Gene AqueK367 (A.queenslandica)

AqueK367

Species: A.queenslandica
Alias: AqueK367
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK367.AA Protein None 708 None Fasta, JSON
AqueK367.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of AqueK367.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NIDO AqueK367.AA NIDO 48-205 31 7.2e-46 159.62 SMART 1-185 (185) Show / Hide 
Range on Protein: 48-205
Range on HMM: 1-185/185
Sequence Identity: 31% (58 aa)

PFWADVDT---RNGAGTVYFRE----TTDCAIMSKVAQDVQLAFPEQL--SFTATSVVIVTWYRVGYFNLNS----------DELNTFQCVLAT--DGSR
|||.|.|.     | | .|.||    |.| .|... ...|. .|...   .|.|..|.||||..|.... ..          ...||||.||||  |.|.
PFWQDADQSYACHGRGNIYYREDSTFTMDHWILDRAMRWVRYQFTDMWDDWFRAKWVFIVTWENVQHYGAQWSKDAPFDHREGWTNTFQAVLATDSDESM

SYVLFLYLDDGINWITGDASGGVDGFN--GTEAYVGFNSGGPNSTY-----FAVEGSGTPEVVDIETTSNV-DVEGLWIFQVSGDNI
.|..|.| ..| .|  ....|. |..   |. |..|||.|    ..     .   .||.|.. ... .|||  . | |.|.|.|. |
TYAIFNYPRLGWQW--HTTQGKDDRNGMGGVPAQAGFNGGDGTFWWEVDNFYTLPQSGEPNIWNLNENSNVHGIPGRWMFRVDGREI
NIDO AqueK367.AA NIDO 113-203 44 1.6e-34 125.45 Pfam 1-96 (96) Show / Hide 
Range on Protein: 113-203
Range on HMM: 1-96/96
Sequence Identity: 44% (43 aa)

LNTFQCVLATDGSRSYVLFLYLDDGINWITGDASGG--VDGFNGTEAYVGFNSGGP--NSTYFAV-EGSGTPEVVDIETTSNVDVEGLWIFQVSGD
 ||||.|||||||.....|.| .|||.|.||..|||    | .|. |..|||.|     . || .  ||.|..|.....|||| . |.|.|...| 
TNTFQAVLATDGSDTFAIFNYPEDGIQWTTGTHSGGDSWNGLGGVPAQAGFNRGDGYFENRYFMLQPGSRTEDVRNLYQTSNVGQPGRWMFHIDGR
CCP AqueK367.AA CCP 210-265 23 7.9e-14 53.18 SMART 1-79 (79) Show / Hide 
Range on Protein: 210-265
Range on HMM: 1-79/79
Sequence Identity: 23% (19 aa)

CGIPD---QLNVNETILSY--------NSTFINSTATYSCEDGYSLVG-----------DAVRTCLSSGKWSGNP----PDC
|. |.   ..   . . |         ... ...|.||||..||.|.|            ...||...  ||. |    | |
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi AqueK367.AA Sushi 210-265 22 1.4e-13 51.11 Pfam 1-65 (65) Show / Hide 
Range on Protein: 210-265
Range on HMM: 1-65/65
Sequence Identity: 22% (15 aa)

CG-IPDQ--LNVN-ETILSY-----NSTFINSTATYSCEDGYSLVGD--AVRTCLSSGKWSGNPPD-C
|. .| .  .. . .          | ....|...|.|..|| ..|.  ...||  .| |.. .|. |
CPFDPPDPNIPHGHVIHTTKWRCYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTPC
CCP AqueK367.AA CCP 271-327 25 1.2e-13 52.53 SMART 1-79 (79) Show / Hide 
Range on Protein: 271-327
Range on HMM: 1-79/79
Sequence Identity: 25% (21 aa)

CSELM---VEPNEGLSVSY-------SSNTPYNITVTYSCEDGYSLVG-----------VTVRTCLSSGNWSGNP----PYC
|. .    . .|  ...|          ...|. ||||||..||.|.|            ...||...  ||. |    | |
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi AqueK367.AA Sushi 271-327 20 8.4e-09 34.11 Pfam 1-65 (65) Show / Hide 
Range on Protein: 271-327
Range on HMM: 1-65/65
Sequence Identity: 20% (14 aa)

CS----ELMVEPNEGLSVSYS------SNTPYNITVTYSCEDGYSLVGV--TVRTCLSSGNWSGNPPY-C
|.    ..   .. |.....       . .... .|.|.|..|| ..|    ..||  .| |.. .|  |
CPFDPPDP-N-IPHGHVIHTTKWRCYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTPC
CCP AqueK367.AA CCP 332-389 25 1.3e-11 45.78 SMART 1-79 (79) Show / Hide 
Range on Protein: 332-389
Range on HMM: 1-79/79
Sequence Identity: 25% (21 aa)

CSELM---VESNEGLSVSYSS------NTKHYNSTATYSCEDGYSLVG-----------DAGRTCLSSGNWSGDT----PYC
|. .    .  |  ...| |.      .| .|..|.||||..||.|.|            . .||...  ||. .    | |
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi AqueK367.AA Sushi 332-389 22 3.1e-09 35.65 Pfam 1-65 (65) Show / Hide 
Range on Protein: 332-389
Range on HMM: 1-65/65
Sequence Identity: 22% (16 aa)

CS----ELMVESNEGLSVSYSS-----NTKHYNSTATYSCEDGYSLVGD--AGRTCLSSGNWSGD--TPYC
|.    ..    . |.....       |   ..|...|.|..|| ..|.  . .||  .| |..   || |
CPFDPPDP-N-IPHGHVIHTTKWRCYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTP-C
TyrKc AqueK367.AA TyrKc 429-682 32 5e-87 296.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 429-682
Range on HMM: 1-280/280
Sequence Identity: 32% (97 aa)

LKIQETVGRGEFGIVYRGLISVKNDIPQAIAAKTLRSFYSKSDIDSLLDECIIMMSF--DNLNVLPLIGVCLDLG------PAPYIIMPFMSRGSLLSYL
..  .. |.|.||.||.|  .      .  | |.|..      .  ...|  ||...  .. |.. |.|||.. |      . ..|.| .|. |.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERPNLTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNC----------------IQLEDD--------NNSS----PVK--LPL
.| ||.            |.. |.|||.|.|. .|| ||.|...||||||||||                  ..||          ..      |  ||.
RKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

KWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPG-----LDPMGIVELLNTGGRLHTPNNEA------CSNEIYSLMNSCWSESPDDRPVFSDLV
.|||.|.| .| |..||||||.||..||.|..|  ||||     ...  ..|.. .|.|.  | |        |. |.|..| .|| | |.||| ||...
RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH

SSI
. .
ECF
Pkinase_Tyr AqueK367.AA Pkinase_Tyr 429-574 34 1.1e-48 165.54 Pfam 1-142 (270) Show / Hide 
Range on Protein: 429-574
Range on HMM: 1-142/270
Sequence Identity: 34% (52 aa)

LKIQETVGRGEFGIVYRGLIS-VKNDIPQAIAAKTLRSFYSKSD--IDSLLDECIIMMSF-DNLNVLPLIGVCLDLGPA--PYIIMPFMSRGSLLSYLKK
... .. |.|.|| ||.|     . .  .  | |.|.  .....  ..... |  ||... .. |.. |.|||.| |    .||.|..|  |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERPNLTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNC
 |         |..  |..   ||..|.|. .|| ||.|...||||||||||
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNC
Kinase AqueK367.AA Pkinase_Tyr 587-682 47 3.7e-47 160.34 Pfam 175-270 (270) Show / Hide 
Range on Protein: 587-682
Range on HMM: 175-270/270
Sequence Identity: 47% (47 aa)

KLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVP-YPGLDPMGIVELL-NTGGRLHTPNNEACSNEIYSLMNSCWSESPDDRPVFSDLVSSI
||| ||||.|.|..| |..||||||.|||.||.|..|. | |||...  ..|..   |.|.  | |  |. |||.|| .|| . |.||| ||.... .
KLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK367.AA KIN6 587-682 47 9.8e-45 145.64 In-house 210-305 (305) Show / Hide 
Range on Protein: 587-682
Range on HMM: 210-305/305
Sequence Identity: 47% (47 aa)

K-LPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLD-PMGIVELLNTGGRLHTPNNEACSNEIYSLMNSCWSESPDDRPVFSDLVSSI
. ||.||||.|..    || ||||||.||| .|.|||| ||||..  |  . | .  |.|.  | .  |..|||  | |||.| ||||| |...   .
RYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW--CPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase AqueK367.AA TK 587-682 31 3.4e-43 142.18 In-house 346-486 (486) Show / Hide 
Range on Protein: 587-682
Range on HMM: 346-486/486
Sequence Identity: 31% (45 aa)

KLPLKWMALESIHDGL---------FSEKSDVWSYGVLCWEVFSLGRVPYPG-LDP---------MGIVELLNTGGR------------LHTPNNEACS-
|||..||| |.. |.          |..||||||.|||.||.|..|..||.| ..            ..|.| .|||            .  |  . |. 
KLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPD

-------------NEIYSLMNSCWSESPDDRPVFSDLVSSI
              |.| || .||.. |.||| ||.|.. .
WMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK367.AA TK-Unique 580-682 41 3.4e-40 136.34 In-house 190-294 (294) Show / Hide 
Range on Protein: 580-682
Range on HMM: 190-294/294
Sequence Identity: 41% (44 aa)

DNNSSPVKLPLKWMALESIH--DGLF-SEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEAC-SNEIYSLMNSCWSESPDDRPVF
... |  ..|..|||.||.   .| . ..||||||.||| ||.|.||  ||||...  |.|..  | |.  |..  | |.|.|.|| |||...|..|| |
SMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSF

SDLVSSI
..... .
RQIKHRL
Kinase AqueK367.AA UTK 587-682 42 6.9e-40 134.14 In-house 200-296 (296) Show / Hide 
Range on Protein: 587-682
Range on HMM: 200-296/296
Sequence Identity: 42% (41 aa)

KLPLKWMALESIHDG-LFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEACSNEIYSLMNSCWSESPDDRPVFSDLVSSI
..|..||| |.. ..  |..||||||.||.|||... ||.||||.  | ... .  |||.. | ...|. ..| ||..||  .|..|| | |||. .
RWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK367.AA TK 429-574 18 2.6e-39 128.9 In-house 1-271 (486) Show / Hide 
Range on Protein: 429-574
Range on HMM: 1-271/486
Sequence Identity: 18% (50 aa)

LKIQETVGRGEFG---IVYRGLISV----------------------KNDIPQAIAAKTLRSFYSKSDIDSLL---------------DECIIMMS---F
... .. |.|.||    ||.|.                         |.. ..  | |.|..  . |. . ..                | . ||.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNLNVLPLIGVCLDLG-----------PAPYIIMPFMSRGS----LLSYLKKERP-----------------------------NLTVADTSEEDIILNV
.  |.. |.|||.. .           . ..|.| .|. |.    |..||.| ||                             ..  .. .... . . 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY-SHESNSPC-PEEQ

---------------RKQLLS-------------------ICLQVGNGMCYLASQ------KFIHRDLAARNC
                |.||.                   .|.|. .|| ||.|.      .|.|||||||||
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNC
Kinase AqueK367.AA ALK 588-684 45 9.9e-38 127.81 In-house 179-273 (273) Show / Hide 
Range on Protein: 588-684
Range on HMM: 179-273/273
Sequence Identity: 45% (44 aa)

LPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEACSNEIYSLMNSCWSESPDDRPVFSDLVSSINA
.| |||  |   ||.|  |.||||.||||||.||||..||||     . |.. .|||.  | |  |   .| .|  ||   | ||| | ... .| .
MPVKWMPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase AqueK367.AA Met 430-574 35 3.2e-37 119.4 In-house 1-135 (271) Show / Hide 
Range on Protein: 430-574
Range on HMM: 1-135/271
Sequence Identity: 35% (53 aa)

KIQETVGRGEFGIVYRGLISVKNDIPQAIAAKTLR--SFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGP-APYIIMPFMSRGSLLSYLKKERPN
   . .|.| || ||.|  . .      .| |.|          |   | | |.|  ||  ||| |||.|||     |... |.|  | |... . .  |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNC
..|             ..|.. |.||  || |.|||||.|||||.|||
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNC
Kinase AqueK367.AA FGFR 588-682 43 7.1e-37 123.18 In-house 200-293 (293) Show / Hide 
Range on Protein: 588-682
Range on HMM: 200-293/293
Sequence Identity: 43% (42 aa)

LPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLD-PMGIVELLNTGGRLHTPNNEACSNEIYSLMNSCWSESPDDRPVFSDLVSSI
|| ||||.|.  |  .  .||||||||| ||.. .|  |||.      . ..| .| |.  | |  ||.||| .| .|| ..|..|| |  || ..
LPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase AqueK367.AA Tec 577-684 43 5.3e-35 119.77 In-house 148-254 (254) Show / Hide 
Range on Protein: 577-684
Range on HMM: 148-254/254
Sequence Identity: 43% (47 aa)

LEDDNNSSP-VKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEACSNEIYSLMNSCWSESPDDRPVF
| |.  ||   | | || . |  |   .| |||||..||| |||||.|..||. .. . .||   .| ||. |  . ||..||  |..||.|.|..|| |
LDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRP--HLCSMHIYQIMYHCWHEKPEERPTF

SDLVSSINA
..| ..|  
QQLLRQITE
Kinase AqueK367.AA Src 587-682 41 2.7e-34 113.9 In-house 161-255 (255) Show / Hide 
Range on Protein: 587-682
Range on HMM: 161-255/255
Sequence Identity: 41% (40 aa)

KLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEACSNEIYS-LMNSCWSESPDDRPVFSDLVSSI
|.| ||.| | |. | |. ||||||.|.| .|... ||||||| . .  .. .  | |.  | |  |  |.|  .|  || ..|..|| |  | .  
KFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK367.AA TK-Unique 429-574 28 1.4e-33 113.23 In-house 1-164 (294) Show / Hide 
Range on Protein: 429-574
Range on HMM: 1-164/294
Sequence Identity: 28% (47 aa)

LKIQETVGRGEFGIVYRGLISVKN---DIPQAIAAKTLRSFYSKSDIDSLLDECIIMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
|......|.|.|| |.|| .. ..   | .. .| |.|.   .. | . .|.|  .|.. .   |.. ..|.| . .  ..|||.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

P---------NLT-VADTSEEDIILN-VR-KQLLSICLQVGNGMCYLAS--QKFIHRDLAARNC
|         ||   ... ...  .. .  |.|.... |. .|| ||||  .|..||||.|||.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNV
Kinase AqueK367.AA Met 585-676 40 3.4e-32 102.63 In-house 169-271 (271) Show / Hide 
Range on Protein: 585-676
Range on HMM: 169-271/271
Sequence Identity: 40% (42 aa)

PVKLPLKWMALESIH--------DGL-FSEKSDVWSYGVLCWEVFSLGRVPYPGLDP-MGIVELLNTG--GRLHTPNNEACSNEIY-SLMNSCWSESPDD
| .||.||||.|.          .   |. |||||| ||. || .  | .|||  |.   |   | .|   ||  |  | |   .|  .| .||. .| |
PARLPVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQP--EYCPDHLYTDVMLCCWHANPED

RPVFS
|| ||
RPQFS
Kinase AqueK367.AA UTK 429-574 28 3.8e-32 107.28 In-house 1-149 (296) Show / Hide 
Range on Protein: 429-574
Range on HMM: 1-149/296
Sequence Identity: 28% (45 aa)

LKIQETVGRGEFGIVYRGLI-SVKNDIPQAIAAKTLRSFYSKSD----ID---SLLDECI---IMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSL
... .. |.|.||.|...    ...  .... | . ..  ...|     .    .. |.    .|. |.   ||| |.|||.. .| ..|.. .|..|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ--HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDL

LSYLKKERPNLTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNC
.||| . ||..      ... .|. . |.|. .... .|| ||.|..|.|||||||||
RSYLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNC
Kinase AqueK367.AA Axl 587-680 44 8.6e-31 106.19 In-house 176-267 (267) Show / Hide 
Range on Protein: 587-680
Range on HMM: 176-267/267
Sequence Identity: 44% (42 aa)

KLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEACSNEIYSLMNSCWSESPDDRPVFSDLVS
|.| ||.|.||. | ..  |||||..||  ||.   |. ||||..   . . |  | ||  |  | | .|.| || .||.  | ||| || |  
KMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQP--EDCMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase AqueK367.AA Axl 429-579 33 4.6e-24 81.99 In-house 1-149 (267) Show / Hide 
Range on Protein: 429-579
Range on HMM: 1-149/267
Sequence Identity: 33% (52 aa)

LKIQETVGRGEFGIVYRGLISVKNDIPQAIAAKTLR-SFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLG-----PAPYIIMPFMSRGSLLSYLKK
. .  ..|.|||| |  | .       . .| |...    ..|.|.  | | . |  ||  ||. |||||. .      |.| .|.|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ERPNLTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNCIQLED
 |         .. . | . . |.   . .  || ||....|||||||||||.  ||
SR-------LGDQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLRED
Kinase AqueK367.AA Src 429-573 35 8e-24 77.78 In-house 1-127 (255) Show / Hide 
Range on Protein: 429-573
Range on HMM: 1-127/255
Sequence Identity: 35% (51 aa)

LKIQETVGRGEFGIVYRGLISVKNDIPQAIAAKTLRSFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLT
.|  .  |.| || |. |.   .. .. |.  |||..     . . .| |  || ...  ... |  || .  |  ||.  .||.|||| ||||      
IKLCRKLGQGQFGEVWMGYW--NGNTKVAV--KTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKK------

VADTSEEDIILNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARN
    ..|   |... ||...  || .||.|| |...|||||||||
----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARN
Kinase AqueK367.AA ALK 429-574 34 1.7e-23 77.94 In-house 1-142 (273) Show / Hide 
Range on Protein: 429-574
Range on HMM: 1-142/273
Sequence Identity: 34% (52 aa)

LKIQETVGRGEFGIVYRGLISV-KND-IPQAIAAKTLRSFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPN
..     |.| || || |. |   .|  | ..| |||.   |. |    . |  ||  |.  ||  .||.|..  |  .|.  .|. | ..|.|.  ||.
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH

LTVADTSEE--DIILNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNC
       .|     . . | || .|. |  |  || ...||||| |||||
-------PESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNC
Kinase AqueK367.AA Tec 495-574 37 1.3e-19 65.3 In-house 61-128 (254) Show / Hide 
Range on Protein: 495-574
Range on HMM: 61-128/254
Sequence Identity: 37% (31 aa)

GVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLTVADTSEEDIILNVRKQ--LLSICLQVGNGMCYLASQKFIHRDLAARNC
|||.   |  ||.  .|..|.||.||....  .              ...  ||..|..|  || || ...|||||||||||
GVCSQQRPI-YIVTEYMEHGCLLNYLREHKHHFQ-------------KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNC
Kinase AqueK367.AA FGFR 429-573 28 3.2e-19 62.12 In-house 1-166 (293) Show / Hide 
Range on Protein: 429-573
Range on HMM: 1-166/293
Sequence Identity: 28% (48 aa)

LKIQETVGRGEFGIVYRGLIS--VKN--DIPQAIAAKTLRSFYSKSDIDSLLDECIIM-MSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKE
| . .. | | || | ..     ...  .   ..| | | .  .  |. .|  |  .| |   . |.. |.|.|   || .|.|  . ..| |  .|.. 
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGP-LYVIVEYCHHGNLRDFLRAR

RPNLTVADTSEE-------DIILNV----------RKQLLSICLQVGNGMCYLASQKFIHRDLAARN
||    .. . .        .   .           |.| |.  ||  || ||||.| |||||||||
RPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARN
Kinase AqueK367.AA S_TKc 429-686 17 4.8e-16 58.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 429-686
Range on HMM: 1-231/231
Sequence Identity: 17% (51 aa)

LKIQETVGRGEFGIVYRGLISVKNDIPQAIAAKTLRSFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSR--GSLLSYLKKERPN
 .| ...|.| || ||..         .  | | ..        .... |  |... .  |.  |..|. |     |..| ...   |.|..|.|| ...
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARN--------------CIQLEDDNNSSPVKLPLKWMALESIHDGLFSE-K
     ..  ..              ... |. ... |. |...|||||   |              . ||      . .   . .|| | .    ..  |
GLRFPFPE-HAR-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCK

SDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEACSNEIYSLMNSCWSESPDDRPVFSDLVSSI-----NALI
.|.|| |.. .| .. |. |.|  ... . ...              | |  .... |.   |..||   ..  .         .
CDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK367.AA KIN6 543-573 54 4.8e-13 39.24 In-house 144-174 (305) Show / Hide 
Range on Protein: 543-573
Range on HMM: 144-174/305
Sequence Identity: 54% (17 aa)

KQLLSICLQVGNGMCYLASQKFIHRDLAARN
|.|...  |. .|| ||.|  .|||||||||
KDLYMFAWQICDGMEYLHSKNCIHRDLAARN
Kinase AqueK367.AA Pkinase 604-682 21 8.6e-09 32.16 Pfam 190-293 (293) Show / Hide 
Range on Protein: 604-682
Range on HMM: 190-293/293
Sequence Identity: 21% (23 aa)

SEKSDVWSYGVLCWEVFSLGRVPYPGL------DPMGIVELLNTGGRLHTPNNEACS-------------------NEIYSLMNSCWSESPDDRPVFSDL
. |.|.||.|....|... || |.||       |.| ... .. |..|| .  . ||                    |  .....|.   | .|| . ..
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMIC-RIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

VSS--I
. .  .
LQHPWF
Kinase AqueK367.AA Pkinase 429-569 21 1.1e-08 31.74 Pfam 1-134 (293) Show / Hide 
Range on Protein: 429-569
Range on HMM: 1-134/293
Sequence Identity: 21% (32 aa)

LKIQETVGRGEFGIVYRGLISVKNDIPQAIAAKTLRSFYSKSDID--SLL-DECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRG----SLLSYLK
..| ...|.| || ||..   .. . ..  | |...    ||. |   ..  |. || ...  |.. |.... | .. .|..|...  |    .| .|..
YHIGRKIGSGSFGCVYKC---HHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

KERPNLTVADTSEEDIIL--NVRKQLLSICLQVGNGMCYLASQKFIHRDL
            ...  .     ... ....|.  |. |. |...|||||
T-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDL
Kinase AqueK367.AA Tec 429-446 38 0.053049 2.88 In-house 1-18 (254) Show / Hide 
Range on Protein: 429-446
Range on HMM: 1-18/254
Sequence Identity: 38% (7 aa)

LKIQETVGRGEFGIVYRG
|.. . .|.| ||.| .|
LTFMKELGSGQFGVVHLG