Gene AqueK362 (A.queenslandica)

AqueK362

Species: A.queenslandica
Alias: AqueK362
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK362.AA Protein None 848 None Fasta, JSON
AqueK362.kin_dom Protein Kinase Domain None 209 None Fasta, JSON

Protein domain

Protein domains of AqueK362.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK362.AA Eph 16-51 37 2.8e-10 30.6 In-house 1-40 (264) Show / Hide 
Range on Protein: 16-51
Range on HMM: 1-40/264
Sequence Identity: 37% (15 aa)

IQIQETVGQGEFGIVYRGVMTSN-PQLPK---AVAVKTLK
|.|.. .| |||| |..| .  . ..  .   .||.||||
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLK
Kinase AqueK362.AA Met 17-52 36 1e-09 27.73 In-house 1-36 (271) Show / Hide 
Range on Protein: 17-52
Range on HMM: 1-36/271
Sequence Identity: 36% (13 aa)

QIQETVGQGEFGIVYRGVMTSNPQLPKAVAVKTLKG
   . .||| || ||.| .. | ..   .|.|.|.|
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHG
Kinase AqueK362.AA TK 16-56 21 9e-09 24.74 In-house 1-66 (486) Show / Hide 
Range on Protein: 16-56
Range on HMM: 1-66/486
Sequence Identity: 21% (14 aa)

IQIQETVGQGEFG---IVYRGVMTSNP----------------------QLPKAVAVKTLKGSEDT
|.. .. |.|.||    ||.| . . .                      . .  ||||.||   ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAM
Kinase AqueK362.AA Pkinase_Tyr 16-51 37 1.4e-08 29.72 Pfam 1-37 (270) Show / Hide 
Range on Protein: 16-51
Range on HMM: 1-37/270
Sequence Identity: 37% (14 aa)

IQIQETVGQGEFGIVYRGVMT-SNPQLPKAVAVKTLK
|.. .. |.|.|| ||.|... .  .    ||||.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK
Kinase AqueK362.AA TK-Unique 16-51 35 1.3e-07 22.4 In-house 1-39 (294) Show / Hide 
Range on Protein: 16-51
Range on HMM: 1-39/294
Sequence Identity: 35% (14 aa)

IQIQETVGQGEFGIVYRGVMTSNP---QLPKAVAVKTLK
. .....|.|.|| |.|| .....     .| ||||.||
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLK
Kinase AqueK362.AA UTK 16-51 31 6e-07 19.8 In-house 1-38 (296) Show / Hide 
Range on Protein: 16-51
Range on HMM: 1-38/296
Sequence Identity: 31% (12 aa)

IQIQETVGQGEFGIVYRGVMTS-NPQLPK-AVAVKTLK
.|. .. |||.||.|...  |  ... .. .||||...
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ
Kinase AqueK362.AA Ror 16-51 34 8.8e-07 23.36 In-house 1-38 (308) Show / Hide 
Range on Protein: 16-51
Range on HMM: 1-38/308
Sequence Identity: 34% (13 aa)

IQIQETVGQGEFGIVYRGVMTSNP--QLPKAVAVKTLK
..  |  | . || ||.|  ..    . . |||.||.|
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCK
Kinase AqueK362.AA Fer 16-56 27 2e-06 18.12 In-house 1-48 (283) Show / Hide 
Range on Protein: 16-56
Range on HMM: 1-48/283
Sequence Identity: 27% (13 aa)

IQIQETVGQGEFGIVYRG--VMTS--NPQLPK---AVAVKTLKGSEDT
. ...  | | ||.||.|  ...     .. .   ||.||..|.. .|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDAT
Kinase AqueK362.AA SRCR 52-81 40 2e-06 23.55 Pfam 78-112 (112) Show / Hide 
Range on Protein: 52-81
Range on HMM: 78-112/112
Sequence Identity: 40% (14 aa)

GSEDTILQCRHNSFGF--HN--CGHD-ENVGVHCR
|.|... ||.| . |   ||  |.|. | .|| |.
GNETSLWQCPHSPWGWHRHNPMCSHSREDAGVICS
Kinase AqueK362.AA InsR 15-51 34 1.6e-05 14.45 In-house 1-40 (278) Show / Hide 
Range on Protein: 15-51
Range on HMM: 1-40/278
Sequence Identity: 34% (14 aa)

IIQIQETVGQGEFGIVYRG----VMTSNPQLPKAVAVKTLK
|..|.|  ||| || || |    ..  ..    ..|.||..
IVLIRE-CGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVN
Kinase AqueK362.AA Pkinase 16-63 25 8.7e-05 18.0 Pfam 1-45 (293) Show / Hide 
Range on Protein: 16-63
Range on HMM: 1-45/293
Sequence Identity: 25% (12 aa)

IQIQETVGQGEFGIVYRGVMTSNPQLPKAVAVKTLKGSEDTILQCRHN
..| ...|.| || ||...  ....    ||||..| ...   .....
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTH
Kinase AqueK362.AA Src 16-51 44 0.000718 8.98 In-house 1-32 (255) Show / Hide 
Range on Protein: 16-51
Range on HMM: 1-32/255
Sequence Identity: 44% (16 aa)

IQIQETVGQGEFGIVYRGVMTSNPQLPKAVAVKTLK
|.  .  ||| || |. |.   | .    |||||||
IKLCRKLGQGQFGEVWMGYWNGNTK----VAVKTLK
Kinase AqueK362.AA Axl 16-51 33 0.00207 7.68 In-house 1-36 (267) Show / Hide 
Range on Protein: 16-51
Range on HMM: 1-36/267
Sequence Identity: 33% (12 aa)

IQIQETVGQGEFGIVYRGVMTSNPQLPKAVAVKTLK
. .  ..|.|||| |  | .  .      ||||..|
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMK
Kinase AqueK362.AA SR 304-405 42 1e-45 159.08 SMART 1-118 (118) Show / Hide 
Range on Protein: 304-405
Range on HMM: 1-118/118
Sequence Identity: 42% (50 aa)

VRLVDGNSPNVGRLEICING----DWGTVCDDMWTHTNAQVVCRQLGYSTDGAVFLR----GAFFGAGNGFILLDDVVCSGSENTILQCTHLSFGSHN--
||||.||.|. ||.|. .||     ||||||| |. ..|.|||||||...  ..  .    .|.||.|.| |..|.| |.|.|... .|.| ..|.||  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CVH------DQDVSVQCS
| |      ..|..| ||
CSHNHHRNRQEDAGVVCS
Kinase AqueK362.AA SRCR 307-405 42 3.6e-38 130.05 Pfam 1-112 (112) Show / Hide 
Range on Protein: 307-405
Range on HMM: 1-112/112
Sequence Identity: 42% (48 aa)

VDGNSPNVGRLEICI-NGDWGTVCDD-M-WTHTNAQVVCRQLGYSTDGAVF-LRGAF--FG--AGNGFILLDDVVCSGSENTILQCTHLSFGS--HN--C
|.|.||. ||.|..  || |||||||   |. ..|.|||||||.  ...    ..|.  ||  .|.| |..|.| |.|.| .. || | . |   ||  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

VHD-QDVSVQCS
 |. .|..|.||
SHSREDAGVICS
Kinase AqueK362.AA Met 270-298 34 4.4e-05 12.29 In-house 8-36 (271) Show / Hide 
Range on Protein: 270-298
Range on HMM: 8-36/271
Sequence Identity: 34% (10 aa)

KGEFGIVYRGVMTNNTQLPKAVSVKTLKG
.| || ||.| .. | ..   . .|.|.|
QGHFGCVYHGMYHDNDGNEHHCACKSLHG
Kinase AqueK362.AA Eph 271-306 30 0.005046 5.84 In-house 10-49 (264) Show / Hide 
Range on Protein: 271-306
Range on HMM: 10-49/264
Sequence Identity: 30% (12 aa)

GEFGIVYRGVMTNN-TQLPK---AVSVKTLKGCSHGQVRL
|||| |..| .  .  .  .   .| .||||  .  . |.
GEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRW
Kinase AqueK362.AA TK-Unique 270-303 32 0.005185 6.37 In-house 9-45 (294) Show / Hide 
Range on Protein: 270-303
Range on HMM: 9-45/294
Sequence Identity: 32% (12 aa)

KGEFGIVYRGVMTNNT---QLPKAVSVKTLKGCSHGQ
.|.|| |.|| .....     .| | ||.|| .....
EGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDT
Kinase AqueK362.AA TK 270-305 18 0.015915 3.42 In-house 9-69 (486) Show / Hide 
Range on Protein: 270-305
Range on HMM: 9-69/486
Sequence Identity: 18% (11 aa)

KGEFG---IVYRGVMTNN----------------------TQLPKAVSVKTLKGCSHGQVR
.|.||    ||.| . .                       .. .  | ||.||  .. . .
EGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQE
Kinase AqueK362.AA Fer 270-298 30 0.029676 3.61 In-house 9-44 (283) Show / Hide 
Range on Protein: 270-298
Range on HMM: 9-44/283
Sequence Identity: 30% (11 aa)

KGEFGIVYRG--VMTN--NTQLPK---AVSVKTLKG
.| ||.||.|  ...    ... .   || ||..|.
EGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKC
Kinase AqueK362.AA Ror 271-297 34 0.061115 4.07 In-house 10-38 (308) Show / Hide 
Range on Protein: 271-297
Range on HMM: 10-38/308
Sequence Identity: 34% (10 aa)

GEFGIVYRGVMTNNT--QLPKAVSVKTLK
. || ||.|  .     . . || .||.|
CQFGKVYKGHLMGPNFMYHCMAVAIKTCK
Kinase AqueK362.AA UTK 270-297 26 0.141904 1.16 In-house 9-38 (296) Show / Hide 
Range on Protein: 270-297
Range on HMM: 9-38/296
Sequence Identity: 26% (8 aa)

KGEFGIVYRGVMTNNT-QLPK-AVSVKTLK
.|.||.|...  |. . . .. .|.||...
QGAFGEVHKARFTQCSEHMYEMDVAVKVCQ
Kinase AqueK362.AA Pkinase_Tyr 270-297 37 3.82594 1.11 Pfam 9-37 (270) Show / Hide 
Range on Protein: 270-297
Range on HMM: 9-37/270
Sequence Identity: 37% (11 aa)

KGEFGIVYRGVMT-NNTQLPKAVSVKTLK
.|.|| ||.|...    .    | ||.||
EGAFGEVYKGTWKGDPDNTKIPVAVKMLK
Pkinase_Tyr AqueK362.AA Pkinase_Tyr 635-843 38 8.3e-78 264.13 Pfam 1-197 (270) Show / Hide 
Range on Protein: 635-843
Range on HMM: 1-197/270
Sequence Identity: 38% (83 aa)

IEIQETVGQGEFGIVYRGVMT-SNTQSPKAVAVKTLKGFFKESD--IDSLLDECIIMMSF-DNLNVLPLIGVCLDLGPA--PYIIMPFMSRGSLLSYLKK
|.. .. |.|.|| ||.|... .  .    ||||.||    ...  ..... |  ||... .. |.. |.|||.| |    .||.|..|  |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERPNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYACNYF-RQLKGSDNNSESSAVKLPVKWM
 |         |..  |..   ||..|.|.|.||.||.|...||||||||||....|...|..||||. |||   |  |. .|.         |||.|||
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG---------KLPIKWM

ALESLHDGLFSEKSDV
|.|....| |..||||
APECINYGKFTTKSDV
Kinase AqueK362.AA Met 636-843 37 9e-67 217.85 In-house 1-202 (271) Show / Hide 
Range on Protein: 636-843
Range on HMM: 1-202/271
Sequence Identity: 37% (82 aa)

EIQETVGQGEFGIVYRGVMTSNTQSPKAVAVKTLK--GFFKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGP-APYIIMPFMSRGSLLSYLKKERPN
   . .||| || ||.| .. | .    .|.|.|.      .  |   | | |.|  ||  ||| |||.|||     |... |.|  | |... . .  |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDI-YACNYFRQLKGSDNNSESSAVKLPVKWMALES
..|             ..|.. |.||| ||.|.|||.|.|||||.||||.|   ..|||||||. |. |   |  |       ..    .|||||||.|.
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQ------MHHTHPARLPVKWMAPEC

LH--------DGL-FSEKSDV
|         .   |. ||||
LQQGVCLGCPTYRQFTTKSDV
Kinase AqueK362.AA TK 635-843 19 2.2e-64 214.43 In-house 1-377 (486) Show / Hide 
Range on Protein: 635-843
Range on HMM: 1-377/486
Sequence Identity: 19% (78 aa)

IEIQETVGQGEFG---IVYRGVMTSN----------------------TQSPKAVAVKTLKGFFKESDIDSLL---------------DECIIMMS---F
|.. .. |.|.||    ||.| . .                       .. .  ||||.||    .|. . ..                | . ||.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNLNVLPLIGVCLDLG-----------PAPYIIMPFMSRGS----LLSYLKKERP-----------------------------NLTVADTSEEDIILNV
.  |.. |.|||.. .           . ..|.| .|. |.    |..||.| ||                             ..  .. .... . . 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY-SHESNSPC-PEEQ

---------------RKQLLS-------------------ICLQVANGMSYLASQ------RFIHRDLAARNCMIDDNGI-----------IKVADFG--
                |.||.                   .|.|.|.||.||.|.      .|.|||||||||....|..           .|.||||  
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSEDIY--------------------ACNYFRQLKGSDNNSESS----------AVKLPVKWMALESLHDGL---------FSEKSDV
      |. |||                    .              . .            |||..||| |.| |.          |..||||
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFE--------------D-DPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDV
Kinase AqueK362.AA UTK 635-843 29 2.1e-59 201.91 In-house 1-223 (296) Show / Hide 
Range on Protein: 635-843
Range on HMM: 1-223/296
Sequence Identity: 29% (68 aa)

IEIQETVGQGEFGIVYRGVMTSNT-QSPK-AVAVKTLK-GFFKESDID---SLLDECI---IMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLS
... .. |||.||.|...  |  . .... .||||... . ... . .    .. |.    .|. |.   ||| |.|||.. .| ..|.. .|..|.|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLKKERPNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNG-------IIKVADFG---LSEDIYACNYFRQLKGSDNN
|| . ||..      ... .|. . |.|. ....|.||.||.|..|.||||||||| .....       ..|.||||   .| ....   |    .... 
YLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFH-FSNRYWESYY

SESS-AVKLPVKWMALESLHDG-LFSEKSDV
. .. . ..|..||| |.| ..  |..||||
YMAQHQDRWPIRWMAPEALTHHTRFTTKSDV
Kinase AqueK362.AA TK-Unique 635-843 30 3.9e-59 202.53 In-house 1-222 (294) Show / Hide 
Range on Protein: 635-843
Range on HMM: 1-222/294
Sequence Identity: 30% (69 aa)

IEIQETVGQGEFGIVYRGVMTSNT---QSPKAVAVKTLKGFFKESDIDSLLDECIIMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
.|.....|.|.|| |.|| .....     .| ||||.||  . . | . .|.|  .|.. .   |.. ..|.| . .  ..|||.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

P---------NLT-VADTSEEDIILN-VR-KQLLSICLQVANGMSYLAS--QRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYACNYFRQLKGSDNNSE
|         ||   ... ...  .. .  |.|.... |.|.||.||||  ....||||.|||... .....|..|||...|.|.        . .....
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT--------NGVYSMM

SSAVKLPVKWMALESLH--DGLF-SEKSDV
 |  ..|..|||.|||   .| . ..||||
CSQGRIPIRWMAPESLKCYHGMYHTTKSDV
Kinase AqueK362.AA Axl 635-843 38 2.3e-48 167.0 In-house 1-198 (267) Show / Hide 
Range on Protein: 635-843
Range on HMM: 1-198/267
Sequence Identity: 38% (82 aa)

IEIQETVGQGEFGIVYRGVMTSNTQSPKAVAVKTLK-GFFKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLG-----PAPYIIMPFMSRGSLLSYLKK
. .  ..|.|||| |  | .  .  |   ||||..|   . .|.|.  | | . |  ||  ||. |||||. .      |.| .|.|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ERPNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYACNYFRQLKGSDNNSESSAVKLPVKWMA
 |         .. . | . . |.   . .| || ||....||||||||||||. ..  . |||||||  ||.  |.|| .         . |.||||.|
SR-------LGDQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGC---------IAKMPVKWIA

LESLHDGLFSEKSDV
.||| | ..  ||||
IESLADRVYTSKSDV
Kinase AqueK362.AA InsR 635-843 33 1.6e-47 157.63 In-house 1-204 (278) Show / Hide 
Range on Protein: 635-843
Range on HMM: 1-204/278
Sequence Identity: 33% (72 aa)

IEIQETVGQGEFGIVYRG----VMTSNTQSPKAVAVKTLKGFFKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
|..    ||| || || |    ..  .     ..|.||..      .    | |  .|  |.  .|  | |||    |. |..| .| .| | |||   |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPM-YVVMEMMTYGDLKSYLRSRR

PNLTVADTSEEDII----LNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYACNYFRQLKGSDNNSESSAVKLPVKW
|        . ...       . |...   ... ||.|||.  |.|||||.||||... . .|..|||.  |||   | |  ...         .||| |
PEEEF---NNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKG---------MLPVRW

MALESLHDGLFSEKSDV
|| ||| || |. .|||
MAPESLKDGVFTTHSDV
Kinase AqueK362.AA Fer 635-843 30 9.6e-43 143.44 In-house 1-201 (283) Show / Hide 
Range on Protein: 635-843
Range on HMM: 1-201/283
Sequence Identity: 30% (69 aa)

IEIQETVGQGEFGIVYRG--VMTS--NTQSPK---AVAVKTLKGFFKESD-IDSLLDECIIMMS-FDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSY
.....  | | ||.||.|  ...    ... .   ||.||..|. ..  . |  .. |  ||.. .|  ||  ..||| |  |  .|.| |.. |||.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPI-MIVMEFCNGGSLDSY

LKKERP-NLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIK---VADFGLSED----IYACN--YFRQLKGSDNNS
|||.   ....             .... .|.|.|.|| || |.  ||||.||||| ...... |   ..|||.| .    .|.                
LKKNKNKTVSD-------------NEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE-----------

ESSAVKLPVKWMALESLHDGLFSEKSDV
   | |.|..|.| |.. .|..|.|.||
--KACKVPIRWLAPETWQTGIYSPKTDV
Kinase AqueK362.AA Src 635-843 38 4.1e-42 140.84 In-house 1-183 (255) Show / Hide 
Range on Protein: 635-843
Range on HMM: 1-183/255
Sequence Identity: 38% (81 aa)

IEIQETVGQGEFGIVYRGVMTSNTQSPKAVAVKTLKGFFKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLT
|   .  ||| || |. |.   ||.    |||||||      . . .| |  || ...  ... |  || .  |  ||.  .||.|||| ||||      
IKLCRKLGQGQFGEVWMGYWNGNTK----VAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKK------

VADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYACNYFRQLK-GSDNNSESSAVKLPVKWMALESLH
    ..|   |... ||...  |||.||.|| |...|||||||||  ...| . |||||||          | .| . |. . ..  |.|.||.| | ..
----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLA---------RLIKEDDDEYCARHGAKFPIKWTAPEAIN

DGLFSEKSDV
 | |. ||||
YGRFTIKSDV
Kinase AqueK362.AA TyrKc 635-848 26 3.1e-38 134.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 635-848
Range on HMM: 1-280/280
Sequence Identity: 26% (81 aa)

IEIQETVGQGEFGIVYRGVMTSNTQSPKAVAVKTLKGFFKESDIDSLLDECIIMMSF--DNLNVLPLIGVCLDLG------PAPYIIMPFMSRGSLLSYL
|.  .. | |.||.||.|...        ||||.||       .  ...|  ||...  .. |.. |.|||.. |      . ..|.| .|. |.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERPNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYAC-------NYFRQLKGSDNNSESSA
.| ||.            |.. |.|||.|.|.|.||.||.|...||||||||||....|...|..||||| |||          | |. ..       . 
RKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH-------KG

VK--LPVKWMALESLHDGLFSEKSDV--------------------------------------------AT----------------------------
 |  ||..|||.|.. .| |..||||                                            .                             
GKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR

-------KGQ
       .  
PTFSEIHECF
Kinase AqueK362.AA Eph 635-843 31 2.7e-32 105.71 In-house 1-193 (264) Show / Hide 
Range on Protein: 635-843
Range on HMM: 1-193/264
Sequence Identity: 31% (68 aa)

IEIQETVGQGEFGIVYRGVMTSN-TQSPK---AVAVKTLKGFFKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
| |.. .| |||| |..| .  .  .  .   .||.||||    |..    | |  ||  ||  |.. | ||     |.  |.  .|  ||| |.|... 
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPV-MIVTEYMENGSLDSFLRQHD

PNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYACNYFRQLKGSDNNSESSAVKLPVKWMALE
  .||.             ||. .   .| || ||..  ..||||||||  .. | . ||.|||||  .      .  .. .   ...  | |..| | |
GQFTVI-------------QLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVL------EDDPSVEATYTTRGGKIPIRWTAPE

SLHDGLFSEKSDV
 .  . |.  |||
AIAYRKFTSASDV
Kinase AqueK362.AA Ror 752-843 42 3.9e-26 93.16 In-house 122-204 (308) Show / Hide 
Range on Protein: 752-843
Range on HMM: 122-204/308
Sequence Identity: 42% (39 aa)

LSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDIYACNYFRQLKGSDNNSESSAVKLPVKWMALESLHDGLFSEKSDV
| | .|.| || ||.|  |.|||||||||.. .   .|..||||. |||.  | | .         .   .|. ||. |.   | ||| ||.
LHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQ---------HKSWMPIRWMSPEAIMYGKFSEDSDI
Kinase AqueK362.AA Pkinase 635-797 25 4.3e-21 75.68 Pfam 1-160 (293) Show / Hide 
Range on Protein: 635-797
Range on HMM: 1-160/293
Sequence Identity: 25% (45 aa)

IEIQETVGQGEFGIVYRGVMTSNTQSPKAVAVKTLKGFFKESDID--SLL-DECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRG----SLLSYLK
..| ...|.| || ||...  .. .    ||||..|   ..|. |   ..  |. || ...  |.. |.... | .. .|..|...  |    .| .|..
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

KERPNLTVADTSEEDIIL--NVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGII----KVADFGLSE
            ...  .     ... ....|.. |. |. |...|||||   |..||.|| |    |..||||..
T-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK
Kinase AqueK362.AA S_TKc 635-837 18 1e-12 9.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 635-837
Range on HMM: 1-231/231
Sequence Identity: 18% (50 aa)

IEIQETVGQGEFGIVYRGVMTSNTQSPKAVAVKTLKGFFKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSR--GSLLSYLKKERPN
 || ...|.| || ||... ..   . . ||.| .|        .... |  |... .  |.  |..|. |     |..| ...   |.|..|.|| ...
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LTVADTSEEDIILNVRKQLLSICLQVANGMSYLASQRFIHRDLAARNCMIDDNGIIKVADFGLSEDI----------------YAC---------
     ..  ..              ... |..... |. |...|||||   | ..|.   ||..||||.  .                | .         
GLRFPFPE-HAR-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCG

-----------------NYFRQLKGSDNNSESSAVK-----LPVK-----WMALESLH-------DGLF
                   |....       |. .|     . .|     . | | |.       .  |
CILYEMLCGYPPFPQMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK362.AA Ror 635-704 27 8.5e-09 31.39 In-house 1-72 (308) Show / Hide 
Range on Protein: 635-704
Range on HMM: 1-72/308
Sequence Identity: 27% (20 aa)

IEIQETVGQGEFGIVYRGVMTSNT--QSPKAVAVKTLKGFFKESDIDSLLDECIIMMSFDNLNVLPLIGVCL
..  |  | . || ||.|  ..    ... |||.||.|          .  |  .| ...  |.  |.|||.
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCT