Gene AqueK411 (A.queenslandica)

AqueK411

Species: A.queenslandica
Alias: AqueK411
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Frk

Sequence

Name Sequence Type Origin Length Description Download
AqueK411.AA Protein None 632 None Fasta, JSON
AqueK411.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of AqueK411.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 AqueK411.AA SH3 185-242 41 5.9e-26 93.46 SMART 1-58 (58) Show / Hide 
Range on Protein: 185-242
Range on HMM: 1-58/58
Sequence Identity: 41% (24 aa)

PVYIALFDYDQRTSEDLSFRKGERLEILNDQDGDWWQAKSLDTGKEGYIPSNYVAEYK
|...||.||. .....|||.||. ...|.. |..||...  .||.||..|||||.|..
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK411.AA SH3_1 188-235 38 1.2e-24 85.9 Pfam 1-49 (49) Show / Hide 
Range on Protein: 188-235
Range on HMM: 1-49/49
Sequence Identity: 38% (19 aa)

IALFDYDQRTSEDLSFRKGERLEILNDQDG-DWWQAKSLDTGKEGYIPS
.||.||.......|||.||. .......|. ||| .....||.||..||
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 AqueK411.AA SH3_2 186-241 22 4.7e-15 55.62 Pfam 1-68 (68) Show / Hide 
Range on Protein: 186-241
Range on HMM: 1-68/68
Sequence Identity: 22% (15 aa)

VYIALFDYDQ-RTSED-----LSFRKGERLEIL---NDQDGDWWQA-KSLDTGKE--GYIPSNYVAEY
.|....||.  .  ..     |.|.||. ....   .  ...||..  ....|..  |..||..|.|.
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK411.AA SH2 249-325 56 3.9e-47 140.21 Pfam 1-81 (81) Show / Hide 
Range on Protein: 249-325
Range on HMM: 1-81/81
Sequence Identity: 56% (46 aa)

WYFGPIKRAEAEKLLRA-TTMRGTFLVRESESKPGDYSLSIQDIE---TVKHYRIRKLDEGGFFITRRAVFNTLKELVEYY
||.|.| |.|||.||.. . ..||||||||||.||||.||  |      ||||||...|.||..|| |  |..| ||||.|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK411.AA SH2 247-331 47 1.5e-37 132.02 SMART 1-87 (87) Show / Hide 
Range on Protein: 247-331
Range on HMM: 1-87/87
Sequence Identity: 47% (42 aa)

EDWYFGPIKRAEAEKLLRAT-TMRGTFLVRESESKPGDYSLSIQDIETVKHYRIRKLDEGGFFITR--RAVFNTLKELVEYYMKDSDG
. ||.|.| |.|||.||..     |.||||.|||.||||.||. . . |||||||..|.|...|.   |  |..| |||..|.. ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK411.AA SFK-Src 365-619 68 2.1e-211 633.56 In-house 1-259 (259) Show / Hide 
Range on Protein: 365-619
Range on HMM: 1-259/259
Sequence Identity: 68% (178 aa)

ITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGTMQPQAFLEEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKGALLSFLQSSEGRRLQLPQLID
| | . || ||||.|. | ||||| ||||||| |.|  . ||.|| .|||||||.|||||||||   |||||||||  | || .|.. .|| |..|||.|
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLIA-DDE-YNAHEGAKFPIKWTAPEAALYNRFSIKSDVWSFGVLLTELVTYGRIPY
||||.|.||||||  |..||||||||.|||.||.|||.|||..| .| ||| | ||||||||||||||||...|||||||||||||.|..|.||||||||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMSNAEVLQQLER--GYRMPCPPNTHESLYQIMLDCWKRNPADRPTFEALQWRLEDFF
|||.|.|||||..|  |||||||||. . .|.||.|||. .| |||||| |.|..||||
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK411.AA Src 365-615 72 1.6e-193 649.19 In-house 1-255 (255) Show / Hide 
Range on Protein: 365-615
Range on HMM: 1-255/255
Sequence Identity: 72% (185 aa)

ITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGTMQPQAFLEEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKGALLSFLQ-SSEGRRLQLPQLI
|.|.| ||.||||||..|.||..|.||||||| |||.|.|||.|| |||||||.||.||||||..|.||||.||.| .| || .|. ..|||.|.|||||
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLIA--DDEYNAHEGAKFPIKWTAPEAALYNRFSIKSDVWSFGVLLTELVTYGRIP
|||||.|.||||||  |||||||||||.||||||.||||||||||||   ||||.|..|||||||||||||..|.||.|||||||||.||||.|||||.|
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMSNAEVLQQLERGYRMPCPPNTHESLYQ-IMLDCWKRNPADRPTFEALQWRL
||||.|.|||||.|||||||||.|  ..||. ||| ||.. | .||||| ||| |
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK411.AA Frk 365-619 71 4.3e-169 568.05 In-house 1-260 (260) Show / Hide 
Range on Protein: 365-619
Range on HMM: 1-260/260
Sequence Identity: 71% (187 aa)

ITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGTMQPQAFLEEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKGALLSFLQ--SSEGRRLQLPQL
| |.| ||.||||||.||||||||||||||||.||| |. || || |||||||||||||||||| |.||||||||| .|.|. .||  . .||..|..||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

IDMAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLAR-LIADDE--YNAHEGAKFPIKWTAPEAALYNRFSIKSDVWSFGVLLTELVTYGR
.|||||.|||||||| .|||||||||||.||||.||||.||||||| |. |.|  | .. ||.||||||||||| ||.|.|||||||||.||||..||||
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

IPYPGMSNAEVLQQLERGYRMPCPPNTHESLYQIMLDCWKRNPADRPTFEALQWRLEDFF
.||||| ||||||....|||||.|||  . ||.|||.||. .|  ||||| |||.|||.|
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK411.AA SrcA 365-615 70 4.2e-167 532.47 In-house 1-250 (250) Show / Hide 
Range on Protein: 365-615
Range on HMM: 1-250/250
Sequence Identity: 70% (177 aa)

ITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGTMQPQAFLEEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKGALLSFLQSSEGRRLQLPQLID
|.| | ||.|.||||. | || || ||.|||| ||| |.|||||| ||||||| ||.|||||   |.||||.|| | ||.|| ||.  ||. |.||||.|
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

MAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLIADDEYNAHEGAKFPIKWTAPEAALYNRFSIKSDVWSFGVLLTELVTYGRIPYPG
||||.|.||||.|  ||||||| | ||||||| |||.||||||||| |.||.|. |||||||||||||||| || |||||||||.||||||| ||.||||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG

MSNAEVLQQLERGYRMPCPPNTHESLYQIMLDCWKRNPADRPTFEALQWRL
| | |||.| ||||.||||..  |||...|  ||...| .||||| ||  |
MNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK411.AA Pkinase_Tyr 365-615 50 1.7e-159 540.81 Pfam 1-270 (270) Show / Hide 
Range on Protein: 365-615
Range on HMM: 1-270/270
Sequence Identity: 50% (137 aa)

ITLLRLLGTGQFGEVYEGLWN-----NTTPVAVKTLKTGTMQP----QAFLEEAHIMKKL-RHPKLIQLYAVCT-KEDP--IYIITELMPKGALLSFLQS
||... || |.|||||.| |.     ...|||||.|| |.|..    ..|..|| |||.| .||....||.||| ...|  |||..|.||.| ||..|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

S--EGRRLQLPQLIDMAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLI-ADDEY-NAHEGAKFPIKWTAPEAALYNRFSIKSDVWSF
   ....| ...|..|..|||.||.||| .|.|||||||||.||.|||..|..||||||.|  ||.|  ...|.|.||||.|||.  |..|..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GVLLTELVTYGRIP-YPGMSNAEVLQQL-ERGYRMPCPPNTHESLYQIMLDCWKRNPADRPTFEALQWRL
|||. |..|||..| ||||||.||.... |.|||||||.|... .|..|..||. .|.|||||......|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK411.AA Src-Unclassified 365-619 48 2.8e-149 502.23 In-house 1-284 (284) Show / Hide 
Range on Protein: 365-619
Range on HMM: 1-284/284
Sequence Identity: 48% (141 aa)

ITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTG---TMQPQAFL--------EEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKGALLSFLQSSE
. ||| || ||||||. | | .   |||||.. |   || | |||        .|| ||||.||..|..|||||..| |.|||||.| .| || .|.   
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

GRRLQLPQL------------IDMAAQIAAGMAYLEMHNYIHRDLAARNILVGENN-----ICKVADFGLA--RLIADDEYNAHEGAKFPIKWTAPEAAL
|. | .. .            .|.|||.| || |||   |.||||||||.|.|.||     . ||.|||||  .|..||.| .  ||.||.||.|||...
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YNRFSIKSDVWSFGVLLTELVTYGRIPYPGMSNAEVLQQLERGYRMPCP--PNTHESLYQ-IMLDCWKRNPADRPTFEALQWRLEDFF
|  |||||||||.|.|| |. |.|..||||| | ||| ..||||||| |      ...|. ||. ||   |  ||||.    .|  .|
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFD----TLYHYF
Kinase AqueK411.AA TyrKc 365-615 44 3.7e-148 499.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 365-615
Range on HMM: 1-280/280
Sequence Identity: 44% (128 aa)

ITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGTMQPQAFLEEAHIMKKL--RHPKLIQLYAVCTKE-------DPIYIITELMPKGALLSFLQSSEGR
|||.. || |.|||||.| |.  ..||||.|| ..   ..|..|| ||.||  .|| ...||.|||..       .|..|..|.||.|.|...|......
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

RLQLPQLIDMAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLIADD--------EYNAHE--GAK--FPIKWTAPEAALYNRFSIKSD
 |....|.... |||.||.||. .|.|||||||||.|||||...|..||||.| | ||         | . |  |.|  .||.|.|||.  |..|..|||
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGVLLTELVTYGRIPYPG-----MSNAEVLQQLERGYRMPCPPN--------THESLYQIMLDCWKRNPADRPTFEALQWRL
||||||.. |. |||  ||||     |||.||......|||||.|||         .. .||||..||...|.|||||...  ..
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK411.AA SrcB 365-616 65 1.8e-146 492.89 In-house 1-251 (251) Show / Hide 
Range on Protein: 365-616
Range on HMM: 1-251/251
Sequence Identity: 65% (165 aa)

ITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGTMQPQAFLEEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKGALLSFLQSSEGRRLQLPQLID
. | . ||.||||||. | .|| . |||||.| ||| |.|||.|| .||.| | .|..|||| ||| ||||||| | ||.|| ||.. || .|.||.|||
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLIADDEYNAHEGAKFPIKWTAPEAALYNRFSIKSDVWSFGVLLTELVTYGRIPYPG
|.|||| ||||.| .||||||| | |||| |  .||.|||||||.| |.|| |.||||||||||||||  .  | |||||||||.||.|.||||||||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

MSNAEVLQQLERGYRMPCPPNTHESLYQIMLDCWKRNPADRPTFEALQWRLE
|.|.||...||||||||.| |  | ||.||  |||  | .||||. ||  |.
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK411.AA SRM 366-616 55 1.7e-138 465.98 In-house 2-253 (253) Show / Hide 
Range on Protein: 366-616
Range on HMM: 2-253/253
Sequence Identity: 55% (140 aa)

TLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGT-MQPQAFLEEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKGALLSFLQSSEGRRLQLPQLID
|| | || | ||||.||||    .||.|  |    |. . .  |   |||||| ..| |.|||.  ||.|||||||.|| |. .| .|... |..|.|.|
TLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLD

MAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLIADDEYNAHEGAKFPIKWTAPEAALYNRFSIKSDVWSFGVLLTELVTYGRIPYPG
.| |.| ||.|||  |||||||||||.|||.||.|||.|||||||| || |    . . |.|||||||| |  .|.||||||||.|| |. ||| .||||
FACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPG

MSNAEVLQQLERGYRMPCPPNTHESLYQIMLDCWKRNPADRPTFEALQWRLE
|.| | .|| .||||||||     . .  ||.||.| | .||.| .|  .| 
MTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase AqueK411.AA Src-Echino1 365-615 56 1.1e-132 447.04 In-house 1-252 (252) Show / Hide 
Range on Protein: 365-615
Range on HMM: 1-252/252
Sequence Identity: 56% (142 aa)

ITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGTMQPQAFLEEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKGALLSFLQSSEGRRLQLPQLID
  . . .| |..|||..|.||  ||||||||| .|| | .|| || .|||.||  ..|.||||  ..||||.|||| .| |...|.. .........|||
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLIADDEYNAHEGAKFPIKWTAPEAALYNRFSIKSDVWSFGVLLTELVTYGRIPYPG
| |.||.|| ||.  |..||||||||.|||. |.||.|||||||.. .|.| ...|||.|||||||||||| || |||||||||.|.||.||.||.||||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPG

MSNAEVLQQLERGYRMPCPPNTHESLYQI-MLDCWKRNPADRPTFEALQWRL
| | |||.|..|||||| . .  .|||.. |. || ..|  ||||| |   .
MMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK411.AA TK 365-615 28 1.9e-129 436.38 In-house 1-486 (486) Show / Hide 
Range on Protein: 365-615
Range on HMM: 1-486/486
Sequence Identity: 28% (138 aa)

ITLLRLLGTGQFG---EVYEGLWNNT--------------------------TPVAVKTLKTG-TMQPQA--------------FLEEAHIMKKLR----
|||.. || ||||   |||.|.|..                           ||||||.|| | .|....              |||||..||...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPKLIQLYAVCTKE------------DPIYIITELMPKGA----LLSFLQSSEGR--------------------------------------------
 || ...||.|||..             |..|..|.||.|     |...|... ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------RLQLPQLIDMAAQIAAGMAYLEMH------NYIHRDLAARNILVGENNI-----------CKVADFG---
                              .| ..||. |..|||.||.||. .      |..||||||||.||||||.           ||.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARLI-ADDEYNAHE------------------------GAKFPIKWTAPEAAL---------YNRFSIKSDVWSFGVLLTELVTYGRIPYPG-M
     ||| |  ||.| ...                        |.|.||.|.|||. .         |..|..||||||||||. |..|||. ||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SN---------AEVLQQLERG--------------YRMPCPPNTH--------------ESLYQIMLDCWKRNPADRPTFEALQWRL
||         .||...|.||              .|||.||. .              | .|..|..||...|.|||||..|. .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK411.AA Tec 365-617 46 1.4e-120 406.87 In-house 1-254 (254) Show / Hide 
Range on Protein: 365-617
Range on HMM: 1-254/254
Sequence Identity: 46% (118 aa)

ITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGTMQPQAFLEEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKGALLSFLQSSEGRRLQLPQ--L
.|... ||.|||| |  | | .   ||.|..| |.|    |.||| .|.|| ||||.||| ||... ||||.|| | .| ||..| . .. ..|  .  |
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKH-HFQKNMAIL

IDMAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLIADDEYNAHEGAKFPIKWTAPEAALYNRFSIKSDVWSFGVLLTELVTYGRIPY
..|  ..  |||||| |..||||||||| |||.... ||.|||..| . ||.|    |.|||.|| .||   |.|.| |||||.||||  |  . |..||
LEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPY

PGMSNAEVLQQLERGYRMPCPPNTHESLYQIMLDCWKRNPADRPTFEALQWRLED
. ||| || ..  .|.|.  |    ...|||| .||.  | .||||. |   ...
ENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK411.AA S_TKc 365-619 25 6.5e-59 202.95 SMART 1-231 (231) Show / Hide 
Range on Protein: 365-619
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

ITLLRLLGTGQFGEVYEGLWNN-TTPVAVKTLKTGTMQPQAFLEEAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPK--GALLSFLQSSEGRR----L
 ..||..| | ||.|| . ...    ||.| .|      . .. |  |.|| .|| ...|| |.   | .|...|...   | |......  ...    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

QLPQLIDMAAQIAAGMAYLEMHNYIHRDLAARNILVGENNICKVADFGLARLIADDEYNAHEGAKFPIKWTAPEAALYNRFSI-KSDVWSFGVLLTELVT
   .   ...||. ...|.  |. |||||   |||. |    |..||||||..                . |||      ..  |.|.||.|..| |...
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

YGRIPYPGMSNAEVLQQLERGYRMPCPPNTHESLYQIMLDCWKRNPADRPTFEALQ----WRLEDFF
 |. |.|    .......             ... ...  |....|..||| ||||    ...  .|
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase AqueK411.AA Pkinase 365-619 24 1.5e-46 165.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 365-619
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

ITLLRLLGTGQFGEVYEGLWNNT-TPVAVKTLKTGTMQPQAFLE-----EAHIMKKLRHPKLIQLYAVCTKEDPIYIITELMPKG----ALLSFLQSSEG
....| .| | ||.||.. . .|   ||||..|  .  ..   .     |..|||.|.||  ..|| ... .| ||...|....|     | .... ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RRL--QLPQLIDMAAQIAAGMAYLEMHNYIHRDLAARNILVGENNIC----KVADFGLARLIADDEYNAHEGAKFP---IKWTAPEAAL-YNRFSIKSDV
...  .  ...... ||. |..|.  .. |||||   |||. .|. .    |..|||||...    |   . .. .   . . |||  . ..  . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGVLLTELVTYGRIPYPGM-------SNAEVLQQLERGYRMPCP-------------------PNTHESLYQIMLDCWKRNPADRPTFEALQWRLEDF
||.|..| |... || |.||         .. . . ... .. ..|                   .|..|.. ... .|....|..|||  | |    ..
WSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--AEQILQHPW

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