Gene AqueK410 (A.queenslandica)

AqueK410

Species: A.queenslandica
Alias: AqueK410
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Frk

Sequence

Name Sequence Type Origin Length Description Download
AqueK410.AA Protein None 392 None Fasta, JSON
AqueK410.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of AqueK410.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 AqueK410.AA SH2 5-82 50 1.1e-46 138.89 Pfam 1-81 (81) Show / Hide 
Range on Protein: 5-82
Range on HMM: 1-81/81
Sequence Identity: 50% (41 aa)

WYFGKIKRVDAEKLLQLPINEVGAYLIRDSETNPGDYSLSIRDLE---RVRHYKIKRLDNGTFFITRKATFNTISELVSYY
||.||| | .||.||. | |. |..|.|.||..||||.|| ||     ||.||.|.|.|||...|| . .|....|||..|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK410.AA SH2 3-88 44 1.7e-35 125.19 SMART 1-87 (87) Show / Hide 
Range on Protein: 3-88
Range on HMM: 1-87/87
Sequence Identity: 44% (39 aa)

LMWYFGKIKRVDAEKLLQLPINEVGAYLIRDSETNPGDYSLSIRDLERVRHYKIKRLDNGTFFITR--KATFNTISELVSYYQRQADG
  ||.|.| | .||.||. | .. |..|.||||.|||||.||.|. ..|.||.|.|.|.| ..|.   . .|... ||| .||. ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK410.AA SFK-Src 123-376 66 1e-210 631.49 In-house 1-259 (259) Show / Hide 
Range on Protein: 123-376
Range on HMM: 1-259/259
Sequence Identity: 66% (172 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGTMSPQEFLQEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHGALLDYLRG-DGRSLQQAQLID
|.....||.||||.|| | ||.||.|||||||||.|| .||||||..|||||||.|||||||||  ||||||||||| | |||||.   ||||.  ||.|
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVI-DEDI-YEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPY
| ||||.|||||| ||..||||||||.|||.  .|||.|||..||. ..|. |.||.|||||||||||||. .||| || ||||||| ..|..|||| ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMTNAQTLEAIQQ--GYRMPPPQNCPDKLYSVMLDCWREEPETRPTFETLQWQLEEFY
|||||.  |  . .  ||||| |.||||..| .|.|||..||. |||||.|.||.|.|.
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK410.AA Src 123-372 70 1.4e-190 639.4 In-house 1-255 (255) Show / Hide 
Range on Protein: 123-372
Range on HMM: 1-255/255
Sequence Identity: 70% (179 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGTMSPQEFLQEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHGALLDYLR--GDGRSLQQAQLI
|...|.||.|||||||.|.|||.|.|||||||||||||. ||||| .||||||.||.||||||..||||||.||.|.|| |||||.  |.||.|.  |||
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVID--EDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFP
|| ||||.||||||..|||||||||||.||||...||||||||||.|.  .|.|.|..|||||||||||||. |.|||||.||||||| |.|..|||| |
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMTNAQTLEAIQQGYRMPPPQNCPDKLYS-VMLDCWREEPETRPTFETLQWQL
||||||...|.....||||| |.||||.||  .|| ||...|| |||||.||| |
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK410.AA Frk 123-376 71 2.9e-167 561.96 In-house 1-260 (260) Show / Hide 
Range on Protein: 123-376
Range on HMM: 1-260/260
Sequence Identity: 71% (185 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGTMSPQEFLQEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHGALLDYLR---GDGRSLQQAQL
||. ||||.|||||||||||| || ||||||||||| |..||.|| .||||||||||||||||| |||||||||||.||.|..||.   . ||..|  ||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

IDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLAR-VIDEDI--YEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGR
.|| |||||||||||.||||||||||||.|||||.|||.||||||| .. ...  ||...||.||||||||||| ||.||||.|||||||.|.|.|||||
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

FPYPGMTNAQTLEAIQQGYRMPPPQNCPDKLYSVMLDCWREEPETRPTFETLQWQLEEFY
 ||||||||. |. ...||||| | ||| .||..||.||...|. |||||||||.||...
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK410.AA Pkinase_Tyr 123-372 49 6.30000000001e-159 538.88 Pfam 1-270 (270) Show / Hide 
Range on Protein: 123-372
Range on HMM: 1-270/270
Sequence Identity: 49% (133 aa)

IQMKRRLGAGQFGEVWEGLWN-----GTTQVAVKTLKPGTMSP----QEFLQEAGLMKKL-RHPKLIQLYAVCT-EEEP--IYIITELMKHGALLDYLRG
|.. . ||.|.||||..| |.     ....||||.||.|.|..    ..|..|| .||.| .||....||.||| ..||  |||..|.|.|| |||||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

D---GRSLQQAQLIDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVI-DEDIY-EAHTGAKFPIKWTAPEAAMYNRFTIKADVWSF
    ...|   .|..||.|.|.||.|||..|.|||||||||.||.| ...|..|||||| | ..| |  ...|.|.||||.|||. .|..||.| |||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GIVLYEVITYGRFP-YPGMTNAQTLEAI-QQGYRMPPPQNCPDKLYSVMLDCWREEPETRPTFETLQWQL
|....|..|||. | ||||.|.. .|.| ..|||||.|.||||..|..|..||...|| ||||. ...||
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK410.AA SrcA 123-372 66 1.4e-157 501.87 In-house 1-250 (250) Show / Hide 
Range on Protein: 123-372
Range on HMM: 1-250/250
Sequence Identity: 66% (166 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGTMSPQEFLQEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHGALLDYLR-GDGRSLQQAQLID
|...|||| |.||||| | |||||.||.||||||||||. ||.|| .|||||| ||.|||||   ||||||.|| | .|.|||.|. ..|. |.  ||.|
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYPG
| ||||.||||.|  ||||||| | ||||||.||||.|||||||.|... |.|. ||||||||||||||.| |||||.|||||||.| |..| || ||||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG

MTNAQTLEAIQQGYRMPPPQNCPDKLYSVMLDCWREEPETRPTFETLQWQL
| |   || . .||.|| ||.||  |. .|  ||| .|| ||||| ||  |
MNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK410.AA Src-Unclassified 123-372 48 5.70000000001e-151 507.84 In-house 1-284 (284) Show / Hide 
Range on Protein: 123-372
Range on HMM: 1-284/284
Sequence Identity: 48% (138 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPG---TMSPQEFL--------QEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHGALLDYLRGDG
.. .| || ||||||| | | |   |||||..||   ||||  ||        ||| .|||.||..|..|||||..|||.|||||.|  | ||..|| .|
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

-RSLQQAQL------------IDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHL-----ICKVADFGLA--RVIDEDIYEAHTGAKFPIKWTAPEAAM
 . |    .            .|. |||| || |||   |.||||||||.|.|.       . ||.|||||  ... .|.|.. |||.||.||.|||.. 
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YNRFTIKADVWSFGIVLYEVITYGRFPYPGMTNAQTLEAIQQGYRMPPP--QNCPDKLYS-VMLDCWREEPETRPTFETLQWQL
|  |.|| ||||.|| |.|. |.|. ||||| |  .|| .  ||||| |  . ||| .|  .|. || . |. ||||.||   .
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK410.AA TyrKc 123-372 44 4.7e-144 485.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 123-372
Range on HMM: 1-280/280
Sequence Identity: 44% (125 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGTMSPQEFLQEAGLMKKL--RHPKLIQLYAVCTEE-------EPIYIITELMKHGALLDYLRGDGRS
|.... || |.||||..| |.  .|||||.||...   ..|..|| .|.||  .|| ...||.|||..       ||..|..|.|.||.|.||||  .. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LQQAQLIDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDED--------IYEAHT--GAK--FPIKWTAPEAAMYNRFTIKADV
|. ..|...| |.|.||.||...|.|||||||||.|||| ...|..||||.| |..|         | . .  |.|  .||.|.|||. .|..||.| ||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGIVLYEVITYGRFPYPG-----MTNAQTLEAIQQGYRMPPPQN--------CPDKLYSVMLDCWREEPETRPTFETLQWQL
||||....|. |||  ||||     |.|.. .| ..||||||.|.|        |||..|..|..||.|.|| ||||...  ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK410.AA SrcB 123-373 60 1.4e-143 483.28 In-house 1-251 (251) Show / Hide 
Range on Protein: 123-373
Range on HMM: 1-251/251
Sequence Identity: 60% (153 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGTMSPQEFLQEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHGALLDYLRGD-GRSLQQAQLID
... ..|||||||||| | .|. ..|||||.|.|||||. ||.|| .||.| | .|..|||| | | ||||||| |..|.|||.|. | |  |.  .|||
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYPG
| ||.| ||||.|..||||||| | |||| | |.||.|||||||.|... | |. |||||||||||||  .  ||||.|||||||.|.|..|||| ||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

MTNAQTLEAIQQGYRMPPPQNCPDKLYSVMLDCWREEPETRPTFETLQWQLE
|||.. ......||||| |.|||. || .|  ||.| || ||||. ||  |.
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK410.AA Src-Echino1 123-372 56 4.6e-132 445.05 In-house 1-252 (252) Show / Hide 
Range on Protein: 123-372
Range on HMM: 1-252/252
Sequence Identity: 56% (143 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGTMSPQEFLQEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHGALLDYL-RGDGRSLQQAQLID
 .|....| |..||||.|.||| |.|||||||..|||| .|| || .|||.||  ..|.|||| ..|||||.||||..| |.||| ||... .. ..|||
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYPG
| |..|.|| ||...|..||||||||.|||.  .||.|||||||....|.| .. |||.||||||||||.| |||||.|||||||.. |..|.||.||||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPG

MTNAQTLEAIQQGYRMPPPQNCPDKLYSV-MLDCWREEPETRPTFETLQWQL
|.| . |. ...||||| ...||| || . |. ||  .|  ||||| |   .
MMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK410.AA SRM 124-373 53 1.8e-131 442.1 In-house 2-253 (253) Show / Hide 
Range on Protein: 124-373
Range on HMM: 2-253/253
Sequence Identity: 53% (135 aa)

QMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGT-MSPQEFLQEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHGALLDYLR-GDGRSLQQAQLID
 . |.||.| ||||||||| |  .||.|  |    |  ... .|   |||||| ..| |.|||.  .|.|||||||. | |. |||  |.. |.  .|.|
TLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLD

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYPG
.  ||| ||.||| ||||||||||||.|||. ..|||.|||||| | .|||    . . |.|||||||| |  . .| ||||||| |.|. |||  ||||
FACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPG

MTNAQTLEAIQQGYRMPPPQNCPDKLYSVMLDCWREEPETRPTFETLQWQLE
|||  |.  |. ||||| |  ||   .  ||.||. .|| ||.| .|  .| 
MTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase AqueK410.AA TK 123-372 26 1.2e-127 430.24 In-house 1-486 (486) Show / Hide 
Range on Protein: 123-372
Range on HMM: 1-486/486
Sequence Identity: 26% (130 aa)

IQMKRRLGAGQFG---EVWEGLWNGT--------------------------TQVAVKTLKPG-TMSPQE--------------FLQEAGLMKKLR----
|.. . ||.||||   ||..|.|.|                           |.||||.||.| .||..|              ||.||  ||...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPKLIQLYAVCTEE------------EPIYIITELMKHGA----LLDYLRGDGR---------------------------------------------
 || ...||.|||..            ||..|..|.|.||     |.||||   .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------SLQQAQLID-------------------MCAQVAAGMAYLEQQ------NYIHRDLAARNILVGEHLI-----------CKVADFG----
          .|....|..                   ||.|.|.||.||...      |..||||||||.||||...           ||.||||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LARVIDED-IYEAHT------------------------GAKFPIKWTAPEAAM---------YNRFTIKADVWSFGIVLYEVITYG-RFPYPGMT
    ||| |..|  | ...                        |.|.||.|.|||. .         |..||.| ||||||....|. |||   .|.||.
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------AQTLEAIQQG--------------YRMPPPQNCP--------------DKLYSVMLDCWREEPETRPTFETLQWQL
|         .. .| ...|              .|||.|..||              . .| .|..||...|| ||||..|. ||
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK410.AA Tec 123-374 46 5.1e-126 424.95 In-house 1-254 (254) Show / Hide 
Range on Protein: 123-374
Range on HMM: 1-254/254
Sequence Identity: 46% (119 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGTMSPQEFLQEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHGALLDYLRGDGRSLQQAQ--LI
. . . || |||| |  | | .  .||.|..| |.||  .|..||  |.|| ||||.||| ||... ||||.|| |.|| ||.|||  .  .|...  |.
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

DMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYP
.|| .|  ||||||....||||||||| |||.  . ||.|||..| .  | |   .|.|||.|| .||  .|.|.  | |||.||.   || . |. ||.
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE

GMTNAQTLEAIQQGYRMPPPQNCPDKLYSVMLDCWREEPETRPTFETLQWQLEE
 |.| .. |...||.|.  |. |....| .| .||.|.|| ||||. |  |..|
NMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK410.AA S_TKc 123-376 25 4.8e-53 183.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 123-376
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

IQMKRRLGAGQFGEVWEGLWNG-TTQVAVKTLKPGTMSPQEFLQEAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKH--GALLDYLRGDGRS-----L
 .. | .| | ||.|. . ...   .||.| .|      . ...|  ..|| .|| ...|| |. . . .|...|.. .  | |.||..  ||      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

QQAQLIDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTI-KADVWSFGIVLYEVIT
   .   ...|.. ...|. ... |||||   |||. |    |..||||||..        |       . |||      ..  |.|.||.|..||| ..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

YGRFPYPGMTNAQTLEAIQQGYRMPPPQNCPDKLYSVMLDCWREEPETRPTFETLQ----WQLEEFY
 |. |.|  . ..... |            .. . . .  |.. .|| ||| | ||    . . .. 
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase AqueK410.AA Pkinase 123-366 24 6.3e-48 170.34 Pfam 1-285 (293) Show / Hide 
Range on Protein: 123-366
Range on HMM: 1-285/293
Sequence Identity: 24% (72 aa)

IQMKRRLGAGQFGEVWEGLWNGTTQ-VAVKTLKPGTMSPQEFLQ-----EAGLMKKLRHPKLIQLYAVCTEEEPIYIITELMKHG----ALLDYLR-GDG
.. .|..|.| ||.|... . || . ||||..|  . ....  .     |. .||.|.||  ..|| .....  ||...|.. .|     | ||..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RSL--QQAQLIDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLIC----KVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAM-YNRFTIKADVWSF
...  .  ...... |.. |..|. ... |||||   |||. ..  .    |..|||||...|.  ..  |.    . . |||  . ..  . |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIVLYEVITYGRFPYPGM----TNAQTLEAIQQGYRMPPPQNCP-----------------------DKLYSVMLDCWREEPETRPTFE
|..|||... ||.|.||     . .  .. |..  . |.. ..|                       . . ... .|..  |. |||.|
GCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE