Gene AqueK361 (A.queenslandica)
AqueK361
Species: A.queenslandica
Alias: AqueK361
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
AqueK361.AA | Protein | None | 466 | None | Fasta, JSON |
AqueK361.kin_dom | Protein Kinase Domain | None | 208 | None | Fasta, JSON |
Protein domains of AqueK361.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Calx_beta | AqueK361.AA | Calx_beta | 81-183 | 26 | 2.3e-10 | 41.7 | SMART | 1-106 (106) | Show / Hide |
Range on Protein: 81-183 Range on HMM: 1-106/106 Sequence Identity: 26% (29 aa) LTGTDLKPL--LFVTFNSSSYFTTESNGQVLLYIERSNR-LSEVVTVTVKTKSSATTTSPANEN-SDYIPV--NQTIAFSARE-TVKTFFITIINDGVTE .| ..| . .| | .. | .|. |.. . ..|. ... |.|. .| . |.. |||.|. .|. | . | |.|.. | ||.| . | ATVMILDDDHMGTVFFEQPHYTVNENCGEFEVCVVRTGGTARGTVVVPYRTQDGT-----ATAGGSDYEPWDIPGTLTFPPGEGTMKCIRIKIIDDDIYE E-TEYFDVVIE . .|.| |... KRDEHFYVRLS |
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Calx-beta | AqueK361.AA | Calx-beta | 81-183 | 28 | 7.4e-09 | 34.53 | Pfam | 1-109 (109) | Show / Hide |
Range on Protein: 81-183 Range on HMM: 1-109/109 Sequence Identity: 28% (32 aa) LTGTDLKP--LLFVTFNSSSYFT--TESNGQVLLYIERSNR---LSEVVTVTVKTKSSATTTSPANEN--SDYIPVNQT-IAFSARE-TVKTFFITIIND | |.| . . | . | .|. |.| . ..| . |. ||| ..| | |... .||.|.. | . |.. | |.|.. .|||.| ATVTILDDDDAIVIGFEPTHYQVDVNENCGTVEVCVVRMGGAPTLRRTVTVMYRTED-GT----ATAGPGDDYEPTEGTILTFNPDEDTHKCINVTIIDD GVTEETEYFDVVIE . |..| | |.. DIYEGDEHFFVHLS |
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Pkinase_Tyr | AqueK361.AA | Pkinase_Tyr | 244-451 | 36 | 1.5e-64 | 219.29 | Pfam | 1-197 (270) | Show / Hide |
Range on Protein: 244-451 Range on HMM: 1-197/270 Sequence Identity: 36% (79 aa) IQVLEVTGQGEFGIVYRALMTLKSDEMPQVVAIKTLKGLFSKSD--IHSFVEECITMSNF-DDPNILPLFGVSLDLGPA--PCIIMPFMSRGSLLSYLEK |. ... |.|.|| ||.. .. . |. . ||.|.|| .... . .| .| .|... . |||. | || .| | ..|.|..| |.||.|| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK ERPNLTVTDISDKDAVLNVRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGIIKIANFGLTEDIYMECYFNQFTDES-ESSKNVKLPVKWMAI | . . |.. ||..|.|.|||| ||.|....|||||||||...||...||. |||. || . .|. .... |||.|||| HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-------YNDDYYYRKRGGGKLPIKWMAP ESLCHGIFSQKSDV |.. .|.|. |||| ECINYGKFTTKSDV |
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Kinase | AqueK361.AA | Met | 245-451 | 36 | 1e-61 | 200.99 | In-house | 1-202 (271) | Show / Hide |
Range on Protein: 245-451 Range on HMM: 1-202/271 Sequence Identity: 36% (81 aa) QVLEVTGQGEFGIVYRALMTL-KSDEMPQVVAIKTLK--GLFSKSDIHSFVEECITMSNFDDPNILPLFGVSLDLGP-APCIIMPFMSRGSLLSYLEKER ...| ||| || ||.. .. .. | . .|.|.|. | | .| |.|. || ||.| | |..|| | .. |.| | |... . . HFDDVIGQGHFGCVYHGMYHDNDGNEHH--CACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQ PNLTVTDISDKDAVLNVRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGIIKIANFGLTEDI-YMECYFNQFTDESESSKN-VKLPVKWMAIE |..| ..|. |.|||||| |.|||.|||||||.||||.|| ..|.| ||| |. | | | .. .||||||| | NNPCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQ-----MHHTHPARLPVKWMAPE SLC--------HGI-FSQKSDV .| . |. |||| CLQQGVCLGCPTYRQFTTKSDV |
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Kinase | AqueK361.AA | TK | 244-451 | 21 | 5.9e-60 | 199.34 | In-house | 1-377 (486) | Show / Hide |
Range on Protein: 244-451 Range on HMM: 1-377/486 Sequence Identity: 21% (82 aa) IQVLEVTGQGEFG---IVYRALMTLKS---------------------DEMPQVVAIKTLKGL--FSKSDIHS-----------FVEECITMSNFD---- |..... |.|.|| ||.... .. .. .. ||.|.|| |. . . | ||. |. .. ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG -DPNILPLFGVSLDLG-----------PAPCIIMPFMSRGS----LLSYLEKERPNLTVT---------------------------------DISDKDA |||. |.||... . . ..|.| .|. |. |..|| | ||. . . ..... HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD VLNV----------RKQLLC-------------------ICLQVAKGMFYLASQ------HFVHRDLAARNCMIDENGI-----------IKIANFG--- ... |.||. .|.|.|.|| ||.|. .|||||||||||...||.. .||| || YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR -----LTEDIYM-ECYFNQF----------------TDESESSKNVKLPVKWMAIESLC---------HGIFSQKSDV |. ||| . | . .|. .... |||..||| |.| .|.|. |||| QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDV |
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Kinase | AqueK361.AA | UTK | 244-451 | 31 | 9.3e-57 | 192.69 | In-house | 1-223 (296) | Show / Hide |
Range on Protein: 244-451 Range on HMM: 1-223/296 Sequence Identity: 31% (73 aa) IQVLEVTGQGEFGIVYRALMTLKSDEMPQ-VVAIKTLK-GLFSKSDIH---SFVEECI---TMSNFD-DPNILPLFGVSLDLGPAPCIIMPFMSRGSLLS .| .. .|||.||.|..| | |. |.. .||.|... . .. . | ||. |..|. ||.| | || .. .| ..|.. .|..|.|.| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS YLEKERPNLTVTDISDKDAVLNVRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENG-------IIKIANFG---LTEDIY-----MECYFNQFT || . ||.. . .. |. . |.|| ....| || ||.|..||||||||||| ..... ..|||.|| .. ... ... YLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSN---RYWES DESESSKNVKLPVKWMAIESLCHG-IFSQKSDV ... .. . ..|..||| |.|.|. |..|||| YYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDV |
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Kinase | AqueK361.AA | TK-Unique | 244-451 | 32 | 1.6e-49 | 168.92 | In-house | 1-222 (294) | Show / Hide |
Range on Protein: 244-451 Range on HMM: 1-222/294 Sequence Identity: 32% (73 aa) IQVLEVTGQGEFGIVYRALMTL--KSDEMPQVVAIKTLKGLFSKSDIHSFVEECITMSNFD-DPNILPLFGVSLDLGPAPCIIMPFMSRGSLLSYLEKER . |..| |.|.|| |.|. .. |... ...||.|.|| ... | | | |.. . |||. ..|.. . . ..|||.....|.|..|| . | LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR P---------NLTVTDISDKDAVLN--VR-KQLLCICLQVAKGMFYLAS--QHFVHRDLAARNCMIDENGIIKIANFGLTEDIYMECYFNQFTDESESSK | || . ...| ... . |.|. .. |.|.|| |||| ...|||||.|||... |....||..||...|.| .. | . . PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT------NGVYSMMCS NVKLPVKWMAIESLC--HGIF-SQKSDV ..|..||| |||. ||.. . |||| QGRIPIRWMAPESLKCYHGMYHTTKSDV |
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Kinase | AqueK361.AA | Axl | 244-453 | 35 | 8.8e-41 | 141.8 | In-house | 1-200 (267) | Show / Hide |
Range on Protein: 244-453 Range on HMM: 1-200/267 Sequence Identity: 35% (76 aa) IQVLEVTGQGEFGIVYRALMTLKSDE-MPQVVAIKTLK-GLFSKSDIHSFVEECITMSNFDDPNILPLFGVSLDLG-----PAPCIIMPFMSRGSLLSYL . . . |.|||| | . || .. . ||.|..| ...|.| |. | . | .|| ||.. | ||.. . |.| .|.||| | | ..| FVLGKMLGEGEFGSVMEG--QLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFL EKERPNLTVTDISDKDAVLNVRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGIIKIANFGLTEDIYMECYFNQFTDESESSKNVKLPVKWMA | . |. | . . |. . .| || ||....|.||||||||||. |. . .| ||| || |. | . |.||||.| LYSR-------LGDQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQ-------GCIAKMPVKWIA IESLCHGIFSQKSDVLS |||| .. |||| . IESLADRVYTSKSDVWA |
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Kinase | AqueK361.AA | InsR | 244-453 | 34 | 1.9e-39 | 130.13 | In-house | 1-206 (278) | Show / Hide |
Range on Protein: 244-453 Range on HMM: 1-206/278 Sequence Identity: 34% (74 aa) IQVLEVTGQGEFGIVYRA-LMTLKSDEMPQ--VVAIKTLKGLFSKSDIHSFVEECITMSNFDDPNILPLFGVSLDLGPAPCIIMPFMSRGSLLSYLEKER | . ||| || || . . .|| .||||.. | . | | | .|. .. |.|| |. ..| .| .| | ||| | IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPM-YVVMEMMTYGDLKSYLRSRR PNLT--VTDISDKDAVLNVRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGIIKIANFGLTEDIYMECYFNQFTDESESSKNVKLPVKWMAIE | ... .. | . |.. ... || |||. |||||||.||||... . .||. ||.| ||| | .. .||| ||| | PEEEFNNPGCNRNQHVP-CLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRK-------GGKGMLPVRWMAPE SLCHGIFSQKSDVLS || |.|. .||| | SLKDGVFTTHSDVWS |
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Kinase | AqueK361.AA | TyrKc | 244-463 | 25 | 1.2e-37 | 132.28 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 244-463 Range on HMM: 1-280/280 Sequence Identity: 25% (78 aa) IQVLEVTGQGEFGIVYRALMTLKSDEMPQVVAIKTLK-GLFSKSDIHSFVEECITMSNF--DDPNILPLFGVSLDLG------PAPCIIMPFMSRGSLLS |. ... | |.||.||.. .. . ||.|.|| . . | .| |... . |||. |.|| .. | . ..|.| .|. |.|.. ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD YLEKERPNLTVTDISDKDAVLNVRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGIIKIANFGLTEDIYME-CYFNQFTDESESSK------N || | ||. |.. |.|| .|.|.|.|| ||.|....|||||||||...||...||. |||. ||| . . ||.. . . YLRKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-----ESKDYYRKKEHKG VK--LPVKWMAIESLCHGIFSQKSDV----------------------------------------LSRSKV---------------------------- | ||..|||.|.. .|.|. |||| . . . GKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR ----QLGLEL .. .. PTFSEIHECF |
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Kinase | AqueK361.AA | ALK | 244-451 | 33 | 2.5e-34 | 115.91 | In-house | 1-200 (273) | Show / Hide |
Range on Protein: 244-451 Range on HMM: 1-200/273 Sequence Identity: 33% (73 aa) IQVLEVTGQGEFGIVYRALMTL-KSDEMPQVVAIKTLKGLFSKSDIHSFVEECITMSNFDDPNILPLFGVSLDLGPAPCIIMPFMSRGSLLSYLEKERPN |. . . |.| || || .. . | | ||.|||. . |. | | | |..|...|. . |.... | |. .|. | ..|.| ||. ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH LT---VTDISDKDAVLNVRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENG---IIKIANFGLTEDI-YMECYFNQFTDESESSKNVK--LPVK . . || || .|. ||.| || ..||.||| ||||| | . ||| || || | |. |. . .||| PESLQPSQLTMKD--------LLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYR---------KGGRAMMPVK WMAIESLCHGIFSQKSDV || | . ||| |.|| WMPPEAFMDGIFTSKTDV |
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Kinase | AqueK361.AA | Src | 244-451 | 32 | 5.2e-34 | 112.91 | In-house | 1-183 (255) | Show / Hide |
Range on Protein: 244-451 Range on HMM: 1-183/255 Sequence Identity: 32% (69 aa) IQVLEVTGQGEFGIVYRALMTLKSDEMPQVVAIKTLKGLFSKSDIHSFVEECITMSNFDDPNILPLFGVSLDLGPAPCIIMPFMSRGSLLSYLEKERPNL |. .. ||| || |. .. . . ||.|||| . . | .| .| ... .... |. | . | |. .||.|||| || | IKLCRKLGQGQFGEVWMGYWNGNTK-----VAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKK----- TVTDISDKDAVLNVRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGIIKIANFGLTEDIY--MECYFNQFTDESESSKNVKLPVKWMAIESLC ... |... ||. . |||.|| || |. ..|||||||| ..|| . |.| ||| | . | .... |.|.||.| | . -----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY--------CARHGAKFPIKWTAPEAIN HGIFSQKSDV .| |..|||| YGRFTIKSDV |
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Kinase | AqueK361.AA | Ror | 362-451 | 45 | 2.7e-23 | 83.7 | In-house | 122-204 (308) | Show / Hide |
Range on Protein: 362-451 Range on HMM: 122-204/308 Sequence Identity: 45% (41 aa) LCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGIIKIANFGLTEDIYMECYFNQFTDESESSKNVKLPVKWMAIESLCHGIFSQKSDV | | .|.| || ||.| ||||||||||||.. | .||. ||| ||| | . | .|. ||. |. | || ||. LHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQ---HKSW----MPIRWMSPEAIMYGKFSEDSDI |
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Kinase | AqueK361.AA | HMTK | 361-406 | 58 | 1.6e-20 | 68.35 | In-house | 130-175 (291) | Show / Hide |
Range on Protein: 361-406 Range on HMM: 130-175/291 Sequence Identity: 58% (27 aa) LLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGIIKIANFGLT .| .| |.|.|| |.|||..||.|||||||.. .| ..||| |||| QLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLT |
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Kinase | AqueK361.AA | Pkinase | 244-405 | 25 | 1.2e-15 | 56.44 | Pfam | 1-158 (293) | Show / Hide |
Range on Protein: 244-405 Range on HMM: 1-158/293 Sequence Identity: 25% (44 aa) IQVLEVTGQGEFGIVYRALMTLKSDEMPQVVAIKTLKGLFSKS--DIHSFV--EECITMSNFDDPNILPLFGVSLDLGPAPCIIMPFMSRG----SLLSY ...... |.| || ||.. .. .||.|..| || |.. . | .| | ... |||. |... | .. ....|... | .| .| YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQI-MKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDY LEKERPNLTVTDISDKDAVLN--VRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGII----KIANFGL .. .. ... ....|...|. |. |. ..|||| |..||.|| | ||. ||| IST------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL |
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Kinase | AqueK361.AA | S_TKc | 244-464 | 16 | 3.7e-11 | -13.31 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 244-464 Range on HMM: 1-231/231 Sequence Identity: 16% (44 aa) IQVLEVTGQGEFGIVYRALMTLKSDEMPQVVAIKTLKGLFSKSDIHSFVEECITMSNFDDPNILPLFGVSLDLGPAPCIIMPFMSR--GSLLSYLEKERP ..|.. |.| || ||.. . ..|||| .| .. | ... . ||| |..| | ...| ... |.|..|..| .. YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGR N-----LTVTDISDKDAVLNVRKQLLCICLQVAKGMFYLASQHFVHRDLAARNCMIDENGIIKIANFGLTEDI----------------YME-------- . .. .. ... |..... |. |....|||| | ..|| |||. ||| . | HGLRFPFPE-HAR-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSC -------CY----FNQFTDESESSKNVKLPVKWMAIESLCHGIFSQKSDVLSRSKVQLG-------LELA .. | .. . |... .. ... . | . GCILYEMLCGYPPFP---QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | AqueK361.AA | HMTK | 428-451 | 61 | 1.8e-09 | 29.27 | In-house | 192-217 (291) | Show / Hide |
Range on Protein: 428-451 Range on HMM: 192-217/291 Sequence Identity: 61% (16 aa) VKLPVKWMAIESLC--HGIFSQKSDV ||||.||||.| . .||| |||| VKLPIKWMAPEAMDGKRKIFSEKSDV |
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Kinase | AqueK361.AA | Ror | 244-312 | 34 | 8e-09 | 31.5 | In-house | 1-70 (308) | Show / Hide |
Range on Protein: 244-312 Range on HMM: 1-70/308 Sequence Identity: 34% (24 aa) IQVLEVTGQGEFGIVYR-ALMTLKSDEMPQVVAIKTLKGLFSKSDIHSFVEECITMSNFDDPNILPLFGV ....| | . || ||. || . . .. |||||.| | | | |. .. ||| | || VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGV |
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Kinase | AqueK361.AA | HMTK | 244-314 | 24 | 1e-06 | 19.19 | In-house | 1-94 (291) | Show / Hide |
Range on Protein: 244-314 Range on HMM: 1-94/291 Sequence Identity: 24% (23 aa) IQVLEVTGQGEFG-----------------IVYRALMT------LKSDEMPQVVAIKTLKGLFSKSDIHSFVEECITMSNFDDPNILPLFGVSL . .. | |.| || || |. . . |. .| |.|.| | |. | |...|.... ||.. | ||.. LKAIKVIGAGQFGMVQCLRLAPPDEGCTSLKVYLAEWSVKDGDGKDDSNQPHHRAVKMLRGDASHEDREEFLREAEVMCQLRHPNLVQLVGVCM |