Gene AqueK533 (A.queenslandica)

AqueK533

Species: A.queenslandica
Alias: AqueK533
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-a2

Sequence

Name Sequence Type Origin Length Description Download
AqueK533.AA Protein None 449 None Fasta, JSON
AqueK533.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of AqueK533.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK533.AA TKL 178-423 21 1e-53 184.78 In-house 1-364 (364) Show / Hide 
Range on Protein: 178-423
Range on HMM: 1-364/364
Sequence Identity: 21% (80 aa)

LGKGGWGVVWIGEFRG----------QKVAVKQMHN--IIKSDE-----------------------FIKLLHREINTMSQLRHPNLLQFIGAVLDDPSD
.|.|| |.|. |..||          . ||||...     ....                       | . . .||. ||.|||||..||.|.... |..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------NPMIITEVM-DTSLRNAYKSKELTPDPGCRPVILSIMRDVAVGLNYLHC--L----PDPIIHRDVSSANVLLESKGD----------KK
           ...|..| .   ||.. .            ........|.| |.||||        . ||||||  |.|.|. ...           . 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

WKTKISDFGSASLAHA----------------------AVTEAPGALVYSAPESIATL--YRKK---------RKQTPKMDSYSYGVLLCEILTCSFPEV
|. ||.||| .   .                       .     | . . ||| .     |..|         .. ..|.| ||.|..|.||||.  |. 
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

-EKFE------------TLSL--QVRASSP-----------------RLHQLIVLCINEEPDKRPTMSEIIVKL
 ....             .    . |   |                 .. .|.  | ...|.|||...||. .|
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK533.AA TK 172-423 15 4.6e-38 124.65 In-house 1-486 (486) Show / Hide 
Range on Protein: 172-423
Range on HMM: 1-486/486
Sequence Identity: 15% (75 aa)

SLSKNQLGKGG---WGVVWIGEFRG---------------------------QKVAVKQMH--NIIKSDEFIK-LLH---------REINTMSQLR----
    ..||.|    .|.|. || ||                           ..||||...  .   ..||.   .|         .| . |....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLLQFIGAVLDDPS----------DNPMIITEVMD-TS----LRNAYKSKE----------------------------------------------
 |||.....|..... .            .||..| |.  .    ||.  ...                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------LTPDPGCRPVILS-------------------IMRDVAVGLNYLHCLPD----PIIHRDVSSANVLLESKGDKKWK-------TKISDFGSAS-
      . |.| .    |.                   .....| |. ||| ..      ..|||.   |.|. ... .||.        ||.||| .  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LAHAA-------VTEAPGALV-------------------------YSAPESIA--TLYRK--KRKQTPKMDSYSYGVLLCEILT---CSFP----
    || .        ... .|. .                         . |||...  .  ..  ..| |.| | .|.|||. ||.|     ..    
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

-----------EVEKFET----------------LSLQ--VRASS-------------PRLHQLIVLCINEEPDKRPTMSEIIVKL
           || .. .                . .   . ...             . ...|.  | ...|..|||.|..  .|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK533.AA S_TKc 172-427 23 2.8e-32 114.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 172-427
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

SLSKNQLGKGGWGVVWIGEFRG--QKVAVKQMHNIIKSDEFIKLLHREINTMSQLRHPNLLQFIGAVLDDPSDNPMIITEVMDT---SLRNAYKSKEL--
    ...|||. |.|. .  ..  ..||.|...         . . |||. ... .|||. .....  |   |.  ...| .|.   .|.   |..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

TPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFGSASLAHAAVTEAPGALVYSAPESIATLYRKKRKQTP-KMDS
.. |    .. ..|. .. .|.|.| .   |||||.  .|.|| .        ||.|||.| .     |   | . | ||| .        . .. | | 
LRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL--------GYGKCKCDW

YSYGVLLCEILTCSFPEVEKFETLSLQVRASSPRLHQLIVLCINEEPDKRPTMSEIIV-----KLDRFI
.| |..| | |.   |     ...  ...  || . ..|  | . .|.||||  |.       |.. ..
WSCGCILYEMLCGYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK533.AA Dicty4 175-323 33 4.5e-32 104.39 In-house 4-159 (277) Show / Hide 
Range on Protein: 175-323
Range on HMM: 4-159/277
Sequence Identity: 33% (55 aa)

KNQLGKGGWGVVWIGEFRGQKVAVKQM--HNIIKSDEFIKLLHREINTMSQLRHPNLLQFIGAVL---DDPSDNPMIITEVM-DTSLRNAYKS------K
 . .|||. | |  |  ||..|||| .  ||.  . .... ...|.. |...||||...| || .     |.. ..| || |  ..| .   .      .
EQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGK-MCIVTEYMPKGNLYSLLHDKPSEQQQ

ELTPDPGCRPVILS---IMRDVAVGLNYLHC-LPDPIIHRDVSSANVLLESKGDKKWKTKISDFG
. ..|    | |..   ...|.| |.|.|||  |. |||||  |.| |     || |. |..|||
SIKLD---WPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLV----DKNWRVKVCDFG
Kinase AqueK533.AA MLK 172-379 25 1e-30 103.86 In-house 1-235 (291) Show / Hide 
Range on Protein: 172-379
Range on HMM: 1-235/291
Sequence Identity: 25% (63 aa)

SLSKNQLGKGGWGVVWIGEFRGQK-----VAVKQMH----NIIKSDEFIKLLHREINTMSQLRHPN----LLQFIGAVLDDPSDNPMIITEVMDT-SLRN
 . .  .|.|. |.|| |..|..      ||||. .     . .... .. . .|..  . |.|||      || |. |..|  .  |..| ..  || |
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSLYN

AYKSKELTPDPGC----------RPVILSIMRDVAVGLNYLHC-LPDPIIHRDVSSANVLLES-----KGDKKWKTKISDFGSASLAHAA---VTEAPGA
  ....  ...              ...... ..| |..|||. .|.||||||  | |.|.       ...   . ||.||| .   |      . ..| 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHG---TLKICDFGTSRDWHQMCTNMMSNAGT

LVYSAPESI----ATLYRKKRKQTPKMDSYSYGVLLCEILTCSFP
. . ||| |    .. | .      | | .|.||.| |.||.  |
YAWMAPEVIQQFRCEKYSE------KCDVWSWGVVLWEMLTREVP
Kinase AqueK533.AA DRK 175-375 35 1.3e-29 97.47 In-house 4-197 (258) Show / Hide 
Range on Protein: 175-375
Range on HMM: 4-197/258
Sequence Identity: 35% (73 aa)

KNQLGKGGWGVVWIGEFRGQKVAVKQMHNIIKS-DEFIKLLHREINTMSQLRHPNLLQFIGAVLDDPSDNPMIITEVMDT-SLRNAYKSKELTPDPGCRP
 |  |.|..| |. |  || .|||| . |      .|.. .||||| |.||||||  ||.|. .  |.  . |..| |   || |      .  |    |
GNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPD--ICICMEYMPRGSLYNILHDESIEMD---WP

VILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFGSAS-----LAHAAVTEAPGALVYSAPESIATLYRKKRKQTPKMDSYSYG
 ....| |.| |..||||    |||||  | | |     |  |. |..||| .      . | .   . |     |||  .         | | | ||..
LMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLV----DEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLR-----NQRYTEKADVYSFA

VLLCEILT
. | |..|
IVLWECVT
Kinase AqueK533.AA TKL-Unique 176-375 28 3.9e-28 96.4 In-house 3-223 (290) Show / Hide 
Range on Protein: 176-375
Range on HMM: 3-223/290
Sequence Identity: 28% (64 aa)

NQLGKGGWGVVWIGEFRGQKVAVKQMH-NIIKSDEFIKLLHREINTMSQLR-HPNLLQFIGAVLDDPSDNP--MIITEVMDT-SLRNAYK---------S
| .| || |.|  |..|| .||.|| | |  .| |... ...|.|.|. |. |||.....|.  |.  ..|   |..| ..  ||..            .
NKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

KELTPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESK-GDKKWKTKISDFGSASLAHAAVTEAPGAL------------VYSAPESIA
.......    ..... .|.| |..||| .  ||||||  | |.|. ..    .|. ||.||| . ..    ..  . .             ..||| . 
NNCKLNMQ---QRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

TLYRKKRKQTPKMDSYSYGVLLCEILT
 .     . . | | ||.|. | ||.|
MNF---CQYSEKSDVYSFGIVLWEIAT
Kinase AqueK533.AA CZAK 171-379 31 5.6e-28 98.75 In-house 1-221 (279) Show / Hide 
Range on Protein: 171-379
Range on HMM: 1-221/279
Sequence Identity: 31% (74 aa)

LSLSKNQLGKGGWGVVWIGEFRGQKVAVKQMHNII--KSDEF--IKLLHREINTMSQLRHPNLLQFIGA-VLDDPSDNPMIITEVMD-TSLRN--AYKSK
|   .   |.|  | |  .  ||  ||.| .| .     ||        .|.  || |.||| .||.||  .| | .   |..| |   |||     .. 
LKFGQ-TIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGP-NHHCIVMEWMGGGSLRRLLTDHYF

ELTPDPGCRPVILSIMRDVAVGLNYLHC--LPDPIIHRDVSSANVLLESKGD---------KKWKTKISDFGSA---SLAHAAVTEAPGALVYSAPES-I
 . . |  .   ... .|.| | ||||    | ||.||| || |.||..  .         .  . ||.|||            | . | | . |||  .
YHKQNPHLQ---WNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFK

ATLYRKKRKQTPKMDSYSYGVLLCEILTCSFP
. .|      |.| | ||.| .| .|.||  |
GENY------TEKVDVYSFGMILWCIITCDQP
Kinase AqueK533.AA STE 173-326 24 3.1e-25 86.12 In-house 1-195 (359) Show / Hide 
Range on Protein: 173-326
Range on HMM: 1-195/359
Sequence Identity: 24% (50 aa)

LSK-NQLGKGGWGVVWIG-----------------EFRGQKVAVKQMH---------------NIIKSDEFIKLLHREINTMSQLR--HPNLLQFIGAVL
. .  ..|||. |.|  .                 .  |. .|.|||.               . .| .| .. . .||..|....  |||  ...|. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DDP-----SDNPMIITEVMD-TSLRNAYKSKELTPDPGC----------RPVILSIMRDVAVG-LNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKIS
..       |.  |. | ||  ||.  .|.|  ...|             ..|  | |..  | |.||| .   |||||. .||.||          |..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL---------VKLC

DFGSAS
||| ..
DFGVCG
Kinase AqueK533.AA Pkinase_Tyr 171-323 25 8e-23 77.92 Pfam 1-156 (270) Show / Hide 
Range on Protein: 171-323
Range on HMM: 1-156/270
Sequence Identity: 25% (41 aa)

LSLSKNQLGKGGWGVVWIGEFR------GQKVAVKQMHNIIKSDE-FIKLLHREINTMSQL-RHPNLLQFIGAVL--DDPSDNPMIITEVMDT-SLRNAY
...   .||.|  |.|. |. .      ...|||| . .   ... ... . ||...|.|| .|||.....|...  ..|. ...|..| |   .|..  
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYL

KSKELTPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFG
...   ..| . . .|.. ...| |..||.  .  .||||.   |.|...   .. . ||.|||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTE---NN-VVKICDFG
Kinase AqueK533.AA TK-Unique 172-375 24 8.1e-22 72.1 In-house 1-234 (294) Show / Hide 
Range on Protein: 172-375
Range on HMM: 1-234/294
Sequence Identity: 24% (61 aa)

SLSKNQLGKGGWGVVWIGEFRG-------QKVAVKQMHNIIKSDEFIKLLHREINTMSQLR-HPNLLQFIGAVLDDPSDNPMIITEVMDTS-----LR--
.  ....|.|  | || ||..|       ||...  |...  .|.  . . .||. |..|  |||..|..|.  ..  ...||| | .  .     ||  
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTC

--------------------NAYKSKE-LTPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFGSAS------LAH
                    ......| ..|        .... ..| |..||. ... |.|||... |||| .    . . ||.||| |          
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISP-----KDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE----DKVCKICDFGMARDVYTNGVYS

AAVTEAPGALVYSAPESIA-TLYRKKRKQ-TPKMDSYSYGVLLCEILT
   .. .  . . ||||.  .    ..   |.| | .|.|||. ||.|
MMCSQGRIPIRWMAPESLKCY----HGMYHTTKSDVWSFGVLMWEIFT
Kinase AqueK533.AA Pkinase 172-423 20 1.3e-21 77.52 Pfam 1-293 (293) Show / Hide 
Range on Protein: 172-423
Range on HMM: 1-293/293
Sequence Identity: 20% (64 aa)

SLSKNQLGKGGWGVVWIGEFRGQK--VAVKQMHNIIKSDEFIKLLHR--EINTMSQLRHPNLLQFIGAVLDDPSDNPMIITEVMDT-----SLRNAYK--
   . ..|.|. |.|...  .|    ||||..    ..... . . |  ||  |  |.||| ....... |  .|.. ...| ..      .|    .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

-SKEL--TPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFGSA----SLAHAAVTEAPGALVYSAPESIATLYRK
 .. .  ...     .. ..|. .. ||.|.|     |||||. ..|.|. ..|. . . ||.|||.|           |   | . | ||| |     .
RHGCFYFSEW-----ECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----G

KRKQTPKMDSYSYGVLLCEILTCSFPEVEK------------FETLSLQVRASS------------------------PRLHQLIVLCINEEPDKRPTMS
 .. .|| | .|.|..| | |.  .|  ..            ..... ... ..                        . . ..|  |..  | ||||  
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

EIIVK--L
.|     .
QILQHPWF
Kinase AqueK533.AA TyrKc 171-423 23 8.2e-21 76.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 171-423
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

LSLSKNQLGKGGWGVVWIGEFRGQKVAVKQMHNIIKSDEFIKLLHREINTMSQL--RHPNLLQFIGAVLDD-----PSDNPMIITEVMDT-SLRNAYKSK
..| | .|| |  |.|. |. . ..|||| ...       .. ..||.. |..|  .|||.....|.....      .. .||..| |.  .|..  ...
ITLGK-KLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

ELTPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFGSASLAHAA--------VT------EAP--GALVYSAPES
. .    | .  ||.. ..| | .|||    ..||||    |.|. ...      |||||| .   .          .        .     .   |||.
RPK---LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

IATLYRKKRKQTPKMDSYSYGVLLCEILT---CSFPE--------------VEKFETLSLQVRA-------SSPRLHQLIVLCINEEPDKRPTMSEIIVK
|     ...| |.| | .|.||.. ||.|      |.              |.. . .     .        .. ..|..  | .|.|..|||.|||. .
I-----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase AqueK533.AA LISK 177-235 40 6.8e-17 51.24 In-house 1-64 (296) Show / Hide 
Range on Protein: 177-235
Range on HMM: 1-64/296
Sequence Identity: 40% (26 aa)

QLGKGGWGVVWIGEFR--GQKVAVKQMH---NIIKSDEFIKLLHREINTMSQLRHPNLLQFIGA
 .|||. | |  |. |  || .|.|. |   |  . .|..| . ||. .|  ||||| .||.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV
Kinase AqueK533.AA Dicty4 395-425 33 1.7e-09 27.98 In-house 245-277 (277) Show / Hide 
Range on Protein: 395-425
Range on HMM: 245-277/277
Sequence Identity: 33% (11 aa)

SPRLHQLIVLCINEEPDKRPTMSEIIVK--LDR
.|.. .||. | ...| .||...||| .  |. 
PPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK533.AA Pkinase_Tyr 395-423 34 5e-07 24.43 Pfam 242-270 (270) Show / Hide 
Range on Protein: 395-423
Range on HMM: 242-270/270
Sequence Identity: 34% (10 aa)

SPRLHQLIVLCINEEPDKRPTMSEIIVKL
.. ...|. .| ...|..|||.|||. .|
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK533.AA MLK 395-423 31 5.2e-07 20.5 In-house 263-291 (291) Show / Hide 
Range on Protein: 395-423
Range on HMM: 263-291/291
Sequence Identity: 31% (9 aa)

SPRLHQLIVLCINEEPDKRPTMSEIIVKL
.... .|.  | |..| |||....|. .|
PEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK533.AA LISK 279-323 42 7e-07 18.17 In-house 108-150 (296) Show / Hide 
Range on Protein: 279-323
Range on HMM: 108-150/296
Sequence Identity: 42% (19 aa)

RDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFG
.|.| |. |||     |||||  | |.|.  ...  |. |. |||
LDIACGMSYLHS--MNIIHRDLKSKNCLVRENDNNQWRIKVCDFG
Kinase AqueK533.AA DRK 395-425 38 1e-06 18.75 In-house 228-258 (258) Show / Hide 
Range on Protein: 395-425
Range on HMM: 228-258/258
Sequence Identity: 38% (12 aa)

SPRLHQLIVLCINEEPDKRPTMSEIIVKLDR
.|   ||.  | ||.|  ||.| |..  |. 
PPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK533.AA TK-Unique 394-423 30 2e-06 18.39 In-house 265-294 (294) Show / Hide 
Range on Protein: 394-423
Range on HMM: 265-294/294
Sequence Identity: 30% (9 aa)

SSPRLHQLIVLCINEEPDKRPTMSEIIVKL
.|.....|.  |...||..||. ..|. .|
CSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK533.AA TKL-Unique 396-423 35 1.6e-05 15.69 In-house 263-290 (290) Show / Hide 
Range on Protein: 396-423
Range on HMM: 263-290/290
Sequence Identity: 35% (10 aa)

PRLHQLIVLCINEEPDKRPTMSEIIVKL
...  ||  | . .|..||. .||| .|
KEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK533.AA CZAK 398-423 42 0.000179 12.34 In-house 254-279 (279) Show / Hide 
Range on Protein: 398-423
Range on HMM: 254-279/279
Sequence Identity: 42% (11 aa)

LHQLIVLCINEEPDKRPTMSEIIVKL
|  ||  | |  || ||. ..|.. |
LGELIEMCWNKNPDERPSFKQILQHL
Kinase AqueK533.AA LISK 396-423 32 0.000351 9.26 In-house 269-296 (296) Show / Hide 
Range on Protein: 396-423
Range on HMM: 269-296/296
Sequence Identity: 32% (9 aa)

PRLHQLIVLCINEEPDKRPTMSEIIVKL
| ...| . |.. .|..||. .||. .|
PPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase AqueK533.AA STE 395-418 41 0.027157 4.05 In-house 327-350 (359) Show / Hide 
Range on Protein: 395-418
Range on HMM: 327-350/359
Sequence Identity: 41% (10 aa)

SPRLHQLIVLCINEEPDKRPTMSE
|| ... | .| . .|.|||| |.
SPEFKDFINKCLQKDPNKRPTASQ
Kinase AqueK533.AA LISK 364-375 58 0.061136 1.86 In-house 223-234 (296) Show / Hide 
Range on Protein: 364-375
Range on HMM: 223-234/296
Sequence Identity: 58% (7 aa)

YSYGVLLCEILT
.|.|..|||| |
FSFGIVLCEIIT