Gene AqueK354 (A.queenslandica)

AqueK354

Species: A.queenslandica
Alias: AqueK354
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK354.AA Protein None 178 None Fasta, JSON
AqueK354.kin_dom Protein Kinase Domain None 152 None Fasta, JSON

Protein domain

Protein domains of AqueK354.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK354.AA Pkinase_Tyr 1-152 46 5.4e-72 244.44 Pfam 124-270 (270) Show / Hide 
Range on Protein: 1-152
Range on HMM: 124-270/270
Sequence Identity: 46% (72 aa)

MCYLASQKFIHRDLAARNCMIDDNGIIKVADFGLSEDIYSQNYF-RQLEDDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVP-YP
| ||.|...||||||||||....|...|..||||. |||.  |  |. ..       ||| ||||.|.|..| |..||||||.|||.||.|..|. | ||
MEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG------KLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYP

GLDPMGIVELL-NTGGRLHTPNNEACSNEIYSLMTSCWSESPDDRPVFSDLVSSI
|...  ..|..   |.|.  | |  |. |||.||..|| . |.||| ||.... .
GMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK354.AA TK 1-152 30 1.1e-67 225.78 In-house 247-486 (486) Show / Hide 
Range on Protein: 1-152
Range on HMM: 247-486/486
Sequence Identity: 30% (73 aa)

MCYLASQ------KFIHRDLAARNCMIDDNGI-----------IKVADFG--------LSEDIYS-QNYFRQLEDDNNS-----------------SPVK
| ||.|.      .|.|||||||||....|..           .|.||||        |. |||| ..| |. . . .                  |  |
MEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGK

LPLKWMALESIHDGL---------FSEKSDVWSYGVLCWEVFSLGRVPYPG-LDP---------MGIVELLNTGGR------------LHTPNNEACS--
||..||| |.. |.          |..||||||.|||.||.|..|..||.| ..            ..|.| .|||            .  |  . |.  
LPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDW

------------NEIYSLMTSCWSESPDDRPVFSDLVSSI
             |.| ||..||.. |.||| ||.|.. .
MRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK354.AA UTK 1-152 36 1.7e-60 205.63 In-house 131-296 (296) Show / Hide 
Range on Protein: 1-152
Range on HMM: 131-296/296
Sequence Identity: 36% (63 aa)

MCYLASQKFIHRDLAARNCMIDDNG-------IIKVADFG---LSEDIY---------SQNYFRQLEDDNNSSPVKLPLKWMALESIHDG-LFSEKSDVW
| ||.|..|.||||||||| .....       ..|.||||   .| ...         ...|... ..|      ..|..||| |.. ..  |..|||||
MQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQD------RWPIRWMAPEALTHHTRFTTKSDVW

SYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEACSNEIYSLMTSCWSESPDDRPVFSDLVSSI
|.||.|||... ||.||||.  | ... .  |||.. | ...|. ..| ||..||  .|..|| | |||. .
SFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK354.AA Met 1-146 43 1.1e-59 194.23 In-house 117-271 (271) Show / Hide 
Range on Protein: 1-146
Range on HMM: 117-271/271
Sequence Identity: 43% (70 aa)

MCYLASQKFIHRDLAARNCMIDDNGIIKVADFGLSEDI-YSQNYFRQLEDDNNSSPVKLPLKWMALESIH--------DGL-FSEKSDVWSYGVLCWEVF
| |.|||||.|||||.||||.|   ..|||||||. |. |   |  |    .   | .||.||||.|.          .   |. |||||| ||. || .
MMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQ---MHHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELM

SLGRVPYPGLDP-MGIVELLNTG--GRLHTPNNEACSNEIY-SLMTSCWSESPDDRPVFS
  | .|||  |.   |   | .|   ||  |  | |   .|  .| .||. .| ||| ||
TRGAPPYPHVDNWFDITHWLHQGETRRLPQP--EYCPDHLYTDVMLCCWHANPEDRPQFS
Kinase AqueK354.AA TK-Unique 1-152 39 3.6e-59 202.63 In-house 144-294 (294) Show / Hide 
Range on Protein: 1-152
Range on HMM: 144-294/294
Sequence Identity: 39% (63 aa)

MCYLAS--QKFIHRDLAARNCMIDDNGIIKVADFGLSEDIYSQNYFRQLEDDNNSSPVKLPLKWMALESIH--DGLF-SEKSDVWSYGVLCWEVFSLGRV
| ||||  .|..||||.|||... .....|..|||...|.|        . ... |  ..|..|||.||.   .| . ..||||||.||| ||.|.||  
MEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-----NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGAC

PYPGLDPMGIVELLNTGGRLHTPNNEAC-SNEIYSLMTSCWSESPDDRPVFSDLVSSI
||||...  |.|..  | |.  |..  | |.|.|.|| |||...|..|| |..... .
PYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK354.AA VEGFR 1-152 45 1.7e-58 200.69 In-house 186-332 (332) Show / Hide 
Range on Protein: 1-152
Range on HMM: 186-332/332
Sequence Identity: 45% (70 aa)

MCYLASQKFIHRDLAARNCMIDDNGIIKVADFGLSED-IYSQ-NYFRQLEDDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYP
| .|||.| |||||||||  .. | ..|  ||||. . ||.  .| |. .        .||.||||.||| |  .. .||||||||. ||.|||| .|||
MEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQ------GRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYP

GLD-PMGIVELLNTGGRLHTPNNEACSNEIYSLMTSCWSESPDDRPVFSDLVSSI
| .        |. | |. .|  . |  |||  | .||.. |  || ||.||   
GVQIDEEFCNRLKDGYRMRAP--DYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase AqueK354.AA FGFR 1-152 43 6.9e-56 188.96 In-house 149-293 (293) Show / Hide 
Range on Protein: 1-152
Range on HMM: 149-293/293
Sequence Identity: 43% (67 aa)

MCYLASQKFIHRDLAARNCMIDDNGIIKVADFGLSEDIYSQNYFRQLEDDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGL
| ||||.| |||||||||  . |. ..|..||||. || .  |.|   .        || ||||.|.  |  .  .||||||||| ||.. .|  |||. 
MEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNG------RLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHI

D-PMGIVELLNTGGRLHTPNNEACSNEIYSLMTSCWSESPDDRPVFSDLVSSI
     . ..| .| |.  | |  ||.||| .| .|| ..|..|| |  || ..
PSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase AqueK354.AA KIN6 1-152 42 6.7e-55 179.78 In-house 157-305 (305) Show / Hide 
Range on Protein: 1-152
Range on HMM: 157-305/305
Sequence Identity: 42% (67 aa)

MCYLASQKFIHRDLAARNCMIDDNG---IIKVADFGLSEDIYSQNYFRQLEDDNNSSPVK-LPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVP
| ||.|  .|||||||||  ..        |. ||||   .|        .   .|   . ||.||||.|..    || ||||||.||| .|.|||| ||
MEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMD------QFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVP

YPGLD-PMGIVELLNTGGRLHTPNNEACSNEIYSLMTSCWSESPDDRPVFSDLVSSI
||..  |  . | .  |.|.  | .  |..|||  | |||.| ||||| |...   .
YPEMQRPTEMIEHHRSGRRPKHPKW--CPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase AqueK354.AA Tec 1-154 43 4.1e-53 182.78 In-house 110-254 (254) Show / Hide 
Range on Protein: 1-154
Range on HMM: 110-254/254
Sequence Identity: 43% (68 aa)

MCYLASQKFIHRDLAARNCMIDDNGIIKVADFGLSEDIYSQNYFRQLEDDNNSSPV--KLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYP
| || ...||||||||||| ..|....||.|||..         |   ||   | |  | | || . |  |   .| |||||..||| |||||.|..||.
MAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMT---------RYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE

GLDPMGIVELLNTGGRLHTPNNEACSNEIYSLMTSCWSESPDDRPVFSDLVSSINA
 .. . .||   .| ||. |  . ||..||  | .||.|.|..|| |..| ..|  
NMSNSEVVEHVSQGHRLYRP--HLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK354.AA Axl 1-150 46 4.5e-53 182.64 In-house 126-267 (267) Show / Hide 
Range on Protein: 1-150
Range on HMM: 126-267/267
Sequence Identity: 46% (70 aa)

MCYLASQKFIHRDLAARNCMIDDNGIIKVADFGLSEDIYSQNYFRQLEDDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGL
| ||....||||||||||||. ..  . |||||||  |||  |.||          |.| ||.|.||. | ..  |||||..||  ||.   |. ||||.
MEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQ------GCIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGV

DPMGIVELLNTGGRLHTPNNEACSNEIYSLMTSCWSESPDDRPVFSDLVS
.   . . |  | ||  |  | | .|.| || .||.  | ||| || |  
ENHEMYDYLIHGHRLKQP--EDCMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase AqueK354.AA HMTK 1-151 38 2.7e-52 180.04 In-house 141-291 (291) Show / Hide 
Range on Protein: 1-151
Range on HMM: 141-291/291
Sequence Identity: 38% (60 aa)

MCYLASQKFIHRDLAARNCMIDDNGIIKVADFGLSEDIY-SQNYFRQLEDDNNSSPVKLPLKWMALESIH--DGLFSEKSDVWSYGVLCWEVFSLGRVPY
| |.||| ..|.|||||||.. .| ..|.|||||.  .   |.|...   ....  ||||.|||| |     .. ||||||||..||..||... |..||
MAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHL---RKHM--VKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPY

P--GLDPMGIVELLNTGGRLHTPNNEACSNEIYSLMTSCWSESPDDRPVFSDLVSS
.  ..    .   .  |.||  |.  .|. ... ||..||   |. || |..|  .
ESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM
Kinase AqueK354.AA TyrKc 1-152 24 2.4e-22 81.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-152
Range on HMM: 1-280/280
Sequence Identity: 24% (70 aa)

MC--------------------------------------------------------------------------------------------------
                                                                                                    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

--------------YLASQKFIHRDLAARNCMIDDNGIIKVADFGLSEDIYSQ-------NYFRQLEDDNNSSPVK--LPLKWMALESIHDGLFSEKSDV
              ||.|...||||||||||....|...|..||||| |||.         | |. |    ..  |  ||..|||.|.| .| |..||||
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKE----HKGGKTMLPIRWMAPECINYGKFTTKSDV

WSYGVLCWEVFSLGRVPYPG-----LDPMGIVELLNTGGRLHTPNNEA------CSNEIYSLMTSCWSESPDDRPVFSDLVSSI
||.||..||.|..|  ||||     ...  ..|.. .|.|.  | |        |. |.|..|..|| | |.||| ||.... .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK354.AA Pkinase 6-152 24 5.5e-16 57.6 Pfam 126-293 (293) Show / Hide 
Range on Protein: 6-152
Range on HMM: 126-293/293
Sequence Identity: 24% (44 aa)

SQKFIHRDLAARNCMIDDNGII----KVADFGLSEDIYSQNYFRQLEDDNNSSPVKLPLKWMALESIH-DGLFSEKSDVWSYGVLCWEVFSLGRVPYPGL
|...|||||   |..||.|| |    |..||||.. ..       .  .   . .   . .|| | |  .   . |.|.||.|....|... || |.|| 
SMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGH

------DPMGIVELLNTGGRLHTPNNEACS-------------------NEIYSLMTSCWSESPDDRPVFSDLVSS--I
      |.| ... .. |..|| .  . ||                    |  .....|.   | .|| . ... .  .
CWHDNHDQMQMIC-RIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK354.AA S_TKc 2-156 12 7e-06 -90.2 SMART 15-231 (231) Show / Hide 
Range on Protein: 2-156
Range on HMM: 15-231/231
Sequence Identity: 12% (33 aa)

CYLASQKF--------------------------------------------------------------------------------------------
.|..  |                                                                                             
VYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHG

-IHRDLAARNCMIDDNGIIKVADFGLSEDIYSQNYFRQLEDDNNSSPVKLPLKWMALESIHDGLFSE-KSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVE
 |||||   | ..|.   ||..||||.  .               . .   . .|| | .    ..  |.|.|| |.. .| .. |. |.|  ... . .
IIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFK

LLNTGGRLHTPNNEACSNEIYSLMTSCWSESPDDRPVFSDLVSSI-----NALI
..              | |  ...  |.   |..||   ..  .         .
KIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF