Gene AqueK421 (A.queenslandica)

AqueK421

Species: A.queenslandica
Alias: AqueK421
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK421.AA Protein None 305 None Fasta, JSON
AqueK421.kin_dom Protein Kinase Domain None 247 None Fasta, JSON

Protein domain

Protein domains of AqueK421.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK421.AA SFK-Src 53-293 42 1.1e-93 277.93 In-house 1-248 (259) Show / Hide 
Range on Protein: 53-293
Range on HMM: 1-248/259
Sequence Identity: 42% (106 aa)

IKFFQCINAGQFGETWKGDCKDKGPVIIKTNIATNIVQETFLEEANILKKLNHKNIISLYGACTESYPFYIVTEPI-NGSLKDYLTT---NNPTPAELVA
|.  .   .||||. |||   ..  | .||     . .| ||.|| ..||| | | | ||  ||   | ||.|| . .||| |||        .   || 
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

ITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHLNGNKY-WIAKKKDKLAKKWTAPEGYTLNRLSIKSDVWSFGILLWELVSKGKEPY
 . ||  || || .| ..| || | |.| || |..|.. | ..| |  .   . |..  |   ||||||  . || ||||||||||||. |.|  |  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMTDEEVKEAVSK--GYHMPIPRDCPEPFKLLMMNCWKQNEYERPNF
||||  ||   | .  || || |  ||. .  .|..||...  .|| |
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF
Kinase AqueK421.AA Src 53-300 42 1.1e-92 314.28 In-house 1-255 (255) Show / Hide 
Range on Protein: 53-300
Range on HMM: 1-255/255
Sequence Identity: 42% (108 aa)

IKFFQCINAGQFGETWKGDCKDKGPVIIKTNIATNIVQETFLEEANILKKLNHKNIISLYGACTESYPFYIVTE-PINGSLKDYLT----TNNPTPAELV
||. . . .||||| |.|  ... .| .||  . .  .| ||.||.|.||| |.....||  |..  |.|||||   .||| |||     . .    .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

AITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHLN--GNKYWIAKKKDKLAKKWTAPEGYTLNRLSIKSDVWSFGILLWELVSKGKE
 .. || .||.||... ||| ||.| |.| |..| .|.| | ||| .    . |  |..  |.  ||||||  . .| .||||||||||||.|.|..|. 
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY-CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYPGMTDEEVKEAVSKGYHMPIPRDCPEPFKL-LMMNCWKQNEYERPNFIHIFNIL
|||||| .|| ..|..||.|| |. ||. .   .|. ||..   .|| |  ... |
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK421.AA Pkinase_Tyr 53-300 39 2.6e-84 286.17 Pfam 1-270 (270) Show / Hide 
Range on Protein: 53-300
Range on HMM: 1-270/270
Sequence Identity: 39% (106 aa)

IKFFQCINAGQFGETWKGDCK-----DKGPVIIKTN--IATNIV--QETFLEEANILKKL-NHKNIISLYGACT-ESYP--FYIVTEPING-SLKDYLTT
|.| . . .|.||| .|| .|     .| || .|.    |.     .| |..||.|.|.| .|.||..|||.|| .. |   |||.|   . .|.||| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N-----NPTPAELVAITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHL-NGNKYWIAKKKDKLAKKWTAPEGYTLNRLSIKSDVWSF
.     ..|. .|. . .|. .|| || .. .|| ||.| |.|... |.|||. | ||| . |   |  .... ||  ||.|||    .. ..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWELVSKGKEP-YPGMTDEEVKEAV-SKGYHMPIPRDCPEPFKLLMMNCWKQNEYERPNFIHIFNIL
|.|.||... |..| ||||..|||.|..  .|| ||.|..||..   ||. ||...  .|| |  | ..|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK421.AA TK 53-300 20 1.5e-81 273.0 In-house 1-486 (486) Show / Hide 
Range on Protein: 53-300
Range on HMM: 1-486/486
Sequence Identity: 20% (98 aa)

IKFFQCINAGQFG---ETWKGDCKDKG--------------------------PVIIKTNIATNIVQET---------------FLEEANILKKLN----
|.. . . .||||   | .||  ....                          || .|.  ...  ...               |||||...|...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIISLYGACTES------------YPFYIVTEPIN-GS----LKDYLTTN-----------------------------------------------
 |.||..|||.||..             |..||.|  . |.    |.||| ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------NPTPAELVAITIQVTDGMMYLGEQ------DYIHCDLRAENILLGDHNT-----------VKIANFH---
                              ..|...|. .  |. .|| || ..       ..| || | |.|.|..|.           .||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARHLN------------------------GNKYWIAKKKDKLAKKWTAPEGYT---------LNRLSIKSDVWSFGILLWELVSKGKEPYPG-M
     ||| ..                        . .|  .....||  .|.|||  .          .. ..||||||||.|.||... |.|||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------EEVKEAVSKG--------------YHMPIPRDCP--------------EPFKLLMMNCWKQNEYERPNFIHIFNIL
..         .|| | . .|              . || | .||              | . .||. ||. .  .||.|  . . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK421.AA SrcA 53-300 46 5.7e-79 249.09 In-house 1-250 (250) Show / Hide 
Range on Protein: 53-300
Range on HMM: 1-250/250
Sequence Identity: 46% (117 aa)

IKFFQCINAGQFGETWKGDCKDKGPVIIKTNIATNIVQETFLEEANILKKLNHKNIISLYGACTESYPFYIVTEPIN-GSLKDYLTTNNPTP---AELVA
|.  . .  |.||| | |    .  | |||     .  |.||||| |.||| |  .. ||    |  | ||||| .. ||| |.|  ..       .|| 
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

ITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHLNGNKYWIAKKKDKLAKKWTAPEGYTLNRLSIKSDVWSFGILLWELVSKGKEPYP
.. || .|| |.    ||| |||| ||| |..   ||| | ||| .. | |  |..  |   ||||||     |  |||||||||||| ||| ||. |||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMTDEEVKEAVSKGYHMPIPRDCPEPFKLLMMNCWKQNEYERPNFIHIFNIL
|| . || | | .||||| |.||||    ||. ||...  ||| |  .   |
GMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK421.AA Frk 53-293 42 1.2e-78 267.58 In-house 1-249 (260) Show / Hide 
Range on Protein: 53-293
Range on HMM: 1-249/260
Sequence Identity: 42% (107 aa)

IKFFQCINAGQFGETWKGDCKDKGPVIIKTNIATNIVQETFLEEANILKKLNHKNIISLYGACTESYPFYIVTEPI-NGSLKDYLT-----TNNPTPAEL
|.. . . .||||| | |    . || .||  .  .  . || || |.||| |  .|.||  ||   | ||.|| . .|||..||       ..    .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VAITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHLNGNKY--WIAKKKDKLAKKWTAPEGYTLNRLSIKSDVWSFGILLWELVSKGK
| .. ||  || || .| ||| || | |.|.|.|| .||| | ||| |  ..   . ..   ..  ||||||    |. .|||||||||||| |..  |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

EPYPGMTDEEVKEAVSKGYHMPIPRDCPEPFKLLMMNCWKQNEYERPNF
 ||||||. || . |..|| || | .||. .  .|..||...  .|| |
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTF
Kinase AqueK421.AA TyrKc 53-300 34 1.1e-74 255.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 53-300
Range on HMM: 1-280/280
Sequence Identity: 34% (98 aa)

IKFFQCINAGQFGETWKGDCKDKGPVIIKTNIATNIVQETFLEEANILKKL--NHKNIISLYGACTES-------YPFYIVTEPI-NGSLKDYLTTNN--
|.. . .  |.||| .||  |   .| .|.  .    .| |..||.|..||  .|.||. |||.||..        | .||.|   .|.|||||  .   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PTPAELVAITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHLNGN-------KYWIAKK--KDK--LAKKWTAPEGYTLNRLSIKSDV
 ....|. . .|. .|| || .. .|| || | |.|.|. .||||. | |.| .          .|  .|.    |  |  .|.|||    .. ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELVSKGKEPYPG-----MTDEEVKEAVSKGYHMPIPRD--------CPEPFKLLMMNCWKQNEYERPNFIHIFNIL
||||...||. . |..||||     |...|| | | .|| ||.| .        ||.    .|  ||. .  .||.|  |  ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK421.AA SrcB 53-301 42 3.1e-73 247.09 In-house 1-251 (251) Show / Hide 
Range on Protein: 53-301
Range on HMM: 1-251/251
Sequence Identity: 42% (107 aa)

IKFFQCINAGQFGETWKGDCKDKGPVIIKTNIATNIVQETFLEEANILKKLNHKNIISLYGACTESYPFYIVTEPI-NGSLKDYLTTNNPTPAE---LVA
.|. . . |||||| | |  ...  | .||     .  | ||.|||..|.| |. .. ||   |   | ||.|| . .|.| |.| |.. .  .   |. 
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

ITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHLNGNKYWIAKKKDKLAKKWTAPEGYTLNRLSIKSDVWSFGILLWELVSKGKEPYP
.. |...|| |. .. ||| |||| |||  .    ||| | ||| .. | |  |.   |   ||||||        |||||||||||| |.|  |. |||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMTDEEVKEAVSKGYHMPIPRDCPEPFKLLMMNCWKQNEYERPNFIHIFNILY
|||  || .....|| || |  |||    .|| |||.   ||| | ..  .| 
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK421.AA Src-Echino1 53-300 39 2.2e-71 243.49 In-house 1-252 (252) Show / Hide 
Range on Protein: 53-300
Range on HMM: 1-252/252
Sequence Identity: 39% (101 aa)

IKFFQCINAGQFGETWKGDCKDKGPVIIKTNIATNIVQETFLEEANILKKLNHKNIISLYGACTESYPFYIVTEPI-NGSLKDYLTTNNPT---PAELVA
 .. . |  |..|| |||  .   || .||     . .  || |||..||. |..|. .|  | .. | ||||| . ||.|.|||  ..      ..|. 
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

ITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHLNGNKYWIAKKKDKLAKKWTAPEGYTLNRLSIKSDVWSFGILLWELVSKGKEPYP
.  ..  || |||.....| || | |.|.|. | .|||.| ||| .. . | ..|.  ||  ||||||     |  |||||||||||. |.|  |. |||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVY-CGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMTDEEVKEAVSKGYHMPIPRDCPEPFKLL-MMNCWKQNEYERPNFIHIFNIL
||.. || . | .|| || . .||.    . || || ..   || | .. . .
GMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK421.AA Src-Unclassified 53-300 36 5.5e-70 238.83 In-house 1-284 (284) Show / Hide 
Range on Protein: 53-300
Range on HMM: 1-284/284
Sequence Identity: 36% (103 aa)

IKFFQCINAGQFGETWKGDCKDKGPVIIKTNIAT---NIVQETFL--------EEANILKKLNHKNIISLYGACTESYPFYIVTE-PINGSLKDYLTTNN
..    .  ||||| |.|  . |  | .||  .        | ||        .||.|.||. | |.. ||. |..  |.||.||  ||||| ..| .  
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

---PTPAEL------------VAITIQVTDGMMYLGEQDYIHCDLRAENILLGDHN-----TVKIANFHLAR-HLNGNKYWIAKKKDKLAKKWTAPEGYT
   .   ..            | |  ||  ||||| .  |.| || | |.| |. |      ||.. | |||  | .    ....  ..  ||.|||  .
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

LNRLSIKSDVWSFGILLWELVSKGKEPYPGMTDEEVKEAVSKGYHMPIP--RDCPEPFKL-LMMNCWKQNEYERPNFIHIFNIL
    ||||||||.||||||.  ||. |||||  .|| | |. || || |  . ||.     .|  || .    || |   .. .
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK421.AA Abl 53-300 38 1.1e-69 231.54 In-house 1-252 (252) Show / Hide 
Range on Protein: 53-300
Range on HMM: 1-252/252
Sequence Identity: 38% (97 aa)

IKFFQCINAGQFGETWKGDCKDKGPVI-IKTNIATNIVQETFLEEANILKKLNHKNIISLYGACTESYPFYIVTEPI-NGSLKDYLTTNNPT---PAELV
|   . .  ||.|| ..|  |  . .. .||    ..  . ||.|| |.|.. |.|.. | | ||   ||||.|| . .| | |||  .. .   .  |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

AITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHLNGNKYWIAKKKDKLAKKWTAPEGYTLNRLSIKSDVWSFGILLWELVSKGKEPY
 .  |.. || || ....|| || | | |.|.|. ||.| | ||| .... |  |.   |   ||||||.   |. |.||||| ||.||||.   |  ||
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

PGMTDEEVKEAVSKGYHMPIPRDCPEPFKLLMMNCWKQNEYERPNFIHIFNIL
||.  ..| . . ||| |  |. ||.    || .||. .. .|| | .| . .
PGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK421.AA UTK 53-293 32 3e-68 232.58 In-house 1-289 (296) Show / Hide 
Range on Protein: 53-293
Range on HMM: 1-289/296
Sequence Identity: 32% (93 aa)

IKFFQCINAGQFGETWKGDCKD------KGPVIIKTNI---ATNIVQE---TFLEEAN---ILKKLN-HKNIISLYGACTESYPFYIVTEP-INGSLKDY
... ... .|.|||  |.. ..      .  | .|..    ...  .|   .|.|||.   ..|... | |.. |.| || . |..||||   ||.| .|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LTTNNPTPA---------ELVAITIQVTDGMMYLGEQDYIHCDLRAENILLGDH-------NTVKIANFH---LARHLN---------GNKYWIAKKKDK
| .. |||          ...    .. .|| || .. ..|.|| | |.|...|       ...|||.|    ..| .|         .  |  |   |.
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LAKKWTAPEGYTLN-RLSIKSDVWSFGILLWELVSKGKEPYPGMTDEEVKEAVSKG--YHMPIPRDCPEPFKLLMMNCWKQNEYERPNF
.. .|.||| .| . | ..||||||||...||... |. |||||....| ..|..|  |.|| |.|||.|   ||. ||...  |||.|
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDF
Kinase AqueK421.AA S_TKc 53-302 23 4.2e-34 120.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 53-302
Range on HMM: 1-231/231
Sequence Identity: 23% (62 aa)

IKFFQCINAGQFGETWKGDCKD-KGPVIIKTNIATNIVQETFLEEANILKKLNHKNIISLYGACTESYPFYIVTEPING---SLKDYLTTNNP-------
 .. . |  | ||. .|.  |. .  | ||         |... | .|||| .|.||. ||... .   .|.|.| ..|   .|.||.  ...       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TPAELVAITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTVKIANFHLARHLNGNKYWIAKKKDKLAKKWTAPEGYTLNRLSI-KSDVWSFGILLWELV
.. .   .. |. ... |. ..  ||.||  ||||| .  ..||. | |||.|         .       . |||       .  |.|.||.|..|.|..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SKGKEPYPGMTDEEVKEAVSKGYHMPIPRDCPEPFKLLMMNCWKQNEYERPNFIHIFN-------ILYL
. |. |.|  ..... . .            ....| ....|.. .  .||    ...         ..
C-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK421.AA Pkinase 53-186 25 1.2e-13 49.33 Pfam 1-154 (293) Show / Hide 
Range on Protein: 53-186
Range on HMM: 1-154/293
Sequence Identity: 25% (40 aa)

IKFFQCINAGQFGETWKGDCKDKG-PVIIKTNIATNIVQETFLE-----EANILKKLNHKNIISLYGACTESYPFYIVTEPING-----SLKDYLT---T
... ..| .| ||. .|.  |. |  | .|.    ..  .   .     |. |.|.|||.||. ||......   |.|.|  .|     .|.||..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NNP--TPAELVAITIQVTDGMMYLGEQDYIHCDLRAENILLGDHNTV----KIA
..   .. |.  .  |.  |. |. ..  ||.||  ||||. .....    ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKIC
Kinase AqueK421.AA Pkinase 226-302 19 2.4e-11 41.17 Pfam 192-293 (293) Show / Hide 
Range on Protein: 226-302
Range on HMM: 192-293/293
Sequence Identity: 19% (20 aa)

KSDVWSFGILLWELVSKGKEPYPGM----TDEEVKEAVSKGYHMPIPRDCP-----------------------EPFKLLMMNCWKQNEYERPNFIHIFN
|.|.||.|..|.|... |. |.||     .  . .. . .  . |...|.|                       |..| .. .|.... ..||.. .|..
KVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

ILYL
  ..
HPWF