Gene AqueK346 (A.queenslandica)

AqueK346

Species: A.queenslandica
Alias: AqueK346
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK346.AA Protein None 159 None Fasta, JSON
AqueK346.kin_dom Protein Kinase Domain None 102 None Fasta, JSON

Protein domain

Protein domains of AqueK346.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK346.AA Pkinase_Tyr 50-147 28 4.7e-31 105.79 Pfam 1-108 (270) Show / Hide 
Range on Protein: 50-147
Range on HMM: 1-108/270
Sequence Identity: 28% (31 aa)

LKLMETIGKGEYGLVYKGQLM--MKSKSRIVAVKTLKGQFEQSD--VDSLLEESIKMFRF-NHPNVLGLLGVCL-DAGP-SPYIILPYMENGSLLNWLKR
.......|.|..| |||| .   ....   ||||.|| .  ...   .....|   |  . .|||.. |.|||. . .| ..||...||..|.||. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

E---RNRI
    ....
HREDKQPL
Kinase AqueK346.AA Met 51-147 32 1.9e-29 93.49 In-house 1-101 (271) Show / Hide 
Range on Protein: 51-147
Range on HMM: 1-101/271
Sequence Identity: 32% (33 aa)

KLMETIGKGEYGLVYKGQLMM-KSKSRIVAVKTLK--GQFEQSDVDSLLEESIKMFRFNHPNVLGLLGVCLDAGP-SPYIILPYMENGSLLNWLKRERNR
 . . ||.| .| ||.|..   ...   .|.|.|.   . .   .   |.| | |  |.||||| |.|.|||    .|...||||..| |... . . | 
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

I
.
P
Kinase AqueK346.AA TK 50-145 21 6e-28 90.15 In-house 1-155 (486) Show / Hide 
Range on Protein: 50-145
Range on HMM: 1-155/486
Sequence Identity: 21% (33 aa)

LKLMETIGKGEYG---LVYKGQLMMKS-----------------------KSRIVAVKTLKGQFEQSDVDSLL---------------EESIKMFR---F
..| ...|.|..|    ||||.. ...                       .   ||||.||   ..|. . ..                | .||..   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHPNVLGLLGVCLDAGPS-----------PYIILPYMENGS----LLNWLKRERN
.|||.. |.|||.. .|.           ..|.. ||..|.    |...|.. |.
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRP
Kinase AqueK346.AA UTK 50-140 33 3.2e-22 72.83 In-house 1-101 (296) Show / Hide 
Range on Protein: 50-140
Range on HMM: 1-101/296
Sequence Identity: 33% (34 aa)

LKLMETIGKGEYGLVYKGQLMMKS---KSRIVAVKTLK-GQFEQSDVD---SLLEESI---KMFRFN-HPNVLGLLGVCLDAGPSPYIILPYMENGSLLN
..|....|.|..| |.|. .   |   .  .||||... . . | . .    ..||.     | .|. |||||.|.|||.. .| ..|.. |||||.|..
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

WL
 |
YL
Kinase AqueK346.AA TKL 56-140 24 8.1e-22 75.35 In-house 1-129 (364) Show / Hide 
Range on Protein: 56-140
Range on HMM: 1-129/364
Sequence Identity: 24% (32 aa)

IGKGEYGLVYKGQLMMKS------KSRIVAVKTLKGQF-------------------------EQSDVDSLLEESI-KMFRFNHPNVLGLLGVCLDAGP-
||.| .| ||||...  .      ... ||||..| .                          |.|     .|| |  | |..|||.. ..|.|.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------SPYIILPYMENGSLLNWL
            ..|.  |...||||. |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYL
Kinase AqueK346.AA TK-Unique 50-144 31 9.9e-19 61.31 In-house 1-100 (294) Show / Hide 
Range on Protein: 50-144
Range on HMM: 1-100/294
Sequence Identity: 31% (31 aa)

LKLMETIGKGEYGLVYKGQLMMKS----KSRIVAVKTLKGQFEQSDVDSLLEESIKMFRFN-HPNVLGLLGVCLDAGPSPYIILPYMENGSLLNWLKRER
|.. ..||.|..| |..|..  ..    | ..||||.||  . . |.. .| |   |     |||.. .||.| . . ...||..|...|.|.. |.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR
Kinase AqueK346.AA Csk 50-150 37 1.9e-18 59.59 In-house 1-95 (251) Show / Hide 
Range on Protein: 50-150
Range on HMM: 1-95/251
Sequence Identity: 37% (38 aa)

LKLMETIGKGEYGLVYKGQLMMKSKSRIVAVKTLKGQFEQSDVDSLLEESIKMFRFNHPNVLGLLGVCLDAGPSPYIILPYMENGSLLNWLKRERNRIVI
|.| |.||.||.| |  |..    . | |||| .|.      ....| |   |    |||   |.|| |. . . ||.. || .|.|...| | | | ||
LHLGECIGHGEFGDVMQGEY----QNRKVAVKCIKCDGNGM-AQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYL-RSRGRHVI

E
.
T
Kinase AqueK346.AA Sev 50-140 38 2.3e-18 57.65 In-house 1-94 (277) Show / Hide 
Range on Protein: 50-140
Range on HMM: 1-94/277
Sequence Identity: 38% (37 aa)

LKLMETIGKGEYGLVYKGQLMMKS----KSRIVAVKTLKGQFEQSDVDSLLEESIKMFRFNHPNVLGLLGVCLDAGPSPYIILPYMENGSLLNWL
|||    | | .| || ||..           ||.|||.     ..   .| |   | .|.|||.. ..|||||  |  |||.  || | ||  |
LKLRRFLGSGAFGEVYEGQAKDIDGVGEEEQRVAIKTLRKGSTDQEKQEFLKEAHLMSKFKHPNIVCQMGVCLDNEPQ-YIIMEHMEGGDLLCYL
Kinase AqueK346.AA Axl 50-140 37 2.7e-18 61.24 In-house 1-98 (267) Show / Hide 
Range on Protein: 50-140
Range on HMM: 1-98/267
Sequence Identity: 37% (37 aa)

LKLMETIGKGEYGLVYKGQLMMKS-KSRIVAVKTLK-GQFEQSDVDSLLEESIKMFRFNHPNVLGLLGVCLDAG-----PSPYIILPYMENGSLLNWL
. |  ..|.||.| |  |||      .  ||||..|   . ||...  | | . |  |.||||. |.|||. .      | | .|||.|  | |  .|
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFL
Kinase AqueK346.AA Eph 50-143 36 1.6e-17 55.29 In-house 1-98 (264) Show / Hide 
Range on Protein: 50-143
Range on HMM: 1-98/264
Sequence Identity: 36% (36 aa)

LKLMETIGKGEYGLVYKGQLMMK-SKSRI----VAVKTLKGQFEQSDVDSLLEESIKMFRFNHPNVLGLLGVCLDAGPSPYIILPYMENGSLLNWLKRE
.|. . || ||.| |..| | ..  |  .    ||.||||     ..    | |   |  |.|||.. | ||   . |   |.  |||||||  .|...
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPV-MIVTEYMENGSLDSFLRQH
Kinase AqueK346.AA MLK 50-149 28 1.2e-16 54.42 In-house 1-121 (291) Show / Hide 
Range on Protein: 50-149
Range on HMM: 1-121/291
Sequence Identity: 28% (35 aa)

LKLMETIGKGEYGLVYKGQLMMKS-KSRIVAVKTLKGQFEQSDVDS-----LLEESIKMFR-FNHPN----VLGLLGVCLDAGPSPYIILPYMENGSLLN
... | ||.| .| |.||.   |    .|||||  .  .. . .|.      .|. .. .| ..|||    .  ..||||. ..  .|.. |.|.||| |
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLKRER-----------NRIVI
 |. .|           | .|.
VLHGARSKWMDANHNQKNDRVY
Kinase AqueK346.AA Pkinase 50-147 29 6.8e-15 53.75 Pfam 1-103 (293) Show / Hide 
Range on Protein: 50-147
Range on HMM: 1-103/293
Sequence Identity: 29% (32 aa)

LKLMETIGKGEYGLVYKGQLMMKSKSRIVAVKTLKGQFEQSDVD--SLL--EESIKMFRFNHPNVLGLLGVCLDAGPSPYIILPYMENG----SLLNWLK
... ..||.| .| |||..   |. ..|||||..| . | |..|   ..  | .| | |.||||.. |.... | ....|....|.|.|    .|  ...
YHIGRKIGSGSFGCVYKCHH--KGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQI-MKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

-RERNRI
 ......
TWRHGCF
Kinase AqueK346.AA TyrKc 50-159 11 9e-06 -129.64 SMART 1-280 (280) Show / Hide 
Range on Protein: 50-159
Range on HMM: 1-280/280
Sequence Identity: 11% (34 aa)

LKLMETIGKGEYGLVYKGQLMMKSKSRIVAVKTLK-GQFEQSDVDSLLEESIKMFRF--NHPNVLGLLGVCLDAG------PSPYIILPYMENGSLLNWL
..| ...| |..| ||||..      . ||||.|| .      .  ...|   | ..  .|||.. |.|||.. |      . ..|.. ||..|.|.. |
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KRER-----------------------------------------NR----------IVIEET----------------SAE------------------
.. |                                         |.            |..                 ..                   
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

---------------------------------------------------D-----------------------------------EVM
                                                   .                                   | .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF