Gene AqueK420 (A.queenslandica)

AqueK420

Species: A.queenslandica
Alias: AqueK420
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK420.AA Protein None 1010 None Fasta, JSON
AqueK420.kin_dom Protein Kinase Domain None 238 None Fasta, JSON

Protein domain

Protein domains of AqueK420.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Death AqueK420.AA Death 33-109 21 0.000207 17.07 Pfam 13-87 (87) Show / Hide 
Range on Protein: 33-109
Range on HMM: 13-87/87
Sequence Identity: 21% (17 aa)

PEAKWFEFGLNLGLLYPTLEAIKV-NHRGNTSRCLMECLSKWLSKADENVYPPTWQTLASALRKLEAKAVAENIEKTM
| ..| ...  ||. .  .. |.  .......   .. | ||  .   .    | ..|..||||..   .||.|.  .
PGKDWRRLARKLGMSDNEIDQIEHDQNPHDLRSQTYQMLWKWEQR---HGKNATVDHLIEALRKMGRRDCAEKIQSWL
SH3 AqueK420.AA SH3 572-631 33 9.6e-09 36.3 SMART 1-58 (58) Show / Hide 
Range on Protein: 572-631
Range on HMM: 1-58/58
Sequence Identity: 33% (20 aa)

KVFVASCDVQAIKPEDLTIKKGEILEVVNNDEINDDWWYMHSLHTDNNGCVPVKYMIPIK
....| .| ||  |..|..|||.|..|.. |  .|.||.    .| . | .|  |  .|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKD--DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 AqueK420.AA SH3_2 573-630 20 5e-06 24.03 Pfam 1-68 (68) Show / Hide 
Range on Protein: 573-630
Range on HMM: 1-68/68
Sequence Identity: 20% (14 aa)

VFVASCDVQA-IKPED-----LTIKKGEILEVV-NNDEINDDWWYMHSL-HTDNN--GCVPVKYMIPI
.... ||...  ....     |..|||....|  | |. .|.||. .    .     | .| ... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH3_1 AqueK420.AA SH3_1 581-624 34 6e-06 23.32 Pfam 7-49 (49) Show / Hide 
Range on Protein: 581-624
Range on HMM: 7-49/49
Sequence Identity: 34% (15 aa)

QAIKPEDLTIKKGEILEVVNNDEINDDWWYMHSLHTDNNGCVPV
||  |..|..|||.|..|.. ..  .|||   .. |   | .|.
QAQQPDELSFKKGDIIHVIEKSDD-WDWWKGRCNNTGQEGWFPS
SH2 AqueK420.AA SH2 642-718 43 6.8e-29 86.65 Pfam 2-81 (81) Show / Hide 
Range on Protein: 642-718
Range on HMM: 2-81/81
Sequence Identity: 43% (35 aa)

YFHTVSRDEAVKLMLQANIQAGAFLIRESESNPGQHYSLSVNDGL---TIQHYRINSENNK-HYINPDDQFDSLNDLVHHY
|.  .|| || .| ..   . |.||.|||||.||. |.||| |.     ..||||....|. .||  ...|.||..||.||
YHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD-YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK420.AA SH2 640-724 35 9.9e-23 82.75 SMART 1-87 (87) Show / Hide 
Range on Protein: 640-724
Range on HMM: 1-87/87
Sequence Identity: 35% (32 aa)

SIYFH-TVSRDEAVKLMLQANIQAGAFLIRESESNPGQHYSLSVNDGLTIQHYRINSEN-NKHYINP--DDQFDSLNDLVHHYMMKADG
  ..|  .||.||..| ..   . |.||.|.|||   ..|.||| ..  ..||||.... .| ||    . .|.|| .||.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK420.AA Src 754-1002 41 1.8e-89 303.56 In-house 1-255 (255) Show / Hide 
Range on Protein: 754-1002
Range on HMM: 1-255/255
Sequence Identity: 41% (106 aa)

IKFIKCSYVGWFGETWEGKWKGKGPVIIKTNIATNIAQEKFFQQANILKNLQHKNIISLYGVCTESYPFYIVTEQINKN-LRYYLL----ENDVILAKLV
||...    | ||| |.|.|.|. .| .||  . . ..| | | |.|.|.|.|.....|| ||..  |.|||||  ... |  ||     .  . | .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHLN--GNKYRTVEESTMLPYKWTAPEGYTINQISIKSDVWSFGILLWEMVTKGD
|.| || ||| ||... ||| ||.| |.|. | || .|.| | ||. .    . | . ..  ..|.||||||  . .. .||||||||||||.|.||.| 
DMAAQVAEGMAYLESMNYIHRDLAARNVLV-GENNVCKVADFGLARLIKEDDDEY-CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGR

LPYYGMTNEEVRELVSKGDHLFIPRNCPEPFQQ-LMINCWRHKDYERPNFKNIFDVL
 || ||||.|| . |..| ..  |.|||. . . .|  ||. .  .|| |. ....|
VPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK420.AA SFK-Src 754-997 41 3.5e-85 252.32 In-house 1-250 (259) Show / Hide 
Range on Protein: 754-997
Range on HMM: 1-250/259
Sequence Identity: 41% (104 aa)

IKFIKCSYVGWFGETWEGKWKGKGPVIIKTNIATNIAQEKFFQQANILKNLQHKNIISLYGVCTESYPFYIVTEQI-NKNLRYYLLE---NDVILAKLVD
|.  |    | ||. | |.| ..  | .||     . .| | | | ..| |.| | | || |||   | ||.|| . .  |  || |       . .|||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

IAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHLNGNKY-RTVEESTMLPYKWTAPEGYTINQISIKSDVWSFGILLWEMVTKGDLP
 | ||  || || .| ..| || | |.|. | ||..|.. | ..  |  .    | .|    | ||||||  ..|. ||||||||||||. |.|| |  |
MAAQVAHGMAYLEAQNFVHRDLAARNVLV-GDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIP

YYGMTNEEVRELVSK--GDHLFIPRNCPEPFQQLMINCWRHKDYERPNFKN
| |||| ||   | .  |  .  | |||. . ..|..||.|.  .|| | .
YPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFES
Kinase AqueK420.AA Frk 754-1006 41 1.1e-76 261.07 In-house 1-260 (260) Show / Hide 
Range on Protein: 754-1006
Range on HMM: 1-260/260
Sequence Identity: 41% (108 aa)

IKFIKCSYVGWFGETWEGKWKGKGPVIIKTNIATNIAQEKFFQQANILKNLQHKNIISLYGVCTESYPFYIVTEQINKN-LRYYLL-----ENDVILAKL
|..|.    | ||| |||.|  . || .||  .  .  . | . | |.|.|.|  .|.|| |||   | ||.|| . .. |  ||       . . . .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQ-HLNGNK--YRTVEESTMLPYKWTAPEGYTINQISIKSDVWSFGILLWEMVTK
||.| ||  || || .| ||| || | |.|. | .| .||| | ||   .  |.  | .  .   .| ||||||    |. .|||||||||||| |..| 
VDMAAQVAAGMAYLESQNYIHRDLAARNVLV-GEHNICKIADFGLARVLMKDNEDIYESRHG-ARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITY

GDLPYYGMTNEEVRELVSKGDHLFIPRNCPEPFQQLMINCWRHKDYERPNFKNIFDVLITYD
| .|| |||| || . |..|  .  | |||. . ..|..||...  .|| |  .   |  | 
GRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK420.AA Pkinase_Tyr 765-1002 38 2.4e-75 255.82 Pfam 12-270 (270) Show / Hide 
Range on Protein: 765-1002
Range on HMM: 12-270/270
Sequence Identity: 38% (100 aa)

FGETWEGKWK-----GKGPVIIKTN--IATNIA--QEKFFQQANILKNL-QHKNIISLYGVCT-ESYP--FYIVTEQINK-NLRYYLLEN-----DVILA
||| ..|.||     .| || .|.    |.  .  .|.|.. |.|.|.| .|.||..|||||| .. |   |||.|   . .|. || ..      . . 
FGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMK

KLVDIAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHL-NGNKYRTVEESTMLPYKWTAPEGYTINQISIKSDVWSFGILLWEMVTK
 |.....|. .|| || .. .|| ||.| |.|..  ||.|||. | ||  . |   | .. ....|| ||.|||    .  ..||||||||.|.||..| 
DLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTY

GDLP-YYGMTNEEVRELV-SKGDHLFIPRNCPEPFQQLMINCWRHKDYERPNFKNIFDVL
|. | |.||.|||| |..  .|  . .|.|||..  .||  ||...  .|| |. |   |
GEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK420.AA SrcA 754-1002 45 5.6e-73 229.82 In-house 1-250 (250) Show / Hide 
Range on Protein: 754-1002
Range on HMM: 1-250/250
Sequence Identity: 45% (114 aa)

IKFIKCSYVGWFGETWEGKWKGKGPVIIKTNIATNIAQEKFFQQANILKNLQHKNIISLYGVCTESYPFYIVTEQINK-NLRYYLLEND---VILAKLVD
|. ..    | ||| | | | |.  | |||     .. | | . | |.| |.|  .. || |  |  | ||||| ..|  |  .| ...   . | .|||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

IAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHLNGNKYRTVEESTMLPYKWTAPEGYTINQISIKSDVWSFGILLWEMVTKGDLPY
.| || ||| |.    ||| |||| |||. | |   ||| | ||  .. | | | .  .  | ||||||        |||||||||||| |.|||| .||
MAAQVAEGMAYMERMNYIHRDLRAANILV-GENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY

YGMTNEEVRELVSKGDHLFIPRNCPEPFQQLMINCWRHKDYERPNFKNIFDVL
 || | || | | .| |.  |..|||   .||. |||    ||| |  .   |
PGMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK420.AA SRM 763-1003 43 1.8e-69 231.48 In-house 10-253 (253) Show / Hide 
Range on Protein: 763-1003
Range on HMM: 10-253/253
Sequence Identity: 43% (107 aa)

GWFGETWEGKWKGKGPVIIKTNIATN-IAQEKFFQQANILKNLQHKNIISLYGVCTESYPFYIVTEQINK-NLRYYLLEND---VILAKLVDIAIQVTEG
|.||| ||| |||. .| ||     | . |... .    .| | || ||.|. ||.   | ||.||   | ||  || . |     . .|.|.| || ||
GYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLDFACQVAEG

MIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHLNGNKYRTVEESTMLPYKWTAPEGYTINQISIKSDVWSFGILLWEMVTKGDLPYYGMTNEEV
| || || ||| || | |.|. | ||. |.. | ||  .    |    ..   ||||||||       |.|||||||||||.|| |.| .|| |||| | 
MCYLEEQNYIHRDLAARNVLV-GDNNLCKVGDFGLARLIKDDIYSPSHDHNI-PYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPGMTNHET

RELVSKGDHLFIPRNCPEPFQQLMINCWRHKDYERPNFKNIFDVLI
   ...|  .  |  ||     ||. ||.    .|| ||     | 
FQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase AqueK420.AA SrcB 754-1003 41 6.6e-69 232.2 In-house 1-251 (251) Show / Hide 
Range on Protein: 754-1003
Range on HMM: 1-251/251
Sequence Identity: 41% (106 aa)

IKFIKCSYVGWFGETWEGKWKGKGPVIIKTNIATNIAQEKFFQQANILKNLQHKNIISLYGVCTESYPFYIVTEQINKNLRYYLLEND----VILAKLVD
.|..|    | ||| | | ....  | .||     .. | | . ||..|.|||. .. || | |   | ||.|| ..|      |  |    . | ||.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHLNGNKYRTVEESTMLPYKWTAPEGYTINQISIKSDVWSFGILLWEMVTKGDLPY
.. |..||| |. .. ||| |||| |||.       ||| | ||  .. | | |  |    | ||||||        |||||||||||| |.|| | .||
MSAQIAEGMAYIERMNYIHRDLRAANILVS-ETLCCKIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPY

YGMTNEEVRELVSKGDHLFIPRNCPEPFQQLMINCWRHKDYERPNFKNIFDVLI
 |||| || . ...|  .  | ||||   ..|. ||...  ||| |  .  || 
PGMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK420.AA TK 754-1002 18 4.4e-68 227.09 In-house 1-486 (486) Show / Hide 
Range on Protein: 754-1002
Range on HMM: 1-486/486
Sequence Identity: 18% (92 aa)

IKFIKCSYVGWFG---ETWEGKWKGKG--------------------------PVIIKTNIATNIAQEKFFQQ---------------ANILKNLQ----
|...|    |.||   | ..|.|.|..                          || .|.  ... .... |..               |...| ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIISLYGVCTES------------YPFYIVTEQIN-KN----LRYYLLEND----------------------------------------------
 |.||..||||||..             |..||.|  .  .    || || ...                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VILAKLVDIAIQVTEGMIYLGEQ------DYIHCDLRAINILIEGYNN----------TVKIANFH---
                               . .. |. .. |. .|| || ..       ..| || | |.|.   |.          ..||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAQHLNGNKYRTVEE------------------------STMLPYKWTAPEGYT---------INQISIKSDVWSFGILLWEMVTKGDLPYYG-M
     ||  .. ... .. .                        ...|| .|.|||  .          .  ..||||||||.|.||..| |. |||| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------EEVRELVSKGDHL-----------FIPR---NCP--------------EPFQQLMINCWRHKDYERPNFKNIFDVL
.|         .|| |.. .|  |           . .    .||              | ...||  ||...  .||.|. . . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK420.AA Src-Echino1 754-1002 37 9e-67 228.15 In-house 1-252 (252) Show / Hide 
Range on Protein: 754-1002
Range on HMM: 1-252/252
Sequence Identity: 37% (96 aa)

IKFIKCSYVGWFGETWEGKWKGKGPVIIKTNIATNIAQEKFFQQANILKNLQHKNIISLYGVCTESYPFYIVTEQI-NKNLRYYLLENDVI---LAKLVD
 .. |    | .|| |.| |.|  || .||     ... .|   ||..| ..|..|. .| || .. | ||||| . | ||. || ...     ...|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHLNGNKYRTVEESTMLPYKWTAPEGYTINQISIKSDVWSFGILLWEMVTKGDLPY
.  ..  || |||.....| || | |.|. |  | .|||.| ||. .. . | . .    || ||||||     .  |||||||||||. |||| | .||
MGAHIASGMDYLGSKNVVHRDLAARNVLV-GKGNVCKIADFGLARMMQKDVYCGKQ-GAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPY

YGMTNEEVRELVSKGDHLFIPRNCPEPFQQL-MINCWRHKDYERPNFKNIFDVL
 ||.| || . | .|  .  . .||.   .. |. ||      || |. . | .
PGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK420.AA Abl 754-1002 37 3e-63 209.67 In-house 1-252 (252) Show / Hide 
Range on Protein: 754-1002
Range on HMM: 1-252/252
Sequence Identity: 37% (96 aa)

IKFIKCSYVGWFGETWEGKWKGKGPVI-IKTNIATNIAQEKFFQQANILKNLQHKNIISLYGVCTESYPFYIVTEQINK-NLRYYLLEND---VILAKLV
|   .    | .|| .|| ||  . .. .||    ... . | . | |.|...|.|.. | ||||   ||||.|| . . ||  || |.|   .    |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DIAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHLNGNKYRTVEESTMLPYKWTAPEGYTINQISIKSDVWSFGILLWEMVTKGDLP
 .| |.. || || ....|| || | | |. | .. ||.| | ||  .... | | .     | ||||||.   |. |.||||| ||.||||. | |  |
YMATQIASGMSYLEKRHFIHRDLAARNCLV-GEHHIVKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSP

YYGMTNEEVRELVSKGDHLFIPRNCPEPFQQLMINCWRHKDYERPNFKNIFDVL
| |.  ..| ... ||  .  |. ||.   .|| .||. .  .|| ||.|   .
YPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK420.AA TyrKc 754-1002 32 1.4e-62 215.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 754-1002
Range on HMM: 1-280/280
Sequence Identity: 32% (93 aa)

IKFIKCSYVGWFGETWEGKWKGKGPVIIKTNIATNIAQEKFFQQANILKNL--QHKNIISLYGVCTES-------YPFYIVTEQINK-NLRYYLLEND--
|...|    | ||| ..|.||   .| .|.  .    .| | . |.|...|  .|.||. ||||||..        | .||.|   . .|. || ..   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

VILAKLVDIAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHLNGN-------KYRTVEE--STM--LPYKWTAPEGYTINQISIKSD
. ...|.....|. .|| || .. .|| || | |.|.   . ||||. | |.  .          .| .. |  ..   ||..|.|||    .  ..|||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGILLWEMVTKGDLPYYG-----MTNEEVRELVSKGDHLFIPRN--------CPEPFQQLMINCWRHKDYERPNFKNIFDVL
|||||...||. | |. ||.|     |.|.||.|.| .|. . .| |        ||.   |.|  ||...  .||.|..| . .
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK420.AA Src-Unclassified 763-1002 37 2.8e-58 198.41 In-house 10-284 (284) Show / Hide 
Range on Protein: 763-1002
Range on HMM: 10-284/284
Sequence Identity: 37% (105 aa)

GWFGETWEGKWKGKGPVIIKTNIAT---NIAQEKFF--------QQANILKNLQHKNIISLYGVCTESYPFYIVTEQ-INKNLRYYLLEND---VILAKL
| ||| | |||.||  | .||  .      . | |         | |.|.| ..| |.. ||.||..  |.||.||  ||  |  .| | .     .  .
GQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGGGQYLHIQDM

------------VDIAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNN-----TVKIANFHLA--QHLNGNKYRTVEESTMLPYKWTAPEGYTINQISIK
            |||| ||  || || .  |.| || | |.|| | ||      ||.. | ||         |     . |.| ||.|||  .    |||
SEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLI-GHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGA-MFPWKWMAPECFIYGNFSIK

SDVWSFGILLWEMVTKGDLPYYGMTNEEVRELVSKGDHLFIP--RNCPEPFQQ-LMINCWRHKDYERPNFKNIFDVL
|||||.||||||. |||  || || |.|| | |. |  .  |  . ||.   . .|  ||      || |   .  .
SDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK420.AA S_TKc 756-1003 19 3.5e-18 67.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 756-1003
Range on HMM: 1-231/231
Sequence Identity: 19% (53 aa)

FIKCSYVGW--FGETWEGKWKG-KGPVIIKTNIATNIAQEKFFQQANILKNLQHKNIISLYGVCTESYPFYIVTEQINK---NLRYYLLEND-------V
. .   .|   ||. . ...|. .  | ||         |.. .  .|||. .|.||. ||.|. .   .|.|.| ..    .|. |. ..         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

ILAKLVDIAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTVKIANFHLAQHLNGNKYRTVEESTMLPYKWTAPEGYTINQISI-KSDVWSFGILLWEM
       .. |. ... |. ..  ||.||   |||.     ..||. | || .|          .      . |||     . .  |.|.||.|..|.||
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VTKGDLPYYGMTNEEVRELVSKGDHLFIPRNCPEPFQQLMINCWRHKDYERPNFKNIFD--------VLI
.. |  |..  . ... ...            .... ... .|..    .||    ..           .
LC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK420.AA Pkinase 798-1002 21 4.4e-17 61.5 Pfam 51-293 (293) Show / Hide 
Range on Protein: 798-1002
Range on HMM: 51-293/293
Sequence Identity: 21% (53 aa)

ANILKNLQHKNIISLYGVCTESYPFYIVTEQINK-----NLRYYLL--ENDVI---LAKLVDIAIQVTEGMIYLGEQDYIHCDLRAINILIEGYNNTV--
. |.|.|.|.||. ||......   |.|.|  ..      |  |.   .. ..      . ... |. .|. |. ..  ||.||   ||||   |...  
IQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA

--KIANFHLAQH--LNGNKYRTVEESTMLPYKWTAPEGYT-INQISIKSDVWSFGILLWEMVTKGDLPYYGM----TNEEVRELVSKGDHLFIPRNCP--
  ||. | || .  .  |   |.   |   . . |||     . .. |.|.||.|..|.||.. | .|..|     .  . .... .  .  .....|  
CVKICDFGLAKQFDY-NNS-MTTFCGT---PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWW

---------------------EPFQQLMINCWRHKDYERPNFKNIFDV--L
                     |...... .|.. . ..||... |.    .
CSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF