Gene AqueK428 (A.queenslandica)

AqueK428

Species: A.queenslandica
Alias: AqueK428
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK428.AA Protein None 1138 None Fasta, JSON
AqueK428.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of AqueK428.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Death AqueK428.AA Death 32-108 21 0.000777 15.14 Pfam 13-87 (87) Show / Hide 
Range on Protein: 32-108
Range on HMM: 13-87/87
Sequence Identity: 21% (17 aa)

PEAKWFEFGLNLGLLYPTLEAIDA-NHRGNTSRCLMECLSKWLSKADENVYPPTWQTLASALRKLEAKAVAENIEKTM
| ..| ...  ||. .  .. |   .......   .. | ||  .   .    | ..|..||||..   .||.|.  .
PGKDWRRLARKLGMSDNEIDQIEHDQNPHDLRSQTYQMLWKWEQR---HGKNATVDHLIEALRKMGRRDCAEKIQSWL
SH3_2 AqueK428.AA SH3_2 598-620 18 23.528681 0.63 Pfam 1-32 (68) Show / Hide 
Range on Protein: 598-620
Range on HMM: 1-32/68
Sequence Identity: 18% (6 aa)

ICVAQDDYSE----TT-----ISFKKGELLQL
 ...  ||      .      ..||||... .
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKV
SH3 AqueK428.AA SH3 704-763 33 3.2e-15 57.81 SMART 1-58 (58) Show / Hide 
Range on Protein: 704-763
Range on HMM: 1-58/58
Sequence Identity: 33% (20 aa)

KLFKASYNFEAQTSDNLTLKKGEVVKVVKYHEDDERWWYMHSLHTDEEGYVPINYITPIE
. ..| |...||..| |..|||... |.. .  |. ||.    .| .||..| ||...|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKD--DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK428.AA SH3_1 707-756 34 5.4e-11 40.15 Pfam 1-49 (49) Show / Hide 
Range on Protein: 707-756
Range on HMM: 1-49/49
Sequence Identity: 34% (17 aa)

KASYNFEAQTSDNLTLKKGEVVKVVKYHEDDERWWYMHSLHTDEEGYVPI
.| | ..||..| |..|||....|..  .|   ||   .. | .||..| 
VALYDYQAQQPDELSFKKGDIIHVIEKSDD-WDWWKGRCNNTGQEGWFPS
SH3_2 AqueK428.AA SH3_2 705-762 17 1.2e-07 29.69 Pfam 1-68 (68) Show / Hide 
Range on Protein: 705-762
Range on HMM: 1-68/68
Sequence Identity: 17% (12 aa)

LFKASYNFEA-QTSDN-----LTLKKGEVVKVV--KYHEDDERWWYMHSL-HTDEE--GYVPINYITPI
....  .... .  .      |..|||.|.||   . ...|  ||. .    . ..  |..|.... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWD-NWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK428.AA SH2 775-848 45 3e-25 75.97 Pfam 1-81 (81) Show / Hide 
Range on Protein: 775-848
Range on HMM: 1-81/81
Sequence Identity: 45% (37 aa)

YYH-TVSRDEAEERLSQANTQSGTFLIRESIS--GMNTLSVKDEV---TIRHYHIYIENNK-YYMNPRVKFVSLNDLVHHY
.||  .|| |||..| .   . ||||.||| |  |  ||||.|.     ..||.|  ..|. ||.  |.|| ||..||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK428.AA SH2 773-854 38 6.8e-23 83.3 SMART 1-87 (87) Show / Hide 
Range on Protein: 773-854
Range on HMM: 1-87/87
Sequence Identity: 38% (34 aa)

YIYYH-TVSRDEAEERLSQANTQSGTFLIRESIS--GMNTLSVKDEVTIRHYHIYIEN-NKYYMNP--RVKFVSLNDLVHHYMMKADG
. .||  .||.|||. | .   . |.||.|.| |  |  .|||...  ..||.|  .. .|||     |.|| || .||.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK428.AA Src 884-1131 40 2.3e-96 326.46 In-house 1-255 (255) Show / Hide 
Range on Protein: 884-1131
Range on HMM: 1-255/255
Sequence Identity: 40% (104 aa)

IEFEQCINAGQFGETWKGNCKGKGPVIIKTNIATNITQETFIKEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPMNEN-LKDYLT----TNNPTPAELV
| ... . .||||| |.|  .|. .| .||  . .  .| | .|| .. || |.....|| ||... |.||||| |... | |||     . .    .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLN--SNKYWIVKEGTTLAFKWTAPECHTSKQLSIKSDVWSFGILLWELATKGKI
|.| || .|| ||... ||| ||.| |.| |. | .|.| | ||. .    . |   ..|  .  ||||||. .  . .||||||||||||.|. |.|..
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY-CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYPGMTNAQVQESVSRGYHMPIPQDCTEPFKQ-LMINCWKRSEDKRPSFKKILVYL
|||||||..| . |.|||.|| |. | . . . .|  ||... ..|| |. .  .|
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK428.AA SFK-Src 884-1135 41 6.5e-93 275.65 In-house 1-259 (259) Show / Hide 
Range on Protein: 884-1135
Range on HMM: 1-259/259
Sequence Identity: 41% (107 aa)

IEFEQCINAGQFGETWKGNCKGKGPVIIKTNIATNITQETFIKEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPM-NENLKDYLTT---NNPTPAELVD
|. |.   .||||. |||   ..  | .||     . .| | .|| |. || | | | || |||   | ||.|| | .  | |||        .   |||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

IAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLNSNKY-WIVKEGTTLAFKWTAPECHTSKQLSIKSDVWSFGILLWELATKGKIPY
 | ||  || || .| ..| || | |.| || |..|.. | ..  |  .   .  .||     ||||||  .  . ||||||||||||. |. | | |||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMTNAQVQESVSR--GYHMPIPQDCTEPFKQLMINCWKRSEDKRPSFKKILVYLSHTH
|||||. |   | |  || || |. | . . ..|..||.   | || |   .. .    
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK428.AA Pkinase_Tyr 884-1131 38 2.4e-85 289.66 Pfam 1-270 (270) Show / Hide 
Range on Protein: 884-1131
Range on HMM: 1-270/270
Sequence Identity: 38% (105 aa)

IEFEQCINAGQFGETWKGNCK-----GKGPVIIKTN--IATNIT--QETFIKEAYVLLKL-YHKNIISLYGVCT-EDYP--FYIVTEPMNE-NLKDYLTT
|.| . . .|.||| .|| .|     .| || .|.    |.     .| |..|| .. .| .|.||..|||||| .. |   |||.| |   .|.||| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N-----NPTPAELVDIAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHL-NSNKYWIVKEGTTLAFKWTAPECHTSKQLSIKSDVWSF
.     ..|. .|.....|. .|| || .. .|| ||.| |.|... |.|||. | ||  . |   |  ...|. |  ||.||||   .  ..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWELATKGKIP-YPGMTNAQVQESV-SRGYHMPIPQDCTEPFKQLMINCWKRSEDKRPSFKKILVYL
|.|.||. | |..| ||||.|..| | .  .|| ||.|..|...  .||  ||.   ..||.|. |.  |
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK428.AA Frk 884-1135 41 7.8e-82 278.18 In-house 1-260 (260) Show / Hide 
Range on Protein: 884-1135
Range on HMM: 1-260/260
Sequence Identity: 41% (107 aa)

IEFEQCINAGQFGETWKGNCKGKGPVIIKTNIATNITQETFIKEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPMNEN-LKDYLT-----TNNPTPAEL
|.. . . .||||| | |    . || .||  .  .  . |..|| .. || |  .|.|| ||| . | ||.|| | .. |..||       ..    .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLNSNKY--WIVKEGTTLAFKWTAPECHTSKQLSIKSDVWSFGILLWELATKGK
||.| ||  || || .| ||| || | |.|.|. | .||| | ||  |  ..   .  . |  .  ||||||   ... .|||||||||||| |. | |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

IPYPGMTNAQVQESVSRGYHMPIPQDCTEPFKQLMINCWKRSEDKRPSFKKILVYLSHTH
.||||||||.| . |..|| || | .| . . ..|..||.   .||| |  .   | .  
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK428.AA SrcA 884-1131 45 5.4e-81 255.59 In-house 1-250 (250) Show / Hide 
Range on Protein: 884-1131
Range on HMM: 1-250/250
Sequence Identity: 45% (114 aa)

IEFEQCINAGQFGETWKGNCKGKGPVIIKTNIATNITQETFIKEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPMNE-NLKDYLTTNNPTP---AELVD
|. |. .  |.||| | |   |.  | |||     .  |.|..|| .. || |  .. || |  |. | ||||| |..  | |.|  ..       .|||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

IAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLNSNKYWIVKEGTTLAFKWTAPECHTSKQLSIKSDVWSFGILLWELATKGKIPYP
.| || .|| |.    ||| |||| ||| |..   ||| | ||  .. | |   . |.    ||||||        |||||||||||| || |||..|||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMTNAQVQESVSRGYHMPIPQDCTEPFKQLMINCWKRSEDKRPSFKKILVYL
|| |  | | | |||||| |||| |   .||. ||..  . || |  .  .|
GMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK428.AA TK 884-1131 20 7e-75 250.28 In-house 1-486 (486) Show / Hide 
Range on Protein: 884-1131
Range on HMM: 1-486/486
Sequence Identity: 20% (99 aa)

IEFEQCINAGQFG---ETWKGNCKGKG--------------------------PVIIKTNIAT-NITQETFIK--------------EAYVLLKLY----
|.... . .||||   | .||  .|..                          || .|.  .. . .|| |.               || .. ..     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIISLYGVCTED------------YPFYIVTEPMN-EN----LKDYLTTN-----------------------------------------------
 |.||..||||||..             |..||.| |.  .    |.||| ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------NPTPAELVDIAIQVTDGMIYLGEQ------DYIHCDLRAINILLGDRNT-----------VKIANFH---
                              ..|...|. .. |. .|| || ..       ..| || | |.|.|..|.           .||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAQHLNSNKYWIVKE------------------------GTTLAFKWTAPECHTSKQ---------LSIKSDVWSFGILLWELATKG-KIPYPGM
     ||  ..|...  .|.                        |. | ..|.|||| ....          ..||||||||.|.||. | | . .|.||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------AQVQESVSRG--------------YHMPIPQDCT--------------EPFKQLMINCWKRSEDKRPSFKKILVYL
.|         ..| | . ||              . || |..|.              | . .||  ||..  ..||.|. .. .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK428.AA TyrKc 884-1131 35 3.3e-74 253.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 884-1131
Range on HMM: 1-280/280
Sequence Identity: 35% (100 aa)

IEFEQCINAGQFGETWKGNCKGKGPVIIKTNIATNITQETFIKEAYVLLKL--YHKNIISLYGVCTED-------YPFYIVTEPM-NENLKDYLTTNN--
|.... .  |.||| .||  |   .| .|.  .    .| |..|| .. ||   |.||. ||||||..        | .||.| | . .|||||  .   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PTPAELVDIAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLNSN-------KYWIVKE--GTT--LAFKWTAPECHTSKQLSIKSDV
 ....|.....|. .|| || .. .|| || | |.|.|...||||. | |.  . .        .|  .||  |.   |  .|.||||   .  ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELATKGKIPYPG-----MTNAQVQESVSRGYHMPIPQD--------CTEPFKQLMINCWKRSEDKRPSFKKILVYL
||||...||. | |. ||||     |.|..| | | .|| ||.|..        |..   |.|  ||..  ..||.|. |  ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK428.AA Src-Echino1 884-1131 39 1.8e-73 250.41 In-house 1-252 (252) Show / Hide 
Range on Protein: 884-1131
Range on HMM: 1-252/252
Sequence Identity: 39% (100 aa)

IEFEQCINAGQFGETWKGNCKGKGPVIIKTNIATNITQETFIKEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPM-NENLKDYLTTNNPT---PAELVD
 .... |  |..|| |||  .|  || .||     ...  |. || |. |. |..|. .| || .  | ||||| | | ||.|||  ..      ..|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLNSNKYWIVKEGTTLAFKWTAPECHTSKQLSIKSDVWSFGILLWELATKGKIPYP
.  ..  || |||.....| || | |.|.|. | .|||.| ||. .. . | . |.|  |  ||||||     .  |||||||||||. |. | |..|||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVY-CGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMTNAQVQESVSRGYHMPIPQDCTEPFKQL-MINCWKRSEDKRPSFKKILVYL
||.| .| . | ||| || ...|..   .. |. || .   .|| |. .  ..
GMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK428.AA SrcB 884-1132 41 1.1e-72 245.25 In-house 1-251 (251) Show / Hide 
Range on Protein: 884-1132
Range on HMM: 1-251/251
Sequence Identity: 41% (104 aa)

IEFEQCINAGQFGETWKGNCKGKGPVIIKTNIATNITQETFIKEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPMNE-NLKDYLTTNNPTPAE---LVD
. ... . |||||| | |  ...  | .||     .  | |..|| |. .| |. .. || | | . | ||.|| |..  | |.| |.. .  .   |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLNSNKYWIVKEGTTLAFKWTAPECHTSKQLSIKSDVWSFGILLWELATKGKIPYP
.. |...|| |. .. ||| |||| |||  .    ||| | ||  ...| |   .||     ||||||        |||||||||||| |. | |.||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMTNAQVQESVSRGYHMPIPQDCTEPFKQLMINCWKRSEDKRPSFKKILVYLS
||||..| ....||| || |. | |   ..|. |||   . || |  .   | 
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK428.AA Src-Unclassified 893-1131 37 6.7e-69 235.21 In-house 10-284 (284) Show / Hide 
Range on Protein: 893-1131
Range on HMM: 10-284/284
Sequence Identity: 37% (104 aa)

GQFGETWKGNCKGKGPVIIKTNIAT---NITQETFI--------KEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPM-NENLKDYLTTNN---PTPAEL
||||| |.|  .||  | .||  .        | |         .|| .. |. | |.. ||.||... |.||.|| | |  | ..| .     .   ..
GQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGGGQYLHIQDM

------------VDIAIQVTDGMIYLGEQDYIHCDLRAINILLGDRN-----TVKIANFHLA--QHLNSNKYWIVKEGTTLAFKWTAPECHTSKQLSIKS
            |||| ||  || || .  |.| || | |.| |. |      ||.. | ||         | . . |  .  ||.|||| .    ||||
SEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNY-CMRTGAMFPWKWMAPECFIYGNFSIKS

DVWSFGILLWELATKGKIPYPGMTNAQVQESVSRGYHMPIP--QDCTEPFKQ-LMINCWKRSEDKRPSFKKILVYL
||||.||||||..|||..||||| |  | | |.||| || |  . | .   . .|  ||    ..|| |     |.
DVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK428.AA SRM 886-1132 42 1.3e-68 228.64 In-house 1-253 (253) Show / Hide 
Range on Protein: 886-1132
Range on HMM: 1-253/253
Sequence Identity: 42% (108 aa)

FEQC--INAGQFGETWKGNCKGKGPVIIKTNIATN-ITQETFIKEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPMNE-NLKDYLTTNNPTP---AELV
|  |    .| ||| | |  ||. .| ||     | . |... ||   . || || ||.|. ||.   | ||.|| |   ||  || . .       .|.
FTLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLL

DIAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLNSNKYWIVKEGTTLAFKWTAPECHTSKQLSIKSDVWSFGILLWELATKGKIPY
|.| ||  || || || ||| || | |.| || |. |.. | ||  .    |    .     .||||||       |.|||||||||||.|. |.| .||
DFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHD-HNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPY

PGMTNAQVQESVSRGYHMPIPQDCTEPFKQLMINCWKRSEDKRPSFKKILVYLS
|||||      ..||| || |  |      ||. ||.|. ..||.||     |.
PGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase AqueK428.AA Abl 884-1131 38 4.7e-68 225.99 In-house 1-252 (252) Show / Hide 
Range on Protein: 884-1131
Range on HMM: 1-252/252
Sequence Identity: 38% (97 aa)

IEFEQCINAGQFGETWKGNCKGKGPVI-IKTNIATNITQETFIKEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPM-NENLKDYLTTNNPT---PAELV
|  .. .  ||.|| ..|  |  . .. .||    ..  . |.||| .. .. |.|.. | |||| . ||||.|| | . || |||  .. .   .  |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DIAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLNSNKYWIVKEGTTLAFKWTAPECHTSKQLSIKSDVWSFGILLWELATKGKIPY
 .| |.. || || ....|| || | | |.|. . ||.| | ||  .. . |   . |     ||||||    .. |.||||| ||.||||.|| |  ||
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

PGMTNAQVQESVSRGYHMPIPQDCTEPFKQLMINCWKRSEDKRPSFKKILVYL
||.   .| . . .|| |  |. | .   .|| .||. |.  |||||.|   .
PGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK428.AA S_TKc 884-1131 22 1.4e-30 108.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 884-1131
Range on HMM: 1-231/231
Sequence Identity: 22% (61 aa)

IEFEQCINAGQFGETWKGNCKG-KGPVIIKTNIATNITQETFIKEAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPMNE---NLKDYLTTNNP-------
 |. . |  | ||. .|.  |. .  | ||         |....|  .| |  |.||. ||.|. .   .|.|.| ..    .|.||.  ...       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TPAELVDIAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTVKIANFHLAQHLNSNKYWIVKEGTTLAFKWTAPECHTSKQLSI-KSDVWSFGILLWELA
.. .   .. |. ... |. ..  ||.||   |||| .  ..||. | || .|                 . |||     . .  |.|.||.|..|.|..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TKGKIPYPGMTNAQVQESVSRGYHMPIPQDCTEPFKQLMINCWKRSEDKRPSFKKILV---------YL
. |. |.|  . ... . .            ....|... .|...  .|||.  ..|          ..
C-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK428.AA Pkinase 884-1017 23 8.1e-13 46.41 Pfam 1-154 (293) Show / Hide 
Range on Protein: 884-1017
Range on HMM: 1-154/293
Sequence Identity: 23% (36 aa)

IEFEQCINAGQFGETWKGNCKGKG-PVIIKTNIATNITQETFIK-----EAYVLLKLYHKNIISLYGVCTEDYPFYIVTEPMNE-----NLKDYLT---T
......| .| ||. .|.  || |  | .|.    ..  .  .      |......| |.||. ||......   |.|.| ..       |.||..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NNP--TPAELVDIAIQVTDGMIYLGEQDYIHCDLRAINILLGDRNTV----KIA
..   .. |. ... |.  |. |. ..  ||.||   |||. .....    ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKIC
Kinase AqueK428.AA Pkinase 1045-1131 21 1.6e-12 45.4 Pfam 179-293 (293) Show / Hide 
Range on Protein: 1045-1131
Range on HMM: 179-293/293
Sequence Identity: 21% (25 aa)

APECHT-SKQLSIKSDVWSFGILLWELATKGKIPYPGM----TNAQVQESVSRGYHMPIPQDCT-----------------------EPFKQLMINCWKR
||| .  ..  . |.|.||.|..|.|... |. |.||     . .  .. . |  . |.. |.                        |..|... .|...
APEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

SEDKRPSFKKILVY--L
   |||... ||    .
DPKKRPTAEQILQHPWF