Gene AqueK378 (A.queenslandica)

AqueK378

Species: A.queenslandica
Alias: AqueK378
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK378.AA Protein None 698 None Fasta, JSON
AqueK378.kin_dom Protein Kinase Domain None 275 None Fasta, JSON

Protein domain

Protein domains of AqueK378.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SR AqueK378.AA SR 21-127 38 5.4e-43 150.08 SMART 1-118 (118) Show / Hide 
Range on Protein: 21-127
Range on HMM: 1-118/118
Sequence Identity: 38% (46 aa)

VRLADGRVETEGRVEICIGD----SWGTVCDDRFTNINAAVVCRQIGYTTNFTPVTVYR-SRAYFGMGSGRILLDEIICNGSESRLVDCDMDRESIGTHD
|||..|. . |||||. ...    .|||||||...  .| ||||| |. .  . ..  . ..|.|| |||.|..|.. |.|.|..| ||    ...| |.
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPH--WGWGQHN

--CDH------SEDVGVICT
  |.|      .||.||.|.
NCCSHNHHRNRQEDAGVVCS
SRCR AqueK378.AA SRCR 24-127 37 7.3e-41 139.07 Pfam 1-112 (112) Show / Hide 
Range on Protein: 24-127
Range on HMM: 1-112/112
Sequence Identity: 37% (42 aa)

ADGRVETEGRVEICI-GDSWGTVCDD-R-FTNINAAVVCRQIGYTTNFTPVTVYRSRAYFG--MGSGRILLDEIICNGSESRLVDCDMDRESIGTHD--C
..|..  |||||..  ...|||||||   ... .| ||||| |.  .   ..  ...|.||   |.|.|..|.. |.|.|..| .| ..  . ..|.  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

DHS-EDVGVICT
.|| ||.||||.
SHSREDAGVICS
Pkinase_Tyr AqueK378.AA Pkinase_Tyr 407-681 39 2.5e-109 370.92 Pfam 1-270 (270) Show / Hide 
Range on Protein: 407-681
Range on HMM: 1-270/270
Sequence Identity: 39% (113 aa)

IALQETIGE--FGIVYRALLS-MENGAPQPVAVKTLKGSFTQND--VESIVDECIRMMSF-DNVNVLHLIGVCI-DMGP-APYIVMPFMAKGSLLSYLKK
| . ...||  || ||.. .   . .  .|||||.|| . .. .   |.   |   |... .. |.. |.|||. . .|  .||||..|..|.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERHNLTVAESSDDDIVLDVRKKLVSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHGIIKVADFGLTEEVYANNYFKQLKDNNASVKLPIKWMALESLH
 |         .|.  |..   |...|.|.|||| ||.|.|.|||||| |||.... ...|..||||.  .|   |    |  ..   |||||||.|...
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGK--LPIKWMAPECIN

DGLFSEKSDVWSYGVLCWEVFSLGRTP-YPGLDPAGVVDLL-DTGGRLQCPHNTACSQEIYMLMLSCWYELVSDRPLFSELVASL
.| |..||||||.|||.||.|..|..| |||.... |.... . |.|. ||.|  |..|||.||..|| .  .||| |||..  |
YGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc AqueK378.AA TyrKc 407-681 34 1.6e-104 354.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 407-681
Range on HMM: 1-280/280
Sequence Identity: 34% (104 aa)

IALQETIGE--FGIVYRALLSMENGAPQPVAVKTLKGSFTQNDVESIVDECIRMMSF--DNVNVLHLIGVCIDMG------PAPYIVMPFMAKGSLLSYL
| | ...||  ||.||.. ..      ..||||.|| .     .| . .|   |...  .. |.. |.|||.. |      . ..||| .|..|.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERHNLTVAESSDDDIVLDVRKKLVSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHGIIKVADFGLTEEVYAN-------NYFKQLKDNNASVKLPI
.| |..                |.|.|.|.|.|.|| ||.|.|.|||||| |||.... ...|..||||. ..|          | .. .  ..   |||
RKHRPK-------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

KWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGRTPYPG-----LDPAGVVDLLDTGGRLQCPHNTA------CSQEIYMLMLSCWYELVSDRPLFSELV
.|||.|.. .| |..||||||.||..||.|..| .||||     .... |. ....|.|. .|.|        |..|.|..|..|| |  .||| |||..
RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH

ASL
  .
ECF
Kinase AqueK378.AA TK 407-681 22 2.4e-93 313.26 In-house 1-486 (486) Show / Hide 
Range on Protein: 407-681
Range on HMM: 1-486/486
Sequence Identity: 22% (111 aa)

IALQETIGE--FG---IVYRALLSMEN----------------------GAPQPVAVKTLKGSFTQNDVESIV---------------DECIRMMS---F
| | ...||  ||    ||.... ..|                      |...|||||.||   .... | .                 | . ||.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNVNVLHLIGVCIDMG-----------PAPYIVMPFMAKGS----LLSYLKKERHNLTVAESSDDDIVLDVRK---------------------------
.  |...|.||| . .           . ..||| .|..|.    |..||.| |.. .  ... |.   ...                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------------------------------KLVSICLQVAKGMCYLASH------NFIHRDLASRNCMIDDHGI-----------IKVADFG---
                                    |. .|.|.|.|| ||.|.      ||.||||| |||.......           .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LTEEVYAN-NYFKQLKDNNA-------------------SVKLPIKWMALESLHDGL---------FSEKSDVWSYGVLCWEVFSLGRTPYPG-L
     |. ..| . .| ..     .                   . ||||.||| |.| |.          |..||||||.|||.||.|..|..||.| .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DP---------AGVVDLLDTGGR------------LQCPHNTACS--------------QEIYMLMLSCWYELVSDRPLFSELVASL
.          . |...| .|||            ...|    |.              .|.| ||..|| .  .||| ||.|.  |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK378.AA TK-Unique 407-681 31 5.3e-85 288.7 In-house 1-294 (294) Show / Hide 
Range on Protein: 407-681
Range on HMM: 1-294/294
Sequence Identity: 31% (93 aa)

IALQETIGE--FGIVYRALLS---MENGAPQPVAVKTLKGSFTQNDVESIVDECIRMMSFD-NVNVLHLIGVCIDMGPAPYIVMPFMAKGSLLSYLKKER
. ....|||  || |.|. ..   ....... ||||.|| ..|. |.    .|   |.. .   |.....|.|.. .  ..|.|.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

HN-----------LTVAESSDDDIVLDVR-KKLVSICLQVAKGMCYLAS--HNFIHRDLASRNCMIDDHGIIKVADFGLTEEVYANNYFKQLKDNNASVK
 .            ...   |..   ..  | |.... |.|.|| ||||  ....||||..||... .....|..|||....||.    ...  .  . .
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT---NGVYSMMCSQGR

LPIKWMALESLH--DGLF-SEKSDVWSYGVLCWEVFSLGRTPYPGLDPAGVVDLLDTGGRLQCPHNTAC-SQEIYMLMLSCWYELVSDRPLFSELVASL
.||.|||.|||   .| . ..||||||.||| ||.|.|| .||||.... .....  | |.. | .  | |.|.| || ||| .  ..|| |....  |
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK378.AA Met 408-675 36 3.1e-82 269.37 In-house 1-271 (271) Show / Hide 
Range on Protein: 408-675
Range on HMM: 1-271/271
Sequence Identity: 36% (104 aa)

ALQETIGE--FGIVYRALLSMENGAPQPVAVKTLK--GSFTQNDVESIVDECIRMMSFDNVNVLHLIGVCIDMGP-APYIVMPFMAKGSLLSYLKKERHN
.. . ||   || ||.. .. . |   ..|.|.|.     . . ..    | | |  ||  ||| |||.|.|     |..| |.|..| |... . . .|
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LTVAESSDDDIVLDVRKKLVSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHGIIKVADFGLTEEV-YANNYFKQLKDNNASVKLPIKWMALESLH---
..|             . |.. |.|||||| |.||  |.||||| ||||.| | ..|||||||   . |   |  | ..  .  .||.||||.|.|    
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQ-MHHTHPARLPVKWMAPECLQQGV

-----DGL-FSEKSDVWSYGVLCWEVFSLGRTPYPGLDP-AGVVDLLDTG--GRLQCPHNTACSQEIY-MLMLSCWYELVSDRPLFS
     .   |. |||||| ||. || .  | .|||  |.   .   | .|   ||  |  . |   .|  .||.||     ||| ||
CLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQP--EYCPDHLYTDVMLCCWHANPEDRPQFS
Kinase AqueK378.AA UTK 407-681 31 1.1e-76 261.14 In-house 1-296 (296) Show / Hide 
Range on Protein: 407-681
Range on HMM: 1-296/296
Sequence Identity: 31% (97 aa)

IALQETI--GEFGIVYRALLSMEN--GAPQPVAVKTLK-GSFTQNDVE---SIVDECI---RMMSFD-NVNVLHLIGVCIDMGPAPYIVMPFMAKGSLLS
..| ...  |.||.|..| .  ..  .  . ||||... ....| . |    .  |.     |. |.  .||| |.||| . .| ..||. .|..|.|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLKKERHNLTVAESSDDDIVLDVRKK-LVSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHG-------IIKVADFG---LTEEVY----ANNYFKQLK
|| . |...        .  . ...  ... ....| || ||.|..|.||||| ||| ...|.       ..|.||||   .. .|.    .| |  .. 
YLRRHRPTPP-------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYY

DNNA-SVKLPIKWMALESLHDG-LFSEKSDVWSYGVLCWEVFSLGRTPYPGLDPAGVVDLLDTGGRLQCPHNTACSQEIYMLMLSCWYELVSDRPLFSEL
 . .   ..||.||| |.| ..  |..||||||.||.|||... ||.||||.  . |.  .  |||.. | . .|. ..|.||..||.  ...|| | .|
YMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDL

VASL
|. .
VQQM
Kinase AqueK378.AA FGFR 407-681 35 6.2e-71 241.01 In-house 1-293 (293) Show / Hide 
Range on Protein: 407-681
Range on HMM: 1-293/293
Sequence Identity: 35% (106 aa)

IALQETIGE--FGIVYRALLS-MENG---APQPVAVKTLKGSFTQNDVESIVDECIRM-MSFDNVNVLHLIGVCIDMGPAPYIVMPFMAKGSLLSYLKKE
  | ...||  || | .|    ...    .   |||| || . |  |  . | |   | |   . |.. |.|.|   || .|..  . ..| |  .|.. 
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGP-LYVIVEYCHHGNLRDFLRAR

RHNLTVAESSDD-------DIVLDV----------RKKLVSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHGIIKVADFGLTEEVYANNYFKQLKDNN
|     .... .        .  ..           |.|||.  |||.|| ||||   |||||| ||  . |  ..|..||||   .  . |..  |  |
RPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYR--KTTN

ASVKLPIKWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGRTPYPGLD-PAGVVDLLDTGGRLQCPHNTACSQEIYMLMLSCWYELVSDRPLFSELVASL
    |||||||.|.| |  .  .||||||||| ||.. .| .|||.        ..| .| |.  |||  ||||||..| .|| .  ..|| | .|| .|
G--RLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase AqueK378.AA Axl 407-679 39 2e-70 240.27 In-house 1-267 (267) Show / Hide 
Range on Protein: 407-679
Range on HMM: 1-267/267
Sequence Identity: 39% (112 aa)

IALQETI--GEFGIVYRALLSMENGAPQPVAVKTLK-GSFTQNDVESIVDECIRMMSFDNVNVLHLIGVCIDMG-----PAPYIVMPFMAKGSLLSYLKK
..|  ..  |||| |  . |  | |. . ||||..|   .|| ..|  . | . |  ||  ||..|||||| |      |.| ...|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ERHNLTVAESSDDDIVLDVRKKLVSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHGIIKVADFGLTEEVYANNYFKQLKDNNASVKLPIKWMALESLH
 | .       |. . | . . ||   . .| || ||...|||||||| ||||. .   . ||||||   .|.  |..|        |.|.||.|.||| 
SRLG-------DQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQ----GCIAKMPVKWIAIESLA

DGLFSEKSDVWSYGVLCWEVFSLGRTPYPGLDPAGVVDLLDTGGRLQCPHNTACSQEIYMLMLSCWYELVSDRPLFSELVA
| ..  |||||..||  ||.   |.|||||.. . . | |  | ||. |..  | .|.| || .||     ||| ||.|  
DRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPED--CMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase AqueK378.AA Src 433-681 38 4.3e-67 226.98 In-house 25-255 (255) Show / Hide 
Range on Protein: 433-681
Range on HMM: 25-255/255
Sequence Identity: 38% (96 aa)

PVAVKTLKGSFTQNDVESIVDECIRMMSFDNVNVLHLIGVCIDMGPAPYIVMPFMAKGSLLSYLKKERHNLTVAESSDDDIVLDVRKKLVSICLQVAKGM
.|||||||      ..|    |   | ...  ....|  || .  |  |||  .|..|||| ||||          ...   | .. .|...  |||.||
KVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKK----------DGEGRHLHLP-QLIDMAAQVAEGM

CYLASHNFIHRDLASRNCMIDDHGIIKVADFGLTEEVY--ANNYFKQLKDNNASVKLPIKWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGRTPYPGLD
.|| | |.|||||| ||  .... . |||||||   .    ..|  .        |.||||.| | .. | |. ||||||.|.| .|... ||.|||| .
AYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARH-----GAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMT

PAGVVDLLDTGGRLQCPHNTACSQEIYM-LMLSCWYELVSDRPLFSELVASL
 . |.. .. | |. ||||  | .|.|. .|| || .   .|| |  |   |
NHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK378.AA EGFR 433-682 35 3.1e-64 212.12 In-house 30-258 (258) Show / Hide 
Range on Protein: 433-682
Range on HMM: 30-258/258
Sequence Identity: 35% (89 aa)

PVAVKTLKGSFTQNDVESIVDECIRMMSFDNVNVLHLIGVCIDMGPAPYIVMPFMAKGSLLSYLKKERHNLTVAESSDDDIVLDVRKKLVSICLQVAKGM
|||.| |. .  ..  | ..||   | | |..... |.|||  |..   .|  .|  |.|| |... . |.               ..|.  |.|.||||
PVAIKVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLGVC--MHSQMQLVTQYMPYGCLLDYVRQHKDNIGS-------------QHLLNWCVQIAKGM

CYLASHNFIHRDLASRNCMIDDHGIIKVADFGLTEEVYANNYFKQLKDNNASVKLPIKWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGRTPYPGLDPA
 ||  |  .||||| || ..     .|..|||| .   ...  |... . .  |.||||||||..| . .  .|||||||| |||.   |  || |.  .
QYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDE--KEYHAQGG--KMPIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFGQKPYDGIPAR

GVVDLLDTGGRLQCPHNTACSQEIYMLMLSCWYELVSDRPLFSELVASLD
 . |||. | ||. | .  |.. .||.|..||      || | ||.. ..
EIPDLLEKGERLPQPPI--CTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase AqueK378.AA Tec 407-683 35 1.7e-62 213.93 In-house 1-254 (254) Show / Hide 
Range on Protein: 407-683
Range on HMM: 1-254/254
Sequence Identity: 35% (100 aa)

IALQETIGE--FGIVYRALLSMENGAPQPVAVKTLK-GSFTQNDVESIVDECIRMMSFDNVNVLHLIGVCIDMGPAPYIVMPFMAKGSLLSYLKKERHNL
... . .|   ||.| .. .  .      ||.|..| ||    |    ..|   ||     .   | |||.   |  |||  .|..|.||.||....| .
LTFMKELGSGQFGVVHLGKWRHQ----YDVAIKMIKEGSMSEED---FIEEAKVMMKLSHPKLVQLYGVCSQQRPI-YIVTEYMEHGCLLNYLREHKHHF

TVAESSDDDIVLDVRKK--LVSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHGIIKVADFGLTEEVYANNYFKQLKDNNASV--KLPIKWMALESLHD
              ..   | ..|..| .|| || .|.||||||| ||| ..| ...||.|||.|  |    |         ||  | |.|| . | .| 
Q-------------KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYT-------SSVGTKFPVKWCPPEVFHY

GLFSEKSDVWSYGVLCWEVFSLGRTPYPGLDPAGVVDLLDTGGRLQCPHNTACSQEIYMLMLSCWYELVSDRPLFSELVASLDG
  .| |||||..||| |||||.|. ||. ..   ||.   .| ||  ||   ||..||  | .|| |   .|| |..|  ..  
SRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPH--LCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK378.AA Fer 407-682 31 2.9e-62 210.87 In-house 1-283 (283) Show / Hide 
Range on Protein: 407-682
Range on HMM: 1-283/283
Sequence Identity: 31% (93 aa)

IALQETIGE--FGIVYRA------LLSMENG-APQPVAVKTLKGSFTQND-VESIVDECIRMMS-FDNVNVLHLIGVCIDMGPAPYIVMPFMAKGSLLSY
. |.. .||  ||.||..      ....     . .|.||..|..... .  . .  |   |.. .|  ||  ..||| |  |  .||| |.  |||.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPI-MIVMEFCNGGSLDSY

LKKERH-NLTVAESSDDDIVLDVRKKLVSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHGIIK---VADFGLTEEVYANNYFKQLKDNNASVKLPIKW
|||. . .....|             .. .|.|.|.|| || |.| ||||.|.||| ...... |   ..|||.  .   . | ...|.  .. |.||.|
LKKNKNKTVSDNE-------------KIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE--KACKVPIRW

MALESLHDGLFSEKSDVWSYGVLCWEVFSLGRTPYPG----LDPAGV--VDLLD-TGGRLQCPHNTACSQEIYMLML-SCWYELVSDRPLFSELVASLD
.| |.. .|..|.|.||||.||.|||.|. | .||||    . .. |   .    . ..   |.   .  ||. .|. .|| .  .||| ..|..  | 
LAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK378.AA S_TKc 407-689 21 1.7e-26 95.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 407-689
Range on HMM: 1-231/231
Sequence Identity: 21% (64 aa)

IALQETIGE--FGIVYRALLSMENGAPQPVAVKTLKGSFTQNDVESIVDECIRMMSFDNVNVLHLIGVCIDMGPAPYIVMPFMAK--GSLLSYLKKERHN
  . ..||.  || ||..         . ||.| .|        |.|  |   ... .  |. .|..|. |     |.|| ..    |.|..|.|| ...
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LTVAESSDDDIVLDVRKKLVSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHGIIKVADFGLTEEVYANNYFKQLKDNNASVKLPIKWMALESL
     ..  .               ... |..... |. ||..|||||   | ..|.   ||..||||  ..              ..     .|| | |
GLRFPFPE-H-------------ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL

HDGLFSE-KSDVWSYGVLCWEVFSLGRTPYPGLDPAGVVDLLDTGGRLQCPHNTACSQEIYMLMLSCWYELVSDRPLFSELVA-SLDGIIMPLA
    ..  |.|.|| |.. .| .. |..|.|      .  ...  |          |.|   ..  |.    ..||   |. .  .|  ..|  
---GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK378.AA Pkinase 407-565 23 2.8e-14 51.56 Pfam 1-158 (293) Show / Hide 
Range on Protein: 407-565
Range on HMM: 1-158/293
Sequence Identity: 23% (42 aa)

IALQETIGE--FGIVYRALLSMENGAPQPVAVKTLKGSFTQNDVESIVD----ECIRMMSFDNVNVLHLIGVCIDMGPAPYIVMPFMAKG----SLLSYL
. . ..||.  || ||..   .. | .. ||||..| . .... . . .    |.  | ...  |.. |.... | .. .|.||... .|    .| .|.
YHIGRKIGSGSFGCVYKC---HHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYI

KKERHNLTVAESSDDDIVLDVRKKL-------VSICLQVAKGMCYLASHNFIHRDLASRNCMIDDHGII----KVADFGL
.                  . ....        ....|...|. |. |...||||| . |..||..| |    |..||||
ST-----------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase AqueK378.AA Pkinase 603-681 18 4.1e-05 19.15 Pfam 190-293 (293) Show / Hide 
Range on Protein: 603-681
Range on HMM: 190-293/293
Sequence Identity: 18% (19 aa)

SEKSDVWSYGVLCWEVFSLGRTPYPGL-----DPAGVVDLLDTGGRLQCPHNTACS-------------------QEIYMLMLSCWYELVSDRPLFSELV
. |.|.||.|....|... ||.|.||      .   ..  .. |..|  .  . ||                   .|   .. .|.    ..|| . ...
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

AS--L
 .  .
QHPWF