.| . . || | | | ||| . ....|. |..|.|..| ||... | |.. --HIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH |
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Kinase | AqueK557.AA | Dicty5 | 363-517 | 27 | 1.5e-14 | 46.5 | In-house | 39-199 (260) | Show / Hide |
Range on Protein: 363-517 Range on HMM: 39-199/260 Sequence Identity: 27% (46 aa) NIMKFSHEMNIASKIC--HPNLLQFIGATTEGNPI--ILTELMPT-SLRKELETGGL------AYHAVLNISLDVACALNYLHLFKPHPILHRDISSADV .. | | | | . |||. . || . ..||. ||. | || | . .|.| .. .|| | |||. | . DWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMN---IIHRDLKSMNF LLQGTGFGWRAKVSDYG-SANLQPLIGRTTNPGNPVYSAPEAANPREHSPSMDVFSYGVLLLEMITR |. | .|. |.| | . . |.. | . . |.| | . ||.|.|. | ||.|| LITEN---WKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTR |
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Kinase | AqueK557.AA | TyrKc | 325-562 | 20 | 1.2e-13 | -1.89 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 325-562 Range on HMM: 1-280/280 Sequence Identity: 20% (60 aa) TMTGVVLGKGGWGEVKVADFRGLKVAAKCLYEIIISPHNIMKFSHEMNIASKI--CHPNLLQFIGATTE--------GNPIILTELMPT-SLRKELETGG | .|| | ||| . . ..|| |.| | .. | .|..| .|. |||.....|. |. . . |..|.|| .|.. | . ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR --LAYHAVLNISLDVACALNYLHLFKPHPILHRDISSADVLLQGTGFGWRAKVSDYGSANLQPLI------GRTTNP-----GN---PV-YSAPEAANPR | |......|| .||| ... |||. .|. . ..|.|| | . . . . |. |. |||. | . PKLCMKDLLSFCWQIACGMEYLHS---KNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG EHSPSMDVFSYGVLLLEMITRCIPLPEE-------------------RVGLIDG--------IRKASFRSLVQRCLIVEYRHCPTMNDIITEL . .. ||.|.||.. |. |.. . ... | . .. .. . ..| . ||...|. .. KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF |
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Kinase | AqueK557.AA | DRK | 326-468 | 32 | 6.4e-12 | 36.69 | In-house | 2-145 (258) | Show / Hide |
Range on Protein: 326-468 Range on HMM: 2-145/258 Sequence Identity: 32% (48 aa) MTGVVLGKGGWGEVKVADFRGLKVAAKCLYEIIISPHNIMK-FSHEMNIASKICHPNLLQFIGATTE-GNPIILTELMPT-SLRKEL--ETGGLAYHAVL |. |.|..||| || .|| | | | |... | | |. .. ||| ||.|. .. . | .| || || . | | . .. KIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMK NISLDVACALNYLHLFKPHPILHRDISSADVLLQGTGFGWRAKVSDYG . .|.| ..||| | |.||| | | |. ||.|.| QMMFDCAKGMIYLHCCNPI-IIHRDLKSHNLLVDEH---WQVKVADFG |
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Kinase | AqueK557.AA | Dicty4 | 327-402 | 36 | 4.2e-11 | 33.44 | In-house | 3-85 (277) | Show / Hide |
Range on Protein: 327-402 Range on HMM: 3-85/277 Sequence Identity: 36% (30 aa) TGVVLGKGGWGEVKVADFRGLKVAAKCL--YEIIISPHNIMKFSHEMNIASKICHPNLLQFIGATT-----EGNPIILTELMP ... .|||. ||| . || .|| | | . . . | .| .| .|| |||...| || | | . | ||.|| IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMP |
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Kinase | AqueK557.AA | Pkinase_Tyr | 325-446 | 24 | 1.2e-09 | 33.34 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 325-446 Range on HMM: 1-137/270 Sequence Identity: 24% (35 aa) TMTGVVLGKGGWGEVKVADFR------GLKVAAKCLYEIIISPHN--IMKFSHEMNIASKI-CHPNLLQFIGATT-EGNP---IILTELMPT-SLRKELE | .||.| |||. . . ...|| |.| .... . .| .|..| ... |||.....|. | .| | .| .|.|| .|.. | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR TG-----GLAYHAVLNISLDVACALNYLHLFKPHPILHRDI . | . |......|....||. . . |||. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDL |
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Kinase | AqueK557.AA | LISK | 501-522 | 54 | 1e-06 | 17.62 | In-house | 219-240 (296) | Show / Hide |
Range on Protein: 501-522 Range on HMM: 219-240/296 Sequence Identity: 54% (12 aa) SMDVFSYGVLLLEMITRCIPLP | ||||.|..|.|.||| . | SCDVFSFGIVLCEIITRVKADP |
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Kinase | AqueK557.AA | LISK | 330-388 | 26 | 3e-06 | 16.24 | In-house | 1-64 (296) | Show / Hide |
Range on Protein: 330-388 Range on HMM: 1-64/296 Sequence Identity: 26% (17 aa) VLGKGGWGEVKVADFR--GLKVAAKCLY---EIIISPHNIMKFSHEMNIASKICHPNLLQFIGA ..|||. |.| | | .| | . . . | .. .. |. . .. ||| .||.|. EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV |
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Kinase | AqueK557.AA | LISK | 420-468 | 40 | 0.001266 | 7.42 | In-house | 104-150 (296) | Show / Hide |
Range on Protein: 420-468 Range on HMM: 104-150/296 Sequence Identity: 40% (20 aa) LNISLDVACALNYLHLFKPHPILHRDISSADVLLQGT-GFGWRAKVSDYG ..|.||.||.. ||| . |.||| | .|. .||.|| | | VKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFG |
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Kinase | AqueK557.AA | DRK | 503-520 | 44 | 0.001445 | 7.99 | In-house | 184-201 (258) | Show / Hide |
Range on Protein: 503-520 Range on HMM: 184-201/258 Sequence Identity: 44% (8 aa) DVFSYGVLLLEMITRCIP ||.|... | |..|| .| DVYSFAIVLWECVTRQDP |
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Kinase | AqueK557.AA | Dicty4 | 503-520 | 50 | 0.007394 | 5.56 | In-house | 199-216 (277) | Show / Hide |
Range on Protein: 503-520 Range on HMM: 199-216/277 Sequence Identity: 50% (9 aa) DVFSYGVLLLEMITRCIP ||.|.| .| |. || .| DVYSFGIVLWEILTRQEP |
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Kinase | AqueK557.AA | Dicty4 | 535-564 | 28 | 0.011588 | 4.9 | In-house | 246-277 (277) | Show / Hide |
Range on Protein: 535-564 Range on HMM: 246-277/277 Sequence Identity: 28% (9 aa) ASFRSLVQRCLIVEYRHCPTMNDIITE--LND .|...|.|.|. . | |... || . |. PSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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Kinase | AqueK557.AA | Pkinase_Tyr | 503-523 | 43 | 0.082699 | 6.75 | Pfam | 196-218 (270) | Show / Hide |
Range on Protein: 503-523 Range on HMM: 196-218/270 Sequence Identity: 43% (10 aa) DVFSYGVLLLEMITRC-IP-LPE || |.|||. |..|.. .| |. DVWSFGVLMWEIFTYGEQPTYPG |