Gene AqueK402 (A.queenslandica)

AqueK402

Species: A.queenslandica
Alias: AqueK402
External Links:
Annotation:

Classification

Group: TK
Family: Ret

Sequence

Name Sequence Type Origin Length Description Download
AqueK402.AA Protein None 126 None Fasta, JSON
AqueK402.kin_dom Protein Kinase Domain None 91 None Fasta, JSON

Protein domain

Protein domains of AqueK402.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK402.AA Pkinase_Tyr 5-100 47 1.9e-46 157.96 Pfam 175-270 (270) Show / Hide 
Range on Protein: 5-100
Range on HMM: 175-270/270
Sequence Identity: 47% (47 aa)

KLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLSRVP-YPGLDPVGVVELL-DTGGRLHTPNNEACSKEIYSLMMSCWSESPDDRPVFSDLVSSI
||| ||||.|.|..| |..||||||.|||.||.|.. . | |||...  |.|.. . |.|.  | |  |..|||.||..|| . |.||| ||.... .
KLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK402.AA KIN6 5-100 46 2.6e-43 140.87 In-house 210-305 (305) Show / Hide 
Range on Protein: 5-100
Range on HMM: 210-305/305
Sequence Identity: 46% (46 aa)

K-LPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLSRVPYPGLD-PVGVVELLDTGGRLHTPNNEACSKEIYSLMMSCWSESPDDRPVFSDLVSSI
. ||.||||.|..    || ||||||.||| .|.|||  ||||..  |. . | .  |.|.  | .  |..|||  |.|||.| ||||| |...   .
RYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW--CPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase AqueK402.AA TK 5-100 31 3.7e-41 135.22 In-house 346-486 (486) Show / Hide 
Range on Protein: 5-100
Range on HMM: 346-486/486
Sequence Identity: 31% (45 aa)

KLPLKWMALESIHDGL---------FSEKSDVWSYGVLCWEVFSLSRVPYPGLDPV----------GVVELLDTGGR------------LHTPNNEACS-
|||..||| |.. |.          |..||||||.|||.||.|.. ..||.|  .            |.|.| .|||            .  |  . |. 
KLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPD

-------------KEIYSLMMSCWSESPDDRPVFSDLVSSI
             .|.| ||..||.. |.||| ||.|.. .
WMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK402.AA UTK 1-100 39 1.7e-38 129.3 In-house 196-296 (296) Show / Hide 
Range on Protein: 1-100
Range on HMM: 196-296/296
Sequence Identity: 39% (40 aa)

SPTVKLPLKWMALESIHDG-LFSEKSDVWSYGVLCWEVFSLSRVPYPGLDPVGVVELLDTGGRLHTPNNEACSKEIYSLMMSCWSESPDDRPVFSDLVSS
..  ..|..||| |.. ..  |..||||||.||.|||...  |.||||.  . |.. .  |||.. | ...|. ..| ||..||  .|..|| | |||. 
QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQ

I
.
M
Kinase AqueK402.AA TK-Unique 5-100 41 1.2e-36 123.95 In-house 197-294 (294) Show / Hide 
Range on Protein: 5-100
Range on HMM: 197-294/294
Sequence Identity: 41% (41 aa)

KLPLKWMALESIH--DGLF-SEKSDVWSYGVLCWEVFSLSRVPYPGLDPVGVVELLDTGGRLHTPNNEAC-SKEIYSLMMSCWSESPDDRPVFSDLVSSI
..|..|||.||.   .| . ..||||||.||| ||.|.|   ||||...  ..|..  | |.  |..  | |.|.|.|| |||...|..|| |..... .
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK402.AA ALK 6-102 45 2.4e-36 122.94 In-house 179-273 (273) Show / Hide 
Range on Protein: 6-102
Range on HMM: 179-273/273
Sequence Identity: 45% (44 aa)

LPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLSRVPYPGLDPVGVVELLDTGGRLHTPNNEACSKEIYSLMMSCWSESPDDRPVFSDLVSSINA
.| |||  |   ||.|  |.||||.||||||.||| ..||||     | |.. .|||.  | |  |   .| .|  ||   | ||| | ... .| .
MPVKWMPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase AqueK402.AA VEGFR 5-100 46 4.8e-36 126.08 In-house 238-332 (332) Show / Hide 
Range on Protein: 5-100
Range on HMM: 238-332/332
Sequence Identity: 46% (45 aa)

KLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLSRVPYPGLD-PVGVVELLDTGGRLHTPNNEACSKEIYSLMMSCWSESPDDRPVFSDLVSSI
.||.||||.||| |  .. .||||||||. ||.|||  .|||| .        |  | |. .|  . |  |||  | .||.. |  || ||.||   
RLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAP--DYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase AqueK402.AA Ack 1-100 35 5.1e-35 115.57 In-house 166-266 (266) Show / Hide 
Range on Protein: 1-100
Range on HMM: 166-266/266
Sequence Identity: 35% (37 aa)

SPTV--KLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLSRVPYPGLDPVGVVELLD-TGGRLHTPNNEACSKEIYSLMMSCWSESPDDRPVFSDLV
....  |.|. |.| |..  . || .||||..||  ||.||  . |. |. .  . ...|  | ||. |  ..|...||..|| || . | ||| ||...
EFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRP--DCCPEDIYQMMMQCWQHHPADRPTFSAIR

SSI
   
DQL
Kinase AqueK402.AA Ret 5-102 45 9.3e-35 116.11 In-house 198-293 (293) Show / Hide 
Range on Protein: 5-102
Range on HMM: 198-293/293
Sequence Identity: 45% (45 aa)

KLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLSRVPYPGLDPVGVVELLDTGGRLHTPNNEACSKEIYSLMMSCWSESPDDRPVFSDLVSSINA
..| |||| ||  |  .  ||||||.||||||.  .   ||||  |    .|| || |   | |  || |.|..|  || . || |||| .. . .  
RIPVKWMAIESLYDHVYTTKSDVWSFGVLCWEIVTMGANPYPGIPPERLWQLLKTGYRMDRPEN--CSEEMYRIMRQCWKQEPDKRPVFKFISKDFEK
Kinase AqueK402.AA FGFR 6-100 42 3.9e-34 113.72 In-house 200-293 (293) Show / Hide 
Range on Protein: 6-100
Range on HMM: 200-293/293
Sequence Identity: 42% (41 aa)

LPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLSRVPYPGLD-PVGVVELLDTGGRLHTPNNEACSKEIYSLMMSCWSESPDDRPVFSDLVSSI
|| ||||.|.  |  .  .||||||||| ||.. .   |||.        ..| .| |.  | |  ||.||| .| .|| ..|..|| |  || ..
LPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase AqueK402.AA Tec 5-102 43 1.1e-33 115.04 In-house 159-254 (254) Show / Hide 
Range on Protein: 5-102
Range on HMM: 159-254/254
Sequence Identity: 43% (43 aa)

KLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLSRVPYPGLDPVGVVELLDTGGRLHTPNNEACSKEIYSLMMSCWSESPDDRPVFSDLVSSINA
| | || . |  |   .| |||||..||| |||||. ..||. .. . |||   .| ||. |  . ||..||  | .||.|.|..|| |..| ..|  
KFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRP--HLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK402.AA TyrKc 3-100 15 4.7e-09 -76.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 3-100
Range on HMM: 1-280/280
Sequence Identity: 15% (44 aa)

T---------------------------------------------------------------------------------------------------
                                                                                                    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

----------------------------------------------------------------------VK--LPLKWMALESIHDGLFSEKSDVWSYG
                                                                       |  ||..|||.|.| .| |..||||||.|
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFG

VLCWEVFSLSRVPYPG-----LDPVGVVELLDTGGRLHTPNNEA------CSKEIYSLMMSCWSESPDDRPVFSDLVSSI
|..||.|..   ||||     ...  |.|....|.|.  | |        |..|.|..| .|| | |.||| ||.... .
VCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK402.AA Pkinase 22-100 17 4e-06 22.56 Pfam 190-293 (293) Show / Hide 
Range on Protein: 22-100
Range on HMM: 190-293/293
Sequence Identity: 17% (19 aa)

SEKSDVWSYGVLCWEVFSLSRVPYPGL----DPVGVVELLDTGGR--LHTPNNEACS-------------------KEIYSLMMSCWSESPDDRPVFSDL
. |.|.||.|....|...  | |.||     . .   ....  ..  || .  . ||                   .|  ... .|.   | .|| . ..
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

VSS--I
. .  .
LQHPWF