Gene AqueK415 (A.queenslandica)

AqueK415

Species: A.queenslandica
Alias: AqueK415
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK415.AA Protein None 337 None Fasta, JSON
AqueK415.kin_dom Protein Kinase Domain None 132 None Fasta, JSON

Protein domain

Protein domains of AqueK415.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 AqueK415.AA SH2 47-131 32 6e-15 56.9 SMART 1-87 (87) Show / Hide 
Range on Protein: 47-131
Range on HMM: 1-87/87
Sequence Identity: 32% (29 aa)

HVYYH-MVSHDDAEKKLRLADRQSGTFLISESESRPEQNLILSLSDGIIIRYYRIYIEF-NKYYTFP--RVKFDSLNDLIHHYMMKADG
. .|| ..| ..||..|.    . |.||. .|||   . ..||. ..  .. |||  .  .|||     |.||.|| .|..||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 AqueK415.AA SH2 57-125 39 5.9e-13 39.86 Pfam 10-81 (81) Show / Hide 
Range on Protein: 57-125
Range on HMM: 10-81/81
Sequence Identity: 39% (29 aa)

DAEKKLRLADRQSGTFLISESESRPEQNLILSLSDGI---IIRYYRIYIEFNK-YYTFPRVKFDSLNDLIHHY
.||. |.    . ||||. |||| | .   ||. |.     .. |||  . |. || . |.||.||..|..||
EAERLLMNPGNPDGTFLVRESESTPGD-YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase AqueK415.AA Src 198-329 39 5.6e-48 161.08 In-house 125-255 (255) Show / Hide 
Range on Protein: 198-329
Range on HMM: 125-255/255
Sequence Identity: 39% (53 aa)

AENILLGIGDRHITVKIANFNFARNLN-GSKYWTVKEDTTLAIKWIAPEAFALKRLSIKSDVWSFGILVWELTTKGKEPYPGMTKEKVTEAVSKGYHMPI
| |.| | .     .|.| |  || .  .    . ...  . ||| ||||.   | .||||||||||| .|. |.|. ||||||.. | ..|..||.|| 
ARNVLVGENN---VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPC

PQDCPEPFKQ-LMMNCWQNEDDHRPSFKDIFNLL
|. ||. . . .|. ||... . || |. ... |
PHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK415.AA SrcA 198-329 48 4.1e-46 143.44 In-house 123-250 (250) Show / Hide 
Range on Protein: 198-329
Range on HMM: 123-250/250
Sequence Identity: 48% (64 aa)

AENILLGIGDRHITVKIANFNFARNLNGSKYWTVKEDTTLAIKWIAPEAFALKRLSIKSDVWSFGILVWELTTKGKEPYPGMTKEKVTEAVSKGYHMPIP
| ||| |    ..  ||| |  || ..   | | .  .   ||| ||||    |  |||||||||||  ||.|||. ||||| .  | | | .||||| |
AANILVG---ENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYHMPCP

QDCPEPFKQLMMNCWQNEDDHRPSFKDIFNLL
|||||   .||. ||. . . || |  .   |
QDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK415.AA SFK-Src 211-322 46 2.4e-45 131.97 In-house 134-248 (259) Show / Hide 
Range on Protein: 211-322
Range on HMM: 134-248/259
Sequence Identity: 46% (53 aa)

TVKIANFNFARNLNGSKY-WTVKEDTTLAIKWIAPEAFALKRLSIKSDVWSFGILVWELTTKGKEPYPGMTKEKVTEAVSK--GYHMPIPQDCPEPFKQL
..|.. |  .| |      .| .|     ||| ||||    | ||||||||||||  |. | |  ||||||   |   | .  || || |. ||. . ..
VCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKI

MMNCWQNEDDHRPSF
|..||| | | || |
MFDCWQHEPDDRPTF
Kinase AqueK415.AA Pkinase_Tyr 200-329 40 3.3e-45 153.73 Pfam 141-270 (270) Show / Hide 
Range on Protein: 200-329
Range on HMM: 141-270/270
Sequence Identity: 40% (54 aa)

NILLGIGDRHITVKIANFNFARNL-NGSKYWTVKEDTTLAIKWIAPEAFALKRLSIKSDVWSFGILVWELTTKGKEP-YPGMTKEKVTEAV-SKGYHMPI
|.|..      .|||. |  || . | . | ...... | ||| |||... .. ..||||||||.| ||. | |..| ||||. | | |..  .|| ||.
NCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC

PQDCPEPFKQLMMNCWQNEDDHRPSFKDIFNLL
|..||..  .||. ||. . ..||.|..| . |
PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK415.AA UTK 198-329 35 1.6e-44 150.26 In-house 146-296 (296) Show / Hide 
Range on Protein: 198-329
Range on HMM: 146-296/296
Sequence Identity: 35% (55 aa)

AENILLGIGDRH-------ITVKIANFN---FARNLN---------GSKYWTVKEDTTLAIKWIAPEAFALK-RLSIKSDVWSFGILVWELTTKGKEPYP
| |.|.   ..|        ..|||.|    ..|..|         .| | .  ... ..|.| ||||..   | ..||||||||...||. | |. |||
ARNCLV---HMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYP

GMTKEKVTEAVSKG--YHMPIPQDCPEPFKQLMMNCWQNEDDHRPSFKDIFNLL
||. ..|...|..|  |.|| |.|||.|  .||. ||. . . ||.|.|.   .
GMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK415.AA TK 198-329 23 3.4e-43 142.17 In-house 268-486 (486) Show / Hide 
Range on Protein: 198-329
Range on HMM: 268-486/486
Sequence Identity: 23% (52 aa)

AENILLGIGDRH--------ITVKIANFN--------FARNL-NGSKYWTVKE-----------------------DTTLAIKWIAPEAFA---------
| |.|.| ...          ..||| |          || . ... |.....                       .. | |.| |||...         
ARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEK

LKRLSIKSDVWSFGILVWELTTKGKEPYPG-MTK---------EKVTEAVSKG--------------YHMPIPQDCP--------------EPFKQLMMN
 .. ..||||||||.|.||. | |.|||.| |.          . | | . .|              . || |..||              | . .||. 
YGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQ

CWQNEDDHRPSFKDIFNLL
||. . ..||.|... . |
CWHYDPEDRPTFSQLHEQL
Kinase AqueK415.AA Frk 198-333 40 2.9e-39 133.56 In-house 126-260 (260) Show / Hide 
Range on Protein: 198-333
Range on HMM: 126-260/260
Sequence Identity: 40% (56 aa)

AENILLGIGDRHITVKIANFNFARNLNGSKY--WTVKEDTTLAIKWIAPEAFALKRLSIKSDVWSFGILVWELTTKGKEPYPGMTKEKVTEAVSKGYHMP
| |.|.|    |  .||| |  || |   .   .  . .  . ||| ||||   .. .|||||||||||. |. | |. ||||||  .| . |..|| ||
ARNVLVG---EHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMP

IPQDCPEPFKQLMMNCWQNEDDHRPSFKDIFNLLIKYD
 | .||. . ..|..||. . ..|| |  .   | .| 
QPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK415.AA Abl 205-329 43 5.9e-39 127.27 In-house 130-252 (252) Show / Hide 
Range on Protein: 205-329
Range on HMM: 130-252/252
Sequence Identity: 43% (54 aa)

IGDRHITVKIANFNFARNLNGSKYWTVKEDTTLAIKWIAPEAFALKRLSIKSDVWSFGILVWELTTKGKEPYPGMTKEKVTEAVSKGYHMPIPQDCPEPF
.|. || ||.| |  || ...  | | .      ||| |||. | .. |.||||| ||.|.||. | |  ||||.  ..| . . ||| |  |. ||.  
VGEHHI-VKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKV

KQLMMNCWQNEDDHRPSFKDIFNLL
 .|| .||| .   |||||.| . .
YELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK415.AA SrcB 213-330 44 2.4e-37 123.84 In-house 135-251 (251) Show / Hide 
Range on Protein: 213-330
Range on HMM: 135-251/251
Sequence Identity: 44% (53 aa)

KIANFNFARNLNGSKYWTVKEDTTLAIKWIAPEAFALKRLSIKSDVWSFGILVWELTTKGKEPYPGMTKEKVTEAVSKGYHMPIPQDCPEPFKQLMMNCW
||| |  || ..   | | .|     ||| ||||       |||||||||||. |. | |. ||||||   | .....|| || |. |||   ..|| ||
KIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPGMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCW

QNEDDHRPSFKDIFNLLI
..  . || |  .   | 
KERPEERPTFDYLQSVLD
Kinase AqueK415.AA Src-Unclassified 212-329 40 4.8e-37 124.52 In-house 163-284 (284) Show / Hide 
Range on Protein: 212-329
Range on HMM: 163-284/284
Sequence Identity: 40% (49 aa)

VKIANFNFAR-NLNGSKYWTVKEDTTLAIKWIAPEAFALKRLSIKSDVWSFGILVWELTTKGKEPYPGMTKEKVTEAVSKGYHMPIP--QDCPEPFKQ-L
||.. |  ||  | .      . .  . .|| |||.|     ||||||||.||| ||. |||. |||||  . | | |. || || |  . ||.   . .
VKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDI

MMNCWQNEDDHRPSFKDIFNLL
|  ||    . || |   .. .
MKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK415.AA Src-Echino1 195-329 40 1.6e-35 120.52 In-house 121-252 (252) Show / Hide 
Range on Protein: 195-329
Range on HMM: 121-252/252
Sequence Identity: 40% (55 aa)

NVVAENILLGIGDRHITVKIANFNFARNLNGSKYWTVKEDTTLAIKWIAPEAFALKRLSIKSDVWSFGILVWELTTKGKEPYPGMTKEKVTEAVSKGYHM
.. | |.|.| |.    .|||.|  || ..   | . .    | ||| ||||    |  |||||||||||. |. | |. |||||..  |.. | .|| |
DLAARNVLVGKGN---VCKIADFGLARMMQKDVYCGKQ-GAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPGMMNREVLDQVDRGYRM

PIPQDCPEPFKQL-MMNCWQNEDDHRPSFKDIFNLL
| ...||.   .. || ||  .   || |. . . .
PKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
TyrKc AqueK415.AA TyrKc 161-329 22 4.6e-15 20.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 161-329
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

IKFSQCINAGQFGETWKGNCKGKGPVIIKTNI--------------ATN------------VVAE-----------------------------------
|.. . .  |.||| .||  |   .| .|.                               |. .                                   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC

-------------------------------NILLGIGDRHITVKIANFNFARNLNGS-------KYWTVKE--DTT--LAIKWIAPEAFALKRLSIKSD
                               |.|.| .    ||||. |  .|..          .| ..||  ..   | |.| |||..  .. ..|||
MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGILVWELTTKGKEPYPG-----MTKEKVTEAVSKGYHMPIPQD--------CPEPFKQLMMNCWQNEDDHRPSFKDIFNLL
|||||.. ||. | |..||||     |. . | | | .|| ||.|..        ||.   |.|  ||. . . ||.|..|  ..
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK415.AA Pkinase 241-329 18 3.7e-09 33.46 Pfam 177-293 (293) Show / Hide 
Range on Protein: 241-329
Range on HMM: 177-293/293
Sequence Identity: 18% (22 aa)

WIAPEAFA-LKRLSIKSDVWSFGILVWELTTKGKEPYPGM-------TKEKVTEAVSKGYHMPIPQDCP-------------------EPFKQLMMNCWQ
..|||     .  . |.|.||.|....|. . |. |.||         .... .  .. .| ..|..|.                   |..|... .|..
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

NEDDHRPSFKDIFNL--L
     ||....|..   .
KDPKKRPTAEQILQHPWF
Kinase AqueK415.AA S_TKc 161-331 14 6.8e-07 -75.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 161-331
Range on HMM: 1-231/231
Sequence Identity: 14% (37 aa)

IKFSQCINAGQFGETWKGNCKG-KGPVIIK----------------------------------------T---NIATNVVA------------------
 .. . |  | ||. .|.  |. .  | ||                                        .   .  .  .                   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

----------------------ENILLGIGDRHITVKIANFNFARNLNGSKYWTVKEDTTLAIKWIAPEAFALKRLSI-KSDVWSFGILVWELTTKGKEP
                      |||||       ..||. | .|| |                 ..||| .     .  |.|.||.|....|. . |. |
YQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPP

YPGMTKEKVTEAVSKGYHMPIPQDCPEPFKQLMMNCWQNEDDHRPSFKDIFN-------LLIK
.|  . ... . .            ....|.....|.| . ..||.  ....           
FP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK415.AA SFK-Src 161-190 36 6e-06 13.04 In-house 1-30 (259) Show / Hide 
Range on Protein: 161-190
Range on HMM: 1-30/259
Sequence Identity: 36% (11 aa)

IKFSQCINAGQFGETWKGNCKGKGPVIIKT
|.  .   .||||. |||   ..  | .||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKT
Kinase AqueK415.AA Frk 161-190 40 1.3e-05 15.08 In-house 1-30 (260) Show / Hide 
Range on Protein: 161-190
Range on HMM: 1-30/260
Sequence Identity: 40% (12 aa)

IKFSQCINAGQFGETWKGNCKGKGPVIIKT
|.. . . .||||| | |    . || .||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKT
Kinase AqueK415.AA SrcB 161-190 40 6.6e-05 12.43 In-house 1-30 (251) Show / Hide 
Range on Protein: 161-190
Range on HMM: 1-30/251
Sequence Identity: 40% (12 aa)

IKFSQCINAGQFGETWKGNCKGKGPVIIKT
.|. . . |||||| | |  ...  | .||
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKT
Kinase AqueK415.AA Src-Echino1 161-190 40 0.000129 11.35 In-house 1-30 (252) Show / Hide 
Range on Protein: 161-190
Range on HMM: 1-30/252
Sequence Identity: 40% (12 aa)

IKFSQCINAGQFGETWKGNCKGKGPVIIKT
 .. . |  |..|| |||  .|  || .||
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKT
Kinase AqueK415.AA Src 161-190 43 0.000245 10.59 In-house 1-30 (255) Show / Hide 
Range on Protein: 161-190
Range on HMM: 1-30/255
Sequence Identity: 43% (13 aa)

IKFSQCINAGQFGETWKGNCKGKGPVIIKT
||. . . .||||| |.|  .|. .| .||
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKT
Kinase AqueK415.AA SrcA 161-190 40 0.001218 6.86 In-house 1-30 (250) Show / Hide 
Range on Protein: 161-190
Range on HMM: 1-30/250
Sequence Identity: 40% (12 aa)

IKFSQCINAGQFGETWKGNCKGKGPVIIKT
|.  . .  |.||| | |   |.  | |||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKT
Kinase AqueK415.AA TK 161-190 20 0.017374 3.29 In-house 1-59 (486) Show / Hide 
Range on Protein: 161-190
Range on HMM: 1-59/486
Sequence Identity: 20% (12 aa)

IKFSQCINAGQFG---ETWKGNCKGKG--------------------------PVIIKT
|.. . . .||||   | .||  .|..                          || .|.
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKM
Kinase AqueK415.AA Src-Unclassified 161-190 40 0.019394 4.1 In-house 1-30 (284) Show / Hide 
Range on Protein: 161-190
Range on HMM: 1-30/284
Sequence Identity: 40% (12 aa)

IKFSQCINAGQFGETWKGNCKGKGPVIIKT
..    .  ||||| |.|  .||  | .||
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKT
Kinase AqueK415.AA Pkinase_Tyr 161-190 37 0.035113 8.01 Pfam 1-35 (270) Show / Hide 
Range on Protein: 161-190
Range on HMM: 1-35/270
Sequence Identity: 37% (13 aa)

IKFSQCINAGQFGETWKGNCK-----GKGPVIIKT
|.| . . .|.||| .|| .|     .| || .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKM