Gene AqueK352 (A.queenslandica)

AqueK352

Species: A.queenslandica
Alias: AqueK352
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK352.AA Protein None 565 None Fasta, JSON
AqueK352.kin_dom Protein Kinase Domain None 144 None Fasta, JSON

Protein domain

Protein domains of AqueK352.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK352.AA Pkinase_Tyr 309-452 41 2e-60 205.26 Pfam 1-142 (270) Show / Hide 
Range on Protein: 309-452
Range on HMM: 1-142/270
Sequence Identity: 41% (62 aa)

IKITCELGEGAFGIVYKGKVSQGSLSEIEDVAIKTLKEHSSVEQ--IKEFISESETMLRL-DHPNVLKLLGVCFDTEDQ-LPAIVLPFMANGDLKSFLVE
|..  .||||||| ||||.      ..  .||.|.|||... ||  ...|..| ..|  | .|||...|.||| | ...  . ||...|..|||...| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

KRGHNEPNILPENLSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC
.|        ...|.|.|||.||..||.||.||......|||||||||
HR------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNC
Kinase AqueK352.AA TK 309-452 22 9.3e-53 174.79 In-house 1-271 (486) Show / Hide 
Range on Protein: 309-452
Range on HMM: 1-271/486
Sequence Identity: 22% (60 aa)

IKITCELGEGAFG---IVYKGKVSQGSLSEI---------------------EDVAIKTLKE--HSSVEQIKE--------------FISESETML--RL
|..  .||||.||    ||||.. ... ..                      ..||.|.|||  ..| |. ..              . .| . |.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHPNVLKLLGVCFDTED----------QLPAIVLPFMANGD----LKSFLVEKRGHNEPNIL--------------------------------------
.|||...|.|||.. |           . . ||. .|..||    |...| ..|..  ..                                        
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------PENLSMEDLLSMCLDIARGMNYLSEQ------KFVHRDLAARNC
                            ...|.|..|| ||..||.|| ||...      .|||||||||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNC
Kinase AqueK352.AA Met 310-452 37 4e-52 169.05 In-house 1-135 (271) Show / Hide 
Range on Protein: 310-452
Range on HMM: 1-135/271
Sequence Identity: 37% (55 aa)

KITCELGEGAFGIVYKGKVSQGSLSEIEDVAIKTLK--EHSSVEQIKEFISESETMLRLDHPNVLKLLGVCFDTEDQLPAIVLPFMANGDLKSFLVEKRG
     .| | || ||.|. .. . .. . .|.|.|.      ...| .|  |  .|  .||||||.|.|.| | |  .| .|||.|..||||.|      
HFDDVIGQGHFGCVYHGMYHD-NDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQ-

HNEPNILPENLSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC
         |. . ||.. |...|.||.|. .|||||||||.|||
--------NNPCVRDLIEFCHQVAKGMMYMASQKFVHRDLACRNC
Kinase AqueK352.AA UTK 309-452 41 6.7e-48 161.94 In-house 1-149 (296) Show / Hide 
Range on Protein: 309-452
Range on HMM: 1-149/296
Sequence Identity: 41% (64 aa)

IKITCELGEGAFGIVYKGKVSQGS-LSEIEDVAIKTLKEHSSVEQIKE----FISESE---TMLRLD-HPNVLKLLGVCFDTEDQLPAIVLPFMANGDLK
...  .||.||||.|.|... | | ...  |||.|....|.. .| .|    |. |.     | ... |||||.|.|||.. |   ..||. .|.|||| 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP--WMIVTEYMENGDLR

SFLVEKRGHNEPNILPENLSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC
|.|   | . .|.. |. |.....|.|..||||||.||....|||||||||||
SYLR--RHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNC
Kinase AqueK352.AA TK-Unique 309-452 29 1.5e-45 155.09 In-house 1-164 (294) Show / Hide 
Range on Protein: 309-452
Range on HMM: 1-164/294
Sequence Identity: 29% (49 aa)

IKITCELGEGAFGIVYKGKVSQGS--LSEIEDVAIKTLKEHSSVEQIKEFISESETMLRLD-HPNVLKLLGVCFDTEDQLPAIVLPFMANGDLKSFLVEK
...  ..|||||| |..|.|....   ..   ||.|.||.... .. ..| .| . |  |. |||....||.| ... . . |.......|.| ..| ..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTC

RG----------------HNEPNILPENLSMEDLLSMCLDIARGMNYLSE--QKFVHRDLAARNC
|.                |...  ..| .|..||.. . .||.||.||..  .|.|||||.|||.
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNV
Kinase AqueK352.AA ALK 309-452 43 3.5e-40 136.39 In-house 1-142 (273) Show / Hide 
Range on Protein: 309-452
Range on HMM: 1-142/273
Sequence Identity: 43% (64 aa)

IKITCELGEGAFGIVYKGKVSQ--GSLSEIEDVAIKTLKEHSSVEQIKEFISESETMLRLDHPNVLKLLGVCFDTEDQLPAIVLPFMANGDLKSFLVEKR
|.    || |||| || |..|   |  ...  ||.|||.|  | ..   |  |   | . .|.|| ...|.||.    .  ||| .|. ||.|||| | |
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQ-VAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYM--IVLEYMEGGDMKSFLRECR

GHNEPNILPENLSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC
 | |  . |  | | |||  |.|.| |  || |..|.||| |||||
PHPE-SLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNC
Kinase AqueK352.AA InsR 309-452 36 6.1e-40 131.79 In-house 1-150 (278) Show / Hide 
Range on Protein: 309-452
Range on HMM: 1-150/278
Sequence Identity: 36% (55 aa)

IKITCELGEGAFGIVYKG---KVSQGSLSEIEDVAIKTLKEHSSVEQIKEFISESETMLRLDHPNVLKLLGVCFDTEDQLPAIVLPFMANGDLKSFLVEK
| .  |.|.|.|| || |    . ..  .    .||||..|  |..   || .| . | . .. .| .|||||  .  |   .|  .|. |||||.|  .
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVC--SRGQPMYVVMEMMTYGDLKSYLRSR

RGHNEPNILPEN-----LSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC
|  .| | .. |      . .....|  .|. || ||   ||||||||.|||
RPEEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNC
Kinase AqueK352.AA Axl 309-453 41 1.7e-37 130.3 In-house 1-145 (267) Show / Hide 
Range on Protein: 309-453
Range on HMM: 1-145/267
Sequence Identity: 41% (62 aa)

IKITCELGEGAFGIVYKGKVSQGSLSEIEDVAIKTLK-EHSSVEQIKEFISESETMLRLDHPNVLKLLGVCFDTED----QLPAIVLPFMANGDLKSFLV
. .   |||| || |  |.. |   | .  ||.|..| . ..  .| ||.||   |   |||||..|.|||. . .      | ..||||  ||| .||.
FVLGKMLGEGEFGSVMEGQLKQEDGS-FVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLL

EKRGHNEPNILPENLSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNCI
  |  ..|  ||    .  |.   .||| || |||...|.|||||||||.
YSRLGDQPFYLP----LQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCM
Kinase AqueK352.AA Fer 309-452 36 2.4e-37 124.77 In-house 1-142 (283) Show / Hide 
Range on Protein: 309-452
Range on HMM: 1-142/283
Sequence Identity: 36% (55 aa)

IKITCELGEGAFGIVYKGK-----VSQGSLS-EIEDVAIKTL-KEHSSVEQIKEFISESETMLR-LDHPNVLKLLGVCFDTEDQLPAIVLPFMANGDLKS
....  |||||||.||||.       ....  .  .|. |..  |... ||||||  |   |.  .||||| |. ||| | .  .  ||. |. .|.|.|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIM--IVMEFCNGGSLDS

FLVEKRGHNEPNILPENLSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC
.| .. .         ..|. ... ||...|.||.|| ... .|||.|||||
YLKKNKNK--------TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNC
Kinase AqueK352.AA Sev 309-452 40 9.3e-35 113.11 In-house 1-145 (277) Show / Hide 
Range on Protein: 309-452
Range on HMM: 1-145/277
Sequence Identity: 40% (60 aa)

IKITCELGEGAFGIVYKGKVSQGS--LSEIEDVAIKTLKEHSSVEQIKEFISESETMLRLDHPNVLKLLGVCFDTEDQLPAIVLPFMANGDLKSFLVEKR
 |    || |||| || | .       .|   ||||||.  |  .   ||  |   | .  |||.....|||.|.| |   |..  |  ||| ..|   |
LKLRRFLGSGAFGEVYEGQAKDIDGVGEEEQRVAIKTLRKGSTDQEKQEFLKEAHLMSKFKHPNIVCQMGVCLDNEPQ--YIIMEHMEGGDLLCYLRAAR

GHNEPNILPEN-LSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC
.    | .|   |.  ||. ||.||..|  || .  |||||||.|||
MTTFQNPQPTAGLTLMDLVEMCIDISKGCEYLEDMHFVHRDLACRNC
Kinase AqueK352.AA Ror 309-452 40 1.1e-34 121.61 In-house 1-150 (308) Show / Hide 
Range on Protein: 309-452
Range on HMM: 1-150/308
Sequence Identity: 40% (61 aa)

IKITCELGEGAFGIVYKGKVSQGS-LSEIEDVAIKTLKEHSSVEQIKEFISESETMLRLDHPNVLKLLGVCFDTEDQLPAIVLPFMANGDLKSFLVEKRG
..   ||||..|| ||||.  ..    .   |||||.|.  |. | ..|  | . | .|.|||. .|||||  | ||    .  .|..|||  ||. .  
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVC--TMDQPYCMLFEYMNHGDLHEFLIMRSP

HNEPN-------ILPENLSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC
|                |.  | |   . || || |||   |||||||||||
HSDHGCSSDDDRMVKSSLDHPDFLHIAIQIAAGMEYLSSHHFVHRDLAARNC
Kinase AqueK352.AA TyrKc 309-546 21 1.4e-25 92.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 309-546
Range on HMM: 1-280/280
Sequence Identity: 21% (70 aa)

IKITCELGEGAFGIVYKGKVSQGSLSEIEDVAIKTLKEHSSVEQIKEFISESETMLRL--DHPNVLKLLGVCFDT-----EDQLPAIVLPFMANGDLKSF
|.   .|||||||.||||. .       ..||.|.|||..    ...|..| . | .|  .|||...|.||| .      ... . ||. .|..||||..
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LVEKRGHNEPNILPENLSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC-IDERL-----------PILVL--------IVSG----LLT--------
| ..|..         |.|.||||.|..||.||.||......||||||||| ..|..            |             .                
LRKHRPK---------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

--------------------------VSDCQEDILQDI---VTNVSMRASLFSGKMTDCSEF---ISLSNYNRYGNYTHSFFSYLTSRVVHVNQKFHMTM
                           ...|.    .|   ..|  ... . .|.. .. .    .|                   .  |.  .. .. |
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------F--VCCPDEMYQIM

LLMYQL------------WCL
.   .              |.
KQCWHEDPEDRPTFSEIHECF
Kinase AqueK352.AA Pkinase 309-447 23 2.4e-18 65.95 Pfam 1-134 (293) Show / Hide 
Range on Protein: 309-447
Range on HMM: 1-134/293
Sequence Identity: 23% (35 aa)

IKITCELGEGAFGIVYKGKVSQGSLSEIEDVAIKTLKEHSSVE-QIKEFIS--ESETMLRLDHPNVLKLLGVCFDTEDQLPAIVLPFMANG----DLKSF
..|   .|.|.|| |||..    .      ||.|..| ..  . . .. .   | . |.||.|||...|.... |  .. . .|.... .|    ||...
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDY

LV-EKRGHNEPNILPENL--SMEDLLSMCLDIARGMNYLSEQKFVHRDL
.  ...|         ..  |.... .... |.||..|. .....||||
ISTWRHG---------CFYFSEWECKFYMYQILRGLEYCHSMGIIHRDL
Kinase AqueK352.AA S_TKc 309-556 15 7.8e-11 -18.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 309-556
Range on HMM: 1-231/231
Sequence Identity: 15% (46 aa)

IKITCELGEGAFGIVYKGKVSQGSLSEIEDVAIKTLKEHSSVEQIKEFISESETMLRLDHPNVLKLLGVCFDTEDQLPAIVLPFMAN--GDLKSFLVEKR
 .|  ..|.|||| |||..         . |||| .|        . ...| . . . .|||. ||..|. |   .   .|. .. .  |||........
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRG

GHNEPNILPENLSMEDLLSMCLDIARGMNYLSEQKFVHRDLAARNC-IDERLPILVLI---VSGLLTVSDCQEDILQDIVTNVSMRASLFSGKMTDCS--
.|     |.  ..  .  ...  |.....|. .....||||   |  .||    . ..   .. .|                           .| |   
RHG----LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL---------------------------TTFCGTP

-----EFISLSNYNRYGN---------------YT-HSFFSYLTSRVVHVNQKFHMTMLLMYQLWCL-------LTGMLN-------HHYL
     | .       ||                ..    |.    .. ..    .    .. ....            |.       | ..
WYMAPEVL------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF