Gene AqueK403 (A.queenslandica)
AqueK403
Species: A.queenslandica
Alias: AqueK403
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK403.AA | Protein | None | 1089 | None | Fasta, JSON |
| AqueK403.kin_dom | Protein Kinase Domain | None | 49 | None | Fasta, JSON |
Protein domains of AqueK403.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK403.AA | Ryk | 964-1030 | 58 | 4.5e-37 | 114.61 | In-house | 201-267 (292) | Show / Hide |
Range on Protein: 964-1030 Range on HMM: 201-267/292 Sequence Identity: 58% (39 aa) PVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDL |||||. | | | ||. |||||||| .|| || |..||... |. | .|| | ||.|| |||| | PVKWMSLESLQHKHYSHASDVWSFGVTMWELMTLGQMPYMEIDPFEMYHYLKDGYRLQQPFNCPDEL |
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| Pkinase_Tyr | AqueK403.AA | Pkinase_Tyr | 964-1033 | 45 | 9.4e-36 | 121.71 | Pfam | 177-248 (270) | Show / Hide |
Range on Protein: 964-1033 Range on HMM: 177-248/270 Sequence Identity: 45% (33 aa) PVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTP-YEDVLPENMLNYL-TTGHRLPQPKNCPDDLRDL |.|||| |......... ||||||||..|||.|.|..| |... .| ...|. |.|.|.|.||||.. || PIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDL |
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| Kinase | AqueK403.AA | Met | 964-1030 | 48 | 3.9e-33 | 105.76 | In-house | 173-251 (271) | Show / Hide |
Range on Protein: 964-1030 Range on HMM: 173-251/271 Sequence Identity: 48% (38 aa) PVKWMAAEVLS--------DKR-YSSSSDVWSFGVVLWEIMTRGKTPYEDVLP-ENMLNYLTTG--HRLPQPKNCPDDL |||||| | | . | ... |||||||||.|| |||| .|| .| . . .| .| ||||| ||| | PVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEYCPDHL |
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| Kinase | AqueK403.AA | TK | 964-1033 | 27 | 1.1e-30 | 99.51 | In-house | 348-464 (486) | Show / Hide |
Range on Protein: 964-1033
Range on HMM: 348-464/486
Sequence Identity: 27% (32 aa)
PVKWMAAEVLS---------DKRYSSSSDVWSFGVVLWEIMTRGKTPYEDVLP----------ENMLNYLTTG--------------HRLPQPKNCP---
|..||| |.| ...... ||||||||..|||.|.|..|| .. . ...||..| .|.|||..||
PIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWM
-----------DDLRDL
... ||
RYRMHPPHCPPEEYYDL
|
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| Kinase | AqueK403.AA | FGFR | 964-1030 | 50 | 1.2e-30 | 101.58 | In-house | 201-268 (293) | Show / Hide |
Range on Protein: 964-1030 Range on HMM: 201-268/293 Sequence Identity: 50% (34 aa) PVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTPYEDVL-PENMLNYLTTGHRLPQPKNCPDDL |.|||| | | |. | . |||||.|| |||||| | .|| .. | . || .|||. |.||. .. PIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEI |
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| Kinase | AqueK403.AA | TK-Unique | 964-1033 | 39 | 2.4e-29 | 98.38 | In-house | 199-272 (294) | Show / Hide |
Range on Protein: 964-1033 Range on HMM: 199-272/294 Sequence Identity: 39% (29 aa) PVKWMAAEVLS--DKRY-SSSSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNC-PDDLRDL |..||| |.|. .. | .. ||||||||..|||.| |..|| .. ...... .. |.|.|||..| ..... | PIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNL |
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| Kinase | AqueK403.AA | Axl | 964-1033 | 60 | 1.8e-28 | 97.81 | In-house | 178-247 (267) | Show / Hide |
Range on Protein: 964-1033 Range on HMM: 178-247/267 Sequence Identity: 60% (42 aa) PVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLRDL ||||.| | | |. | | ||||.||| .|||||||.||| | . | .|| |||| ||..| |.| || PVKWIAIESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPEDCMDELYDL |
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| Kinase | AqueK403.AA | UTK | 964-1030 | 41 | 4.1e-27 | 89.81 | In-house | 202-271 (296) | Show / Hide |
Range on Protein: 964-1030 Range on HMM: 202-271/296 Sequence Identity: 41% (29 aa) PVKWMAAEVLSDK-RYSSSSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTG--HRLPQPKNCPDDL |..||| |.| . |....|||||||||.|||.|.|..||.. .. . .. | .|.|.|. ||... PIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPV |
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| Kinase | AqueK403.AA | Fer | 964-1033 | 31 | 7.2e-26 | 85.17 | In-house | 181-259 (283) | Show / Hide |
Range on Protein: 964-1033 Range on HMM: 181-259/283 Sequence Identity: 31% (25 aa) PVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTPYED----VLPENM-----LNYLTTGHRLPQPKNCPDDLRDL |..|.| |..... ||. .|||||||..|||.|.|..||.. . . |. .. . |...| |...|.... . PIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQI |
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| Kinase | AqueK403.AA | EGFR | 964-1030 | 44 | 1.2e-25 | 82.0 | In-house | 166-232 (258) | Show / Hide |
Range on Protein: 964-1030 Range on HMM: 166-232/258 Sequence Identity: 44% (30 aa) PVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDL |.|||| |... ..| . |||||.|| .||.|| |. ||. . .. . | | |||||..| |. PIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFGQKPYDGIPAREIPDLLEKGERLPQPPICTIDV |
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| Kinase | AqueK403.AA | RTKB | 964-1033 | 42 | 1.2e-24 | 80.03 | In-house | 172-242 (264) | Show / Hide |
Range on Protein: 964-1033 Range on HMM: 172-242/264 Sequence Identity: 42% (30 aa) PVKWMAAEVLSDKRYSSSS-DVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLRDL |.|||| | . ...|.. | ||||||| ||| . | ||| ....| |||||.|. | ... PIKWMAPESWAHRIYTTKSGDVWSFGVTMWEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHI |
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| TyrKc | AqueK403.AA | TyrKc | 875-1051 | 16 | 1.6e-10 | -52.63 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 875-1051
Range on HMM: 1-280/280
Sequence Identity: 16% (48 aa)
LTNNKTIQE----LVIRYHSISDRGVT------------------NICQAL--EHNSTLTSLDLSYNP------------LITSTSGKALSHLLLNNSS-
.| .|.. | | . . . .. .| | .| . . . . .. .| . | ..
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK
-----------------------------------LVKLNI------------TEDY-------NTIEERGGGGDET-IAYPVKWMAAEVLSDKRYSSSS
||. | .|. .. ....| | . |..||| |.. ...... |
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTML--PIRWMAPECINYGKFTTKS
DVWSFGVVLWEIMTRGKTPYED-----VLPENMLNYLTTGHRLPQPKN--------CPDDLRDL-------SPSQRSDRSILFREKDKL
|||||||..|||.|.|..||.. . .. ...|. .|.|.|||.| |||.. .. |..| | . ....
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
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| Kinase | AqueK403.AA | Pkinase | 967-1011 | 26 | 5.3e-09 | 32.91 | Pfam | 177-224 (293) | Show / Hide |
Range on Protein: 967-1011 Range on HMM: 177-224/293 Sequence Identity: 26% (13 aa) WMAAEVLS-DKRYSSSSDVWSFGVVLWEIMTRGKTPYEDV----LPENML .|| ||. .. |....|.||.|..|.| .. |..|. . ... YMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQM |
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| S_TKc | AqueK403.AA | S_TKc | 826-1052 | 11 | 7e-06 | -90.6 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 826-1052
Range on HMM: 1-231/231
Sequence Identity: 11% (31 aa)
HKVVELDSSSTNSTVSLLSSNK-LHTVNLRSLEIRATPLTNDCIQYLCILLTNNKTIQELVIRYHSISDRGVTNICQALEHNST----LTSLDLSYNP--
..... . . ..| . .| . | . . .. .. . || . ..... . . .... .|. .. | .. ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----------LITSTSGKALSHL---------------LLNNSSLVKL------NITEDYNTIEERGGGGDETIAYPVKWMAAEVLSDKRYSS-SSDVWS
.. .|| .. ||.. .|. . |. .|| ||| |. ..|.||
LRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWS
FGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLRDL-------SPSQRSDRSILFREK-----DKLV
.|..|.| .. |..|.. .. |.. . .....|. |..| .... . .
CGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| LRR_RI | AqueK403.AA | LRR_RI | 878-905 | 28 | 0.003788 | 15.63 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 878-905 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NKTIQELVIRYHSISDRGVTNICQALEH |....|| ... . | |. .|..|.| NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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| LRR_RI | AqueK403.AA | LRR_RI | 906-934 | 31 | 0.013609 | 11.71 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 906-934 Range on HMM: 1-28/28 Sequence Identity: 31% (9 aa) NSTLTSLDLSYNPLITSTSGKALSHLLLN |..| |.||.|.| . ...|...| NCSLRELWLSNNKL-GDEGCRQLCEGLKH |
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| LRR_RI | AqueK403.AA | LRR_RI | 850-877 | 25 | 0.443561 | 1.03 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 850-877 Range on HMM: 1-28/28 Sequence Identity: 25% (7 aa) TVNLRSLEIRATPLTNDCIQYLCILLTN . .|| | .. .|. . .. || .|. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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