Gene AqueK427 (A.queenslandica)

AqueK427

Species: A.queenslandica
Alias: AqueK427
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK427.AA Protein None 617 None Fasta, JSON
AqueK427.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of AqueK427.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 AqueK427.AA SH3 179-237 27 2e-06 28.66 SMART 1-58 (58) Show / Hide 
Range on Protein: 179-237
Range on HMM: 1-58/58
Sequence Identity: 27% (16 aa)

KLFMAINNFEGLSPHDLTLKKGDLFKVFKYHEDDEWWYMHSLHTDSKGYVQINCILPIE
. . |. .... .| .|..|||| . | . . ||.||.    .|  .|..  |.. .|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 AqueK427.AA SH3_2 180-236 16 4e-06 24.41 Pfam 1-68 (68) Show / Hide 
Range on Protein: 180-236
Range on HMM: 1-68/68
Sequence Identity: 16% (11 aa)

LFMAINNFEG-LSPHD-----LTLKKGDLFKVF--KYHEDDEWWYMHSL-HTDSK--GYVQINCILPI
.. .. ....  .. .     |..||||..||.  . ...|.||. .    .  .  |.. .... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH3_1 AqueK427.AA SH3_1 182-215 32 4e-06 23.91 Pfam 1-34 (49) Show / Hide 
Range on Protein: 182-215
Range on HMM: 1-34/49
Sequence Identity: 32% (11 aa)

MAINNFEGLSPHDLTLKKGDLFKVFKYHEDDEWW
 |.  ... .| .|..|||| ..| .  .|..||
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWW
SH2 AqueK427.AA SH2 249-324 46 1.9e-31 94.18 Pfam 2-81 (81) Show / Hide 
Range on Protein: 249-324
Range on HMM: 2-81/81
Sequence Identity: 46% (37 aa)

YYYVVSRNEAEKRLSQTDTQAGAFLIRDSESNPGQYTLSLNDGA---TIRQYRIRIEFNK-YYIFSRVKFNSLNDLVHHY
|.  .||.|||..| ..  . |.||.|.|||.||.||||. |.     .. |||. . |. |||. |.||.||..||.||
YHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK427.AA SH2 246-330 44 1.7e-24 88.65 SMART 1-87 (87) Show / Hide 
Range on Protein: 246-330
Range on HMM: 1-87/87
Sequence Identity: 44% (39 aa)

KYVYYYVVSRNEAEKRLSQTDTQAGAFLIRDSESNPGQYTLSLNDGATIRQYRIRIEF-NKYYIFS--RVKFNSLNDLVHHYMMKADG
   |.  .|| |||. | .   . |.||.||||||||.|.||. ..  .. |||| .  .||||    |.||.|| .||.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK427.AA Src 360-607 40 2e-88 300.04 In-house 1-255 (255) Show / Hide 
Range on Protein: 360-607
Range on HMM: 1-255/255
Sequence Identity: 40% (104 aa)

INFSQCIHVGHFGETWKGYCKGKGTVIIKTNIATDITQETFVKEAIILEKLNHKNIISLYGVCTESYPFYIVTE-PINGNLKNYLT----TNNPTPAELV
| . . .  |.||| |.|| .|.  | .||  . .  .| | .|| |. || |.....|| ||..  |.|||||   .|.|  ||     . .    .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQYLN--GNKYWNVKKETRLAIKWTAPEGYTAEQLSIKSDVWSFGILLWELVTKGDL
|.| || .||.||... ||| ||.| |.| |..| .|.| |  |. .    . | . ... .. |||||||  .  . .||||||||||||.|.||.|  
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY-CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYRGMTDKEVKEAVQRGYRMPIPWTSPVPFYR-LIINCWNYKEDERPNFWNIFDVL
||.||| .|| ..|.|||||| | . |  .|  ..  ||. . ..|| |  ....|
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK427.AA SFK-Src 360-600 41 4.8e-86 254.91 In-house 1-248 (259) Show / Hide 
Range on Protein: 360-600
Range on HMM: 1-248/259
Sequence Identity: 41% (102 aa)

INFSQCIHVGHFGETWKGYCKGKGTVIIKTNIATDITQETFVKEAIILEKLNHKNIISLYGVCTESYPFYIVTEPI-NGNLKNYLTT---NNPTPAELVD
|   .    | ||. |||   ..  | .||     . .| | .|| .. || | | | || |||   | ||.|| . .| |  ||        .   |||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

IAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQYLNGNKY-WNVKKETRLAIKWTAPEGYTAEQLSIKSDVWSFGILLWELVTKGDLPY
 | ||  || || .| ..| || | |.| || |..|.. |  .  |  .   .  ..  .  |||||||  .  . ||||||||||||. |.|| |  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

RGMTDKEVKEAVQR--GYRMPIPWTSPVPFYRLIINCWNYKEDERPNF
 ||| .||   | |  ||||| |   |  .| . ..||  . |.|| |
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF
Kinase AqueK427.AA Pkinase_Tyr 360-607 37 8.5e-78 264.11 Pfam 1-270 (270) Show / Hide 
Range on Protein: 360-607
Range on HMM: 1-270/270
Sequence Identity: 37% (102 aa)

INFSQCIHVGHFGETWKGYCK-----GKGTVIIKTN--IATDIT--QETFVKEAIILEKL-NHKNIISLYGVCT-ESYP--FYIVTEPING-NLKNYLTT
| | . .  |.||| .||..|     .| .| .|.    |..    .| | .|| |. .| .|.||..|||||| .. |   |||.|   . .|..|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N-----NPTPAELVDIAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQYL-NGNKYWNVKKETRLAIKWTAPEGYTAEQLSIKSDVWSF
.     ..|. .|.....|. .|| || .. .|| ||.| |.|... |.|||. |  | .. |   |  ......| |||.|||       ..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWELVTKGDLP-YRGMTDKEVKEAV-QRGYRMPIPWTSPVPFYRLIINCWNYKEDERPNFWNIFDVL
|.|.||..| |. | | ||.. ||.|.. ..|||||.|   | . |.|.  ||.|. ..|| |  |   |
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK427.AA Frk 360-607 40 4.6e-77 262.32 In-house 1-260 (260) Show / Hide 
Range on Protein: 360-607
Range on HMM: 1-260/260
Sequence Identity: 40% (105 aa)

INFSQCIHVGHFGETWKGYCKGKGTVIIKTNIATDITQETFVKEAIILEKLNHKNIISLYGVCTESYPFYIVTEPINGN-LKNYLT-----TNNPTPAEL
| . . .  | ||| | |    .  | .||  .  .  . |..|| |. || |  .|.|| |||   | ||.|| .  . |..||       ..    .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQ-YLNGNK-YWNVKKETRLAIKWTAPEGYTAEQLSIKSDVWSFGILLWELVTKGD
||.| ||  || || .| ||| || | |.|.|.|| .||| |  |   .  |.  .  . . |. |||||||    .. .|||||||||||| |..| | 
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

LPYRGMTDKEVKEAVQRGYRMPIPWTSPVPFYRLIINCWNYKEDERPNF----WNIFDVL
.|| |||..|| . |..||||| |   |. .| ....||. . ..|| |    | . | .
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK427.AA TK 360-607 18 1.2e-75 252.93 In-house 1-486 (486) Show / Hide 
Range on Protein: 360-607
Range on HMM: 1-486/486
Sequence Identity: 18% (92 aa)

INFSQCIHVGHFG---ETWKGYCKGKG--------------------------TVIIKTNIATDITQET---------------FVKEAIILEKLN----
| . . .  |.||   | .||  .|..                          .| .|.  ..| ....               | .|| ......    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIISLYGVCTES------------YPFYIVTEPIN-GN----LKNYLTTN-----------------------------------------------
 |.||..||||||..             |..||.|  . |.    |..|| ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------NPTPAELVDIAIQVTDGMMYLGEQ------DYIHCDLRAENILLGDHNT-----------VKIANFH---
                              ..|...|. .. |. .|| || ..       ..| || | |.|.|..|.           .||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FAQYL-NGNKYWNVK-----------------------KETRLAIKWTAPEGYTAEQ---------LSIKSDVWSFGILLWELVTKG-DLPYRGM
      | .. ..  |. ..                       . ..| |.|.|||  .  .          ..||||||||.|.||..| |   .| ||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------KEVKEAVQRG--------------YRMPI-PWTSP-------------VPFYRLIINCWNYKEDERPNFWNIFDVL
..         .|| | ..||              .|||  |  ..               .|.|.  ||.|. ..||.|  . . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK427.AA SrcA 360-607 42 8.2e-73 229.28 In-house 1-250 (250) Show / Hide 
Range on Protein: 360-607
Range on HMM: 1-250/250
Sequence Identity: 42% (108 aa)

INFSQCIHVGHFGETWKGYCKGKGTVIIKTNIATDITQETFVKEAIILEKLNHKNIISLYGVCTESYPFYIVTEPIN-GNLKNYLTTNNPTP---AELVD
|.  . .  | ||| | |   |.  | |||     .  |.|..|| |. || |  .. || |  |  | ||||| .. | |  .|  ..       .|||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

IAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQYLNGNKYWNVKKETRLAIKWTAPEGYTAEQLSIKSDVWSFGILLWELVTKGDLPYR
.| || .|| |.    ||| |||| ||| |..   ||| |  |  .. | | . .. ..  |||||||        |||||||||||| |||||| .|| 
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMTDKEVKEAVQRGYRMPIPWTSPVPFYRLIINCWNYKEDERPNFWNIFDVL
|| ..|| | | |||.|| |   |   . |.. ||    .||| |  .   |
GMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK427.AA TyrKc 360-607 33 1.2e-72 248.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 360-607
Range on HMM: 1-280/280
Sequence Identity: 33% (96 aa)

INFSQCIHVGHFGETWKGYCKGKGTVIIKTNIATDITQETFVKEAIILEKL--NHKNIISLYGVCTES-------YPFYIVTEPI-NGNLKNYLTTNN--
| . . .  |.||| .||  |   .| .|.  .    .| | .|| |. ||  .|.||. ||||||..        | .||.|   .|.||.||  .   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PTPAELVDIAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQYLNGN-------KYWNVKK--ETR--LAIKWTAPEGYTAEQLSIKSDV
 ....|.....|. .|| || .. .|| || | |.|.|. .||||. |  . ..          .|  .|.   ..  | |.|.|||       ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELVTKGDLPYRG-----MTDKEVKEAVQRGYRMPIPWT--------SPVPFYRLIINCWNYKEDERPNFWNIFDVL
||||...||. | |. || |     |...|| | |..|||||.|           |   |...  ||... ..||.|..| . .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK427.AA Src-Echino1 360-607 38 8.8e-70 238.15 In-house 1-252 (252) Show / Hide 
Range on Protein: 360-607
Range on HMM: 1-252/252
Sequence Identity: 38% (98 aa)

INFSQCIHVGHFGETWKGYCKGKGTVIIKTNIATDITQETFVKEAIILEKLNHKNIISLYGVCTESYPFYIVTEPI-NGNLKNYLTTNNPT---PAELVD
  . . |  ||.|| |||  .|   | .||     ...  |. || .. |. |..|. .| || .. | ||||| . ||||..||  ..      ..|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQYLNGNKYWNVKKETRLAIKWTAPEGYTAEQLSIKSDVWSFGILLWELVTKGDLPYR
.  ..  || |||.....| || | |.|.|. | .|||.|  |. .. . |   .   .| |||||||     .  |||||||||||. |.|| | .||.
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQ-GAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMTDKEVKEAVQRGYRMPIPWTSPVPFYRL-IINCWNYKEDERPNFWNIFDVL
||...|| . |.|||||| .   |   | . .. ||      || |  . | .
GMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK427.AA Abl 360-607 37 2.9e-67 223.31 In-house 1-252 (252) Show / Hide 
Range on Protein: 360-607
Range on HMM: 1-252/252
Sequence Identity: 37% (94 aa)

INFSQCIHVGHFGETWKGYCKGKG-TVIIKTNIATDITQETFVKEAIILEKLNHKNIISLYGVCTESYPFYIVTEPI-NGNLKNYLTTNNPT---PAELV
|   . .  | .|| ..|. |  . || .||     .  . |.||| |. .. |.|.. | ||||   ||||.|| . .||| .||  .. .   .  |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DIAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQYLNGNKYWNVKKETRLAIKWTAPEGYTAEQLSIKSDVWSFGILLWELVTKGDLPY
 .| |.. || || ....|| || | | |.|.|. ||.| |  |  .... |   .   .  |||||||.   .. |.||||| ||.||||. | |  ||
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

RGMTDKEVKEAVQRGYRMPIPWTSPVPFYRLIINCWNYKEDERPNFWNIFDVL
 |.  ..| . ...||||  |   |   |.|. .||.... .|| | .|   .
PGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK427.AA SrcB 360-608 39 3.3e-66 222.95 In-house 1-251 (251) Show / Hide 
Range on Protein: 360-608
Range on HMM: 1-251/251
Sequence Identity: 39% (99 aa)

INFSQCIHVGHFGETWKGYCKGKGTVIIKTNIATDITQETFVKEAIILEKLNHKNIISLYGVCTESYPFYIVTEPI-NGNLKNYLTTNNPTPAE---LVD
. . . .  | ||| | || ...  | .||     .  | |..|| .. .| |. .. || | |   | ||.|| . .| |  .| |.. .  .   |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQYLNGNKYWNVKKETRLAIKWTAPEGYTAEQLSIKSDVWSFGILLWELVTKGDLPYR
.. |...|| |. .. ||| |||| |||  .    ||| |  |  .. | |   .   .  |||||||        |||||||||||| |.|| | .|| 
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMTDKEVKEAVQRGYRMPIPWTSPVPFYRLIINCWNYKEDERPNFWNIFDVLI
|||  || ....|||||| | . |   |.... ||  . .||| |  .  || 
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK427.AA UTK 397-607 34 4.4e-65 221.59 In-house 47-296 (296) Show / Hide 
Range on Protein: 397-607
Range on HMM: 47-296/296
Sequence Identity: 34% (87 aa)

QE---TFVKEAI---ILEKLN-HKNIISLYGVCTESYPFYIVTEP-INGNLKNYLTTNNPTPA---------ELVDIAIQVTDGMMYLGEQDYIHCDLRA
.|   .| .||    .. ... | |.. |.|||| . |..||||   ||.| .|| .. |||          .... | .. .|| || .. ..|.|| |
PEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAA

ENILLGDH-------NTVKIANFH---FAQYLN---------GNKYWNVKKETRLAIKWTAPEGYTAE-QLSIKSDVWSFGILLWELVTKGDLPYRGMTD
 |.|...|       ...|||.|    .. ..|         .  | .    .|..|.|.||| .|   . ..||||||||...||..| | ||| ||..
RNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSN

KEVKEAVQRG--YRMPIPWTSPVPFYRLIINCWNYKEDERPNFWNIFDVL
 .| ..| .|  |||| ||  | | |||   ||.|  .|||.|  . ...
MQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK427.AA TK-Unique 360-607 32 6.3e-65 222.01 In-house 1-294 (294) Show / Hide 
Range on Protein: 360-607
Range on HMM: 1-294/294
Sequence Identity: 32% (95 aa)

INFSQCIHVGHFGETWKGYCKGKG-------TVIIKTNI--ATDITQETFVKEAIILEKLN-HKNIISLYGVCTESY-PFYIVTEPI-NGNLKNYLTTNN
... . |. | ||. |.|  .|.         |..|..   ||| ..  | ||. .. .|  |.||....|.||.|  |..|. |.. .||| .|| |. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

P---------------------------TPAELVDIAIQVTDGMMYLGEQDY--IHCDLRAENILLGDHNTVKIANFHFAQYLN-GNKYWNVKKETRLAI
|                           .|  |. .|.|.  ||.|| .| .  .| || | |.||......||..| .| ... ...| . ... |. |
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWTAPEGYT--AEQL-SIKSDVWSFGILLWELVTKGDLPYRGMTDKEVKEAVQRGYRMPIPWTS-PVPFYRLIINCWNYKEDERPNFWNIFDVL
.| |||      ..  ..||||||||.|.||..| |  ||.|| .|.. |....||||| |  . .  .| |...||.....|||.|  | ..|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK427.AA S_TKc 360-608 21 3.2e-30 107.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 360-608
Range on HMM: 1-231/231
Sequence Identity: 21% (58 aa)

INFSQCIHVGHFGETWKGYCKG-KGTVIIKTNIATDITQETFVKEAIILEKLNHKNIISLYGVCTESYPFYIVTEPING---NLKNYLTTNNP-------
  . . |  | ||. .|.. |. .  | ||         |.. .|  ||.| .|.||. ||.|. .   .|.|.| ..|   .|. |.  ...       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TPAELVDIAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHFAQYLNGNKYWNVKKETRLAIKWTAPEGYTAEQLSI-KSDVWSFGILLWELV
.. .   .. |. ... |. ..  ||.||  ||||| .  ..||. | .|  |         .       . |||     . .  |.|.||.|..|.|..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TKGDLPYRGMTDKEVKEAVQRGYRMPIPWTSPVPFYRLIINCWNYKEDERPNFWNIFD--------VLI
. |  |..  ..... . .            . ..  .| .|...  ..||    ..           .
C-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK427.AA Pkinase 360-493 25 8.8e-13 46.28 Pfam 1-154 (293) Show / Hide 
Range on Protein: 360-493
Range on HMM: 1-154/293
Sequence Identity: 25% (39 aa)

INFSQCIHVGHFGETWKGYCKGKGT-VIIKTNIATDITQETFVK-----EAIILEKLNHKNIISLYGVCTESYPFYIVTEPING-----NLKNYLT---T
. . ..|  | ||. .|.. || |  | .|.    ..  .  .      |. |. .|||.||. ||......   |.|.|  .|      |. |..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NNP--TPAELVDIAIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTV----KIA
..   .. |. ... |.  |. |. ..  ||.||  ||||. .....    ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKIC
Kinase AqueK427.AA Pkinase 533-600 17 1.6e-07 27.72 Pfam 192-284 (293) Show / Hide 
Range on Protein: 533-600
Range on HMM: 192-284/293
Sequence Identity: 17% (17 aa)

KSDVWSFGILLWELVTKGDLPYRGM----TDKEVKEAVQRGYRMPIPWTSP-----------------------VPFYRLIINCWNYKEDERPNF
|.|.||.|..|.|... | .|..|     .  . .. ..|  . |... .|                        ..  .| .|....  .||..
KVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA