Gene AqueK436 (A.queenslandica)

AqueK436

Species: A.queenslandica
Alias: AqueK436
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK436.AA Protein None 861 None Fasta, JSON
AqueK436.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of AqueK436.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 AqueK436.AA SH2 499-572 45 1.4e-26 79.87 Pfam 1-81 (81) Show / Hide 
Range on Protein: 499-572
Range on HMM: 1-81/81
Sequence Identity: 45% (37 aa)

YYH-TVSRDEAEERLSQTGTQAGTFLIRESIS--GTNTLSVKGGV---TIRHYHIYIEKNK-YYIYPHVKFDSLNDLVHHY
.||  .|| |||..| ..| . ||||.||| |  |  ||||. .     ..||.|  ..|. |||.  .||.||..||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK436.AA SH2 497-578 39 5.8e-24 86.86 SMART 1-87 (87) Show / Hide 
Range on Protein: 497-578
Range on HMM: 1-87/87
Sequence Identity: 39% (35 aa)

YIYYH-TVSRDEAEERLSQTGTQAGTFLIRESIS--GTNTLSVKGGVTIRHYHIYIEK-NKYYIYP--HVKFDSLNDLVHHYMMKADG
. .||  .||.|||. | . | . |.||.|.| |  |  .|||. .  ..||.|  .. .||||     .||.|| .||.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK436.AA Src 608-858 39 4.5e-83 282.07 In-house 1-255 (255) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-255/255
Sequence Identity: 39% (100 aa)

IKFLQYIRAGHFGETWKGDCNGIGPVIIKTNIATDITQEAFIKEAIILVKLHHKNIISLYGVCTESYPFYIITEPIDQN-LRNYLI--NMTKSPTQVKLV
||... . .|.||| |.|  ||  .| .||  . .  .||| .|| |. || |.....|| ||..  |.||.||   .. |  ||     ...    .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAIQITDGMKYLAEQDYIHCDVRAENILIGDRYNTVKIANFHLAQHLN-GKKYYSIKKYDLLAYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKE
|.| |. .||.|| .. ||| | .| |.|.|.    .|.| | ||. .  ..  |. ..   . ..|||||    .| .||||||||||||.|. |.|. 
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN-VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYPGMTDEEVKELVSKGDYMPIPRDCPEPFKQ-LMMNCWKQNEDQRPNFKHIFDTL
|||||| .|| . |..|  || |. ||. . . .|. ||..  .||| |. ... |
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK436.AA SFK-Src 608-851 40 1e-81 241.84 In-house 1-248 (259) Show / Hide 
Range on Protein: 608-851
Range on HMM: 1-248/259
Sequence Identity: 40% (101 aa)

IKFLQYIRAGHFGETWKGDCNGIGPVIIKTNIATDITQEAFIKEAIILVKLHHKNIISLYGVCTESYPFYIITEPIDQ-NLRNYLIN-MTKSPTQVKLVD
|.  .   .| ||. |||  |.   | .||     . .| | .|| .. || | | | || |||   | ||||| .    |  || .   .| .  .|||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

IAIQITDGMKYLAEQDYIHCDVRAENILIGDRYNTVKIANFHLAQHLNGKKY-YSIKKYDLLAYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKEP
 | |.  || || .| ..| |  | |.|.||  |..|.. | ..  |  .   |  ..      .|||||    || ||||||||||||. |. | |  |
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDN-NVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIP

YPGMTDEEVKELVSK--GDYMPIPRDCPEPFKQLMMNCWKQNEDQRPNF
|||||  ||   | .  |  || |  ||. . ..|..||... | || |
YPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF
Kinase AqueK436.AA Pkinase_Tyr 608-858 36 2.7e-81 275.96 Pfam 1-270 (270) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-270/270
Sequence Identity: 36% (99 aa)

IKFLQYIRAGHFGETWKGDCN-----GIGPVIIKTN--IATDIT--QEAFIKEAIILVKL-HHKNIISLYGVCT-ESYP--FYIITEPIDQ-NLRNYLIN
|.|.. . .|.||| .|| ..     .  || .|.    |..    .|.|..|| |. .| ||.||..|||||| .. |   ||..|     .|..|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

M---TKSPTQVKLVDIAIQITDGMKYLAEQDYIHCDVRAENILIGDRYNTVKIANFHLAQHLNGKKYY-SIKKYDLLAYRWTAPEGHILNRLSIKSDVWS
     ...|   |.....|| .|| ||... .|| |..| |.|...   .|||. | ||  .  . ||   ..   |  .|.|||    .. ..||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGILLWELATKGKEP-YPGMTDEEVKELV-SKGDYMPIPRDCPEPFKQLMMNCWKQNEDQRPNFKHIFDTL
||.|.||. | |..| ||||..|||.|..  .|  ||.|..||..  .||. ||... ..|| |. |   |
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK436.AA TK 608-858 19 9.4e-77 256.66 In-house 1-486 (486) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-486/486
Sequence Identity: 19% (96 aa)

IKFLQYIRAGHFG---ETWKGDCNGIG--------------------------PVIIKTNIAT-DITQEAFIK--------------EAIILVKLH----
|.... . .|.||   | .||  .|..                          || .|.  .. . .||.|.               || .. ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIISLYGVCTES------------YPFYIITEPID-QN----LRNYLINMTKS--------------------------------------------
 |.||..||||||..             |..|..|  .  .    ||.|| .  .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------PTQVKLVDIAIQITDGMKYLAEQ------DYIHCDVRAENILIGDRYN----------TVKIANFH---
                               .|   |. .. || .|| ||...       ..| |. | |.|.|....          ..||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAQHLNGKKYYSIKK------------------------YDLLAYRWTAPEGHI---------LNRLSIKSDVWSFGILLWELATKGKEPYPG-M
     ||  .. ...|  |.                         . |  ||.|||             .. ..||||||||.|.||. | |.|||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------EEVKELVSKG--------------DYMPIPRDCP--------------EPFKQLMMNCWKQNEDQRPNFKHIFDTL
..         .|| |.. .|                || | .||              | . .||. ||. . ..||.|. . . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK436.AA TyrKc 608-858 33 1.6e-75 258.1 SMART 1-280 (280) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-280/280
Sequence Identity: 33% (95 aa)

IKFLQYIRAGHFGETWKGDCNGIGPVIIKTNIATDITQEAFIKEAIILVKL--HHKNIISLYGVCTES-------YPFYIITEPIDQ-NLRNYLINMTKS
|.... .  |.||| .||  .   .| .|.  .    .|.|..|| |. ||  ||.||. ||||||..        | .|..|  .  .|..|| .  . 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PTQVKLVDIAIQITDGMKYLAEQDYIHCDVRAENILIGDRYNTVKIANFHLAQHLNGK-------KYYSI----KKYDLLAYRWTAPEGHILNRLSIKSD
 .  .|.....|| .|| ||... .|| |  | |.|.|... ||||. | |.  .  .       .||.      . ..| .||.|||    .. ..|||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGILLWELATKGKEPYPG-----MTDEEVKELVSKGDYMPIPRD--------CPEPFKQLMMNCWKQNEDQRPNFKHIFDTL
|||||...||. | |..||||     |...|| |.| .|..||.| .        ||.   |.|  ||. . ..||.|. | . .
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK436.AA Frk 608-851 41 4.4e-74 252.42 In-house 1-249 (260) Show / Hide 
Range on Protein: 608-851
Range on HMM: 1-249/260
Sequence Identity: 41% (103 aa)

IKFLQYIRAGHFGETWKGDCNGIGPVIIKTNIATDITQEAFIKEAIILVKLHHKNIISLYGVCTESYPFYIITEPIDQN-LRNYLINMTKSPTQVKL---
|.... . .| ||| | |  |   || .||  .  .  . |..|| |. || |  .|.|| |||   | ||||| . .. | .||  ...   |...   
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQITDGMKYLAEQDYIHCDVRAENILIGDRYNTVKIANFHLAQHLNGKKY--YSIKKYDLLAYRWTAPEGHILNRLSIKSDVWSFGILLWELATKG
||.| |.  || || .| ||| |. | |.|.|.  | .||| | ||  |   .   |  .    .  .|||||    |. .|||||||||||| |. | |
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEH-NICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYG

KEPYPGMTDEEVKELVSKGDYMPIPRDCPEPFKQLMMNCWKQNEDQRPNF
. ||||||. || . |..|  || | .||. . ..|..||... ..|| |
RMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTF
Kinase AqueK436.AA SrcA 608-858 41 2e-70 221.62 In-house 1-250 (250) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-250/250
Sequence Identity: 41% (106 aa)

IKFLQYIRAGHFGETWKGDCNGIGPVIIKTNIATDITQEAFIKEAIILVKLHHKNIISLYGVCTESYPFYIITEPIDQ-NLRNYLINMTKSPTQV-KLVD
|.  . .  | ||| | |  ||   | |||     .  |||..|| |. ||.|  .. || |  |  | ||.|| . .  |  .| . .    .. .|||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

IAIQITDGMKYLAEQDYIHCDVRAENILIGDRYNTVKIANFHLAQHLNGKKYYSIKKYDLLAYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKEPY
.| |. .|| |.    ||| |.|| |||.|..    ||| | ||  ..    |  ..      .|||||  .  |  |||||||||||| || |||. ||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENL-ICKIADFGLARLIEDNE-YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY

PGMTDEEVKELVSKGDYMPIPRDCPEPFKQLMMNCWKQNEDQRPNFKHIFDTL
||| . || | | .|  || |.||||   .||. ||... . || |  .   |
PGMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK436.AA Src-Echino1 608-858 38 2.3e-67 230.1 In-house 1-252 (252) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-252/252
Sequence Identity: 38% (98 aa)

IKFLQYIRAGHFGETWKGDCNGIGPVIIKTNIATDITQEAFIKEAIILVKLHHKNIISLYGVCTESYPFYIITEPIDQ-NLRNYLINMTKSPTQV-KLVD
 .. . |  ||.|| |||  ||  || .||     ... .|. || .. |. |..|. .| || .. | ||.|| . . ||..|| .     ... .|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAIQITDGMKYLAEQDYIHCDVRAENILIGDRYNTVKIANFHLAQHLNGKKYYSIKKYDLLAYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKEPY
.  .|  || || .....| |. | |.|.| . | .|||.| ||. .. |  |  |.   |  .|||||  .  |  |||||||||||. |. | |. ||
MGAHIASGMDYLGSKNVVHRDLAARNVLVG-KGNVCKIADFGLARMMQ-KDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPY

PGMTDEEVKELVSKGDYMPIPRDCPEPFKQL-MMNCWKQNEDQRPNFKHIFDTL
|||.. || . | .|  || . .||.   .. || || ..  ||| |... | .
PGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK436.AA TK-Unique 608-858 30 1.4e-64 220.9 In-house 1-294 (294) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-294/294
Sequence Identity: 30% (89 aa)

IKFLQYIRAGHFGETWKGDCNGIG-------PVIIKTNI--ATDITQEAFIKEAIILVKLH-HKNIISLYGVCTESY-PFYIITEPIDQN-LRNYLI---
......|  | ||. |.|.  ||         |..|..   ||| .. .| ||. .. .|  |.||....|.||.|  |..|| |.. .  |..||    
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-------------------NMTKSPTQVK---LVDIAIQITDGMKYLAEQDY--IHCDVRAENILIGDRYNTVKIANFHLAQHLN-GKKYYSIKKYDLLA
                   ....... ..   |. .|.||  ||.|||.| .  .| |. | |.|... ....||..| .| ... ...| .....  . 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE-DKVCKICDFGMARDVYTNGVYSMMCSQGRIP

YRWTAPEGHI--LNRL-SIKSDVWSFGILLWELATKGKEPYPGMTDEEVKELVSKGDYMPIPRDC-PEPFKQLMMNCWKQNEDQRPNFKHIFDTL
.|| |||      .   ..||||||||.|.||..| |. ||||| .... |.. .|. || |  | .. . .|| .||. ....||.|  | . |
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK436.AA UTK 608-858 29 2.8e-63 215.34 In-house 1-296 (296) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-296/296
Sequence Identity: 29% (87 aa)

IKFLQYIRAGHFGETWKGDCNGIG------PVIIKTNI--ATDITQEA----FIKEAI---ILVKLH-HKNIISLYGVCTESYPFYIITEPID-QNLRNY
..... ...|.|||  |.. . .        | .|..   |.. ....    |..||    .. ..| | |.. |.|||| . |..|.||     .||.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LINMTK----SPTQVK---LVDIAIQITDGMKYLAEQDYIHCDVRAENILIGDR------YNTVKIANFH---LAQHLNG--------KKYYSIKK-YDL
| . ..     |....   ... | .| .|| ||... ..|.|. | |.|...        ...|||.|    ..  .|.          ||. .   | 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LAYRWTAPEGHILN-RLSIKSDVWSFGILLWELATKGKEPYPGMTDEEVKELVSKGD--YMPIPRDCPEPFKQLMMNCWKQNEDQRPNFKHIFDTL
.. ||.|||  . . | ..||||||||...||. | |. |||||....| . |..|.   || |.|||.|  .||. ||... . ||.|. . ...
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK436.AA Abl 608-858 37 7.1e-62 205.02 In-house 1-252 (252) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-252/252
Sequence Identity: 37% (94 aa)

IKFLQYIRAGHFGETWKGDCNGIGPVI-IKTNIATDITQEAFIKEAIILVKLHHKNIISLYGVCTESYPFYIITEPIDQ-NLRNYLINMTKSP-TQVKLV
|   . .  | .|| ..|     . .. .||     .  . |.||| |. ...|.|.. | ||||   ||||||| . . || .|| .  ..  . | |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DIAIQITDGMKYLAEQDYIHCDVRAENILIGDRYNTVKIANFHLAQHLNGKKYYSIKKYDLLAYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKEP
 .| ||. ||.|| ....|| |. | | |.|.  . ||.| | ||  ...   |  .       .|||||.   |. |.||||| ||.||||.|| |  |
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEH-HIVKVADFGLARMMKD-DTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSP

YPGMTDEEVKELVSKGDYMPIPRDCPEPFKQLMMNCWKQNEDQRPNFKHIFDTL
|||.  ..| ... ||  |  |. ||.   .|| .||. ..  || ||.|  ..
YPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK436.AA Src-Unclassified 608-858 35 5e-60 204.51 In-house 1-284 (284) Show / Hide 
Range on Protein: 608-858
Range on HMM: 1-284/284
Sequence Identity: 35% (100 aa)

IKFLQYIRAGHFGETWKGDCNGIGPVIIKTNIAT---DITQEAFI--------KEAIILVKLHHKNIISLYGVCTESYPFYIITE-PIDQNLRNYLINMT
.. |  .  | ||| |.|   |.  | .||  .        |||         .|| |. |. | |.. ||.||..  |.|||||  |   |  .|   .
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

-KSPTQVKL------------VDIAIQITDGMKYLAEQDYIHCDVRAENILIGDRYN----TVKIANFHLA-QHLNGKKYYSIKKYDLLAYRWTAPEGHI
 . .    .            |||| |.  || || .  |.| |  | |.|||.        ||.. | ||   | .   |  ..   .   |.|||  |
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

LNRLSIKSDVWSFGILLWELATKGKEPYPGMTDEEVKELVSKGDYMPIP--RDCPEPFKQ-LMMNCWKQNEDQRPNFKHIFDTL
    ||||||||.||||||..|||. |||||  .|| | |. |  || |  . ||.   . .|  || .  ..|| |   .  .
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK436.AA S_TKc 608-860 22 1.8e-26 95.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 608-860
Range on HMM: 1-231/231
Sequence Identity: 22% (60 aa)

IKFLQYIRAGHFGETWKGDCNG-IGPVIIKTNIATDITQEAFIKEAIILVKLHHKNIISLYGVCTESYPFYIITEPIDQ---NLRNYLINMTKSP-----
 ..|. |  | ||. .|.  ..    | ||         | ...|  || | ||.||. ||.|. .   .|...| .|.   .|. |. .. . .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TQVKLVDIAIQITDGMKYLAEQDYIHCDVRAENILIGDRYNTVKIANFHLAQHLNGKKYYSIKKYDLLAYRWTAPEGHILNRLSI-KSDVWSFGILLWEL
.      .. || ....|. ..  ||.|.  ||||. .   ..||. | || .|         .       . |||  .|   .  |.|.||.|..|.|.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL---------TTFCGTPWYMAPE--VL-GYGKCKCDWWSCGCILYEM

ATKGKEPYPGMTDEEVKELVSKGDYMPIPRDCPEPFKQLMMNCWKQNEDQRPNFKHIFD-------TLLT
.. |. |.|  ..... ...            ....|.....|.. . ..||    ..            
LC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK436.AA Pkinase 645-858 20 6.4e-20 71.52 Pfam 42-293 (293) Show / Hide 
Range on Protein: 645-858
Range on HMM: 42-293/293
Sequence Identity: 20% (54 aa)

QEAFIK--EAIILVKLHHKNIISLYGVCTESYPFYIITEPIDQ-----NLRNYLI-NMTKSP--TQVKLVDIAIQITDGMKYLAEQDYIHCDVRAENILI
... ..  |. |. .|.|.||. ||......   |...|  .       |  |.   . ..   .   . ... ||  |..|. ..  ||.|.  |||||
DQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI

GDRYNT---VKIANFHLAQHLNGKKYYSIKKYDLLA--YRWTAPEGHI-LNRLSIKSDVWSFGILLWELATKGKEPYPGM----TDEEVKELVSKGDYMP
 .....   |||. | || ...   | .   .. ..  ... ||| .   .  . |.|.||.|..|.|... |. |.||     .  . .... .  . |
DNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPP

IPRDCP-----------------------EPFKQLMMNCWKQNEDQRPNFKHIFDT--L
...|.|                       |..|... .|....  .||....|.    .
LHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF