Gene AqueK409 (A.queenslandica)

AqueK409

Species: A.queenslandica
Alias: AqueK409
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Frk

Sequence

Name Sequence Type Origin Length Description Download
AqueK409.AA Protein None 517 None Fasta, JSON
AqueK409.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of AqueK409.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 AqueK409.AA SH3 70-127 37 2.4e-20 74.82 SMART 1-58 (58) Show / Hide 
Range on Protein: 70-127
Range on HMM: 1-58/58
Sequence Identity: 37% (22 aa)

PKFIARFKYMARTAEDLSFQKGERLVVIGPLEGDWWMARSLATGSEGYIPRNYVAPIE
|...| . | |.....|||.||. . |.   ...|| .|   || ||..| |||..|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK409.AA SH3_1 73-120 38 7.7e-17 59.75 Pfam 1-49 (49) Show / Hide 
Range on Protein: 73-120
Range on HMM: 1-49/49
Sequence Identity: 38% (19 aa)

IARFKYMARTAEDLSFQKGERLVVIGPLEG-DWWMARSLATGSEGYIPR
.| . |.|.....|||.||. . ||   .. ||| .|.. || ||..| 
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 AqueK409.AA SH3_2 71-126 19 2.1e-11 42.86 Pfam 1-68 (68) Show / Hide 
Range on Protein: 71-126
Range on HMM: 1-68/68
Sequence Identity: 19% (13 aa)

KFIARFKYMA-RTAED-----LSFQKGERLVVI---GPLEGDWWMA-RSLATGSE--GYIPRNYVAPI
.... ..| . . ...     |.|.||. ..||   .   ..|| . .....| .  |..|...|...
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK409.AA SH2 134-211 51 2.7e-41 123.07 Pfam 1-81 (81) Show / Hide 
Range on Protein: 134-211
Range on HMM: 1-81/81
Sequence Identity: 51% (42 aa)

WYFGDIARAEAEKLLMISTNVQGTFLLRISSSQKDALSLSLRDVD---GVKHYRIRKMDDGGFFITTRAVFNTLQEMVRHY
||.|.| |.|||.||| ..|  ||||.| |.|..   .||.|| .    ||||||...|.||..||.|  |..|||.| ||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK409.AA SH2 132-217 43 9.1e-32 112.78 SMART 1-87 (87) Show / Hide 
Range on Protein: 132-217
Range on HMM: 1-87/87
Sequence Identity: 43% (38 aa)

EDWYFGDIARAEAEKLLMISTNVQGTFLLRISSSQKDALSLSLRDVDGVKHYRIRKMDDGGFFITT--RAVFNTLQEMVRHYMMEADG
. ||.|.| |.|||.||.   .  |.||.| |.|.. ...||.|. ..|||||||. |||...|..  |  |..| |.|.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK409.AA SFK-Src 250-504 61 4.2e-189 566.22 In-house 1-259 (259) Show / Hide 
Range on Protein: 250-504
Range on HMM: 1-259/259
Sequence Identity: 61% (160 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGTMEVNDFVKEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHGSLLDYLRNGKGRYVNVHQMID
 .  ||||.| ||.|| | ||.|| ||.||||||.|  . | .|||||||  || | |||||||  |||||.||||  |||||||.. .||  .. |..|
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVI-KEDI-YSPKEGAKFPIKWTAPEAALYSRFTIKSDVWSFGVLVAEVVTKGAMPY
| ||. .||||||.  ..||||||||.|||. | |||.|||..||. ..|. | ..||||||||||||||....|| |||||||||.|  |.|| | .||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMTNRQVLESVEA--GYRMPKPDTCPDPLYSIMMECWRHEPDDRPTFESLKYRLDDYY
|||||  ||  |.   |||||.|  ||| .| ||..||.|||||||||||||....|..
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK409.AA Src 250-500 65 6.8e-182 610.56 In-house 1-255 (255) Show / Hide 
Range on Protein: 250-500
Range on HMM: 1-255/255
Sequence Identity: 65% (167 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGTMEVNDFVKEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHGSLLDYLR-NGKGRYVNVHQMI
... .|||||.||||| |.|| .|.||.||||||||....| .|||.|||  |..|.||||||. |||||||||.||||||||||. .|.||.... | |
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVIK--EDIYSPKEGAKFPIKWTAPEAALYSRFTIKSDVWSFGVLVAEVVTKGAMP
|| ||...||||||.  ||||||||||.||||.| ||||||||||.||  .|.|....|||||||||||||..| ||||||||||||.|  |.||.| .|
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMTNRQVLESVEAGYRMPKPDTCPDPLYS-IMMECWRHEPDDRPTFESLKYRL
||||||..||. ||.|||||.|..||| ||  ||..||. .|..||||| |   |
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK409.AA Frk 250-504 64 5.2e-154 517.95 In-house 1-260 (260) Show / Hide 
Range on Protein: 250-504
Range on HMM: 1-260/260
Sequence Identity: 64% (167 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGTMEVNDFVKEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHGSLLDYLR--NGKGRYVNVHQM
.|. ..|| | ||||| |||| |||||.||||||||. |||..|||.|||. || |.|||||||.||||||.|||| ||||..||.  |.||| ....|.
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

IDMIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLAR-VIKEDI--YSPKEGAKFPIKWTAPEAALYSRFTIKSDVWSFGVLVAEVVTKGA
.|| ||. .||||||.. ||||||||||.||||.|.||.||||||| ..|...  |  . ||.||||||||||| |..|||||||||||.|. |..| | 
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

MPYPGMTNRQVLESVEAGYRMPKPDTCPDPLYSIMMECWRHEPDDRPTFESLKYRLDDYY
||||||||..||. |..|||||.|  ||  ||.||.|||...|. ||||| |...|.||.
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK409.AA SrcA 250-500 62 9.80000000001e-154 489.49 In-house 1-250 (250) Show / Hide 
Range on Protein: 250-500
Range on HMM: 1-250/250
Sequence Identity: 62% (157 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGTMEVNDFVKEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHGSLLDYLRNGKGRYVNVHQMID
..  ..|||| ||||| | || || |||||||||||  . |..|||.|||..|  | |||||   ||||||||| |..|||||.|....|.|. . |..|
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

MIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVIKEDIYSPKEGAKFPIKWTAPEAALYSRFTIKSDVWSFGVLVAEVVTKGAMPYPG
| ||. .||||.|   |||||| | ||||||   ||.|||||||.|... | .. |||||||||||||||| ||||||||||||.|  |.|||| .||||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG

MTNRQVLESVEAGYRMPKPDTCPDPLYSIMMECWRHEPDDRPTFESLKYRL
| || ||| || ||.|| |. ||  |. .|..||| .|..||||| |.  |
MNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK409.AA Pkinase_Tyr 250-500 50 1.4e-149 507.2 Pfam 1-270 (270) Show / Hide 
Range on Protein: 250-500
Range on HMM: 1-270/270
Sequence Identity: 50% (135 aa)

LQFNKKLGQGNFGEVWSGLWN-----ETTPVAIKTLKPGTMEVN----DFVKEAQVMKKI-HHPHLLQLYAVCT-LEEP--IYIVTELMSHGSLLDYLRN
..|.||||.|.||||. | |.     ...|||.|.||.|.|. .    || .||..||.. |||....||.|||  .||  ||||.|.| ||.||||||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

G--KGRYVNVHQMIDMIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVI-KEDIY-SPKEGAKFPIKWTAPEAALYSRFTIKSDVWSF
    .. ........| .||..||.|||.. .|||||||||.||.|.| .|..|||||| | ..| |   ..|.|.||||.|||.  |..||.|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GVLVAEVVTKGAMP-YPGMTNRQVLESV-EAGYRMPKPDTCPDPLYSIMMECWRHEPDDRPTFESLKYRL
|||  |..| |..| ||||.| .|.| . | |||||.|. |||..|..|..||...|.|||||. .  .|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK409.AA Src-Unclassified 250-499 49 9.20000000001e-145 487.22 In-house 1-284 (284) Show / Hide 
Range on Protein: 250-499
Range on HMM: 1-284/284
Sequence Identity: 49% (140 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPG---TMEVNDFV--------KEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHGSLLDYLRNGK
..  .|||.|.||||| | |     ||.||..||   ||    |         .|||.|||  |. | .|||||. |||.||.||.|. ||||..|| | 
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

GRYVNVHQM------------IDMIAQISSGMAYLEEHSYIHRDLAARNILVGEGNS-----CKVADFGLA--RVIKEDIYSPKEGAKFPIKWTAPEAAL
|.|     |            .|. ||. ||| |||.  |.||||||||.|.|. ||      ||.|||||  ... .|.| .. ||.||.||.|||...
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YSRFTIKSDVWSFGVLVAEVVTKGAMPYPGMTNRQVLESVEAGYRMPKP--DTCPDPLYS-IMMECWRHEPDDRPTFESL-KYR
|  |.|||||||.|.|  |. |||  ||||| || ||| || |||||||    ||| .|  ||  ||   |. ||||. | .| 
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK409.AA TyrKc 250-500 43 8.99999999999e-141 474.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 250-500
Range on HMM: 1-280/280
Sequence Identity: 43% (125 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGTMEVNDFVKEAQVMKKI--HHPHLLQLYAVCTLE-------EPIYIVTELMSHGSLLDYLRNGKGR
....|||| |.||||. | |.  ..||.|.||...  . || .||..|.|.  |||....||.||| .       ||..||.|.|.||.|.||||. ...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

YVNVHQMIDMIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVIKED--------IYSPKE--GAK--FPIKWTAPEAALYSRFTIKSD
 ... .....  ||..||.||... .|||||||||.||||.. .|..||||.| |..|         |..||  |.|  .||.|.|||.  |..||.|||
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGVLVAEVVTKGAMPYPG-----MTNRQVLESVEAGYRMPKPDT--------CPDPLYSIMMECWRHEPDDRPTFESLKYRL
||||||.  |. | |..||||     |.|..|.| |..|||||.|.         ||| .|.|| .||...|.|||||. .. ..
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK409.AA Src-Echino1 250-500 61 4.90000000001e-135 454.9 In-house 1-252 (252) Show / Hide 
Range on Protein: 250-500
Range on HMM: 1-252/252
Sequence Identity: 61% (154 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGTMEVNDFVKEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHGSLLDYLRNGKGRYVNVHQMID
|...||.|.|..|||| |.||  ||||.||||..||   ||. || ||||. |  ..|.||||  .|||||||||||.|.|.|||..||.. | . ..||
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVIKEDIYSPKEGAKFPIKWTAPEAALYSRFTIKSDVWSFGVLVAEVVTKGAMPYPG
| |.| ||| ||..  ..||||||||.|||.|| ||.|||||||....|.|  |.|||.|||||||||||| ||||||||||||.|. |.|| | .||||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPG

MTNRQVLESVEAGYRMPKPDTCPDPLYSI-MMECWRHEPDDRPTFESLKYRL
|.||.||. |. ||||||.. ||| || . || ||  .|  ||||| |   .
MMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK409.AA SrcB 250-501 57 7.4e-134 451.0 In-house 1-251 (251) Show / Hide 
Range on Protein: 250-501
Range on HMM: 1-251/251
Sequence Identity: 57% (145 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGTMEVNDFVKEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHGSLLDYLRNGKGRYVNVHQMID
|.. |||| | ||||| | .|. . ||.||.|.||| .. |..|| |||.. | .| .|||| | | ||||.|| | .|.|||.|.  .|  ... ..||
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVIKEDIYSPKEGAKFPIKWTAPEAALYSRFTIKSDVWSFGVLVAEVVTKGAMPYPG
| |||. ||||.|.. |||||| | |||| |  .||.|||||||.| .. |  .||||||||||||||  .  |||||||||||.|. |.|| | .||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

MTNRQVLESVEAGYRMPKPDTCPDPLYSIMMECWRHEPDDRPTFESLKYRLD
||| .|....| |||||.||.||. || |||.||.. |..||||. |.  ||
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK409.AA SRM 250-501 50 6.7e-132 443.59 In-house 1-253 (253) Show / Hide 
Range on Protein: 250-501
Range on HMM: 1-253/253
Sequence Identity: 50% (127 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGT-MEVNDFVKEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHGSLLDYLRNGKGRYVNVHQMI
  . .|||.| ||||| |||    .||||  |    |   .. || | |||  | |.. |.|||.. .|.||.||||  |.|. |||   ..   . ...
FTLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLL

DMIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVIKEDIYSPKEGAKFPIKWTAPEAALYSRFTIKSDVWSFGVLVAEVVTKGAMPYP
|.  |.  ||.||||  ||||||||||.|||..| |||.|||||| ||.|||||  . . |.|||||||| |  . .||||||||.|  |. |.| .|||
DFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYP

GMTNRQVLESVEAGYRMPKPDTCPDPLYSIMMECWRHEPDDRPTFESLKYRLD
||||   .  ...||||| |  ||   .  |.|||. .|..||.|  |  .| 
GMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase AqueK409.AA TK 250-500 26 3.2e-123 415.18 In-house 1-486 (486) Show / Hide 
Range on Protein: 250-500
Range on HMM: 1-486/486
Sequence Identity: 26% (131 aa)

LQFNKKLGQGNFG---EVWSGLWNET--------------------------TPVAIKTLKPG-TMEVNDFVK--------------EAQVMKKIH----
... ||||.|.||   ||. |.|..                           ||||.|.||.| .|. ..|                ||..||. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPHLLQLYAVCTLE------------EPIYIVTELMSHGS----LLDYLR--NGKGRY-----------------------------------------
 ||....||.||| .            ||..||.|.|.||.    |.||||   .|..                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VNVHQMIDMIAQISSGMAYLEEH------SYIHRDLAARNILVGEGNS-----------CKVADFG---
                               ...||.. | .||..||.||...       ..||||||||.||||.|            ||.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARVI-KEDIYSPKE------------------------GAKFPIKWTAPEAAL---------YSRFTIKSDVWSFGVLVAEVVTKGAMPYPG-M
     ||| | ..| |  |.                        |.|.||.|.|||. .         | .||.||||||||||. |..| |..||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------RQVLESVEAG--------------YRMPKPDTCP--------------DPLYSIMMECWRHEPDDRPTFESLKYRL
.|         ..|.| ...|              .|||.|. ||              . .| .|..||...|.|||||. |. .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK409.AA Tec 250-502 48 5.3e-117 395.0 In-house 1-254 (254) Show / Hide 
Range on Protein: 250-502
Range on HMM: 1-254/254
Sequence Identity: 48% (123 aa)

LQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGTMEVNDFVKEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHGSLLDYLRNGKGRYVNVH-QMI
| | | ||.| || |  | |     ||||..| |.|   ||. ||.||.|  || | ||| ||. . ||||||| |.||.||.|||  |..        .
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

DMIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVIKEDIYSPKEGAKFPIKWTAPEAALYSRFTIKSDVWSFGVLVAEVVTKGAMPYP
.|  ... ||||||.|..||||||||| |||. .  ||.|||..| .  | |    |.|||.|| .||   |||.  |||||.||||  || . | |||.
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE

GMTNRQVLESVEAGYRMPKPDTCPDPLYSIMMECWRHEPDDRPTFESLKYRLDD
 |.| .| | |  |.|. .|. |.. .| || .||...|..||||. |   . .
NMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK409.AA S_TKc 250-504 24 1.6e-54 188.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 250-504
Range on HMM: 1-231/231
Sequence Identity: 24% (65 aa)

LQFNKKLGQGNFGEVWSGLWNE-TTPVAIKTLKPGTMEVNDFVKEAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSH--GSLLDYLRNGKG----RYV
 .. .|.|.| ||.|. . ...    |||| .|      ... .| |..|| |||.. .|| |.   . .|.|.|....  |.|.||... ..    .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NVHQMIDMIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSCKVADFGLARVIKEDIYSPKEGAKFPIKWTAPEAALYSRFTI-KSDVWSFGVLVAEVVT
.  .   ...|| ....|. .|  |||||   |||. |    |..||||||..                . |||      ..  |.|.||.|....| ..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KGAMPYPGMTNRQVLESVEAGYRMPKPDTCPDPLYSIMMECWRHEPDDRPTFESLKY-----RLDDYY
 |  |.|  .  .... .            .... .... |.. .|..|||   .       ... . 
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK409.AA Pkinase 250-500 22 1.7e-43 154.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 250-500
Range on HMM: 1-293/293
Sequence Identity: 22% (67 aa)

LQFNKKLGQGNFGEVWSGLWNET-TPVAIKTLKPGTMEVNDFVK-----EAQVMKKIHHPHLLQLYAVCTLEEPIYIVTELMSHG----SLLDYLRNGKG
... .|.|.|.||.|. . .  |   ||.|..|  . . .  .      |.|.||...||. ..|| ... .  ||.|.|.. .|    .| ||..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RYV--NVHQMIDMIAQISSGMAYLEEHSYIHRDLAARNILVGEGNSC----KVADFGLARVIKEDIYSPKEGAKFP---IKWTAPEAAL-YSRFTIKSDV
. .    .. .... || .|..|. ... |||||   |||. . . .    |..|||||....   | ... .. .   . . |||  . ..  . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGVLVAEVVTKGAMPYPGM----TNRQVLESVEAGYRMPKPDTCP-----------------------DPLYSIMMECWRHEPDDRPTFESLKYR--L
||.|....|... |  |.||     . .  .. ..   . | .  .|                       ... ...  |..  | .|||.| ..    .
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF