Gene AqueK550 (A.queenslandica)
AqueK550
Species: A.queenslandica
Alias: AqueK550
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
AqueK550.AA | Protein | None | 214 | None | Fasta, JSON |
AqueK550.kin_dom | Protein Kinase Domain | None | 166 | None | Fasta, JSON |
Protein domains of AqueK550.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | AqueK550.AA | TKL | 17-166 | 18 | 6.6e-29 | 101.23 | In-house | 132-364 (364) | Show / Hide |
Range on Protein: 17-166 Range on HMM: 132-364/364 Sequence Identity: 18% (44 aa) PELLRISLDVACALNYLHLFKP-----HPILHRDVSSANVLLQPMGG--------GLGGWRAKVSDYGTVS-LQPLA--------------------RTC . ..|..||.|...|||| .| ||.||| |.|.|. . |..|..|.|. ... .|. HQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTM NPG-NPVYSAPES-----PYP-----------RQHSPSMDVFSYGVLLIEMALCEFPEEEKSLR------------EAQIKAIKRPTLK----------- ... .| . ||| .|. .. |...||.|.|..| |.. .. |... . . .. .||... TQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCP ---------NLIERCLIENYKQRPTMSDIIKEL .|...| .. ..||....|.|.| CPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | AqueK550.AA | MLK | 19-116 | 30 | 8.7e-16 | 51.35 | In-house | 126-229 (291) | Show / Hide |
Range on Protein: 19-116 Range on HMM: 126-229/291 Sequence Identity: 30% (32 aa) LLRISLDVACALNYLHLFKPHPILHRDVSSANVLLQP-MGGGLGGWRAKVSDYGTVS-LQPL-A-RTCNPGNPVYSAPESP---YPRQHSPSMDVFSYGV .....|..| ...||| .|.|| ||| | |.|. . ... .|..| ||. .. . ...|.|.. . ||| . | . ||.|.|| AMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGV LLIEM .| || VLWEM |
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Kinase | AqueK550.AA | HH498 | 20-116 | 37 | 1.1e-13 | 39.32 | In-house | 124-219 (284) | Show / Hide |
Range on Protein: 20-116 Range on HMM: 124-219/284 Sequence Identity: 37% (38 aa) LRISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGGLGGWRAKVSDYG----TVSLQPLARTCNPGNPVYSAPESPY-PRQHSPSMDVFSYGVLLI ..||.||| |||| .||| ||| | |.|. | .|.| |.| .. | |||. . ||| . | |||||. . MTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDG------HAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIW EM || EM |
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Kinase | AqueK550.AA | TK | 11-166 | 14 | 1.8e-12 | 37.38 | In-house | 229-486 (486) | Show / Hide |
Range on Protein: 11-166 Range on HMM: 229-486/486 Sequence Identity: 14% (38 aa) TGGLAYPELLRISLDVACALNYLHLFKPHPI----LHRDVSSANVLLQPMGG-----GLGGWRAKVSDYG--------TVSLQPLARTCNPGNPVY---- .. | ..|| .....||.. ||| . |||. |.|. . . | .|..|.| . .. . KHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRP -------------------------SAPESPY---------PRQHSPSMDVFSYGVLLIEMA-LC-EFPEEEKS-------------------------- |||. . ... ||.|.|||. |. .. | . .. | MWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRS --------LREAQIKAIKR-------------PTLKNLIERCLIENYKQRPTMSDIIKEL .| .| . . . |. .| .. ..|||.|.. ..| GLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | AqueK550.AA | STE | 29-164 | 19 | 4.3e-12 | 39.11 | In-house | 163-353 (359) | Show / Hide |
Range on Protein: 29-164 Range on HMM: 163-353/359 Sequence Identity: 19% (41 aa) A-LNYLHLFKPHPILHRDVSSANVLLQPMGGGLGGWRAKVSDYGTVS-LQPLAR------------TCN------PGNPVYSAPESPYP------RQHSP . |.||| . | |||. .||.|| .| .| |. . |.. . |. | | . ||| . ... GLLYYLHSHH---IIHRDIKPANILL-----------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDT SMDVFSYGVLLIEMALCEFPEEE-KSLREAQIKAIKR-------------------------------------------PTLKNLIERCLIENYKQRPT . |. | | ..|||| . | . . .| .... | .|. |..||. ....||| KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT MSDIIK |. .| ASQLLK |
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Kinase | AqueK550.AA | CZAK | 20-122 | 31 | 1.3e-11 | 38.58 | In-house | 108-221 (279) | Show / Hide |
Range on Protein: 20-122 Range on HMM: 108-221/279 Sequence Identity: 31% (36 aa) LRISLDVACALNYLHL-FKPHPILHRDVSSANVLLQPMGG-------GLGGWRAKVSDYGTV---SLQPLARTCNPGNPVYSAPESPYPRQHSPSMDVFS . . .|.| |||| .|| |||||| || |.|| .|..|.| || | | . ||| .. ||.| WNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEKVDVYS YGVLLIEMALCEFP .| .| .. |. | FGMILWCIITCDQP |
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Kinase | AqueK550.AA | TKL-Unique | 20-117 | 27 | 2.2e-10 | 33.02 | In-house | 113-222 (290) | Show / Hide |
Range on Protein: 20-117 Range on HMM: 113-222/290 Sequence Identity: 27% (32 aa) LRISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGGLGG-----WRAKVSDYGTVSLQP--LARTCN----------PGNPVYSAPESPYP--RQH ... .|.| ...||| .| |.||| | |.|. . |..|..| |.. .. .. | | |.. ..||| | VKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVD------NNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQY SPSMDVFSYGVLLIEMA | . ||.|.|. |.|.| SEKSDVYSFGIVLWEIA |
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Kinase | AqueK550.AA | LRRK | 19-93 | 33 | 2.9e-10 | 32.49 | In-house | 166-249 (351) | Show / Hide |
Range on Protein: 19-93 Range on HMM: 166-249/351 Sequence Identity: 33% (29 aa) LLRISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGGL------GGWRAKVSDYGTVS----LQP-LARTCNPGNPVYSAPE .|.|.|..| ...||| ..| ||.||| | |.||. . . ||..|.|. . ... .|..| |||.. ||| KLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV-GNPGWMAPE |
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Kinase | AqueK550.AA | TK-Unique | 14-117 | 24 | 2e-09 | 28.77 | In-house | 128-233 (294) | Show / Hide |
Range on Protein: 14-117 Range on HMM: 128-233/294 Sequence Identity: 24% (28 aa) LAYPELLRISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGGLGGWRAKVSDYGTVS----LQPLARTC--NPGNPVYSAPESPY--PRQH-SPSM . . |... ..||...||. .. | |||... ||||. . ..|..|.| ......| .. . ||||.. ... .. ISPKDLYHFAWQIACGMEYLASQ-RKKIVHRDLCARNVLLTE------DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKS DVFSYGVLLIEMA || |.|||. |.. DVWSFGVLMWEIF |
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S_TKc | AqueK550.AA | S_TKc | 1-172 | 16 | 2.3e-07 | -68.84 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1-172 Range on HMM: 1-231/231 Sequence Identity: 16% (41 aa) M--------------------------------------------------------------------PT---SLRKELETGG-------LAYPELLRI .. .|.. .. | . . .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY SLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGGLGGWRAKVSDYGTVSLQPLARTCNPGNPVYSAPESPYPRQHSP-SMDVFSYGVLLIEMALCEF ..|||.|.| . |.|||. .|.|| . |..| | . | | | | ||| .... . |. | |..|.||. . MYQICCALEYCHSHG---IIHRDLKPENILLDE--------HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYP PEEEKSLREAQIKAIKRPTLKNLIERCLIENYKQRPTMSDIIK---ELNESIYV | . .. .| |. | .|..|..|| . ..||| .. . . . .. PFP---QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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TyrKc | AqueK550.AA | TyrKc | 3-166 | 15 | 2e-06 | -119.44 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 3-166 Range on HMM: 1-280/280 Sequence Identity: 15% (46 aa) TSLRKELETG-------------------------------------G------------------------------------------------LAYP .| |.| | | | . ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK ELLRISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGGLGGWRAKVSDYGTVSLQPLARTCNPG------NPVYS----------------APESP .|| .....|| .||| ... ||| |.|. . ..|.|| | |.| . .|. |||. DLLSFCWQIACGMEYLHS---KNCIHRDLAARNCLVGENH------TVKISDFG------LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI YPRQHSPSMDVFSYGVLLIEMA-LCEFPEEE-----KSLRE--AQIKAIKRPTLKNL----------------IERCLIENYKQRPTMSDIIKEL . .. ||.|.||.. |. ... | .. .| .| ...|. .|. ...| |. ..|||.|.|.... NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | AqueK550.AA | TAK1 | 26-93 | 35 | 4e-06 | 16.58 | In-house | 111-173 (284) | Show / Hide |
Range on Protein: 26-93 Range on HMM: 111-173/284 Sequence Identity: 35% (24 aa) VACALNYLHLFKPHPILHRDVSSANVLLQPMGGGLGGWRAKVSDYGTVSLQPLARTCNPGNPVYSAPE .| ...||| .| |. |||. .| || . | |. | ||. ||| | . . ||| CAQGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTL-----KICDFGTFCDMHQMMTCNRGTCRWMAPE |
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Kinase | AqueK550.AA | LRRK | 139-168 | 33 | 4e-06 | 17.56 | In-house | 322-351 (351) | Show / Hide |
Range on Protein: 139-168 Range on HMM: 322-351/351 Sequence Identity: 33% (10 aa) PTLKNLIERCLIENYKQRPTMSDIIKELNE . ...||. | .. |.||..|.|.| | . HMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
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Kinase | AqueK550.AA | TKL-Unique | 141-166 | 34 | 7e-06 | 16.89 | In-house | 265-290 (290) | Show / Hide |
Range on Protein: 141-166 Range on HMM: 265-290/290 Sequence Identity: 34% (9 aa) LKNLIERCLIENYKQRPTMSDIIKEL ...||..| . |||. ..||..| YRDLIQQCWHHDPSQRPSFDEIIHRL |
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Kinase | AqueK550.AA | TAK1 | 138-165 | 21 | 9e-06 | 15.35 | In-house | 257-284 (284) | Show / Hide |
Range on Protein: 138-165 Range on HMM: 257-284/284 Sequence Identity: 21% (6 aa) RPTLKNLIERCLIENYKQRPTMSDIIKE .. .... ..| .| .||.|... | PKRIEQFMKCCWDDNPEKRPSMQECVKY |
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Kinase | AqueK550.AA | Pkinase | 98-172 | 16 | 1e-05 | 21.33 | Pfam | 187-293 (293) | Show / Hide |
Range on Protein: 98-172 Range on HMM: 187-293/293 Sequence Identity: 16% (18 aa) RQHSPSMDVFSYGVLLIEMALCEFPEEEK------SLREAQIKAIKR-------------------------------PTLKNLIERCLIENYKQRPTMS . ..|. |..|.|..|.||.. ..| .. . .. |. |.. ...| .|..|| . |.||| QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQM-ICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-- DIIKELNESIYV .... .. .. --AEQILQHPWF |
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Kinase | AqueK550.AA | MLK | 139-166 | 25 | 1.2e-05 | 15.77 | In-house | 264-291 (291) | Show / Hide |
Range on Protein: 139-166 Range on HMM: 264-291/291 Sequence Identity: 25% (7 aa) PTLKNLIERCLIENYKQRPTMSDIIKEL . .|.|...| .. ..||... |...| EHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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Pkinase_Tyr | AqueK550.AA | Pkinase_Tyr | 5-53 | 28 | 7.5e-05 | 17.05 | Pfam | 98-144 (270) | Show / Hide |
Range on Protein: 5-53 Range on HMM: 98-144/270 Sequence Identity: 28% (14 aa) LRKE-LETGGLAYPELLRISLDVACALNYLHLFKPHPILHRDVSSANVLL ||| . . | ..|| .....|....||. . . |||. |.|. LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLV |
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Kinase | AqueK550.AA | TK-Unique | 138-166 | 24 | 0.000179 | 11.48 | In-house | 266-294 (294) | Show / Hide |
Range on Protein: 138-166 Range on HMM: 266-294/294 Sequence Identity: 24% (7 aa) RPTLKNLIERCLIENYKQRPTMSDIIKEL .... ||...|. .. ..||. ..|...| SHEMYNLMKSCWQWEPEERPSFRQIKHRL |
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Kinase | AqueK550.AA | Pkinase_Tyr | 139-166 | 28 | 0.001837 | 12.35 | Pfam | 243-270 (270) | Show / Hide |
Range on Protein: 139-166 Range on HMM: 243-270/270 Sequence Identity: 28% (8 aa) PTLKNLIERCLIENYKQRPTMSDIIKEL . . .|. .| .. ..|||.|.|. .| DEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | AqueK550.AA | Pkinase | 12-53 | 25 | 0.012015 | 10.44 | Pfam | 101-141 (293) | Show / Hide |
Range on Protein: 12-53 Range on HMM: 101-141/293 Sequence Identity: 25% (11 aa) GGL--AYPELLRISLDVACALNYLHLFKPHPILHRDVSSANVLL |.. . |. .. . ....|.|.| |.|||. ..|.|. GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILI |
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Kinase | AqueK550.AA | HH498 | 143-166 | 33 | 0.165645 | 0.09 | In-house | 261-284 (284) | Show / Hide |
Range on Protein: 143-166 Range on HMM: 261-284/284 Sequence Identity: 33% (8 aa) NLIERCLIENYKQRPTMSDIIKEL ||| .| . ||. ..|. | NLIQMCWHPCPENRPDFDQIVTIL |
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Kinase | AqueK550.AA | CZAK | 141-166 | 38 | 0.228009 | 0.92 | In-house | 254-279 (279) | Show / Hide |
Range on Protein: 141-166 Range on HMM: 254-279/279 Sequence Identity: 38% (10 aa) LKNLIERCLIENYKQRPTMSDIIKEL | |||.| | ||. . |. | LGELIEMCWNKNPDERPSFKQILQHL |
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Kinase | AqueK550.AA | Pkinase_Tyr | 105-116 | 58 | 1.204569 | 2.81 | Pfam | 196-207 (270) | Show / Hide |
Range on Protein: 105-116 Range on HMM: 196-207/270 Sequence Identity: 58% (7 aa) DVFSYGVLLIEM || |.|||. |. DVWSFGVLMWEI |