AqueK401

Species: A.queenslandica
Alias: AqueK401
External Links:
Annotation:

Classification

Group: TK
Family: Ret

Sequence

Name Sequence Type Origin Length Description Download
AqueK401.AA Protein None 118 None Fasta, JSON
AqueK401.kin_dom Protein Kinase Domain None 90 None Fasta, JSON

Protein domain

Protein domains of AqueK401.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK401.AA Pkinase_Tyr 1-90 45 1.7e-42 144.55 Pfam 181-270 (270) Show / Hide
Range on Protein: 1-90
Range on HMM: 181-270/270
Sequence Identity: 45% (42 aa)

MALESLHYGIFSENSDVWSYGVLCWEVFSAGKIP-YSGMDPTGLVELL-DGGQRLSCPDNKACSEDIYSLMQQCWAESPDDRPLFSDLVASV
||.|...||.|.. |||||.|||.||.|. |..| | ||... ..|.. . |.|. ||.|  |...||.||.|||.. |.||| ||...   
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase AqueK401.AA TK 1-90 31 4.6e-37 121.25 In-house 352-486 (486) Show / Hide
Range on Protein: 1-90
Range on HMM: 352-486/486
Sequence Identity: 31% (43 aa)

MALESLH---------YGIFSENSDVWSYGVLCWEVFSAG-KIPYSGMDP---------TGLVELLDGGQR------------LSCPDNKACS-------
|| |.|          ||.|.. |||||.|||.||.|. | . .| ||.          . ..|.|  |.|            . .|  . |.       
MAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM

-------EDIYSLMQQCWAESPDDRPLFSDLVASV
       |..| ||||||.. |.||| ||.|.   
HPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK401.AA KIN6 1-90 46 3.4e-34 110.25 In-house 217-305 (305) Show / Hide
Range on Protein: 1-90
Range on HMM: 217-305/305
Sequence Identity: 46% (42 aa)

MALESLHYGIFSENSDVWSYGVLCWEVFSAGKIPYSGMD-PTGLVELLDGGQRLSCPDNKACSEDIYSLMQQCWAESPDDRPLFSDLVASV
||.|.|    ||  |||||.||| .|.|| |  || .|  || . | . .| |.. |..  |.| ||  ||.||.| ||||| |...    
MAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW--CPEEIYDIMQSCWQEKPDDRPEFNEMRMQF

Kinase AqueK401.AA Syk 4-84 40 1.1e-33 113.35 In-house 179-257 (257) Show / Hide
Range on Protein: 4-84
Range on HMM: 179-257/257
Sequence Identity: 40% (33 aa)

ESLHYGIFSENSDVWSYGVLCWEVFSAGKIPYSGMDPTGLVELLDGGQRLSCPDNKACSEDIYSLMQQCWAESPDDRPLFS
|.  |..||  |||||.||. || || |. || .|    ...... | |..||.   | ...|.||..|| . . ||| |.
ECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNCPN--GCPQEMYQLMNKCWIYKWCDRPTFV

Kinase AqueK401.AA UTK 1-90 39 7.1e-33 109.8 In-house 206-296 (296) Show / Hide
Range on Protein: 1-90
Range on HMM: 206-296/296
Sequence Identity: 39% (36 aa)

MALESLHYG-IFSENSDVWSYGVLCWEVFSAGKIPYSGMDPTGLVELLDGGQRLSCPDNKACSEDIYSLMQQCWAESPDDRPLFSDLVASV
|| |.| ..  |.. |||||.||.|||... |. || ||    ... .  | |.  |....|....| ||..||. .|..|| | |||. .
MAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM

Kinase AqueK401.AA TK-Unique 1-90 39 8.8e-33 110.42 In-house 203-294 (294) Show / Hide
Range on Protein: 1-90
Range on HMM: 203-294/294
Sequence Identity: 39% (37 aa)

MALESLH--YGIF-SENSDVWSYGVLCWEVFSAGKIPYSGMDPTGLVELLDGGQRLSCPDNKAC-SEDIYSLMQQCWAESPDDRPLFSDLVASV
||.|||   .|.. .. |||||.||| ||.|. |. ||.||... ..|..  | |.  |..  | |...|.||..|| ..|..|| |....   
MAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase AqueK401.AA Ack 1-90 42 1.5e-32 107.12 In-house 178-266 (266) Show / Hide
Range on Protein: 1-90
Range on HMM: 178-266/266
Sequence Identity: 42% (39 aa)

MALESLHYGIFSENSDVWSYGVLCWEVFSAGKIPYSGMDPTGLVELLD-GGQRLSCPDNKACSEDIYSLMQQCWAESPDDRPLFSDLVASV
.| |.| .. ||  ||||..||  ||.|| |  |. |. .    ...|  |.||  ||  .|.||||..| |||.. | ||| ||....  
CAPECLRHRQFSHASDVWMFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPD--CCPEDIYQMMMQCWQHHPADRPTFSAIRDQL

Kinase AqueK401.AA Tie 1-90 45 4.3e-32 94.46 In-house 180-267 (267) Show / Hide
Range on Protein: 1-90
Range on HMM: 180-267/267
Sequence Identity: 45% (41 aa)

MALESLHYGIFSENSDVWSYGVLCWEVFSAGKIPYSGMDPTGLVELLDGGQRLSCPDNKACSEDIYSLMQQCWAESPDDRPLFSDLVASV
||.||| | ..  .||||||||| ||. | |  || ||  . | | |  | |.  | |  | ...| ||.||| . | .|| |. .. ..
MAIESLNYSVYTTKSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRN--CDDEVYDLMRQCWRDRPYERPPFAQIAVQL

Kinase AqueK401.AA Ret 1-92 44 2e-30 101.08 In-house 204-293 (293) Show / Hide
Range on Protein: 1-92
Range on HMM: 204-293/293
Sequence Identity: 44% (41 aa)

MALESLHYGIFSENSDVWSYGVLCWEVFSAGKIPYSGMDPTGLVELLDGGQRLSCPDNKACSEDIYSLMQQCWAESPDDRPLFSDLVASVNA
|| |||   ..   |||||.||||||.   | .|| |  |  | .||  | |   |.|  ||| .|..| |||.. || || | ..      
MAIESLYDHVYTTKSDVWSFGVLCWEIVTMGANPYPGIPPERLWQLLKTGYRMDRPEN--CSEEMYRIMRQCWKQEPDKRPVFKFISKDFEK

Kinase AqueK401.AA Tec 4-92 44 4.5e-30 102.29 In-house 168-254 (254) Show / Hide
Range on Protein: 4-92
Range on HMM: 168-254/254
Sequence Identity: 44% (40 aa)

ESLHYGIFSENSDVWSYGVLCWEVFSAGKIPYSGMDPTGLVELLDGGQRLSCPDNKACSEDIYSLMQQCWAESPDDRPLFSDLVASVNA
| .||  .|  ||||..||| ||||| ||.||  |. .  ||    | ||  |  . ||. ||  | .|| |.|..|| |..|  ..  
EVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRP--HLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE

Kinase AqueK401.AA Src 4-90 37 1.7e-29 97.32 In-house 170-255 (255) Show / Hide
Range on Protein: 4-90
Range on HMM: 170-255/255
Sequence Identity: 37% (33 aa)

ESLHYGIFSENSDVWSYGVLCWEVFSAGKIPYSGMDPTGLVELLDGGQRLSCPDNKACSEDIYS-LMQQCWAESPDDRPLFSDLVASV
| ..|| |.  |||||.|.| .|... |..|| ||.    .. .. | |. ||.|  | . .|  .|.||| ..|..|| |  |    
EAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase AqueK401.AA TyrKc 1-90 13 2e-06 -117.23 SMART 1-280 (280) Show / Hide
Range on Protein: 1-90
Range on HMM: 1-280/280
Sequence Identity: 13% (38 aa)

M---------------------------------------------------------------------------------------------------
                                                                                                    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

--------------------------------------------------------------------------------ALESLHYGIFSENSDVWSYG
                                                                                |.|.. ||.|.. |||||.|
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFG

VLCWEVFSAGKIPYSG-----MDPTGLVELLDGGQRLSCPDNKA------CSEDIYSLMQQCWAESPDDRPLFSDLVASV
|..||.|. |. ||.|     |... ..|... | |. .|.|        |....|..|.|||.| |.||| ||...   
VCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK401.AA Pkinase 15-90 15 1.7e-05 20.5 Pfam 193-293 (293) Show / Hide
Range on Protein: 15-90
Range on HMM: 193-293/293
Sequence Identity: 15% (16 aa)

SDVWSYGVLCWEVFSAGKIPYSGM----DPTGLVELLDGGQR--LSCPDNKACS-------------------EDIYSLMQQCWAESPDDRPLFSDLVAS
.|.||.|....|... |. |..|     .     ....   .  |. .  . ||                   |.  ...  |..  | .|| . ... .
VDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

--V
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PWF