Gene AqueK408 (A.queenslandica)

AqueK408

Species: A.queenslandica
Alias: AqueK408
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Frk

Sequence

Name Sequence Type Origin Length Description Download
AqueK408.AA Protein None 514 None Fasta, JSON
AqueK408.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of AqueK408.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 AqueK408.AA SH3 67-124 43 2.6e-24 88.02 SMART 1-58 (58) Show / Hide 
Range on Protein: 67-124
Range on HMM: 1-58/58
Sequence Identity: 43% (25 aa)

PVYVGKYDYDSRTDDDLSFKKGNLLYIISTDEGDWWFARSKDTGKEGYIPSNYVAEYK
|... .|||.....|.||||||  ..... |...|| .| ..||.||..|||||.|..
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK408.AA SH3_1 70-117 44 1.2e-22 79.18 Pfam 1-49 (49) Show / Hide 
Range on Protein: 70-117
Range on HMM: 1-49/49
Sequence Identity: 44% (22 aa)

VGKYDYDSRTDDDLSFKKGNLLYIISTDEG-DWWFARSKDTGKEGYIPS
| .|||. ...|.||||||  ...|. ... |||..|...||.||..||
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 AqueK408.AA SH3_2 68-123 26 1.1e-12 47.27 Pfam 1-68 (68) Show / Hide 
Range on Protein: 68-123
Range on HMM: 1-68/68
Sequence Identity: 26% (18 aa)

VYVGKYDYDS-RTDDD-----LSFKKGNLLYII---STDEGDWWFA-RSKDTGKE--GYIPSNYVAEY
.|.   ||.. .  ..     |.|||| ....|   ..| ..||.. .....|..  |..||..|.|.
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK408.AA SH2 131-208 49 5.7e-41 122.11 Pfam 1-81 (81) Show / Hide 
Range on Protein: 131-208
Range on HMM: 1-81/81
Sequence Identity: 49% (40 aa)

WYFGKLKRNEAEKQLMMPYNDYASYLVRDSETTPGDFSLSVRDTN---RVRHYKIRRLDDGSFFVTRRVQFATIPELIMFY
||.||. |.|||..|| | |   ..|||.||.||||..||||| .   ||.||.|.|.|.| ...| |..|....||...|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK408.AA SH2 129-214 43 1.4e-32 115.46 SMART 1-87 (87) Show / Hide 
Range on Protein: 129-214
Range on HMM: 1-87/87
Sequence Identity: 43% (38 aa)

EEWYFGKLKRNEAEKQLMMPYNDYASYLVRDSETTPGDFSLSVRDTNRVRHYKIRRLDDGSFFVTR--RVQFATIPELIMFYQRQADG
..||.|.. | |||. |. | .   ..||||||..|||..||||. ..|.||.|||.|||.....   |..| .. ||. .||. ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK408.AA SFK-Src 249-502 64 7.6e-210 628.87 In-house 1-259 (259) Show / Hide 
Range on Protein: 249-502
Range on HMM: 1-259/259
Sequence Identity: 64% (167 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGTMSPQEFLQEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHGSLLDYLRA-DGRSLQQAQLID
..| ..||.||||.|| | ||.||.||||||| |.|| .||||||..||.||||.|||||||||   ||.||||||| |||||||.   ||||.  ||.|
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVI-DEDI-YEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPY
| ||||.|||||| ||..||||||||.|||.  .|||.|||..||. ..|. |.||.|||||||||||||. .||| || ||||||| ..|..|||| ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMTNAEVLEKLPQ--GYRMGCPTSCPKELHDVMLECWREDPSNRPTFESLQWRLEEFY
|||||.||| .. .  |||| ||. || |.. .|..||.. |..|||||||.|..|.|.
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK408.AA Src 249-498 68 3.2e-187 628.26 In-house 1-255 (255) Show / Hide 
Range on Protein: 249-498
Range on HMM: 1-255/255
Sequence Identity: 68% (175 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGTMSPQEFLQEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHGSLLDYLR--ADGRSLQQAQLI
.||.|.||.|||||||.|.|||.|.||||||| |||||. ||||| .|| |||.||.||||||.. .||.|.||.|.||||||||.   .||.|.  |||
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVID--EDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFP
|| ||||.||||||..|||||||||||.||||...||||||||||.|.  .|.|.|..|||||||||||||. |.|||||.||||||| |.|..|||| |
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMTNAEVLEKLPQGYRMGCPTSCPKELHD-VMLECWREDPSNRPTFESLQWRL
||||||.|||... .|||| ||. ||.||.. .||.||..||  ||||| ||| |
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK408.AA Frk 249-502 69 4.4e-166 558.05 In-house 1-260 (260) Show / Hide 
Range on Protein: 249-502
Range on HMM: 1-260/260
Sequence Identity: 69% (180 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGTMSPQEFLQEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHGSLLDYLR---ADGRSLQQAQL
..|.||||.|||||||||||| || |||||||.||| |..||.|| .||.|||||||||||||| ..||.||||||.||||..||.     ||..|  ||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

IDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLAR-VIDEDI--YEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGR
.|| |||||||||||.||||||||||||.|||||.|||.||||||| .. ...  ||...||.||||||||||| ||.||||.|||||||.|.|.|||||
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

FPYPGMTNAEVLEKLPQGYRMGCPTSCPKELHDVMLECWREDPSNRPTFESLQWRLEEFY
 |||||||||||. . .|||| .|. ||..| ..|||||..|| .||||| |||.||...
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK408.AA Pkinase_Tyr 249-498 47 7.29999999999e-156 528.49 Pfam 1-270 (270) Show / Hide 
Range on Protein: 249-498
Range on HMM: 1-270/270
Sequence Identity: 47% (129 aa)

VKLLRRLGAGQFGEVWEGLWN-----GTTQVAVKTLKTGTMSP----QEFLQEAALMKRL-RHPKLIQLYAVCT-KQDP--IFIITELMKHGSLLDYLRA
..... ||.|.||||..| |.     ....||||.|| |.|..    ..|..||..|| | .||....||.||| ...|  |.|..|.|.||.||||||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

D---GRSLQQAQLIDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVI-DEDIY-EAHTGAKFPIKWTAPEAAMYNRFTIKADVWSF
    ...|   .|..||.|.|.||.|||..|.|||||||||.||.| ...|..|||||| | ..| |  ...|.|.||||.|||. .|..||.| |||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GIVLYEVITYGRFP-YPGMTNAEVLEKL-PQGYRMGCPTSCPKELHDVMLECWREDPSNRPTFESLQWRL
|....|..|||. | ||||.|.||.|..  .|||| ||  ||.|..|.|..||..||..||||. ....|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK408.AA SrcA 249-498 65 8.8e-156 496.07 In-house 1-250 (250) Show / Hide 
Range on Protein: 249-498
Range on HMM: 1-250/250
Sequence Identity: 65% (164 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGTMSPQEFLQEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHGSLLDYLR-ADGRSLQQAQLID
..| |||| |.||||| | |||||.||.|||| |||||. ||.|| .||.||| ||.|||||    .||.|.|| | .|||||.|.  .|. |.  ||.|
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYPG
| ||||.||||.|  ||||||| | ||||||.||||.|||||||.|... |.|. ||||||||||||||.| |||||.|||||||.| |..| || ||||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG

MTNAEVLEKLPQGYRMGCPTSCPKELHDVMLECWREDPSNRPTFESLQWRL
| | ||||.  .||.| ||  ||. ||..| .||| ||  ||||| ||  |
MNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK408.AA Src-Unclassified 249-498 47 6.6e-144 484.38 In-house 1-284 (284) Show / Hide 
Range on Protein: 249-498
Range on HMM: 1-284/284
Sequence Identity: 47% (136 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTG---TMSPQEFL--------QEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHGSLLDYLRADG
|.||| || ||||||| | | |   |||||.. |   ||||  ||        |||..|| .||..|..|||||..  |..||||.|  ||||..|| .|
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

-RSLQQAQL------------IDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHL-----ICKVADFGLA--RVIDEDIYEAHTGAKFPIKWTAPEAAM
 . |    .            .|. |||| || |||   |.||||||||.|.|.       . ||.|||||  ... .|.|.. |||.||.||.|||.. 
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YNRFTIKADVWSFGIVLYEVITYGRFPYPGMTNAEVLEKLPQGYRMGCP--TSCPKELHD-VMLECWREDPSNRPTFESLQWRL
|  |.|| ||||.|| |.|. |.|. ||||| | |||| .  ||||  |    ||  . . .|. || .||  ||||. |   .
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK408.AA SrcB 249-499 61 1.6e-142 479.82 In-house 1-251 (251) Show / Hide 
Range on Protein: 249-499
Range on HMM: 1-251/251
Sequence Identity: 61% (154 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGTMSPQEFLQEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHGSLLDYLRAD-GRSLQQAQLID
.|| ..|||||||||| | .|. ..|||||.| |||||. ||.|| .|| | | .|..|||| ||  ||.|||| |..|.|||.|..| |  |.  .|||
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYPG
| ||.| ||||.|..||||||| | |||| | |.||.|||||||.|... | |. |||||||||||||  .  ||||.|||||||.|.|..|||| ||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

MTNAEVLEKLPQGYRMGCPTSCPKELHDVMLECWREDPSNRPTFESLQWRLE
|||.||.. | .|||| .|  ||.|| ..| .||.| | .||||. ||  |.
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK408.AA TyrKc 249-498 43 4e-142 479.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 249-498
Range on HMM: 1-280/280
Sequence Identity: 43% (123 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGTMSPQEFLQEAALMKRL--RHPKLIQLYAVCTKQ-------DPIFIITELMKHGSLLDYLRADGRS
..|.. || |.||||..| |.  .|||||.|| ..   ..|..|| .|..|  .|| ...||.|||.|       .|..|..|.|.||.|.||||. .. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LQQAQLIDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDED--------IYEAHT--GAK--FPIKWTAPEAAMYNRFTIKADV
|. ..|...| |.|.||.||...|.|||||||||.|||| ...|..||||.| |..|         | . .  |.|  .||.|.|||. .|..||.| ||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGIVLYEVITYGRFPYPG-----MTNAEVLEKLPQGYRMGCPTS--------CPKELHDVMLECWREDPSNRPTFESLQWRL
||||....|. |||  ||||     |.|.||.|.. ||||| .| .        ||.|....|..||.|||..||||. .  ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK408.AA SRM 250-499 54 3.2e-132 444.69 In-house 2-253 (253) Show / Hide 
Range on Protein: 250-499
Range on HMM: 2-253/253
Sequence Identity: 54% (137 aa)

KLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGT-MSPQEFLQEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHGSLLDYLR-ADGRSLQQAQLID
 | |.||.| ||||||||| |  .||.|  |    |  ... .|   || ||| ..| |.|||.  ||..||||||. |.|. |||  |.. |.  .|.|
TLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLD

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYPG
.  ||| ||.||| ||||||||||||.|||. ..|||.|||||| | .|||    . . |.|||||||| |  . .| ||||||| |.|. |||  ||||
FACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPG

MTNAEVLEKLPQGYRMGCPTSCPKELHDVMLECWREDPSNRPTFESLQWRLE
||| | . .   |||| ||  || | |  |||||. ||  ||.|  |  .| 
MTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase AqueK408.AA Src-Echino1 249-498 54 1.2e-127 430.34 In-house 1-252 (252) Show / Hide 
Range on Protein: 249-498
Range on HMM: 1-252/252
Sequence Identity: 54% (137 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGTMSPQEFLQEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHGSLLDYLRAD-GRSLQQAQLID
... ...| |..||||.|.||| |.||||||| .|||| .|| || .||..||  ..|.||||  ..||.|.||||..|.|.|||. . .. .. ..|||
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYPG
| |..|.|| ||...|..||||||||.|||.  .||.|||||||....|.| .. |||.||||||||||.| |||||.|||||||.. |..|.||.||||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPG

MTNAEVLEKLPQGYRMGCPTSCPKELHDV-MLECWREDPSNRPTFESLQWRL
|.| |||... .||||  .  ||  |... |. ||  ||  ||||| |   .
MMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK408.AA TK 249-498 26 1.7e-126 426.32 In-house 1-486 (486) Show / Hide 
Range on Protein: 249-498
Range on HMM: 1-486/486
Sequence Identity: 26% (131 aa)

VKLLRRLGAGQFG---EVWEGLWNGT--------------------------TQVAVKTLKTG-TMSPQE--------------FLQEAALMKRLR----
..|.. ||.||||   ||..|.|.|                           |.||||.|| | .||..|              ||.||. || ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPKLIQLYAVCTKQ------------DPIFIITELMKHGS----LLDYLRADGR---------------------------------------------
 || ...||.|||..             |. |..|.|.||.    |.||||.  .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------SLQQAQLID-------------------MCAQVAAGMAYLEQQ------NYIHRDLAARNILVGEHLI-----------CKVADFG----
          .|....|..                   ||.|.|.||.||...      |..||||||||.||||...           ||.||||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LARVIDED-IYEAHT------------------------GAKFPIKWTAPEAAM---------YNRFTIKADVWSFGIVLYEVITYG-RFPYPGMT
    ||| |..|  | ...                        |.|.||.|.|||. .         |..||.| ||||||....|. |||   .|.||.
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------AEVLEKLPQG--------------YRMGCPTSCP--------------KELHDVMLECWREDPSNRPTFESLQWRL
|         .||.|.| .|              .|| .|  ||              .|..|.|..||..||. ||||. |. .|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK408.AA Tec 249-500 46 2e-124 419.67 In-house 1-254 (254) Show / Hide 
Range on Protein: 249-500
Range on HMM: 1-254/254
Sequence Identity: 46% (117 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGTMSPQEFLQEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHGSLLDYLRADGRSLQQAQ--LI
 .... || |||| |  | | .  .||.|..| |.||  .|..||  |. | ||||.||| ||..| ||.|.|| |.||.||.|||  .  .|...  |.
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

DMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTIKADVWSFGIVLYEVITYGRFPYP
.|| .|  ||||||....||||||||| |||.  . ||.|||..| .  | |   .|.|||.|| .||  .|.|.  | |||.||.   || . |. ||.
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE

GMTNAEVLEKLPQGYRMGCPTSCPKELHDVMLECWREDPSNRPTFESLQWRLEE
 |.| || |.  ||.|.  | .|.... ..| .||.| |  ||||. |   ..|
NMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK408.AA S_TKc 249-502 26 2.5e-56 194.34 SMART 1-231 (231) Show / Hide 
Range on Protein: 249-502
Range on HMM: 1-231/231
Sequence Identity: 26% (71 aa)

VKLLRRLGAGQFGEVWEGLWNG-TTQVAVKTLKTGTMSPQEFLQEAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKH--GSLLDYLRADGRS-----L
 ..|| .| | ||.|. . ...   .||.| .|      . ...| ...|. .|| ...|| |.   | .....|.. .  |.|.||..  ||      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

QQAQLIDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLICKVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAMYNRFTI-KADVWSFGIVLYEVIT
   .   ...|.. ...|. ... |||||   |||. |    |..||||||..        |       . |||      ..  |.|.||.|..||| ..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

YGRFPYPGMTNAEVLEKLPQGYRMGCPTSCPKELHDVMLECWREDPSNRPTFESLQ----WRLEEFY
 |. |.|  . .....|.            ..|. | .  |.. ||..||| | ||    ... .. 
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase AqueK408.AA Pkinase 249-494 25 7.2e-51 180.12 Pfam 1-287 (293) Show / Hide 
Range on Protein: 249-494
Range on HMM: 1-287/293
Sequence Identity: 25% (74 aa)

VKLLRRLGAGQFGEVWEGLWNGTTQ-VAVKTLKTGTMSPQEFLQ-----EAALMKRLRHPKLIQLYAVCTKQDPIFIITELMKHG----SLLDYLR-ADG
 ...|..|.| ||.|... . || . ||||..|  . ....  .     |...||||.||  ..|| ...  | | ...|.. .|    .| ||..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RSL--QQAQLIDMCAQVAAGMAYLEQQNYIHRDLAARNILVGEHLIC----KVADFGLARVIDEDIYEAHTGAKFPIKWTAPEAAM-YNRFTIKADVWSF
...  .  ...... |.. |..|. ... |||||   |||. ..  .    |..|||||...|.  ..  |.    . . |||  . ..  . |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIVLYEVITYGRFPYPGM----TNAEVLEKLPQGYRMGCPTSCP-----------------------KELHDVMLECWREDPSNRPTFESL
|..|||... ||.|.||     . .. .... .  .   . ..|                       .|. |..  |.. ||. |||.| .
GCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI