Gene AqueK422 (A.queenslandica)

AqueK422

Species: A.queenslandica
Alias: AqueK422
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK422.AA Protein None 1272 None Fasta, JSON
AqueK422.kin_dom Protein Kinase Domain None 247 None Fasta, JSON

Protein domain

Protein domains of AqueK422.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Death AqueK422.AA Death 20-108 20 0.003469 12.96 Pfam 1-87 (87) Show / Hide 
Range on Protein: 20-108
Range on HMM: 1-87/87
Sequence Identity: 20% (18 aa)

NEIIEILEQYNFPEAKWFKFGLKLGLLYPTLEAIDA-NHRGNTSRCLMECLSKWLSKADENVYPPTWKTLASALKKLEGKAVAENIEKTM
 .....|.  . | ..| ... |||. .  .. |   .......   .. | ||  .   .    | ..|..||.|..   .||.|.  .
QKLCRLLDPDHHPGKDWRRLARKLGMSDNEIDQIEHDQNPHDLRSQTYQMLWKWEQR---HGKNATVDHLIEALRKMGRRDCAEKIQSWL
Death AqueK422.AA Death 237-259 34 0.114756 7.86 Pfam 65-87 (87) Show / Hide 
Range on Protein: 237-259
Range on HMM: 65-87/87
Sequence Identity: 34% (8 aa)

QTLASALRKLEAISVAENIEKTM
..|..||||.. . .||.|.  .
DHLIEALRKMGRRDCAEKIQSWL
SH3 AqueK422.AA SH3 834-892 35 8.3e-13 49.8 SMART 1-58 (58) Show / Hide 
Range on Protein: 834-892
Range on HMM: 1-58/58
Sequence Identity: 35% (21 aa)

KLFKASYNFEASNLQDLSLKKGEVLEVVEYENDDHWWYMHSLATDNRGEVPINYIIPIE
. ..| |...|.| ..||.|||....|.| . ||.||.     | ..| .| ||. .|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK422.AA SH3_1 837-885 32 2.6e-10 37.83 Pfam 1-49 (49) Show / Hide 
Range on Protein: 837-885
Range on HMM: 1-49/49
Sequence Identity: 32% (16 aa)

KASYNFEASNLQDLSLKKGEVLEVVEYENDDHWWYMHSLATDNRGEVPI
.| | ..|.. ..||.|||....|.| ..|..||   .. |  .| .| 
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 AqueK422.AA SH3_2 835-891 17 1e-06 26.13 Pfam 1-68 (68) Show / Hide 
Range on Protein: 835-891
Range on HMM: 1-68/68
Sequence Identity: 17% (12 aa)

LFKASYNFEA-SNLQD-----LSLKKGEVLEVV---EYENDDHWWYMHSL-ATDNR--GEVPINYIIPI
....  .... .. ..     |..|||.|..|    ....| .||. .   ..  |  | .|.... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWD-NWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK422.AA SH2 908-980 44 4e-25 75.6 Pfam 6-81 (81) Show / Hide 
Range on Protein: 908-980
Range on HMM: 6-81/81
Sequence Identity: 44% (34 aa)

VSRTESVKLLSKPDTEAGTFLIRDSERKPGQHYTLSLNDGF---TIKHYHINNEFNK-YYTSRNLKFDSLNHLVQHC
.|| |  .|| .|  . ||||.|.||..||. ||||. |.     .|||.|... |. || . . ||.||..||.| 
ISRQEAERLLMNPGNPDGTFLVRESESTPGD-YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK422.AA SH2 902-986 37 1.2e-20 75.78 SMART 1-87 (87) Show / Hide 
Range on Protein: 902-986
Range on HMM: 1-87/87
Sequence Identity: 37% (33 aa)

YVYYH-MVSRTESVKLLSKPDTEAGTFLIRDSERKPGQHYTLSLNDGFTIKHYHINNEF-NKYYTSR--NLKFDSLNHLVQHCMMKAHG
. .|| ..|| | ..|| .|  . |.||.||||.   ..|.||. ..  .|||.|. .  .|||     . ||.|| .||.| .  . |
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK422.AA Src 1018-1264 42 3e-93 316.1 In-house 1-255 (255) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-255/255
Sequence Identity: 42% (108 aa)

IKFLKCINAGQFGETWKGNWKGNGPVRIKTNIATNITQETFIEEANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIINGNLRDY-H------YVAPTEL
||... . .||||| |.| |.|| .| .||  . .  .| | .||.|.|||  |.... || ||... |.|||||   .|.| || .      ..  ..|
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLR-HEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQL

VDIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLN-GKKYYNIKKYSVLTYRWTAPEGYTLNQLSIKSDVWSFGILLWELATKGKE
.|.| || .|| |||.. ||| ||.| |.| | || .|.| |  |. .  ..  |. .. . . ..|||||  . .. .||||||||||||.|. |.|. 
IDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYPGMTDEEVKEAVLEGYQMPIPQGCPEPFDQ-LMINCWKQDDDERPNFRNIFDLL
|||||| .|| ..|  || || |..||. . . .|  ||..| ..|| |  ... |
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK422.AA SFK-Src 1018-1259 42 6.3e-93 275.69 In-house 1-250 (259) Show / Hide 
Range on Protein: 1018-1259
Range on HMM: 1-250/259
Sequence Identity: 42% (106 aa)

IKFLKCINAGQFGETWKGNWKGNGPVRIKTNIATNITQETFIEEANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIINGNLRDYHYV------APTELV
|.  |   .||||. ||| | .   | .||     . .| | .|| ..|||  |.| | || |||   | ||.|| . .| | ||             ||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLR-HPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLV

DIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLNGKKY-YNIKKYSVLTYRWTAPEGYTLNQLSIKSDVWSFGILLWELATKGKEP
| | ||  || |||.| ..| || | |.| | ||..|.. |  .  |  .   |  ..      .|||||  . |. ||||||||||||. |. | |  |
DMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIP

YPGMTDEEVKEAVLE--GYQMPIPQGCPEPFDQLMINCWKQDDDERPNFRN
|||||  ||   |    || || |..||. . ..|..||..  |.|| | .
YPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFES
Kinase AqueK422.AA Frk 1018-1268 42 4.3e-80 272.38 In-house 1-260 (260) Show / Hide 
Range on Protein: 1018-1268
Range on HMM: 1-260/260
Sequence Identity: 42% (110 aa)

IKFLKCINAGQFGETWKGNWKGNGPVRIKTNIATNITQETFIEEANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIINGNLRDYHY--------VAPTE
|.... . .||||| | | |  . || .||  .  .  . |. || |.|||  |  .| || ||| . | ||.|| . .| | .|          .  ..
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLR-HPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQ

LVDIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLNGKKY--YNIKKYSVLTYRWTAPEGYTLNQLSIKSDVWSFGILLWELATKG
|||.| ||  || |||.| ||| || | |.|.| .| .||| |  |  |   .   |  .    .  .|||||    |. .|||||||||||| |. | |
LVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYG

KEPYPGMTDEEVKEAVLEGYQMPIPQGCPEPFDQLMINCWKQDDDERPNFRNIFDLLIKYD
. ||||||. || . | .|| || | .||. . ..|..||..| ..|| |  .   | .| 
RMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK422.AA SrcA 1018-1264 45 7.1e-80 252.0 In-house 1-250 (250) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-250/250
Sequence Identity: 45% (115 aa)

IKFLKCINAGQFGETWKGNWKGNGPVRIKTNIATNITQETFIEEANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIINGNLRDY------HYVAPTELV
|.  . .  |.||| | | | |.  | |||     .  |.|.||| |.|||  |. .. || |  |. | ||||| .  | | |.      .|.   .||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLR-HDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLV

DIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLNGKKYYNIKKYSVLTYRWTAPEGYTLNQLSIKSDVWSFGILLWELATKGKEPY
|.| || .|| |.|   ||| |||| ||| | |   ||| |  |  ..    |. .. .    .|||||        |||||||||||| || |||. ||
DMAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNE-YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY

PGMTDEEVKEAVLEGYQMPIPQGCPEPFDQLMINCWKQDDDERPNFRNIFDLL
||| . || | | .||.|| ||.|||   .||. ||..| .||| |  .   |
PGMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK422.AA TK 1018-1264 20 3.7e-75 251.22 In-house 1-486 (486) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-486/486
Sequence Identity: 20% (102 aa)

IKFLKCINAGQFG---ETWKGNWKGNG--------------------------PVRIKTNIAT-NITQETFIE--------------EANILKKLT----
|...| . .||||   | .|| |.| .                          || .|.  .. . .|| |..              ||...|..     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

WHQNIIILYGVCTED------------YPFYIVTEPIINGN----LRDYHY-------------------------------------------------
 |.||. ||||||..             |..||.|   .|.    ||||                                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VAPTELVDIAIQVVNGMIYLEEQ------DYIHCDLRAENILLGYNNT-----------VKIANFHYA-
                               . . .|. .. |. .|| ||...       ..| || | |.|.| ||.           .||| |  . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------QHLN------------------------GKKYYNIKKYSVLTYRWTAPEGYT---------LNQLSIKSDVWSFGILLWELATKGKEPYPG-M
         ..                        . .||  ..   |  ||.|||  .          .  ..||||||||.|.||. | |.|||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------EEVKEAVLEG--------------YQMPIPQGCP--------------EPFDQLMINCWKQDDDERPNFRNIFDLL
..         .|| | . .|              ..|| |..||              | ...||  ||. | ..||.|. . . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK422.AA Src-Unclassified 1018-1264 37 3.1e-73 249.63 In-house 1-284 (284) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-284/284
Sequence Identity: 37% (108 aa)

IKFLKCINAGQFGETWKGNWKGNGPVRIKTNIAT---NITQETFI--------EEANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIINGNLRDY----
.. |. .  ||||| |.| |.|   | .||  .        | |         .||.|.||.  |||.. ||.||... |.||.||  ||| | ..    
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCR-HQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREG

--HYVAPTEL------------VDIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNN-----TVKIANFHYA-QHLNGKKYYNIKKYSVLTYRWTAPEGY
   |    ..            |||| || .|| |||.  |.| || | |.| | ||      ||.. |  |   | .   |  .. . .   |.|||  
GGQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECF

TLNQLSIKSDVWSFGILLWELATKGKEPYPGMTDEEVKEAVLEGYQMPIP--QGCPEPFDQ-LMINCWKQDDDERPNFRNIFDLL
.    ||||||||.||||||..|||. |||||  .|| | |  || || |  ..||.   . .|  || .| . || |   .  .
IYGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK422.AA Src-Echino1 1018-1264 40 3.3e-72 246.19 In-house 1-252 (252) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-252/252
Sequence Identity: 40% (104 aa)

IKFLKCINAGQFGETWKGNWKGNGPVRIKTNIATNITQETFIEEANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIINGNLRDY------HYVAPTELV
 .. | |  |..|| ||| |.|| || .||     ...  |. |||..||.  |..|. .| || .  | ||||| . ||||.||      . |  |.|.
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCR-HEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLI

DIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLNGKKYYNIKKYSVLTYRWTAPEGYTLNQLSIKSDVWSFGILLWELATKGKEPY
|.  ..  || ||......| || | |.|.|  | .|||.|  |. .. |  |  |.   |  .|||||     .  |||||||||||. |. | |. ||
DMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQ-KDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPY

PGMTDEEVKEAVLEGYQMPIPQGCPEPFDQL-MINCWKQDDDERPNFRNIFDLL
|||.. || . | .||.|| .. ||.   .. |. || .|   || |. . | .
PGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK422.AA Pkinase_Tyr 1018-1264 39 8.8e-72 243.73 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-270/270
Sequence Identity: 39% (107 aa)

IKFLKCINAGQFGETWKGNWK-----GNGPVRIKTN--IATNIT--QETFIEEANILKKLTWHQNIIILYGVCT-EDYP--FYIVTEPIINGNLRDYHYV
|.|.| . .|.||| .|| ||     .. || .|.    |.     .| |..||.|.|.|  |.||. |||||| .. |   |||.|   .|.|.||   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

A--------PTELVDIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLNGKKYY-NIKKYSVLTYRWTAPEGYTLNQLSIKSDVWSF
         . .|.....|. .|| |||.. .|| ||.| |.|.. ||.|||. |  |  .  . ||   .. . |  .|.|||    .  ..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWELATKGKEP-YPGMTDEEVKEAV-LEGYQMPIPQGCPEPFDQLMINCWKQDDDERPNFRNIFDLL
|.|.||. | |..| ||||..|||.|..  .||.||.|..||..  .||  ||..| ..|| |. |   |
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK422.AA UTK 1018-1264 31 1.6e-71 243.88 In-house 1-296 (296) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-296/296
Sequence Identity: 31% (92 aa)

IKFLKCINAGQFGETWKGNWK------GNGPVRIKTNI---ATNITQE---TFIEEAN---ILKKLTWHQNIIILYGVCTEDYPFYIVTEPIINGNLRDY
....... .|.|||  |. ..      .   |..|..    ... ..|   .|.|||.   ..|.. ||.|.. |.|||| . |..||||   ||.||.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

------------HYVAPTELVDIAIQVVNGMIYLEEQDYIHCDLRAENILLGYN-------NTVKIANFH---YAQHLN---------GKKYYNIKKYSV
            |..  ..... | .. .|| ||... ..|.|| | |.|.. .       ...|||.|    ..  .|         .  ||.      
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LTYRWTAPEGYTLN-QLSIKSDVWSFGILLWELATKGKEPYPGMTDEEVKEAVLEG--YQMPIPQGCPEPFDQLMINCWKQDDDERPNFRNIFDLL
.. ||.||| .| . . ..||||||||...||. | |. |||||....| ..|..|  |.|| |..||.|  .||  ||..| .|||.|. . . .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK422.AA Abl 1018-1264 38 1e-70 234.97 In-house 1-252 (252) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-252/252
Sequence Identity: 38% (97 aa)

IKFLKCINAGQFGETWKGNWKG-NGPVRIKTNIATNITQETFIEEANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIINGNLRDY------HYVAPTEL
|   . .  ||.|| ..| ||  .  | .||    ..  . |..|| |.|..  |.|.. | |||| . ||||.|| . .||| ||      . . .  |
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMK-HPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVL

VDIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLNGKKYYNIKKYSVLTYRWTAPEGYTLNQLSIKSDVWSFGILLWELATKGKEP
. .| |.  || |||....|| || | | |.| .. ||.| |  |  ...   |  .       .|||||.   |. |.||||| ||.||||.|| |  |
LYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKD-DTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSP

YPGMTDEEVKEAVLEGYQMPIPQGCPEPFDQLMINCWKQDDDERPNFRNIFDLL
|||.  ..| . . .|| |  |.|||.   .|| .||. .  .|| |..|   .
YPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK422.AA TyrKc 1018-1264 35 2.9e-67 230.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-280/280
Sequence Identity: 35% (101 aa)

IKFLKCINAGQFGETWKGNWKGNGPVRIKTNIATNITQETFIEEANILKKL-TWHQNIIILYGVCTED-------YPFYIVTEPIINGNLRDY-----HY
|...| .  |.||| .|| ||   .| .|.  .    .| |..||.|..||   |.||. ||||||..        | .||.|   .|.|.||     . 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

VAPTELVDIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLNGK-------KYYNI----KKYSVLTYRWTAPEGYTLNQLSIKSDV
. . .|.....|. .|| ||... .|| || | |.|.| |.||||. |  .  .  .       .||       . ..| .||.|||    .  ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELATKGKEPYPG-----MTDEEVKEAVLEGYQMPIPQG--------CPEPFDQLMINCWKQDDDERPNFRNIFDLL
||||...||. | |..||||     |...|| | | .|| ||.|.         ||.   |.|  ||. | ..||.|..| ...
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK422.AA SrcB 1018-1265 39 9.1e-67 224.86 In-house 1-251 (251) Show / Hide 
Range on Protein: 1018-1265
Range on HMM: 1-251/251
Sequence Identity: 39% (101 aa)

IKFLKCINAGQFGETWKGNWKGNGPVRIKTNIATNITQETFIEEANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIINGNLRDY------HYVAPTELV
.|. | . |||||| | | ....  | .||     .  | |..|||..|.|  |. .. || | | . | ||.|| . .| | |.        ..   |.
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQ-HDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLI

DIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLNGKKYYNIKKYSVLTYRWTAPEGYTLNQLSIKSDVWSFGILLWELATKGKEPY
|.. |.  || |.|.. ||| |||| |||       ||| |  |  ..    |  .       .|||||        |||||||||||| |. | |. ||
DMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNE-YTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPY

PGMTDEEVKEAVLEGYQMPIPQGCPEPFDQLMINCWKQDDDERPNFRNIFDLLI
||||  || ... .|| || |. |||   ..|. |||.  .||| |  .   | 
PGMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK422.AA S_TKc 1018-1266 23 2.8e-27 97.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 1018-1266
Range on HMM: 1-231/231
Sequence Identity: 23% (63 aa)

IKFLKCINAGQFGETWKGNWKG-NGPVRIKTNIATNITQETFIEEANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIIN--GNLRDYHY----------
 ..|. |  | ||. .|. .|. .  | ||         |... | .||||   | ||. ||.|. .   .|.|.| . .  |.|.||            
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

VAPTELVDIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTVKIANFHYAQHLNGKKYYNIKKYSVLTYRWTAPEGYTLNQLSI-KSDVWSFGILLWEL
  . .   .. |..... |. ..  ||.||  |||||    ..||. |  | .|         .  . |  . |||     . .  |.|.||.|..|.|.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

ATKGKEPYPGMTDEEVKEAVLEGYQMPIPQGCPEPFDQLMINCWKQDDDERPNFRNIFD-------LLIK
.. |. |.|  ..... . ..           .... ... .|.. | ..||    ..            
LC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK422.AA Pkinase 1018-1264 21 1.5e-21 77.31 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1018-1264
Range on HMM: 1-293/293
Sequence Identity: 21% (66 aa)

IKFLKCINAGQFGETWKGNWKGNG-PVRIKTNIATNITQETFIE-----EANILKKLTWHQNIIILYGVCTEDYPFYIVTEPIING----NLR------D
......| .| ||. .|. .||.|  | .|.    ..  .  ..     |. |.|.|  | ||. ||......   |.|.|   .|     |       .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

YHYV--APTELVDIAIQVVNGMIYLEEQDYIHCDLRAENILLGYNNTV----KIANFHYAQHLNGKKYYNIKKYSVL--TYRWTAPEGYT-LNQLSIKSD
.  .   . |. ... |.. |. |. ..  ||.||  ||||.  |...    ||. |  | ...   | |   ....  |... |||     .  . |.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VWSFGILLWELATKGKEPYPGM----TDEEVKEAVLEGYQMPIPQGCP-----------------------EPFDQLMINCWKQDDDERPNFRNIFDL--
.||.|..|.|... |. |.||     .  . .. . .  . |..  .|                       |.. ... .|...|  .||... |.    
MWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

L
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F