Gene AqueK392 (A.queenslandica)
AqueK392
Species: A.queenslandica
Alias: AqueK392
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
AqueK392.AA | Protein | None | 196 | None | Fasta, JSON |
AqueK392.kin_dom | Protein Kinase Domain | None | 85 | None | Fasta, JSON |
Protein domains of AqueK392.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | AqueK392.AA | Pkinase_Tyr | 112-196 | 48 | 1.9e-44 | 151.16 | Pfam | 125-209 (270) | Show / Hide |
Range on Protein: 112-196 Range on HMM: 125-209/270 Sequence Identity: 48% (42 aa) EYLSSIGIIHRDLACRNVLIDADKNLRISDFGMSRKVGGADEAY-VKKTRGRLPWKWMAIESLTEREFSFKSDVWSYGVTLWEIVT |||.|...||||||.||.|.. .. .|.|||..| . |. | .|.. |.|| |||| |.. ...|. ||||||.||..|||.| EYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFT |
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Kinase | AqueK392.AA | TK | 112-196 | 30 | 3.7e-43 | 142.05 | In-house | 248-389 (486) | Show / Hide |
Range on Protein: 112-196 Range on HMM: 248-389/486 Sequence Identity: 30% (43 aa) EYLSSI------GIIHRDLACRNVLIDADKN-----------LRISDFGMSR-------KVGGADEAYVKKT------------------------RGRL |||.| ...|||||.||.|.. ... .|.|||.|| . . |. |..|. .|.| EYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKL PWKWMAIESLTERE---------FSFKSDVWSYGVTLWEIVT | .||| |.|..|. |. ||||||.||..|||.| PIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT |
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Kinase | AqueK392.AA | UTK | 112-196 | 40 | 9.6e-41 | 137.11 | In-house | 132-235 (296) | Show / Hide |
Range on Protein: 112-196 Range on HMM: 132-235/296 Sequence Identity: 40% (42 aa) EYLSSIGIIHRDLACRNVLIDAD-------KNLRISDFG---MSRKVGG--------ADEAYVKKTRGRLPWKWMAIESLTER-EFSFKSDVWSYGVTLW .||.| |..|||||.||.|.... .|.||| ||| |.. .. | . ..|.|..||| |.||.. |..||||||.||..| QYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCW EIVT ||.| EIWT |
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Kinase | AqueK392.AA | FGFR | 112-196 | 56 | 1.8e-36 | 121.76 | In-house | 150-233 (293) | Show / Hide |
Range on Protein: 112-196 Range on HMM: 150-233/293 Sequence Identity: 56% (48 aa) EYLSSIGIIHRDLACRNVLIDADKNLRISDFGMSRKVGGADEAYVKKTRGRLPWKWMAIESLTEREFSFKSDVWSYGVTLWEIVT ||| | .|||||| ||||. | . |.||| .| . | | |.| |||| |||| |.| .| . .|||||||| |||| | EYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCID-YYRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMT |
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Kinase | AqueK392.AA | TK-Unique | 112-196 | 48 | 7.1e-35 | 117.74 | In-house | 145-234 (294) | Show / Hide |
Range on Protein: 112-196 Range on HMM: 145-234/294 Sequence Identity: 48% (44 aa) EYLSS--IGIIHRDLACRNVLIDADKNLRISDFGMSRKVGGADEAYVKK-TRGRLPWKWMAIESLT--EREF-SFKSDVWSYGVTLWEIVT |||.| .|.||||. ||||. ||.. |.||||.|.| ...|... ..||.| .||| ||| .. . . ||||||.||..|||.| EYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT |
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Kinase | AqueK392.AA | Ret | 113-196 | 54 | 1.5e-34 | 115.41 | In-house | 150-232 (293) | Show / Hide |
Range on Protein: 113-196 Range on HMM: 150-232/293 Sequence Identity: 54% (46 aa) YLSSIGIIHRDLACRNVLIDADKNLRISDFGMSRKVGGADEAYVKKTRGRLPWKWMAIESLTEREFSFKSDVWSYGVTLWEIVT |||.. ..||||| ||||. . . ||||| .| | | .|||. ..|.| |||||||| . ||||||.|| .||||| YLSEMKLVHRDLAARNVLVAEGRICKISDFGLTRDVYEDD-SYVKRSKDRIPVKWMAIESLYDHVYTTKSDVWSFGVLCWEIVT |
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Kinase | AqueK392.AA | VEGFR | 112-194 | 51 | 1.8e-34 | 120.85 | In-house | 187-270 (332) | Show / Hide |
Range on Protein: 112-194 Range on HMM: 187-270/332 Sequence Identity: 51% (43 aa) EYLSSIGIIHRDLACRNVLIDADKNLRISDFGMSRKVGGADEAYVKKTR-GRLPWKWMAIESLTEREFSFKSDVWSYGVTLWEI |.|.| .|||||| ||.|.. .. . |.||| .| | ||.|.. |||| ||||.||. .. .. .|||||||| |||| EFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEI |
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Kinase | AqueK392.AA | Fer | 112-194 | 44 | 2.5e-34 | 114.4 | In-house | 125-211 (283) | Show / Hide |
Range on Protein: 112-194 Range on HMM: 125-211/283 Sequence Identity: 44% (39 aa) EYLSSIGIIHRDLACRNVLIDADKNLR---ISDFGMSRKVGGADEAYVKK-TRGRLPWKWMAIESLTEREFSFKSDVWSYGVTLWEI ||| | ..||||.| ||.|...||. ||||||||. . ..| .| . ..| .|.| |... ...|.|.||||.||..||| EYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEI |
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Kinase | AqueK392.AA | Ack | 113-193 | 44 | 5.7e-34 | 111.98 | In-house | 120-203 (266) | Show / Hide |
Range on Protein: 113-193 Range on HMM: 120-203/266 Sequence Identity: 44% (37 aa) YLSSIGIIHRDLACRNVLIDAD-KNLRISDFGMSRKVGGADEAYVKKTRG--RLPWKWMAIESLTEREFSFKSDVWSYGVTLWE || . ..||||||.||.| .| . |.||| .| |... |. . . .| |.| |.|. | || .||||..|||||| YLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGVTLWE |
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Kinase | AqueK392.AA | RTKB | 113-194 | 49 | 4.8e-32 | 105.32 | In-house | 124-203 (264) | Show / Hide |
Range on Protein: 113-194 Range on HMM: 124-203/264 Sequence Identity: 49% (41 aa) YLSSIGIIHRDLACRNVLIDADKNLRISDFGMSRKVGGADEAYVKKTRGRLPWKWMAIESLTEREFSFKS-DVWSYGVTLWEI .|.. ..|||||. ||||.| . .|.||||.|.. |. ...| ||| ||||.||. .| .. || ||||.||| ||| FLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREI---DHECYETTCTRLPIKWMAPESWAHRIYTTKSGDVWSFGVTMWEI |
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Kinase | AqueK392.AA | Src | 112-196 | 43 | 1.2e-31 | 104.78 | In-house | 111-195 (255) | Show / Hide |
Range on Protein: 112-196 Range on HMM: 111-195/255 Sequence Identity: 43% (37 aa) EYLSSIGIIHRDLACRNVLIDADKNLRISDFGMSRKVGGADEAYVKKTRGRLPWKWMAIESLTEREFSFKSDVWSYGVTLWEIVT .||.| .|||||| ||||.. . . ||| | . |. |. .. ..|.||.| | .... |. ||||||.|. |.|||| AYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVT |
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Kinase | AqueK392.AA | TyrKc | 1-195 | 22 | 1.5e-14 | 12.72 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1-195 Range on HMM: 1-280/280 Sequence Identity: 22% (70 aa) IILESQLSEGAFGTVHKGYICGPASIPVAVKMNKS**G*SRSTERDRADEANKRREP------------------------PPHC*HDRLCHHTGA-DTA | |. .| |||||.|.|| |.||||| |. ..| .||. .. .|.. .. | |. . ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDY LHDNH*TRRSIEIPKTLCMPLPLPSLSFSLSLLLS--------*EYLSSIGIIHRDLACRNVLIDADKNLRISDFGMSRKVGGA------DEAYVKKT-- |.... . .... ||| |||.| ..||||||.||.|..... .|||||.||... .. |.||. LRKHRPK--------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHK RGR--LPWKWMAIESLTEREFSFKSDVWSYGVTLWEI--------------------------------------------------------------- |. || .|||.|.. ...|..||||||.||..||| GGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED ----------V RPTFSEIHECF |
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Kinase | AqueK392.AA | TK | 1-55 | 22 | 5.7e-09 | 25.4 | In-house | 1-96 (486) | Show / Hide |
Range on Protein: 1-55 Range on HMM: 1-96/486 Sequence Identity: 22% (22 aa) IILESQLSEGAFG---TVHKGYICGPAS------------------------IPVAVKMNKS**G*SRSTERD--------------RADEANKRR |.|. .| ||.|| .|.|| |. .|||||| |. . | ..| | |. . . ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMC |
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Kinase | AqueK392.AA | Pkinase | 112-196 | 34 | 7.7e-09 | 32.33 | Pfam | 122-207 (293) | Show / Hide |
Range on Protein: 112-196 Range on HMM: 122-207/293 Sequence Identity: 34% (31 aa) EYLSSIGIIHRDLACRNVLIDADKNL----RISDFGMSRKVGGADEAYVKKTRGRLPWKWMAIESLT-EREFSFKSDVWSYGVTLWEIVT ||. | ||||||| |.||| . .. .|.||| .... .|. || .|| | . .. . |.|.||.|..|.| .. EYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPW-YMAPEVIRGGQYYGPKVDMWSCGCILYEMLC |
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Kinase | AqueK392.AA | Fer | 1-35 | 31 | 5.6e-07 | 19.93 | In-house | 1-44 (283) | Show / Hide |
Range on Protein: 1-35 Range on HMM: 1-44/283 Sequence Identity: 31% (14 aa) IILESQLSEGAFGTVHKG------YI---CGPASIPVAVKMNKS ..|. .| |||||.|.|| . . . ...|.||..|. VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKC |
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Kinase | AqueK392.AA | TK-Unique | 1-34 | 35 | 1e-06 | 19.21 | In-house | 1-39 (294) | Show / Hide |
Range on Protein: 1-34 Range on HMM: 1-39/294 Sequence Identity: 35% (14 aa) IILESQLSEGAFGTVHKGYICG-----PASIPVAVKMNK . ..... |||||.|..| ..| . . |||||.| LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLK |
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Kinase | AqueK392.AA | S_TKc | 1-196 | 16 | 2.5e-05 | -98.84 | SMART | 1-220 (231) | Show / Hide |
Range on Protein: 1-196 Range on HMM: 1-220/231 Sequence Identity: 16% (43 aa) IILESQLSEGAFGTVHKGYICGPASIPVAVKMNKS**G*SRSTERDRADEANKRREPPPHC*HDRLCHHTGADTALHDNH*TRRSIEIPKTLCMPLPLPS . .. .||||.|.|.. . ||.|. | | . ... . . . .. . |.| . . . YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------------------------EHIRREIQILKK-HHPNIVKLYDVFQD----DHLYMVMEYCD L--------------------------SFSLSLLLS*EYLSSIGIIHRDLACRNVLIDADKNLRISDFGMSRKVGGADEAYVKKTRGRLPWKWMAIESLT .. ... ||. | ||||||| |.|.| .. |.|||..|.. | .|| | | GDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL- EREFSF-KSDVWSYGVTLWE------------------------------------------IVT ... |.|.|| |..|.| . . --GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ |
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Kinase | AqueK392.AA | Pkinase_Tyr | 1-32 | 48 | 4e-05 | 17.97 | Pfam | 1-35 (270) | Show / Hide |
Range on Protein: 1-32 Range on HMM: 1-35/270 Sequence Identity: 48% (17 aa) IILESQLSEGAFGTVHKGYIC---GPASIPVAVKM |.. .| |||||.|.||. . ||||||| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKM |
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Kinase | AqueK392.AA | RTKB | 1-21 | 33 | 0.001153 | 8.25 | In-house | 1-21 (264) | Show / Hide |
Range on Protein: 1-21 Range on HMM: 1-21/264 Sequence Identity: 33% (7 aa) IILESQLSEGAFGTVHKGYIC . | .| .|||| | ..... VWLGEKLGNGAFGEVFQAWVR |
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Kinase | AqueK392.AA | UTK | 1-18 | 55 | 0.001196 | 8.36 | In-house | 1-18 (296) | Show / Hide |
Range on Protein: 1-18 Range on HMM: 1-18/296 Sequence Identity: 55% (10 aa) IILESQLSEGAFGTVHKG ..| || .||||.|||. VQLGRQLGQGAFGEVHKA |
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Kinase | AqueK392.AA | Src | 1-31 | 45 | 0.004354 | 6.28 | In-house | 1-29 (255) | Show / Hide |
Range on Protein: 1-31 Range on HMM: 1-29/255 Sequence Identity: 45% (14 aa) IILESQLSEGAFGTVHKGYICGPASIPVAVK | |. .| .| || | .|| | ...|||| IKLCRKLGQGQFGEVWMGYWNG--NTKVAVK |
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Kinase | AqueK392.AA | Ack | 1-31 | 42 | 0.015285 | 4.4 | In-house | 1-33 (266) | Show / Hide |
Range on Protein: 1-31 Range on HMM: 1-33/266 Sequence Identity: 42% (14 aa) IILESQLSEGAFGTVHKGY--ICGPASIPVAVK | | .| .| || |..| | .|.|||| ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVK |
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Kinase | AqueK392.AA | FGFR | 1-35 | 34 | 0.022339 | 3.85 | In-house | 1-41 (293) | Show / Hide |
Range on Protein: 1-35 Range on HMM: 1-41/293 Sequence Identity: 34% (14 aa) IILESQLSEGAFGTVHKGYIC--GPA----SIPVAVKMNKS | . | ||.|| | .. .. | ||||| |. LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKM |
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Kinase | AqueK392.AA | Ret | 1-18 | 44 | 0.103315 | 1.57 | In-house | 1-18 (293) | Show / Hide |
Range on Protein: 1-18 Range on HMM: 1-18/293 Sequence Identity: 44% (8 aa) IILESQLSEGAFGTVHKG .|. | || || | |. LQLDDTLGEGHFGQVVKA |
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Kinase | AqueK392.AA | VEGFR | 1-18 | 44 | 0.260087 | 0.95 | In-house | 1-18 (332) | Show / Hide |
Range on Protein: 1-18 Range on HMM: 1-18/332 Sequence Identity: 44% (8 aa) IILESQLSEGAFGTVHKG . | .| .|||| ||.. LKLGKMLGRGAFGQVHEA |
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Kinase | AqueK392.AA | Pkinase | 1-31 | 30 | 3.726571 | 1.63 | Pfam | 1-30 (293) | Show / Hide |
Range on Protein: 1-31 Range on HMM: 1-30/293 Sequence Identity: 30% (10 aa) IILESQLSEGAFGTVHKGYICGPASIP--VAVK . ..... .|.||.| |.| . . |||| YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVK |