AqueK369

Species: A.queenslandica
Alias: AqueK369
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK369.AA Protein None 336 None Fasta, JSON
AqueK369.kin_dom Protein Kinase Domain None 272 None Fasta, JSON

Protein domain

Protein domains of AqueK369.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TyrKc AqueK369.AA TyrKc 35-306 32 4.4e-97 329.75 SMART 1-280 (280) Show / Hide
Range on Protein: 35-306
Range on HMM: 1-280/280
Sequence Identity: 32% (102 aa)

LTIQESVGQGEFGIVYRGLISVKNDIPQAIAAKTLKGFYSKSDIDSLLDECIIMMSF--DNLNVLPLIGVCLD-----------------LGPGSLLSYL
.|  .  | |.||.||.|  .      .  | |.||       .  ...|  ||...  .. |.. |.|||..                    |.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERANLTVADTSEEDIVLNVRKQLLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYAK-NYFRQFKRNTNESPSLTT-----
.| | .            |.. |.|||.|.|.|.|| ||.|...||||||||||....|...|..||||| ||| . .          || .  .     
RKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--------ESKDYYRKKEHK

-VK--LPVKWMAIESLHDGLFSEKTDVWSYGILCWEVFSLGRVPYPG-----LDPVGVVEFLDTGGRLLAPRGEA------CSKEIYSLMTSCWSESPDD
  |  ||..|||.|.. .| |..|.||||.|...||.|..|  ||||     ...  |.|....|.|.  |          |..|.|..|..|| | |.|
GGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED

RPVFSDLVSSI
|| ||.... .
RPTFSEIHECF

Kinase AqueK369.AA TK 35-306 22 8.9e-91 304.5 In-house 1-486 (486) Show / Hide
Range on Protein: 35-306
Range on HMM: 1-486/486
Sequence Identity: 22% (110 aa)

LTIQESVGQGEFG---IVYRGLISV----------------------KNDIPQAIAAKTLKGFYSKSDIDSLL---------------DECIIMMS---F
.|. .  |.|.||    ||.|.                         |.. ..  | |.||   . |. . ..                | . ||.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNLNVLPLIGVCLDLGP----------------------GS----LLSYLKKERANLTVA---------------------------------DTSEEDI
.  |.. |.|||.. .|                      |.    |..||.| | . .                                   . .||. 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

VLNV----------RKQLLS-------------------ICLQVANGMCYLASQ------RFIHRDLAARNCMIDDNGI-----------IKVADFG---
...            |.||.                   .|.|.|.|| ||.|.      .|.|||||||||....|..           .|.||||   
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSEDIYA-KNYFRQFKRNTNESPSL--------------TTVKLPVKWMAIESLHDGL---------FSEKTDVWSYGILCWEVFSLGRVPYPGL
     |. |||  ..| |.  . |.  .                .  |||..||| |.| |.          |..|.||||.|.|.||.|..|..||.| 
QGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

DPV----------GVVEFLDTGGR------------LLAPRGEACS--------------KEIYSLMTSCWSESPDDRPVFSDLVSSI
 .            |.|.| .|||            .  |. . |.              .|.| ||..||.. |.||| ||.|.. .
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK369.AA TK-Unique 35-306 31 1.4e-78 267.36 In-house 1-294 (294) Show / Hide
Range on Protein: 35-306
Range on HMM: 1-294/294
Sequence Identity: 31% (95 aa)

LTIQESVGQGEFGIVYRGLISVKN---DIPQAIAAKTLKGFYSKSDIDSLLDECIIMMSFD-NLNVLPLIGVCLDLG-----------PGSLLSYLKKER
|......|.|.|| |.|| .. ..   | .. .| |.||   .. | . .|.|  .|.. .   |.. ..|.| . .           .|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

---------ANLTVADTSEEDIVLN--VR-KQLLSICLQVANGMCYLAS--QRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYAKNYFRQFKRNTNESP
         .||     ...|....  .  |.|.... |.|.|| ||||  ....||||.|||... .....|..|||...|.|.         |.  | 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT---------NGVYSM

SLTTVKLPVKWMAIESLH--DGLF-SEKTDVWSYGILCWEVFSLGRVPYPGLDPVGVVEFLDTGGRLLAPRGEAC-SKEIYSLMTSCWSESPDDRPVFSD
. .  ..|..||| |||   .| . ..|.||||.|.| ||.|.||  ||||...  ..| .  | |.. |  | | |.|.|.|| |||...|..|| |..
MCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQP--EHCCSHEMYNLMKSCWQWEPEERPSFRQ

LVSSI
... .
IKHRL

Kinase AqueK369.AA UTK 35-306 30 1.2e-71 244.3 In-house 1-296 (296) Show / Hide
Range on Protein: 35-306
Range on HMM: 1-296/296
Sequence Identity: 30% (92 aa)

LTIQESVGQGEFGIVYRGLI-SVKNDIPQ-AIAAKTLKGFYSKSD----ID---SLLDECI---IMMSFD-NLNVLPLIGVCLDLGP----------GSL
. . .  |||.||.|...    ...  .. . | |...   ...|     .    .. |.    .|. |.   ||| |.|||.. .|          |.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDL

LSYLKKERANLTVADTSEEDIVLNVRKQLLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNG-------IIKVADFG---LSEDIYAKNYFRQFKRNT
.||| . | ..      ...  |. . |.|. ....|.|| ||.|..|.||||||||| .....       ..|.||||   .| ....   |     ..
RSYLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFH-FSNRYWES

NESPSLTTVKLPVKWMAIESLHDG-LFSEKTDVWSYGILCWEVFSLGRVPYPGLDPVGVVEFLDTGGRLLAPRGEACSKEIYSLMTSCWSESPDDRPVFS
... .    ..|..||| |.| ..  |..|.||||.|..|||... ||.||||.  . |....  |||.. |. ..|. ..| ||..||  .|..|| | 
YYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFE

DLVSSI
|||. .
DLVQQM

Kinase AqueK369.AA Met 138-300 42 7.8e-67 218.06 In-house 104-271 (271) Show / Hide
Range on Protein: 138-300
Range on HMM: 104-271/271
Sequence Identity: 42% (75 aa)

KQLLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDI-YAKNYFRQFKRNTNESPSLTT-VKLPVKWMAIESLH--------DGL-
..|.. |.||| || |.|||.|.|||||.||||.|   ..|||||||. |. | | |  |  .        |   .||||||| |.|         .   
RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHH--------THPARLPVKWMAPECLQQGVCLGCPTYRQ

FSEKTDVWSYGILCWEVFSLGRVPYPGLDP-VGVVEFLDTG--GRLLAPRGEACSKEIY-SLMTSCWSESPDDRPVFS
|. |.|||| |.. || .  | .|||  |. . .  .| .|   ||. |  | |   .|  .| .||. .| ||| ||
FTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQP--EYCPDHLYTDVMLCCWHANPEDRPQFS

Kinase AqueK369.AA Fer 35-307 28 1e-60 205.52 In-house 1-283 (283) Show / Hide
Range on Protein: 35-307
Range on HMM: 1-283/283
Sequence Identity: 28% (89 aa)

LTIQESVGQGEFGIVYRG------LISVKND-IPQAIAAKTLKGFYSKSD-IDSLLDECIIMMS-FDNLNVLPLIGVCLDLGP----------GSLLSYL
 |...  | | ||.||.|      . ... .  . |.. |..|.  .. . |  .. |  ||.. .|  ||  ..||| |  |          |||.|||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

KKERA-NLTVADTSEEDIVLNVRKQLLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGIIK---VADFGLSED----IYAKN--YFRQFKRNTNESP
||. . ....             .... .|.|.|.|| || |.  ||||.||||| ...... |   ..|||.| .    .|..                
KKNKNKTVSD-------------NEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE------------

SLTTVKLPVKWMAIESLHDGLFSEKTDVWSYGILCWEVFSLGRVPYPG----LDPVGV----VEFLDTGGRLLAPRGEACSKEIYSLMT-SCWSESPDDR
  .  |.|..|.| |.. .|..|.||||||.|..|||.|. |  ||||    . .  |    ..   ..|. . |  . . .||...|. .|| . |.||
--KACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMM-PMPNHMPPEIMQIMMKQCWQKDPEDR

PVFSDLVSSIN
| .....  ..
PTMKEICQKLK

Kinase AqueK369.AA Src 35-306 34 2.9e-60 203.42 In-house 1-255 (255) Show / Hide
Range on Protein: 35-306
Range on HMM: 1-255/255
Sequence Identity: 34% (98 aa)

LTIQESVGQGEFGIVYRGLISVKNDIPQAIAAKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDL----------GPGSLLSYLKKERANLTV
..  .  ||| || |. |.   .. .. |.  ||||      . . .| |  || ...  ... |  || .             |||| ||||       
IKLCRKLGQGQFGEVWMGYW--NGNTKVAV--KTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-------

ADTSEEDIVLNVRKQLLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIY--AKNY-FRQFKRNTNESPSLTTVKLPVKWMAIES
   ..|   |... ||...  |||.||.|| |...|||||||||  ...| . |||||||   |     .|  |.              |.|.||.| | 
---DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARH------------GAKFPIKWTAPEA

LHDGLFSEKTDVWSYGILCWEVFSLGRVPYPGLDPVGVVEFLDTGGRLLAPRGEACSKEIYS-LMTSCWSESPDDRPVFSDLVSSI
.. | |. |.||||.||| .|... ||||||| .   |.. .. | |.  |. . | .|.|  .|. || ..|..|| |  | .  
INYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRM--PCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase AqueK369.AA HMTK 140-305 38 1e-57 198.05 In-house 130-291 (291) Show / Hide
Range on Protein: 140-305
Range on HMM: 130-291/291
Sequence Identity: 38% (65 aa)

LLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIY-AKNYFRQFKRNTNESPSLTTVKLPVKWMAIESLH--DGLFSEKTDVWSY
.|..| |.| || |.||||..|.|||||||.. .| ..|.|||||.  .   ..|... |.       .  ||||.||||.| .   .. ||||.|||..
QLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRKH-------M--VKLPIKWMAPEAMDGKRKIFSEKSDVWAF

GILCWEVFSLGRVPYP--GLDPVGVVEFLDTGGRLLAPRGEACSKEIYSLMTSCWSESPDDRPVFSDLVSS
|...||... |..||.  ..    |   .  |.||  |   .|..... ||..||   |. || |..|  .
GVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM

Kinase AqueK369.AA ALK 140-308 45 1.8e-57 196.97 In-house 113-273 (273) Show / Hide
Range on Protein: 140-308
Range on HMM: 113-273/273
Sequence Identity: 45% (78 aa)

LLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNG---IIKVADFGLSEDI-YAKNYFRQFKRNTNESPSLTTVKLPVKWMAIESLHDGLFSEKTDVWS
|| .|. || |  || ...||||| |||||     |   . |.|||| . || |   |.|   |            .|||||  | . ||.|  ||||||
LLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRKGGRAM----------MPVKWMPPEAFMDGIFTSKTDVWS

YGILCWEVFSLGRVPYPGLDPVGVVEFLDTGGRLLAPRGEACSKEIYSLMTSCWSESPDDRPVFSDLVSSINA
.|.||||.||||..||||     | ||. .|||.  ||.  |   .| .|| ||   | ||| | ... .| .
FGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY

Kinase AqueK369.AA Axl 140-304 44 4.9e-54 185.83 In-house 115-267 (267) Show / Hide
Range on Protein: 140-304
Range on HMM: 115-267/267
Sequence Identity: 44% (73 aa)

LLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYAKNYFRQFKRNTNESPSLTTVKLPVKWMAIESLHDGLFSEKTDVWSYGIL
|.   . .| || ||....||||||||||||. ..  . |||||||  ||.  |.|| .            |.||||.||||| | ..  | |||..|. 
LVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGC----------IAKMPVKWIAIESLADRVYTSKSDVWAFGVT

CWEVFSLGRVPYPGLDPVGVVEFLDTGGRLLAPRGEACSKEIYSLMTSCWSESPDDRPVFSDLVS
 ||.   |. ||||..   . ..|  | ||  |  | |  |.| || .||.  | ||| || |  
MWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQP--EDCMDELYDLMYQCWEADPKDRPSFSVLRE

Kinase AqueK369.AA Pkinase_Tyr 35-193 34 2.3e-53 181.37 Pfam 1-166 (270) Show / Hide
Range on Protein: 35-193
Range on HMM: 1-166/270
Sequence Identity: 34% (60 aa)

LTIQESVGQGEFGIVYRGLIS-VKNDIPQAIAAKTLKGFYSKSD--IDSLLDECIIMMSF-DNLNVLPLIGVCL-DLGP------------GSLLSYLKK
.|. .  |.|.|| ||.|     . .  .  | |.||  .....  ..... |  ||... .. |.. |.|||. . .|            |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERANLTVADTSEEDIVLNVRKQLLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYAKNY
 |         |..  |..   ||..|.|.|.|| ||.|...||||||||||....|...|..||||. ||| . |
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDY

Kinase AqueK369.AA Pkinase_Tyr 211-306 44 3.1e-48 163.98 Pfam 175-270 (270) Show / Hide
Range on Protein: 211-306
Range on HMM: 175-270/270
Sequence Identity: 44% (44 aa)

KLPVKWMAIESLHDGLFSEKTDVWSYGILCWEVFSLGRVP-YPGLDPVGVVEFL-DTGGRLLAPRGEACSKEIYSLMTSCWSESPDDRPVFSDLVSSI
|||.|||| |....| |..|.||||.|.|.||.|..|. | |||...  |.|.. . |.|. .|..  |..|||.||..|| . |.||| ||.... .
KLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase AqueK369.AA Tec 211-308 43 8.6e-35 119.02 In-house 159-254 (254) Show / Hide
Range on Protein: 211-308
Range on HMM: 159-254/254
Sequence Identity: 43% (43 aa)

KLPVKWMAIESLHDGLFSEKTDVWSYGILCWEVFSLGRVPYPGLDPVGVVEFLDTGGRLLAPRGEACSKEIYSLMTSCWSESPDDRPVFSDLVSSINA
| |||| . | .|   .| | |||..|.| |||||.|..||. .. . |||   .| ||  |.   ||..||  | .||.|.|..|| |..| ..|  
KFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPH--LCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE

Kinase AqueK369.AA Tec 109-185 37 3.8e-24 81.31 In-house 79-144 (254) Show / Hide
Range on Protein: 109-185
Range on HMM: 79-144/254
Sequence Identity: 37% (30 aa)

GSLLSYLKKERANLTVADTSEEDIVLNVRKQ--LLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGIIKVADFGLS
|.||.||....  .              ...  ||..|..|  || || .. ||||||||||| ..|....||.|||..
GCLLNYLREHKHHFQ-------------KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMT

Kinase AqueK369.AA S_TKc 35-310 19 7.3e-21 76.55 SMART 1-231 (231) Show / Hide
Range on Protein: 35-310
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

LTIQESVGQGEFGIVYRGLISVKNDIPQAIAAKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCL--------DLGPG---SLLSYLKKERAN--
 .| . .|.| || ||..         .  | | .|        .... |  |... .  |.  |..|.         .. .|   .|..|.|| . .  
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTVADTSEEDIVLNVRKQLLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYAKNYFRQFKRNTNESPSLTTVKLPVKWMA
   ..  ..              ... |..... |. |...|||||   | ..|.   ||..||||.  .                   ||.     .||
RFPFPE-HAR-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------TTFCGTPWYMA

IESLHDGLFSE-KTDVWSYGILCWEVFSLGRVPYPGLDPVGVVEFLDTGGRLLAPRGEACSKEIYSLMTSCWSESPDDRPVFSDLVSSI-----NALI
 | |    ..  | |.|| |.. .| .. |. |.|      . . ..  |          |.|  ...  |.   |..||   ..  .         .
PEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK369.AA Pkinase 138-306 21 4.8e-19 68.43 Pfam 108-293 (293) Show / Hide
Range on Protein: 138-306
Range on HMM: 108-293/293
Sequence Identity: 21% (44 aa)

KQLLSICLQVANGMCYLASQRFIHRDLAARNCMIDDNGII----KVADFGLSEDIYAKNYFRQFKRNTNESPSLTTVKLPVKWMAIESLH-DGLFSEKTD
... ....|.. |. |. |...|||||   |..||.|| |    |..||||.. ..           .  .. .||.     .|| | .  .   . | |
WECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VWSYGILCWEVFSLGRVPYPGL----DPVGVVEFLDTGGR--LLAPRGEACS-------------------KEIYSLMTSCWSESPDDRPVFSDLVSS--
.||.|....|... || |.||     . .   . ..  ..  |  .. . ||                   .|  .....|.   | .|| . ... .  
MWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

I
.
F

Kinase AqueK369.AA Met 36-105 37 4.8e-11 32.16 In-house 1-72 (271) Show / Hide
Range on Protein: 36-105
Range on HMM: 1-72/271
Sequence Identity: 37% (27 aa)

TIQESVGQGEFGIVYRGLISVKNDIPQAIAAKTLK--GFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLD
   . .||| || ||.|  . .      .| |.|.         |   | | |.|  ||  ||| |||.|||
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLD

Kinase AqueK369.AA Axl 35-106 32 3.6e-10 31.99 In-house 1-73 (267) Show / Hide
Range on Protein: 35-106
Range on HMM: 1-73/267
Sequence Identity: 32% (24 aa)

LTIQESVGQGEFGIVYRGLISVKNDIPQAIAAKTLK-GFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDL
...   .|.|||| |  | .       . .| |..|    ..|.|.  | | . |  ||  ||. |||||. .
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQM

Kinase AqueK369.AA ALK 35-108 35 2.5e-09 28.37 In-house 1-76 (273) Show / Hide
Range on Protein: 35-108
Range on HMM: 1-76/273
Sequence Identity: 35% (27 aa)

LTIQESVGQGEFGIVYRGLISV-KND-IPQAIAAKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGP
.|     |.| || || |. |   .|  | ..| |||.   |. |    . |  ||  |.  ||  .||.|..  |
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQP

Kinase AqueK369.AA HMTK 35-104 24 0.008544 5.69 In-house 1-94 (291) Show / Hide
Range on Protein: 35-104
Range on HMM: 1-94/291
Sequence Identity: 24% (23 aa)

LTIQESVGQGEFG-----------------IVYRGLIS-------VKNDIPQAIAAKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCL
|. .   |.| ||                  || .. |        . . |.  | |.|.|  |  |..  | |.. |  ..  |.. |.|||.
LKAIKVIGAGQFGMVQCLRLAPPDEGCTSLKVYLAEWSVKDGDGKDDSNQPHHRAVKMLRGDASHEDREEFLREAEVMCQLRHPNLVQLVGVCM

Kinase AqueK369.AA Tec 35-52 44 0.038328 3.38 In-house 1-18 (254) Show / Hide
Range on Protein: 35-52
Range on HMM: 1-18/254
Sequence Identity: 44% (8 aa)

LTIQESVGQGEFGIVYRG
||. . .|.| ||.| .|
LTFMKELGSGQFGVVHLG

Kinase AqueK369.AA Pkinase 35-52 38 0.054435 8.12 Pfam 1-18 (293) Show / Hide
Range on Protein: 35-52
Range on HMM: 1-18/293
Sequence Identity: 38% (7 aa)

LTIQESVGQGEFGIVYRG
..| . .|.| || ||..
YHIGRKIGSGSFGCVYKC