Gene AqueK423 (A.queenslandica)

AqueK423

Species: A.queenslandica
Alias: AqueK423
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK423.AA Protein None 800 None Fasta, JSON
AqueK423.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of AqueK423.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3_2 AqueK423.AA SH3_2 246-288 15 29.60998 0.28 Pfam 1-32 (68) Show / Hide 
Range on Protein: 246-288
Range on HMM: 1-32/68
Sequence Identity: 15% (7 aa)

RIRINKKIKS-TQTLLSPNGSICEAQVDYSDPVISFKKGELLQL
..|  ..... | .  ..            .| ..||||... .
YYRVHCDYVPATYCNENH------------EPQLHFKKGDVIKV
SH3 AqueK423.AA SH3 369-427 30 2.2e-14 55.05 SMART 1-58 (58) Show / Hide 
Range on Protein: 369-427
Range on HMM: 1-58/58
Sequence Identity: 30% (18 aa)

KLFVASYNFEAQTSNNLTLKKGEVLEVVTYYEDSDWWYMHSLHTDNKGYVPINYITPIE
. ..| |...||... |..|||....|.    |..||.    .| ..|..| ||...|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK423.AA SH3_1 372-420 34 5.2e-10 36.85 Pfam 1-49 (49) Show / Hide 
Range on Protein: 372-420
Range on HMM: 1-49/49
Sequence Identity: 34% (17 aa)

VASYNFEAQTSNNLTLKKGEVLEVVTYYEDSDWWYMHSLHTDNKGYVPI
|| | ..||... |..|||....|.   .|.|||   .. |  .|..| 
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 AqueK423.AA SH3_2 370-426 17 3e-06 24.75 Pfam 1-68 (68) Show / Hide 
Range on Protein: 370-426
Range on HMM: 1-68/68
Sequence Identity: 17% (12 aa)

LFVASYNFEA-QTSNN-----LTLKKGEVLEVV---TYYEDSDWWYMHSL-HTDNK--GYVPINYITPI
....  .... .  |      |..|||.|..|    ..  | .||. .    .  .  |..|.... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWD-NWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK423.AA SH2 437-514 46 5e-28 84.1 Pfam 1-81 (81) Show / Hide 
Range on Protein: 437-514
Range on HMM: 1-81/81
Sequence Identity: 46% (38 aa)

YYH-TVSRAEAEKRLSQADTQAGTFLIRDSESNPGQHYSLSLNGGEV--TIRHYRISIENNK-YYIHPRVKFDSLNDLVHHY
.||  .||.|||..| .   . ||||.|.|||.||. |.||.  .     ..||||  ..|. |||  |.||.||..||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD-YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK423.AA SH2 435-520 41 1e-24 89.35 SMART 1-87 (87) Show / Hide 
Range on Protein: 435-520
Range on HMM: 1-87/87
Sequence Identity: 41% (37 aa)

YIYYH-TVSRAEAEKRLSQADTQAGTFLIRDSESNPGQHYSLSLNGGEVTIRHYRISIEN-NKYYIHP--RVKFDSLNDLVHHYMMKADG
. .||  .||.|||. | .   . |.||.|||||   ..|.||.  .   ..||||  .. .||||    |.||.|| .||.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWK-GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK423.AA Src 558-796 41 9.2e-82 277.56 In-house 10-255 (255) Show / Hide 
Range on Protein: 558-796
Range on HMM: 10-255/255
Sequence Identity: 41% (103 aa)

GRFGETWVGFCKGKGPVMIKTNIATDITQETFLDKAIILVKLHHKNIISLYGVCTESYPFYIVTEPINRN-LKGYLTK----NNPTPAELVDIAIQVTDG
| ||| | |  .|. .| .||  . .  .| ||  | |. || |.....|| ||..  |.|||||  ... |  || |     .    .|.|.| || .|
GQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLIDMAAQVAEG

MMYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHLN--GNKYWTVEKGTDLAIRWTAPEGYTLKRLSIKSDVWSFGILLWELGTKRKEPYPGMTNGT
|.|| .. ||| ||.| |.| | .| .||| | ||. .    . | . ..|  . |.|||||  .  | .||||||||||||.|. |. . |||||||  
MAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY-CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHE

VKEAVSKGYHMPIPRDCPKPFKQ-LMINCWKYKDDERPSFKNVFDVL
| ..|..||.|| |. ||. . . .|  ||. . ..|| |.  ...|
VLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK423.AA SFK-Src 558-791 41 9.2e-80 235.93 In-house 10-250 (259) Show / Hide 
Range on Protein: 558-791
Range on HMM: 10-250/259
Sequence Identity: 41% (99 aa)

GRFGETWVGFCKGKGPVMIKTNIATDITQETFLDKAIILVKLHHKNIISLYGVCTESYPFYIVTEPI-NRNLKGYLTK---NNPTPAELVDIAIQVTDGM
| ||. | |   ..  | .||     . .| ||  | .. || | | | || |||   | ||.|| . .  |  ||        .   ||| | ||  ||
GQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVDMAAQVAHGM

MYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHLNGNKY-WTVEKGTDLAIRWTAPEGYTLKRLSIKSDVWSFGILLWELGTKRKEPYPGMTNGTVK
 || .| ..| || | |.| |  |..||. | ..  |  .   .| ..|    |.|||||  .  | ||||||||||||. |. |    |||||||  | 
AYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEVL

EAVSK--GYHMPIPRDCPKPFKQLMINCWKYKDDERPSFKN
  | .  || || |  ||  . ..|..||. . |.|| | .
QQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFES
Kinase AqueK423.AA SrcA 552-796 44 1.5e-73 231.7 In-house 4-250 (250) Show / Hide 
Range on Protein: 552-796
Range on HMM: 4-250/250
Sequence Identity: 44% (112 aa)

FSDISVGRFGETWVGFCKGKGPVMIKTNIATDITQETFLDKAIILVKLHHKNIISLYGVCTESYPFYIVTEPINRN-----LKGYLTKNNPTPAELVDIA
   .  | ||| |.|   |.  | |||     .  |.||. | |. ||.|  .. || |  |  | ||||| ...      ||.   |.   | .|||.|
ERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLP-QLVDMA

IQVTDGMMYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHLNGNKYWTVEKGTDLAIRWTAPEGYTLKRLSIKSDVWSFGILLWELGTKRKEPYPGM
 || .|| |.    ||| |||| ||| |     |.| | ||  .. | | | ..|.   |.|||||     |  |||||||||||| || || . |||||
AQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM

TNGTVKEAVSKGYHMPIPRDCPKPFKQLMINCWKYKDDERPSFKNVFDVL
 |  | | | .||||| |.|||.   .||. ||.   .||| |  .   |
NNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK423.AA Frk 550-800 40 3.9e-71 242.62 In-house 1-260 (260) Show / Hide 
Range on Protein: 550-800
Range on HMM: 1-260/260
Sequence Identity: 40% (104 aa)

IKF-SDISVGRFGETWVGFCKGKGPVMIKTNIATDITQETFLDKAIILVKLHHKNIISLYGVCTESYPFYIVTEPINRN-LKGYLT-----KNNPTPAEL
|..   .  |.||| | |    . || .||  .  .  . ||  | |. || |  .|.|| |||   | ||.|| . .. |. ||       ..    .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQVTDGMMYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHLNGNKY--WTVEKGTDLAIRWTAPEGYTLKRLSIKSDVWSFGILLWELGTKRK
||.| ||  || || .| ||| || | |.|.|  | .|.| | ||  |  ..   .    |  . |.|||||    .. .|||||||||||| |. |  .
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

EPYPGMTNGTVKEAVSKGYHMPIPRDCPKPFKQLMINCWKYKDDERPSFKNVFDVLIKYS
 |||||||  | . |..|| || | .||. . ..|..||. . ..|| |  .   | .| 
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK423.AA TK 558-796 19 2.5e-70 234.72 In-house 10-486 (486) Show / Hide 
Range on Protein: 558-796
Range on HMM: 10-486/486
Sequence Identity: 19% (94 aa)

GRFG---ETWVGFCKGKG--------------------------PVMIKTNIATDITQET-FLD----------------KAIILVK---LHHKNIISLY
| ||   | . |  .|..                          || .|.  ..| .... |.|                 .. . .   .||.||..||
GQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLY

GVCTES------------YPFYIVTEPIN-RN----LKGYLTKN--------------------------------------------------------
||||..             |..||.|  .  .    |. || |.                                                        
GVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHP

---------------------NPTPAELVDIAIQVTDGMMYLAEQ------DYIHCDLRAENILLGYTNT-----------VKVANFH--------LAQH
                     ..|...|. .. |. .|| ||...       ..| || | |.|.|  |.           .|.| |         ||  
PPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARD

L-NGNKYWTVE-----------------------KGTDLAIRWTAPEGYT---------LKRLSIKSDVWSFGILLWELGTKRKEPYPG-MTN-------
. ..  |....                       .|. | |||.|||  .          .. ..||||||||.|.||. |  .|||.| |.|       
IYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDG

--GTVKEAVSKG--------------YHMPIPRDCP--------------KPFKQLMINCWKYKDDERPSFKNVFDVL
    | | . .|              . || | .||              . . .||  ||.|. ..||.|. . . |
DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK423.AA Pkinase_Tyr 558-796 38 7.6e-69 233.78 Pfam 10-270 (270) Show / Hide 
Range on Protein: 558-796
Range on HMM: 10-270/270
Sequence Identity: 38% (100 aa)

GRFGETWVGFCK-----GKGPVMIKTN--IATDIT--QETFLDKAIILVKL-HHKNIISLYGVCT-ESYP--FYIVTEPINR-NLKGYLTKN-----NPT
| ||| . | .|     .| || .|.    |..    .| |.  | |. .| ||.||..|||||| .. |   |||.|     .|. || |.     ..|
GAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLT

PAELVDIAIQVTDGMMYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHL-NGNKYWTVEKGTDLAIRWTAPEGYTLKRLSIKSDVWSFGILLWELGT
. .|.....|. .|| ||... .|| ||.| |.|.. .|.||.. | ||  . |   | .. .|..| |.|.|||    .. ..||||||||.|.||. |
MKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFT

KRKEP-YPGMTNGTVKEAV-SKGYHMPIPRDCPKPFKQLMINCWKYKDDERPSFKNVFDVL
  ..| ||||.|  |.|..  .|| ||.|..||..  .||  ||.|. ..||.|. .   |
YGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK423.AA Src-Echino1 553-796 37 3.2e-65 223.01 In-house 5-252 (252) Show / Hide 
Range on Protein: 553-796
Range on HMM: 5-252/252
Sequence Identity: 37% (94 aa)

SDISVGRFGETWVGFCKGKGPVMIKTNIATDITQETFLDKAIILVKLHHKNIISLYGVCTESYPFYIVTEPI-NRNLKGYLTKNNPT---PAELVDIAIQ
  |  |..|| | |  .|  || .||     ...  ||  | .. |. |..|. .| || .. | ||||| . | ||. || ...      ..|.|.  .
KKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLIDMGAH

VTDGMMYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHLNGNKYWTVEKGTDLAIRWTAPEGYTLKRLSIKSDVWSFGILLWELGTKRKEPYPGMTN
.  || || .....| || | |.|.|  | .|.|.| ||. .. . | . . |  | |.|||||     |  |||||||||||. |. |  . |||||.|
IASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQ-GAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPGMMN

GTVKEAVSKGYHMPIPRDCPKPFKQL-MINCWKYKDDERPSFKNVFDVL
  | . | .|| || . .||    .. |. ||      || |. . | .
REVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK423.AA Abl 550-796 37 6.9e-65 215.23 In-house 2-252 (252) Show / Hide 
Range on Protein: 550-796
Range on HMM: 2-252/252
Sequence Identity: 37% (94 aa)

IKFSDISVGRFGETWVGFCKGKGP-VMIKTNIATDITQETFLDKAIILVKLHHKNIISLYGVCTESYPFYIVTEPI-NRNLKGYLTKNNPT---PAELVD
.    .  | .|| ..|  |  .  | .||     .  . ||  | |. ...|.|.. | ||||   ||||.|| . . ||  || ... .   .  |. 
MMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLLY

IAIQVTDGMMYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHLNGNKYWTVEKGTDLAIRWTAPEGYTLKRLSIKSDVWSFGILLWELGTKRKEPYP
.| |.. || || ....|| || | | |.|  . |||| | ||  .... | | . |    |.|||||.   .. |.||||| ||.||||. |    |||
MATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYP

GMTNGTVKEAVSKGYHMPIPRDCPKPFKQLMINCWKYKDDERPSFKNVFDVL
|.    | . . ||| |  |. ||.   .|| .||...  .|||||..   .
GIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK423.AA SrcB 550-797 38 1.2e-63 214.16 In-house 1-251 (251) Show / Hide 
Range on Protein: 550-797
Range on HMM: 1-251/251
Sequence Identity: 38% (98 aa)

IKFSD-ISVGRFGETWVGFCKGKGPVMIKTNIATDITQETFLDKAIILVKLHHKNIISLYGVCTESYPFYIVTEPINR-NLKGYLTKNNPTPAE---LVD
.|.   .  | ||| |.|. ...  | .||     .  | ||. | .. .| |. .. || | |   | ||.|| ...  |  .|  .. .  .   |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAIQVTDGMMYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHLNGNKYWTVEKGTDLAIRWTAPEGYTLKRLSIKSDVWSFGILLWELGTKRKEPYP
.. |...|| |. .. ||| |||| |||   |   |.| | ||  .. | | |   |    |.|||||        |||||||||||| |. |  . |||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMTNGTVKEAVSKGYHMPIPRDCPKPFKQLMINCWKYKDDERPSFKNVFDVLI
||||  | .....|| || |  ||.   ..|. ||| . .||| |  .  || 
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK423.AA TyrKc 550-796 34 7.7e-61 209.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 550-796
Range on HMM: 1-280/280
Sequence Identity: 34% (97 aa)

IKFSD-ISVGRFGETWVGFCKGKGPVMIKTNIATDITQETFLDKAIILVKL--HHKNIISLYGVCTES-------YPFYIVTEPI-NRNLKGYLTKNN--
|.. . .  | ||| . |  |   .| .|.  .    .| |.. | |. ||  ||.||. ||||||..        | .||.|   . .|| || |.   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PTPAELVDIAIQVTDGMMYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHLNGN-------KYWTV--EKGTD--LAIRWTAPEGYTLKRLSIKSDV
 ....|.....|. .|| ||... .|| || | |.|.|  .|||.. | |.  .          .| ..  .||..  | |||.|||    .. ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELGTKRKEPYPG-----MTNGTVKEAVSKGYHMPIPRD--------CPKPFKQLMINCWKYKDDERPSFKNVFDVL
||||...||. |  ..||||     |.|  | | | .|| ||.| .        ||.   |.|  ||... ..||.|... . .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK423.AA UTK 586-796 33 1.6e-59 202.26 In-house 47-296 (296) Show / Hide 
Range on Protein: 586-796
Range on HMM: 47-296/296
Sequence Identity: 33% (84 aa)

QE---TFLDKAI---ILVKLH-HKNIISLYGVCTESYPFYIVTEP-INRNLKGYLTKNNPTPA---------ELVDIAIQVTDGMMYLAEQDYIHCDLRA
.|   .|.  |    .. ..| | |.. |.|||| . |..||||   | .|  || .. |||          .... | .. .|| ||... ..|.|| |
PEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAA

ENILLGYT-------NTVKVANFH---LAQHLN---------GNKYWTVEKGTDLAIRWTAPEGYTLK-RLSIKSDVWSFGILLWELGTKRKEPYPGMTN
 |.|..         ...|.|.|    ..  .|         .  | .    . ..|||.||| .|   | ..||||||||...||. |  . |||||.|
RNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSN

GTVKEAVSKG--YHMPIPRDCPKPFKQLMINCWKYKDDERPSFKNVFDVL
  | ..|..|  |.|| |.||| |  .||  ||.|  .|||.|. . ...
MQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK423.AA Src-Unclassified 558-796 37 5e-59 201.02 In-house 10-284 (284) Show / Hide 
Range on Protein: 558-796
Range on HMM: 10-284/284
Sequence Identity: 37% (102 aa)

GRFGETWVGFCKGKGPVMIKTNIAT---DITQETFL--------DKAIILVKLHHKNIISLYGVCTESYPFYIVTE-PINRNLKGYLTKNN---PTPAEL
| ||| | |  .||  | .||  .        | ||          | |. |. | |.. ||.||..  |.||.||  ||  | ..| .     .   ..
GQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGGGQYLHIQDM

------------VDIAIQVTDGMMYLAEQDYIHCDLRAENILLGYTN-----TVKVANFHLA-QHLNGNKYWTVEKGTDLAIRWTAPEGYTLKRLSIKSD
            |||| ||  ||||| .  |.| || | |.| |  |      |||. | ||   | .       .|  . . |.|||  .    |||||
SEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIYGNFSIKSD

VWSFGILLWELGTKRKEPYPGMTNGTVKEAVSKGYHMPIP--RDCPKPFKQ-LMINCWKYKDDERPSFKNVFDVL
|||.||||||..|| . ||||| | .| | |. || || |  . ||    . .|  ||    . || |   .  .
VWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
S_TKc AqueK423.AA S_TKc 549-797 21 1.1e-21 79.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 549-797
Range on HMM: 1-231/231
Sequence Identity: 21% (58 aa)

HIKFSDISVGRFGETWVGFCKG-KGPVMIKTNIATDITQETFLDKAIILVKLHHKNIISLYGVCTESYPFYIVTEPINR---NLKGYLTKNNP-------
  .   |  | ||. . .  |. .  | ||         |...    || | ||.||. ||.|. .   .|.|.| ..    .|. |. |...       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TPAELVDIAIQVTDGMMYLAEQDYIHCDLRAENILLGYTNTVKVANFHLAQHLNGNKYWTVEKGTDLAIRWTAPEGYTLKRLSI-KSDVWSFGILLWELG
.. .   .. |. ... |. ..  ||.||  |||||    ..|.. | || .|         .       . |||       .  |.|.||.|..|.|. 
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TKRKEPYPGMTNGTVKEAVSKGYHMPIPRDCPKPFKQLMINCWKYKDDERPSFKNVFD--------VLI
. .. |.|   . . |  .            ....|... .|...  ..||.   ..           .
C-GYPPFP-QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK423.AA Pkinase 595-796 21 1.4e-17 63.26 Pfam 53-293 (293) Show / Hide 
Range on Protein: 595-796
Range on HMM: 53-293/293
Sequence Identity: 21% (53 aa)

ILVKLHHKNIISLYGVCTESYPFYIVTEPINR-----NLKGYLT---KNNP--TPAELVDIAIQVTDGMMYLAEQDYIHCDLRAENILLGYTNTV----K
|. .|.|.||. ||......   |.|.|  .       |. |..   ...   .. |. ... |.  |. |. ..  ||.||  ||||.  ....    |
IMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVK

VANFHLAQH--LNGNKYWTVEKGTDLAIRWTAPEGYT-LKRLSIKSDVWSFGILLWELGTKRKEPYPGM----TNGTVKEAVSKGYHMPIPRDCP-----
.. | || .  .  |   |.  ||   ... |||     .  . |.|.||.|..|.|. ..|  |.||     .  . .. . .  . |...|.|     
ICDFGLAKQFDY-NNS-MTTFCGT---PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR-PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSI

------------------KPFKQLMINCWKYKDDERPSFKNVFDV--L
                  ...|... .|....  .||... ..    .
SYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF