Gene AqueK489 (A.queenslandica)
AqueK489
Species: A.queenslandica
Alias: AqueK489
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK489.AA | Protein | None | 1814 | None | Fasta, JSON |
| AqueK489.kin_dom | Protein Kinase Domain | None | 173 | None | Fasta, JSON |
Protein domains of AqueK489.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| LRR_TYP | AqueK489.AA | LRR_TYP | 210-233 | 25 | 0.003826 | 17.69 | SMART | 1-24 (24) | Show / Hide |
Range on Protein: 210-233 Range on HMM: 1-24/24 Sequence Identity: 25% (6 aa) FNNLQKVQMHHNRITDIPHELFSL ||.. ..|..| .|...|. LPNLRELDLSNNQLTHLPPGAFQG |
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| LRR_1 | AqueK489.AA | LRR_1 | 212-233 | 29 | 0.00731 | 14.32 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 212-233 Range on HMM: 1-26/26 Sequence Identity: 29% (8 aa) NLQKVQMHH-N--RIT-DIPHE-LFSL |||. . . | ..| .||.. . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_BAC | AqueK489.AA | LRR_BAC | 233-252 | 30 | 0.623623 | 2.79 | SMART | 1-20 (20) | Show / Hide |
Range on Protein: 233-252 Range on HMM: 1-20/20 Sequence Identity: 30% (6 aa) LPRIKDIDLSFNLISALPSS |..| .. |.| .. || PPHLKWLNVSNNQLTELPEL |
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| LRR_1 | AqueK489.AA | LRR_1 | 235-256 | 22 | 1.071191 | 6.64 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 235-256 Range on HMM: 1-26/26 Sequence Identity: 22% (6 aa) RIKDIDLSF-N--LIS-ALPSS-IHSN ... .||| | .. .|.| . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | AqueK489.AA | LRR_1 | 189-211 | 22 | 51.265856 | 0.68 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 189-211 Range on HMM: 1-26/26 Sequence Identity: 22% (6 aa) SFTYVGLSS-N--LL-KCIPEQILRFN . .. ||. | | ..||. .. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | AqueK489.AA | LRR_1 | 260-281 | 40 | 0.000214 | 19.76 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 260-281 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) SLQSLNLSN-N--NLT-QLPSY-FKHS .||.|.||. | ||| ..|. | . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_TYP | AqueK489.AA | LRR_TYP | 260-280 | 50 | 0.019307 | 13.9 | SMART | 3-24 (24) | Show / Hide |
Range on Protein: 260-280 Range on HMM: 3-24/24 Sequence Identity: 50% (11 aa) SLQSLNLSNNNLTQLPSY-FKH .|..|.||||.||.||. | . NLRELDLSNNQLTHLPPGAFQG |
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| LRR_BAC | AqueK489.AA | LRR_BAC | 258-277 | 50 | 0.025568 | 13.38 | SMART | 1-20 (20) | Show / Hide |
Range on Protein: 258-277 Range on HMM: 1-20/20 Sequence Identity: 50% (10 aa) ANSLQSLNLSNNNLTQLPSY ..|..|| |||.|| || PPHLKWLNVSNNQLTELPEL |
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| LRR_1 | AqueK489.AA | LRR_1 | 282-303 | 22 | 0.036352 | 11.85 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 282-303 Range on HMM: 1-26/26 Sequence Identity: 22% (6 aa) HLRSLDISS-N--LFS-SVPDC-LTVM .|..||.|. | .. ..|. . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_BAC | AqueK489.AA | LRR_BAC | 280-299 | 30 | 0.138458 | 7.78 | SMART | 1-20 (20) | Show / Hide |
Range on Protein: 280-299 Range on HMM: 1-20/20 Sequence Identity: 30% (6 aa) HSHLRSLDISSNLFSSVPDC .||..|..|.| .. |. PPHLKWLNVSNNQLTELPEL |
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| LRR_TYP | AqueK489.AA | LRR_TYP | 281-303 | 30 | 0.30321 | 4.1 | SMART | 2-24 (24) | Show / Hide |
Range on Protein: 281-303 Range on HMM: 2-24/24 Sequence Identity: 30% (7 aa) SHLRSLDISSNLFSSVPDCLTVM ..||.|| |.| ....|. . PNLRELDLSNNQLTHLPPGAFQG |
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| LRR_1 | AqueK489.AA | LRR_1 | 305-327 | 29 | 0.011975 | 13.56 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 305-327 Range on HMM: 1-26/26 Sequence Identity: 29% (8 aa) HLTTLNISS-N-IGIE-IIPYE-LGNL .|..|..|. | .. || . . || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| COR | AqueK489.AA | COR | 691-717 | 24 | 0.000813 | 7.89 | In-house | 229-261 (434) | Show / Hide |
Range on Protein: 691-717 Range on HMM: 229-261/434 Sequence Identity: 24% (8 aa) SQYQIQRLYKF------ESLPMSLWPRLLSHLL ......| |.. ||...|||.. .|. DCRYLRRHYHYCMDHHHMFLPAGFWPRFQVRLH |
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| Kinase | AqueK489.AA | TKL | 965-1137 | 19 | 2.3e-23 | 80.98 | In-house | 124-364 (364) | Show / Hide |
Range on Protein: 965-1137
Range on HMM: 124-364/364
Sequence Identity: 19% (49 aa)
SMEDVILEHTISVSPFLRMRIVYQLASALKTLHSLK--------IIHRNVCLENIIVYSL---------SLDEQVNIKLG--GFSRSCLEMSQGLAVG--
| ..... . .|.|.... |... ||| . ||||. .|| | . . .....|.. |.||. .... . .
SLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTT
------------EHGRFP------APEMSNYL---------------YEYDQRADVFSFAFTSYEILTRKKLKCRKGVRFQTA---------------TG
... |||. . .||....||.||. .|||||.. .. .
MMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-------PYYDYPYMPMIFQDPFEEMFMM
NAD---RPNLK----------PLNGLCPYFTPLLDKCWNNDPHKRPYFIEILHQF
..| || .. | . | . |. .||. ||.||| | |||...
VCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | AqueK489.AA | LRRK | 981-1080 | 29 | 9.8e-14 | 44.95 | In-house | 165-279 (351) | Show / Hide |
Range on Protein: 981-1080 Range on HMM: 165-279/351 Sequence Identity: 29% (34 aa) LRMRIVYQLASALKTLHSLK--IIHRNVCLENIIVYSLSLD-------EQVNIKLG--GFSR--SCLEMSQGLAVGEHGRFPAPEMSNYL--YEYDQRAD |. .|..| |.... ||| . ||||. .||.. |.. . ..|..|.. | || .|. |. ... .. ||| .| ||.. .| LKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVD VFSFAFTSYEILTRK ..||. .|.|||. CYSFGMILWELLTRQ |
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| Kinase | AqueK489.AA | RIPK | 1065-1137 | 28 | 2.9e-12 | 38.06 | In-house | 210-290 (290) | Show / Hide |
Range on Protein: 1065-1137 Range on HMM: 210-290/290 Sequence Identity: 28% (23 aa) DVFSFAFTSYEILTRKKLKCRKGVRFQTATGNA--DRPNLKPLNGLCPY------FTPLLDKCWNNDPHKRPYFIEILHQF || |||.. .|.||.|. .. . . . ||.|.|.. .| |. .|| || .|| |.|. .. DVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT |
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| S_TKc | AqueK489.AA | S_TKc | 893-1138 | 18 | 1.2e-10 | -20.92 | SMART | 14-231 (231) | Show / Hide |
Range on Protein: 893-1138 Range on HMM: 14-231/231 Sequence Identity: 18% (49 aa) TVFKGEYGS--VPIAVKPYPPPNDRSANNPFLSFWHEITTLQYATQTDQCPYIIDPLLATTDPFSLVFSFAMF--CSMEDVILEHTIS-----VSPFLRM .|.|. . |.| . ... || |. . . ..| | . .|. .. .. |.| .. .. KVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR RIVYQLASALKTLHSLKIIHRNVCLENIIVYSLSLDEQVNIKLGGFSRSCLEMSQGLAVGEHGRFPAPEMSNYLYEYDQ-RADVFSFAFTSYEILTRKKL ...||...||. .||..|||| . ||| . . .||.. | ... . . . . |||. |. ..|. |. . || |... . FYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL--TTFCGTPW--YMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPP KCRKGVRFQTATGNADRPNLKPLNGLCPYFTPLLDKCWNNDPHKRPYFIEIL--------HQFT . . | | . ...||.. || ||| |.| |.. FP-QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | AqueK489.AA | MLK | 1109-1137 | 56 | 1.2e-10 | 31.15 | In-house | 251-280 (280) | Show / Hide |
Range on Protein: 1109-1137 Range on HMM: 251-280/280 Sequence Identity: 56% (17 aa) CP-YFTPLLDKCWNNDPHKRPYFIEILHQF || . |. ||| |||||| | |||.|. CPEPWAKLMQDCWNQDPHKRPKFSEILQQL |
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| TyrKc | AqueK489.AA | TyrKc | 893-1137 | 19 | 9.8e-09 | -81.45 | SMART | 14-280 (280) | Show / Hide |
Range on Protein: 893-1137 Range on HMM: 14-280/280 Sequence Identity: 19% (56 aa) TVFKGEYGSVPIAVKPYPPPNDRSANNPFLSFWHEITTLQYA-TQTDQCPYIIDPLLATT---------DPFSLVFSFAMFCSMEDVILEHTISVSPFLR .|.||.. .. ||| . | .|. . . | |. . . | .| .|. .. . | . .| ... EVYKGTWK-IQVAVKMLKEDA-------REDFMREARIMCKLGG---HHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDL MRIVYQLASALKTLHSLKIIHRNVCLENIIVYSLSLDEQVNIKLGGFSRSCLEMSQ--------GLAVGE--HGR--FP----APEMSNYLYEYDQRADV . .| |. ||| ..||| |. | .|. .| . | | . . | .|. .| ||| || ... || LSFCWQIACGMEYLHSKNCIHRDLAARNCLV-----GENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY-GKFTTKSDV FSFAFTSYEILTR-KKLKC------RKGVRFQTATGNADRPNLKPLN-------GLCPYFTPLLDKCWNNDPHKRPYFIEILHQF .|| . .||.|. .. . . . .|. | . .. . .||. ||..|| | || ..| WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | AqueK489.AA | TKL-Unique | 1115-1137 | 47 | 1.4e-08 | 26.53 | In-house | 268-290 (290) | Show / Hide |
Range on Protein: 1115-1137 Range on HMM: 268-290/290 Sequence Identity: 47% (11 aa) LLDKCWNNDPHKRPYFIEILHQF |...||. || .||.|.||.| LIQQCWHHDPSQRPSFDEIIHRL |
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| Kinase | AqueK489.AA | MLK | 1115-1137 | 52 | 4.4e-08 | 24.26 | In-house | 269-291 (291) | Show / Hide |
Range on Protein: 1115-1137 Range on HMM: 269-291/291 Sequence Identity: 52% (12 aa) LLDKCWNNDPHKRPYFIEILHQF |. .||| |||||| | .|. .. LMKQCWNQDPHKRPSFRQIVQHL |
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| Kinase | AqueK489.AA | TKL-Unique | 978-1080 | 27 | 1.5e-07 | 22.87 | In-house | 108-225 (290) | Show / Hide |
Range on Protein: 978-1080 Range on HMM: 108-225/290 Sequence Identity: 27% (32 aa) SPFLRMRIVYQLASALKTLHSLK--IIHRNVCLENIIVYSLSLDEQVNIKLGGFSRSCLEMSQ-GLAVGEHG-----------RFPAPEMSNYL-YEYDQ .. .|.... . |... .||... ||||. |. | . | ..|||. .|. | . . ..|| | |||. . . . |.. NMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSE RADVFSFAFTSYEILTRK .||.||.. .||.||| KSDVYSFGIVLWEIATRK |
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| Kinase | AqueK489.AA | Dicty5 | 1115-1141 | 44 | 2.5e-07 | 21.26 | In-house | 234-260 (260) | Show / Hide |
Range on Protein: 1115-1141 Range on HMM: 234-260/260 Sequence Identity: 44% (12 aa) LLDKCWNNDPHKRPYFIEILHQFTKPM | ||| ||.|| |.||. | . . LIKKCWQQKPHNRPSFKEICKYFESII |
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| Kinase | AqueK489.AA | HH498 | 1047-1080 | 38 | 2e-06 | 16.03 | In-house | 190-223 (284) | Show / Hide |
Range on Protein: 1047-1080 Range on HMM: 190-223/284 Sequence Identity: 38% (13 aa) RFPAPEMSNYLYEYDQRADVFSFAFTSYEILTRK |. ||| |. .||||.| .|..||. RWMAPEVFSQCQKYSIKVDVFSYAMCIWEMHTRE |
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| Kinase | AqueK489.AA | LRRK | 1110-1139 | 33 | 2e-06 | 19.02 | In-house | 322-351 (351) | Show / Hide |
Range on Protein: 1110-1139 Range on HMM: 322-351/351 Sequence Identity: 33% (10 aa) PYFTPLLDKCWNNDPHKRPYFIEILHQFTK ... |...||..|| ||| |..|. . HMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
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| Kinase | AqueK489.AA | Dicty4 | 1110-1139 | 34 | 2e-06 | 17.5 | In-house | 246-277 (277) | Show / Hide |
Range on Protein: 1110-1139 Range on HMM: 246-277/277 Sequence Identity: 34% (11 aa) PYFTPLLDKCWNNDPHKRPYFIEILHQ--FTK | .. |. .||..|| .|| | ||. . PSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | AqueK489.AA | Jak | 988-1024 | 29 | 5e-06 | 17.39 | In-house | 126-162 (299) | Show / Hide |
Range on Protein: 988-1024 Range on HMM: 126-162/299 Sequence Identity: 29% (11 aa) QLASALKTLHSLKIIHRNVCLENIIVYSLSLDEQVNI |.......|.. ..||..|| ||.| . ... |.| QICWGMHYLEDKRYIHGDVCARNILVDREGHWCCVKI |
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| Kinase | AqueK489.AA | HH498 | 1115-1137 | 34 | 2.3e-05 | 12.53 | In-house | 262-284 (284) | Show / Hide |
Range on Protein: 1115-1137 Range on HMM: 262-284/284 Sequence Identity: 34% (8 aa) LLDKCWNNDPHKRPYFIEILHQF |. ||. | || | .|. LIQMCWHPCPENRPDFDQIVTIL |
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| Kinase | AqueK489.AA | RIPK | 981-1013 | 40 | 9.5e-05 | 12.07 | In-house | 108-142 (290) | Show / Hide |
Range on Protein: 981-1013 Range on HMM: 108-142/290 Sequence Identity: 40% (14 aa) LRMRIVYQLASALKTLHSLK--IIHRNVCLENIIV || |.... ... ||| . |||| .||| | LRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILV |
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| Kinase | AqueK489.AA | Dicty5 | 1060-1080 | 47 | 0.000116 | 11.97 | In-house | 180-200 (260) | Show / Hide |
Range on Protein: 1060-1080 Range on HMM: 180-200/260 Sequence Identity: 47% (10 aa) YDQRADVFSFAFTSYEILTRK |.| .||.||. .|..||| YHQKCDVYSFGIVLWEMFTRK |
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| Kinase | AqueK489.AA | Jak | 1118-1139 | 36 | 0.000329 | 10.96 | In-house | 278-299 (299) | Show / Hide |
Range on Protein: 1118-1139 Range on HMM: 278-299/299 Sequence Identity: 36% (8 aa) KCWNNDPHKRPYFIEILHQFTK .||..||..|| | |. .. . QCWHYDPNQRPSFRTIIRDLNQ |
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| Kinase | AqueK489.AA | Dicty4 | 1059-1080 | 50 | 0.000334 | 10.11 | In-house | 193-214 (277) | Show / Hide |
Range on Protein: 1059-1080 Range on HMM: 193-214/277 Sequence Identity: 50% (11 aa) EYDQRADVFSFAFTSYEILTRK .|.. |||.||. .|||||. PYNEKADVYSFGIVLWEILTRQ |
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| Kinase | AqueK489.AA | Pkinase | 984-1004 | 42 | 0.00377 | 12.22 | Pfam | 112-132 (293) | Show / Hide |
Range on Protein: 984-1004 Range on HMM: 112-132/293 Sequence Identity: 42% (9 aa) RIVYQLASALKTLHSLKIIHR ...||....|. .|| .|||| FYMYQILRGLEYCHSMGIIHR |
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| Kinase | AqueK489.AA | Dicty5 | 980-1013 | 29 | 0.009712 | 5.25 | In-house | 104-137 (260) | Show / Hide |
Range on Protein: 980-1013 Range on HMM: 104-137/260 Sequence Identity: 29% (10 aa) FLRMRIVYQLASALKTLHSLKIIHRNVCLENIIV |... . | ... ||| |||| . |. . FQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLI |
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| Kinase | AqueK489.AA | MLK | 975-1004 | 30 | 0.019257 | 4.44 | In-house | 119-151 (291) | Show / Hide |
Range on Protein: 975-1004 Range on HMM: 119-151/291 Sequence Identity: 30% (10 aa) ISVSPFLRMRIVYQLASALKTLHSLK---IIHR . ... . |.. .| |... |||.. |||| RVYDHDHAMNWALQCARGMHYLHSMAPKPIIHR |
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| Kinase | AqueK489.AA | Pkinase | 1115-1137 | 36 | 0.089876 | 7.35 | Pfam | 269-293 (293) | Show / Hide |
Range on Protein: 1115-1137 Range on HMM: 269-293/293 Sequence Identity: 36% (9 aa) LLDKCWNNDPHKRPYFIEILHQ--F ....|.. ||.||| . .||. | FIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | AqueK489.AA | Jak | 1058-1079 | 29 | 0.138733 | 1.63 | In-house | 202-224 (299) | Show / Hide |
Range on Protein: 1058-1079 Range on HMM: 202-224/299 Sequence Identity: 29% (7 aa) YEYDQRADVFSFA-FTSYEIL-TR |.. . .|..||. | .||. .. YLT-LAMDKWSFGRVTLWEICNCY |
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| Kinase | AqueK489.AA | MLK | 1060-1080 | 38 | 0.225982 | 0.68 | In-house | 213-233 (291) | Show / Hide |
Range on Protein: 1060-1080 Range on HMM: 213-233/291 Sequence Identity: 38% (8 aa) YDQRADVFSFAFTSYEILTRK |. .||.|.. .|.|||. YSEKCDVWSWGVVLWEMLTRE |
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