Gene AqueK389 (A.queenslandica)

AqueK389

Species: A.queenslandica
Alias: AqueK389
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK389.AA Protein None 600 None Fasta, JSON
AqueK389.kin_dom Protein Kinase Domain None 283 None Fasta, JSON

Protein domain

Protein domains of AqueK389.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TyrKc AqueK389.AA TyrKc 196-477 35 9.1e-114 385.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 196-477
Range on HMM: 1-280/280
Sequence Identity: 35% (110 aa)

ISMHGTIGQGEFGIVYHGVMTIENKIPEPVAIKTLKSFYKESDIESLLDECIIMMSF--NNLNVLPLIGVCLDLG------PAPYIIMPFMSKGSLLSYL
|..  ..| |.||.||.|...      ..||.|.||.      .| ...|  ||...  .. |.. |.|||.. |      . ..|.| .|..|.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERCNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVIKVADFGLSEDIYAC-------NYFRQLKGSDNNSGSST
.| | .            |.. |.|||.|.|.|.||.||.|...||||||||||....|...|..||||| |||          | |. ..       . 
RKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH-------KG

VK--LPVKWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPG-----LDPIGVVELLDTGKRLEPPRNAA------CSQEIYLLMFSCWSESSIDR
 |  ||..|||.|.. .| |..||||||.||..||.|..|. ||||     .... |.|....|.|...| |.       |..|.| .| .|| |   ||
GKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR

PVFSDLKITV
| ||...   
PTFSEIHECF
Pkinase_Tyr AqueK389.AA Pkinase_Tyr 196-477 38 2.6e-111 377.59 Pfam 1-270 (270) Show / Hide 
Range on Protein: 196-477
Range on HMM: 1-270/270
Sequence Identity: 38% (112 aa)

ISMHGTIGQGEFGIVYHGVMT-IENKIPEPVAIKTLKSFYKESD--IESLLDECIIMMSF-NNLNVLPLIGVCLDLGPA--PYIIMPFMSKGSLLSYLKK
|..  ..|.|.|| ||.|...  . .   |||.|.||  . ...  .|... |  ||... .. |.. |.|||.| |    .||.|..| .|.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERCNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVIKVADFGLSEDIYACNYFRQLKGSDN-NSGSSTVKLPVKWM
 |         |..  |..   ||..|.|.|.||.||.|...||||||||||....|.|.|..||||. ||         . .    .....  ||.|||
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--------YNDDYYYRKRGGGK-LPIKWM

ALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVP-YPGLDPIGVVELL-DTGKRLEPPRNAACSQEIYLLMFSCWSESSIDRPVFSDLKITV
|.|....| |..||||||.|||.||.|..|. | |||...  |.|.. . | |...|.|  |..||| || .|| .   ||| ||..    
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK389.AA TK 196-477 22 3.1e-95 319.7 In-house 1-486 (486) Show / Hide 
Range on Protein: 196-477
Range on HMM: 1-486/486
Sequence Identity: 22% (110 aa)

ISMHGTIGQGEFG---IVYHGVMTIEN----------------------KIPEPVAIKTLKSFYKESDIESLL-------------DECIIMMSFN----
| .  ..|.|.||    || | .  .|                      . ..|||.|.||.   .|. | ..              |. .|. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-NLNVLPLIGVCLDLG-----------PAPYIIMPFMSKGS----LLSYLKKERC-----------------------------NLTVADTSEEDIILNV
   |.. |.|||.. .           . ..|.| .|..|.    |..||.| |                              ..  .. .... . . 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY-SHESNSPC-PEEQ

---------------RKQLLS-------------------ICLQVANGMSYLASQ------RFIHRDLAARNCMIDDNGV-----------IKVADFG--
                |.||.                   .|.|.|.||.||.|.      .|.|||||||||....|.|           .|.||||  
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSEDIY-------------ACNYFRQLKGSDNNSGSS--------------TVKLPVKWMALESLHDGL---------FSEKSDVWSYGVLCWE
      |. |||             .... .           .                |||..||| |.| |.          |..||||||.|||.||
RQGSGVLARDIYSDDDYYRKSSYGTGRPM-W-----------PFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWE

VFSLGKVPYPGLDPI----------GVVELLDT------------GKRLEPPRNAACS--------------QEIYLLMFSCWSESSIDRPVFSDLKITV
.|..|..||.|  .            |.|.| .            | |...|. . |.              .|.|.|| .||..   ||| ||.|.   
IFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK389.AA Met 197-471 37 5.9e-90 295.1 In-house 1-271 (271) Show / Hide 
Range on Protein: 197-471
Range on HMM: 1-271/271
Sequence Identity: 37% (109 aa)

SMHGTIGQGEFGIVYHGVMTIENKIPEPVAIKTLK--SFYKESDIESLLDECIIMMSFNNLNVLPLIGVCLDLGP-APYIIMPFMSKGSLLSYLKKERCN
 .   |||| || |||| .. .    ...|.|.|.      .  |.  | | |.|  |.  ||| |||.|||     |... |.| .| |... . .  |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVIKVADFGLSEDI-YACNYFRQLKGSDNNSGSSTV--KLPVKWMAL
..|             ..|.. |.||| ||.|.|||.|.|||||.||||.|   ..|||||||. |. |   |  |         . |   .|||||||.
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQM--------HHTHPARLPVKWMAP

ESLH--------DGL-FSEKSDVWSYGVLCWEVFSLGKVPYPGLDP-IGVVELLDTG--KRLEPPRNAACSQEIY-LLMFSCWSESSIDRPVFS
|.|         .   |. |||||| ||. || .  | .|||  |. . .   | .|  .||  |    |   .|  .| .||. . .||| ||
ECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEY--CPDHLYTDVMLCCWHANPEDRPQFS
Kinase AqueK389.AA TK-Unique 196-477 31 2e-85 290.11 In-house 1-294 (294) Show / Hide 
Range on Protein: 196-477
Range on HMM: 1-294/294
Sequence Identity: 31% (97 aa)

ISMHGTIGQGEFGIVYHGVMTIEN---KIPEPVAIKTLKSFYKESDIESLLDECIIMMSFN-NLNVLPLIGVCLDLGPAPYIIMPFMSKGSLLSYLKKER
. .  .||.|.|| |..| ..  .     .  ||.|.||    . |   .|.|  .|..     |.. ..|.| . .  ..|||.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

C---------NLT-VADTSEEDIILN-VR-KQLLSICLQVANGMSYLAS--QRFIHRDLAARNCMIDDNGVIKVADFGLSEDIYACNYFRQLKGSDNNSG
.         ||   ... ...  .. .  |.|.... |.|.||.||||  ....||||.|||... ...|.|..|||...|.|.        . .... 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT--------NGVYSMM

SSTVKLPVKWMALESLH--DGLF-SEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGKRLEPPRNAAC-SQEIYLLMFSCWSESSIDRPVFSDL
 |  ..|..|||.|||   .| . ..||||||.||| ||.|.||. ||||...  ..|..  |.|.. |  . | |.|.| || |||...  .|| |...
CSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQP--EHCCSHEMYNLMKSCWQWEPEERPSFRQI

KITV
|   
KHRL
Kinase AqueK389.AA UTK 196-477 31 5.1e-79 268.84 In-house 1-296 (296) Show / Hide 
Range on Protein: 196-477
Range on HMM: 1-296/296
Sequence Identity: 31% (96 aa)

ISMHGTIGQGEFGIVYHGVMT-IENKIPE-PVAIKTLK-SFYKESDIE---SLLDECI---IMMSFN-NLNVLPLIGVCLDLGPAPYIIMPFMSKGSLLS
.    ..|||.||.|...  | . .  .|  ||.|... .  .. . |    .. |.    .|. |.   ||| |.|||.. .| ..|.. .|..|.|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLKKERCNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNG-------VIKVADFG---LSEDIY----ACNYFRQLKG
|| . | ..      ... .|. . |.|. ....|.||.||.|..|.||||||||| .....       |.|.||||   .| ...    .     . ..
YLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSN----RYWE

SDNNSGSSTVKLPVKWMALESLHDG-LFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGKRLEPPRNAACSQEIYLLMFSCWSESSIDRPVF
|.    ..  ..|..||| |.| ..  |..||||||.||.|||... |..||||.    |.. .  | |. .|....|. ..| || .||  .  .|| |
SYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDF

SDLKITV
 ||  ..
EDLVQQM
Kinase AqueK389.AA Axl 196-475 38 2.2e-73 250.11 In-house 1-267 (267) Show / Hide 
Range on Protein: 196-475
Range on HMM: 1-267/267
Sequence Identity: 38% (109 aa)

ISMHGTIGQGEFGIVYHGVMTIENKIPEPVAIKTLK-SFYKESDIESLLDECIIMMSFNNLNVLPLIGVCLDLG-----PAPYIIMPFMSKGSLLSYLKK
. .  ..|.|||| |  | .  |      ||.|..|     .|.||  | | . |  |.  ||. |||||. .      |.| .|.|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ERCNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVIKVADFGLSEDIYACNYFRQLKGSDNNSGSSTVKLPVKWMA
 | .       .. . | . . |.   . .| || ||....||||||||||||. ..  . |||||||  ||.  |.|| .           |.||||.|
SRLG-------DQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGC---------IAKMPVKWIA

LESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGKRLEPPRNAACSQEIYLLMFSCWSESSIDRPVFSDLKI
.||| | ..  |||||..||  ||.   |. ||||..   . . |  |.||  | .  | .|.| ||..||.    ||| || |. 
IESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPED--CMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase AqueK389.AA FGFR 196-473 34 2e-69 235.76 In-house 1-289 (293) Show / Hide 
Range on Protein: 196-473
Range on HMM: 1-289/293
Sequence Identity: 34% (104 aa)

ISMHGTIGQGEFGIVYHGVMT-IENK---IPEPVAIKTLKSFYKESDIESLLDECIIM-MSFNNLNVLPLIGVCLDLGPAPYIIMPFMSKGSLLSYLKKE
 ..  ..| | || |  .    |...       ||.| ||.   . |. .|  |  .| |   . |.. |.|.|   || .|.|  . ..| |  .|.. 
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGP-LYVIVEYCHHGNLRDFLRAR

RCNLTVADTSEE-------DIILNV----------RKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVIKVADFGLSEDIYACNYFRQLKGSD
|     .. . .        .   .           |.| |.  ||| || ||||.. |||||||||  . |. |.|..||||. ||    |.|      
RPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRK-----

NNSGSSTVKLPVKWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLD-PIGVVELLDTGKRLEPPRNAACSQEIYLLMFSCWSESSIDRPVFSD
.  |     ||.||||.|.| |  .  .||||||||| ||.. .|  |||.        ..| .|.|.|.| |  |||||| .| .|| ... .|| |  
TTNG----RLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQ

L
|
L
Kinase AqueK389.AA Src 196-477 36 5.7e-68 230.0 In-house 1-255 (255) Show / Hide 
Range on Protein: 196-477
Range on HMM: 1-255/255
Sequence Identity: 36% (105 aa)

ISMHGTIGQGEFGIVYHGVMTIENKIPEPVAIKTLKSFYKESDIESLLDECIIMMSFNNLNVLPLIGVCLDLGPAPYIIMPFMSKGSLLSYLKKERCNLT
| .   .||| || |. |.    ...  .||.||||.     . | .| |  || ..   ... |  || .  |  ||.  .||.|||| ||||      
IKLCRKLGQGQFGEVWMGYW--NGNT--KVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKK------

VADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVIKVADFGLSEDIYACNYFRQLK-GSDNNSGSSTVKLPVKWMALESLH
    ..|   |... ||...  |||.||.|| |...|||||||||  ...| | |||||||          | .| . |. . ..  |.|.||.| | ..
----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLA---------RLIKEDDDEYCARHGAKFPIKWTAPEAIN

DGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGKRLEPPRNAACSQEIYL-LMFSCWSESSIDRPVFSDLKITV
 | |. ||||||.|.| .|... |.||||| .   |.. .. | |.  |. . | .|.|  .|  || ..  .|| |  |    
YGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRM--PCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK389.AA ALK 196-477 38 6.6e-68 231.92 In-house 1-273 (273) Show / Hide 
Range on Protein: 196-477
Range on HMM: 1-273/273
Sequence Identity: 38% (113 aa)

ISMHGTIGQGEFGIVYHGVMTI--ENKIPEPVAIKTLKSFYKESDIESLLDECIIMMSFNNLNVLPLIGVCLDLGPAPYIIMPFMSKGSLLSYLKKERCN
|      |.| || || |  .       | .||.|||.   .. | |  . |  ||  ||  ||  .||.|..  |  .|.  .|. | ..|.|.  | .
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH

LTVADTSEE--DIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNG---VIKVADFGLSEDI-YACNYFRQLKGSDNNSGSSTVKLPVKW
       .|     . . | || .|. || |  || ...||||| |||||     |   | |.|||| . || |   |.|         |  .  .||||
-------PESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRK--------GGRAM-MPVKW

MALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGKRLEPPRNAACSQEIYLLMFSCWSESSIDRPVFSDL--KITV
|  | . ||.|  |.||||.||||||.|||| .||||     | |.. .| |..||||  | | .| .|  ||     ||| | ..  .|. 
MPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase AqueK389.AA InsR 196-480 35 9.5e-66 219.79 In-house 1-278 (278) Show / Hide 
Range on Protein: 196-480
Range on HMM: 1-278/278
Sequence Identity: 35% (103 aa)

ISMHGTIGQGEFGIVYHG----VMTIENKIPEPVAIKTLKSFYKESDIESLLDECIIMMSFNNLNVLPLIGVCLDLGPAPYIIMPFMSKGSLLSYLKKER
| .    ||| || || |    ..  |  .  ..||||..      .    | |  .|  ||  .|  | |||    |. |..| .| .| | |||   |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPM-YVVMEMMTYGDLKSYLRSRR

CNLTVADTSEEDII----LNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVIKVADFGLSEDIYACNYFRQLKGSDNNSGSSTVKLPVKW
         . ...       . |...   ... ||.|||.  |.|||||.||||... . .|..|||.  |||   | |  ...         .||| |
PEEEF---NNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKG---------MLPVRW

MALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELL-DTGKRLEPPRNAACSQEIYLLMFSCWSESSIDRPVFSDLKITVICF
|| ||| || |. .|||||.||. ||. .||  || ||    | .     |. |.|| |  |..  . ||  ||  .. .|| | |. |  .| 
MAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPEN--CPEYWQELMMMCWQYQPKMRPTFLDI-IHYLCD
Kinase AqueK389.AA Abl 196-477 38 6.7e-65 215.28 In-house 1-252 (252) Show / Hide 
Range on Protein: 196-477
Range on HMM: 1-252/252
Sequence Identity: 38% (108 aa)

ISMHGTIGQGEFGIVYHGVMTIENKIPEPVAIKTLKSFYKESDIESLLDECIIMMSFNNLNVLPLIGVCLDLGPAPYIIMPFMSKGSLLSYLKKERCNLT
|.|.  .| | .| || ||    ...   ||.||||      ...  | |  ||      |.  |.|||    |  |||  ||..| || ||..      
IMMKHKLGGGQYGEVYEGVWKRHDCT---VAVKTLKE--DTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPF-YIITEFMCYGNLLDYLRE------

VADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVIKVADFGLSEDIYACNYFRQLKGSDNNSGSSTVKLPVKWMALESLHD
 .| .| . .      || .  |.| ||||| .. |||||||||||.. .. ..|||||||.  .    |  .             | |.|| | |||  
-CDREELPAVV-----LLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAH----------AGAKFPIKWTAPESLAY

GLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGKRLEPPRNAACSQEIYLLMFSCWSESSIDRPVFSDLKITV
  || ||||| .||| ||.   |  ||||.|   | ..|. | |.| |.   | ...| ||  ||  |  ||| | ..  ..
NKFSSKSDVWAFGVLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPE--GCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK389.AA S_TKc 196-478 20 1.1e-30 109.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 196-478
Range on HMM: 1-231/231
Sequence Identity: 20% (62 aa)

ISMHGTIGQGEFGIVYHGVMTIENKIPEPVAIKTLKSFYKESDIESLLDECIIMMSFNNLNVLPLIGVCLDLGPAPYIIMPFMSK--GSLLSYLKKERCN
  .. .||.| || || .. .      . |||| .|        |... |  |... .  |.  |..|. |     |..| ...   |.|..|.|| ...
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVIKVADFGLSEDIYACNYFRQLKGSDNNSGSSTVKLPVKWM
     ..  ..              ... |..... |. |...|||||   | ..|.  .||..||||.  .                  .|.     .|
GLRFPFPE-HAR-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFCGTPWYM

ALESLHDGLFSE-KSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGKRLEPPRNAACSQEIYLLMFSCWSESSIDRPVFSDLKI--------TVI
| | |    ..  |.|.|| |.. .| .. |. |.|        ..  . |..        |.|   ..  |.     .||   ..            .
APEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK389.AA Pkinase 196-468 22 1.8e-28 101.77 Pfam 1-282 (293) Show / Hide 
Range on Protein: 196-468
Range on HMM: 1-282/293
Sequence Identity: 22% (70 aa)

ISMHGTIGQGEFGIVYHGVMTIENKIPEPVAIKTLKSFYKES--DIESLL-DECIIMMSFNNLNVLPLIGVCLDLGPAPYIIMPFMSKG----SLLSYLK
.  ...||.| || ||...   ..|    ||.|..|   ..|  |.. ..  |. || ..|  |.. |.... | .. .|..|... .|    .| .|..
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

KERCNLTVADTSEEDIIL--NVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGVI----KVADFGLSEDIYACNYFRQLKGSDNNSGSSTVK
            ...  .     ... ....|.. |. |. |...|||||   |..||.||.|    |..||||.. ..            |||  .|. 
T-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTFC

LPVKWMALESLH-DGLFSEKSDVWSYGVLCWEVFSLGKVPYPGL----DPIGVVELLDTGKR--LEPPRNAACS-------------------QEIYLLM
    .|| | .  .   . |.|.||.|....|... |. |.||     . .   ....  ..  |. ..   ||                   .|   ..
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI

FSCWSESSIDRP
 .|.     .||
KWCLCKDPKKRP
SR AqueK389.AA SR 496-597 42 4.7e-44 153.6 SMART 1-118 (118) Show / Hide 
Range on Protein: 496-597
Range on HMM: 1-118/118
Sequence Identity: 42% (50 aa)

VHLVNGSGPNVGRLEICING----DWGTVCDDMWSHTNAQVVCRQLGYSTDGAVFLE----KAFFGAGNGSILLDDVVCSGSEDTILQCRHSSFGSHN--
| ||.|..|. ||.|. .||     ||||||| |. ..|.|||||||...  ..  .     |.||.|.| |..|.| |.|.|... .|.|...|.||  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CVH------DEDVGVHCS
| |      .||.||.||
CSHNHHRNRQEDAGVVCS
SRCR AqueK389.AA SRCR 499-597 45 4.9e-38 129.58 Pfam 1-112 (112) Show / Hide 
Range on Protein: 499-597
Range on HMM: 1-112/112
Sequence Identity: 45% (51 aa)

VNGSGPNVGRLEICI-NGDWGTVCDD-M-WSHTNAQVVCRQLGYSTDGAVF-LEKAF--FG--AGNGSILLDDVVCSGSEDTILQCRHSSFGS--HN--C
|.||.|. ||.|..  || |||||||   |. ..|.|||||||.  ...      |.  ||  .|.| |..|.| |.|.|... ||.||. |   ||  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

VHD-EDVGVHCS
 |. ||.|| ||
SHSREDAGVICS