Gene AqueK343 (A.queenslandica)

AqueK343

Species: A.queenslandica
Alias: AqueK343
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK343.AA Protein None 2674 None Fasta, JSON
AqueK343.kin_dom Protein Kinase Domain None 96 None Fasta, JSON

Protein domain

Protein domains of AqueK343.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_SD22 AqueK343.AA LRR_SD22 122-143 63 2.6e-07 31.52 SMART 1-22 (22) Show / Hide 
Range on Protein: 122-143
Range on HMM: 1-22/22
Sequence Identity: 63% (14 aa)

LSKLETLWLNNNKINKIENIDT
|..||.|||..||| ||||.|.
LTNLEELWLSQNKIKKIENLDH
LRR_1 AqueK343.AA LRR_1 170-190 33 0.00062 18.12 Pfam 1-26 (26) Show / Hide 
Range on Protein: 170-190
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RLRKLNLSG-N--PLT-SLEE--LSQL
.|..|.||| |  .|| .. .  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP AqueK343.AA LRR_TYP 144-167 29 0.015376 14.71 SMART 1-24 (24) Show / Hide 
Range on Protein: 144-167
Range on HMM: 1-24/24
Sequence Identity: 29% (7 aa)

LTELLDLNLASNYISTLDNGSLSS
|..|  |.| .| ...| .| ...
LPNLRELDLSNNQLTHLPPGAFQG
LRR_SD22 AqueK343.AA LRR_SD22 168-189 31 0.037525 13.84 SMART 1-22 (22) Show / Hide 
Range on Protein: 168-189
Range on HMM: 1-22/22
Sequence Identity: 31% (7 aa)

FHRLRKLNLSGNPLTSLEELSQ
...|. | ||.| ....| |..
LTNLEELWLSQNKIKKIENLDH
LRR_TYP AqueK343.AA LRR_TYP 168-190 41 0.057285 10.03 SMART 1-24 (24) Show / Hide 
Range on Protein: 168-190
Range on HMM: 1-24/24
Sequence Identity: 41% (10 aa)

FHRLRKLNLSGNPLTSL-EELSQL
 . ||.|.||.| ||.| ... | 
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 AqueK343.AA LRR_1 124-144 22 0.059163 11.1 Pfam 1-26 (26) Show / Hide 
Range on Protein: 124-144
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

KLETLWLNN-N--KIN-KIEN--IDTL
.|..| |.. |  ..  .| .  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP AqueK343.AA LRR_TYP 122-143 25 0.207491 5.45 SMART 1-24 (24) Show / Hide 
Range on Protein: 122-143
Range on HMM: 1-24/24
Sequence Identity: 25% (6 aa)

LSKLETLWLNNNKINKI-ENI-DT
|..|..| |.||..  . ... . 
LPNLRELDLSNNQLTHLPPGAFQG
LRR_SD22 AqueK343.AA LRR_SD22 97-121 40 0.216442 7.64 SMART 1-22 (22) Show / Hide 
Range on Protein: 97-121
Range on HMM: 1-22/22
Sequence Identity: 40% (10 aa)

LTNCPQLVKVYFYSNKIKAITGISH
|||   |.  ....|||| | ...|
LTN---LEELWLSQNKIKKIENLDH
LRR_1 AqueK343.AA LRR_1 146-168 14 4.270956 4.51 Pfam 1-26 (26) Show / Hide 
Range on Protein: 146-168
Range on HMM: 1-26/26
Sequence Identity: 14% (4 aa)

ELLDLNLAS-N--YIS-TLDNGSLSSF
 |  |.| . |   .. .. .... ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 AqueK343.AA LRR_1 80-100 14 32.354535 1.39 Pfam 1-26 (26) Show / Hide 
Range on Protein: 80-100
Range on HMM: 1-26/26
Sequence Identity: 14% (4 aa)

SLKELWICE-G--DIE-VIED--LTNC
.|..| .       ..  | .  . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 AqueK343.AA LRR_1 102-122 14 46.216424 0.84 Pfam 1-26 (26) Show / Hide 
Range on Protein: 102-122
Range on HMM: 1-26/26
Sequence Identity: 14% (4 aa)

QLVKVYFYS-N--KI-KAITG--ISHL
.| . .. . |  .. . |    . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP AqueK343.AA LRR_TYP 673-695 45 0.026524 12.77 SMART 1-24 (24) Show / Hide 
Range on Protein: 673-695
Range on HMM: 1-24/24
Sequence Identity: 45% (11 aa)

MPNLHVLDLSFNRLATL-DGLKKN
.||| .||||.|.| .| .|.  .
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 AqueK343.AA LRR_1 675-695 29 0.063132 11.0 Pfam 1-26 (26) Show / Hide 
Range on Protein: 675-695
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

NLHVLDLSF-N--RLA-TLDG--LKKN
|| .||||  |  .|  ..    . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_SD22 AqueK343.AA LRR_SD22 673-694 31 0.109222 10.06 SMART 1-22 (22) Show / Hide 
Range on Protein: 673-694
Range on HMM: 1-22/22
Sequence Identity: 31% (7 aa)

MPNLHVLDLSFNRLATLDGLKK
. || .|.||.|..  ...| .
LTNLEELWLSQNKIKKIENLDH
LRR_TYP AqueK343.AA LRR_TYP 629-652 33 0.347966 3.61 SMART 1-24 (24) Show / Hide 
Range on Protein: 629-652
Range on HMM: 1-24/24
Sequence Identity: 33% (8 aa)

LEFVKTLDLSCNRLTRFRFSSLLP
|   ..|||| |.||.     . .
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 AqueK343.AA LRR_1 631-650 34 1.165544 6.51 Pfam 1-26 (26) Show / Hide 
Range on Protein: 631-650
Range on HMM: 1-26/26
Sequence Identity: 34% (9 aa)

FVKTLDLSC-N--RLT-RFRFS--SL
  ..||||. |  .||  .  |  .|
NLQHLDLSGCNCCNLTGHIPPSCFNL
LRR_1 AqueK343.AA LRR_1 653-673 18 1.665844 5.96 Pfam 1-26 (26) Show / Hide 
Range on Protein: 653-673
Range on HMM: 1-26/26
Sequence Identity: 18% (5 aa)

HLSCLSISC-N--EIS-TAED--FAHM
.|  |..|. |   .. .  .  | ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 AqueK343.AA LRR_1 778-798 18 38.545101 1.12 Pfam 1-26 (26) Show / Hide 
Range on Protein: 778-798
Range on HMM: 1-26/26
Sequence Identity: 18% (5 aa)

QITALDLTD-M--HVH-QISC--LDQL
... ||| .    ..  .|..  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP AqueK343.AA LRR_TYP 835-857 33 0.078256 8.92 SMART 1-24 (24) Show / Hide 
Range on Protein: 835-857
Range on HMM: 1-24/24
Sequence Identity: 33% (8 aa)

LTSLQEFYASHNYLENLR-QLFSL
|..|.| . |.| |. |  ..|. 
LPNLRELDLSNNQLTHLPPGAFQG
LRR_SD22 AqueK343.AA LRR_SD22 835-853 40 0.390706 5.55 SMART 1-22 (22) Show / Hide 
Range on Protein: 835-853
Range on HMM: 1-22/22
Sequence Identity: 40% (9 aa)

LTSLQEFYASHNYL---ENLRQ
|| |.|.. |.| .   ||| .
LTNLEELWLSQNKIKKIENLDH
LRR_1 AqueK343.AA LRR_1 837-857 22 0.485071 7.86 Pfam 1-26 (26) Show / Hide 
Range on Protein: 837-857
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

SLQEFYASH-N--YLE-NLRQ--LFSL
.||. . |. |   |. ..    . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 AqueK343.AA LRR_1 815-835 18 0.820806 7.05 Pfam 1-26 (26) Show / Hide 
Range on Protein: 815-835
Range on HMM: 1-26/26
Sequence Identity: 18% (5 aa)

QLTYVNISR-N--YI-RDITG--IETL
.|.. ..|. |   . ..|    .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_SD22 AqueK343.AA LRR_SD22 953-974 36 0.042856 13.37 SMART 1-22 (22) Show / Hide 
Range on Protein: 953-974
Range on HMM: 1-22/22
Sequence Identity: 36% (8 aa)

LDNLVSLNLEHNSLTSFSGLIH
|.||..| | .| ......| |
LTNLEELWLSQNKIKKIENLDH
LRR_1 AqueK343.AA LRR_1 955-975 29 0.052636 11.28 Pfam 1-26 (26) Show / Hide 
Range on Protein: 955-975
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

NLVSLNLEH-N--SLT-SFSG--LIHL
|| .|.| . |  .|| ...   . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP AqueK343.AA LRR_TYP 975-998 29 0.179284 5.97 SMART 1-24 (24) Show / Hide 
Range on Protein: 975-998
Range on HMM: 1-24/24
Sequence Identity: 29% (7 aa)

LSKLKVLCLNHNRVEYLIRPTGSG
|..|..| |..|. . | . . .|
LPNLRELDLSNNQLTHLPPGAFQG
LRR_TYP AqueK343.AA LRR_TYP 953-974 33 0.339278 3.7 SMART 1-24 (24) Show / Hide 
Range on Protein: 953-974
Range on HMM: 1-24/24
Sequence Identity: 33% (8 aa)

LDNLVSLNLEHNSLTSFSGLI--H
| || .|.|..| ||.    .  .
LPNLRELDLSNNQLTHLPPGAFQG
LRR_SD22 AqueK343.AA LRR_SD22 975-993 31 0.424072 5.26 SMART 1-22 (22) Show / Hide 
Range on Protein: 975-993
Range on HMM: 1-22/22
Sequence Identity: 31% (7 aa)

LSKLKVLCLNHNRV---EYLIR
|..|..|.|..|.    | |  
LTNLEELWLSQNKIKKIENLDH
LRR_1 AqueK343.AA LRR_1 977-991 21 14.472676 2.63 Pfam 1-19 (26) Show / Hide 
Range on Protein: 977-991
Range on HMM: 1-19/26
Sequence Identity: 21% (4 aa)

KLKVLCLNH-N--RVE-YL
.|..| |.. |  ... ..
NLQHLDLSGCNCCNLTGHI
LRR_TYP AqueK343.AA LRR_TYP 1060-1083 29 0.001835 18.75 SMART 1-24 (24) Show / Hide 
Range on Protein: 1060-1083
Range on HMM: 1-24/24
Sequence Identity: 29% (7 aa)

LHHLTELVLDRNKIKCMQENSLQH
|..|.|| |..|...   .. .|.
LPNLRELDLSNNQLTHLPPGAFQG
LRR_SD22 AqueK343.AA LRR_SD22 1038-1059 45 0.002244 18.46 SMART 1-22 (22) Show / Hide 
Range on Protein: 1038-1059
Range on HMM: 1-22/22
Sequence Identity: 45% (10 aa)

LPGLRALFLQGNEISRIEGLDG
|  |. |.|..| |. ||.||.
LTNLEELWLSQNKIKKIENLDH
LRR_SD22 AqueK343.AA LRR_SD22 1106-1127 36 0.025382 14.96 SMART 1-22 (22) Show / Hide 
Range on Protein: 1106-1127
Range on HMM: 1-22/22
Sequence Identity: 36% (8 aa)

VKNLERLYLGMNRIQDYSELEK
 .||| |.|. |.|.  . |..
LTNLEELWLSQNKIKKIENLDH
LRR_1 AqueK343.AA LRR_1 1062-1084 18 0.025934 12.37 Pfam 1-26 (26) Show / Hide 
Range on Protein: 1062-1084
Range on HMM: 1-26/26
Sequence Identity: 18% (5 aa)

HLTELVLDR-N--KI-KCMQENSLQHL
.|..| |.. |  .. .. ..... .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP AqueK343.AA LRR_TYP 1014-1037 29 0.112133 7.64 SMART 1-24 (24) Show / Hide 
Range on Protein: 1014-1037
Range on HMM: 1-24/24
Sequence Identity: 29% (7 aa)

MQNLQVLHLAYNGINSLVPLQLYR
. ||..|.| .| . .| |  .  
LPNLRELDLSNNQLTHLPPGAFQG
LRR_TYP AqueK343.AA LRR_TYP 1038-1059 33 0.123722 7.29 SMART 1-24 (24) Show / Hide 
Range on Protein: 1038-1059
Range on HMM: 1-24/24
Sequence Identity: 33% (8 aa)

LPGLRALFLQGNEISRI--EGLDG
|| || | |..| ....  . ..|
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 AqueK343.AA LRR_1 1108-1131 20 0.156706 9.6 Pfam 1-26 (26) Show / Hide 
Range on Protein: 1108-1131
Range on HMM: 1-26/26
Sequence Identity: 20% (6 aa)

NLERLYLGM-N--RIQDYSELEK--LGCL
||..|.|.  |  .....  . .  .  |
NLQHLDLSGCNCCNLTGH--IPPSCF-NL
LRR_TYP AqueK343.AA LRR_TYP 1084-1107 29 0.451874 2.68 SMART 1-24 (24) Show / Hide 
Range on Protein: 1084-1107
Range on HMM: 1-24/24
Sequence Identity: 29% (7 aa)

LVTLKEFHLEENRLSDLSHFESVK
|. |.| .|. |.|. | .     
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 AqueK343.AA LRR_1 1086-1106 18 0.608853 7.51 Pfam 1-26 (26) Show / Hide 
Range on Protein: 1086-1106
Range on HMM: 1-26/26
Sequence Identity: 18% (5 aa)

TLKEFHLEE-N--RLS-DLSH--FESV
.|.. .|   |  .|. ....  | . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_SD22 AqueK343.AA LRR_SD22 1060-1081 40 0.660844 3.69 SMART 1-22 (22) Show / Hide 
Range on Protein: 1060-1081
Range on HMM: 1-22/22
Sequence Identity: 40% (9 aa)

LHHLTELVLDRNKIKCMQENSL
|..|.|| |  ||||...  . 
LTNLEELWLSQNKIKKIENLDH
LRR_SD22 AqueK343.AA LRR_SD22 1014-1035 31 0.800817 3.01 SMART 1-22 (22) Show / Hide 
Range on Protein: 1014-1035
Range on HMM: 1-22/22
Sequence Identity: 31% (7 aa)

MQNLQVLHLAYNGINSLVPLQL
..||..| |  |.| ..  |  
LTNLEELWLSQNKIKKIENLDH
LRR_1 AqueK343.AA LRR_1 1016-1038 28 0.893106 6.92 Pfam 1-26 (26) Show / Hide 
Range on Protein: 1016-1038
Range on HMM: 1-26/26
Sequence Identity: 28% (8 aa)

NLQVLHLAY-N--GIN-SLVPLQ-LYRL
|||.|.| . |   .  . .|   .  |
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 AqueK343.AA LRR_1 1040-1060 25 1.11375 6.58 Pfam 1-26 (26) Show / Hide 
Range on Protein: 1040-1060
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

GLRALFLQG-N--EIS-RIEG--LDGL
 |. | |.| |   ..  |    . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_SD22 AqueK343.AA LRR_SD22 1084-1102 31 1.76597 0.21 SMART 1-22 (22) Show / Hide 
Range on Protein: 1084-1102
Range on HMM: 1-22/22
Sequence Identity: 31% (7 aa)

LVTLKEFHLEENRL---SDLSH
|  |.|. |  |..   ..|.|
LTNLEELWLSQNKIKKIENLDH
LRR_1 AqueK343.AA LRR_1 1133-1164 13 55.410944 0.56 Pfam 1-26 (26) Show / Hide 
Range on Protein: 1133-1164
Range on HMM: 1-26/26
Sequence Identity: 13% (5 aa)

YLIELSIIS-N--PISRRMQHRSLLIYKLPS--LQSL
 | .|.. . |  ....           .|.  . .|
NLQHLDLSGCNCCNLTGH----------IPPSCF-NL
EPH_lbd AqueK343.AA EPH_lbd 1267-1456 19 8.7e-08 -0.64 SMART 1-184 (184) Show / Hide 
Range on Protein: 1267-1456
Range on HMM: 1-184/184
Sequence Identity: 19% (42 aa)

ERILLDSQNYRSAFLVGAEGENRTWLTIDYDGGGVGRPGAAEFVD-TWYEGNQGVQC---LHRINVCAAL-IPGGTSSFQSNWLITQYINISEPGISQLR
| .|.|.  . .            |.| ..              . || |  .        .   || .  |.   .. |.|||.|..|.  .   ..  
EVVLMDTKTETGELG---------WTTYPP-------------HGGTWEEVSGMDEHHNPIRTYQVCNVMEIN--EPN-QNNWLRTHWIYRRG--AQRIY

VNLTFSSNLVCSSQQCGQ----QQTFEVQTFDTDKPDD---INRG-NISYYSYAGVRLIHTAEE--------GATTDSESFA-VSSSGLYLAIWDQGSCT
| | |.    |.|   .     ..|| ...  .|  .    ..      | .  ... ..   .          .|   ||  .|  |.|||  ||| | 
VELKFTM-RDCNSMPGVAGVSCKETFNLYYYESDNDHATAHTPFWMENPYIKIDTIAADESFTQRDFGDRVMKMNTEVRSFGPLSKKGFYLAFQDQGACM

VINRIVVFYNVC
 . .  |||  |
ALVSVRVFYKKC
GCC2_GCC3 AqueK343.AA GCC2_GCC3 1519-1560 33 1.3e-05 21.27 Pfam 1-45 (49) Show / Hide 
Range on Protein: 1519-1560
Range on HMM: 1-45/49
Sequence Identity: 33% (15 aa)

GYEA-NGT-VCQACEEGTYKPFAGDSDCNGCPNN-SYSASPGSVS
|.   .|.  |..|. |||.. .|   |. || . .. ..|||.|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTS
EGF_CA AqueK343.AA EGF_CA 1509-1527 39 0.001824 13.47 Pfam 26-53 (53) Show / Hide 
Range on Protein: 1509-1527
Range on HMM: 26-53/53
Sequence Identity: 39% (11 aa)

IGSASCQ---CNAGYE------ANGTVC
||| .|.   | .|||      ..||.|
IGSFECVNQDCMDGYEMISENNCDGTNC
NCD3G AqueK343.AA NCD3G 1528-1570 27 0.02047 9.14 Pfam 7-54 (54) Show / Hide 
Range on Protein: 1528-1570
Range on HMM: 7-54/54
Sequence Identity: 27% (13 aa)

QACEEGTYK-PFAGDS----DCNGCPNNSYSASPGSVSCQCLSGYYRA
. |..|..| |  |.     ||  ||...|| ...|..|.     ...
EPCPPGFRKKPQKGQHTCCWDCIPCPEGEYSNTTDSYTCTPCPEDQWP
FN3 AqueK343.AA FN3 1583-1661 24 1.1e-13 52.73 SMART 1-69 (69) Show / Hide 
Range on Protein: 1583-1661
Range on HMM: 1-69/69
Sequence Identity: 24% (23 aa)

PSSPQN---LTNTSVAET------IISISWLEPAYNGGRTDLYYVISINSSISLMEYSTVHTNYTLMGLTPF----TTYEIQVMARNG--VSDQ
|..|.|   |. |.| .|       ...|| .|        ..|.                  ||. ||.|     |.||..| |.||  .   
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Pkinase_Tyr AqueK343.AA Pkinase_Tyr 1848-2005 21 2.2e-29 100.11 Pfam 1-113 (270) Show / Hide 
Range on Protein: 1848-2005
Range on HMM: 1-113/270
Sequence Identity: 21% (36 aa)

IEIQETIGQGEFGIVYKATMK----ESQQEIALKTLKGPFSKSD--VDCLLEECLLMSNF-DNPNVLSLIGVCADLGSA--PGIIMPYMSKGSLLSYLQK
|.. ...|.|.|| |||.|.|    . ... | |.||   ....   . ...|  .|... ..||...|.||| | |    . |.|.|| .|.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

EKSYLIVEASSEESTVLNDEDQADTALLPSLTNAGQVKVMNVPLYMSTHTSRQSQAMEARALHLQTL
 .                                                      .. ..| ...|
HR------------------------------------------------------EDKQPLTMKDL
Kinase AqueK343.AA Met 1849-1935 34 2.7e-23 72.98 In-house 1-93 (271) Show / Hide 
Range on Protein: 1849-1935
Range on HMM: 1-93/271
Sequence Identity: 34% (32 aa)

EIQETIGQGEFGIVYKATMKE---SQQEIALKTLK--GPFSKSDVDCLLEECLLMSNFDNPNVLSLIGVCADLGS-APGIIMPYMSKGSLLSY
   . |||| || ||....      .  .| |.|.         .   |.| ..|. || ||||||||.| |  .  | .. ||| .| |...
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTF
Kinase AqueK343.AA TK 1848-1938 20 7.9e-23 72.68 In-house 1-152 (486) Show / Hide 
Range on Protein: 1848-1938
Range on HMM: 1-152/486
Sequence Identity: 20% (31 aa)

IEIQETIGQGEFG---IVYKATMKESQ-------------------------QEIALKTLKGPFSKSDVDCLL-------------EECLLMSNFD----
|.. ...|.|.||    |||.....                           .. | |.||   . |. . ..             ||.. |. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-NPNVLSLIGVCADLG-----------SAPGIIMPYMSKGS----LLSYLQK
  ||...|.||| . .             . |.| ||..|.    |..||.|
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRK
Kinase AqueK343.AA UTK 1848-1938 28 1.4e-22 74.11 In-house 1-103 (296) Show / Hide 
Range on Protein: 1848-1938
Range on HMM: 1-103/296
Sequence Identity: 28% (30 aa)

IEIQETIGQGEFGIVYKATMKE-----SQQEIALKTLK-GPFSKSDVD---CLLEECL---LMSNFD-NPNVLSLIGVCADLGSAPGIIMPYMSKGSLLS
... ...|||.||.|.||. ..      ..  |.|... . ..  . .    ..||.    .|..|.  |||| |.||| . .  . |.. ||..|.|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLQK
||..
YLRR
Kinase AqueK343.AA TKL 1854-1937 23 5.4e-21 72.33 In-house 1-130 (364) Show / Hide 
Range on Protein: 1854-1937
Range on HMM: 1-130/364
Sequence Identity: 23% (30 aa)

IGQGEFGIVYKATMKESQ--------QEIALKTLKG----PFSKSDVD---------------------CLLEECL-LMSNFDNPNVLSLIGVCADLGSA
||.| ||.|||.. .           ...| |..|      |.|.. .                       .|| . .||... ||.....|.| . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PGIIMPYMSKGSLLSYLQ
            ..|.| |...||||.||.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH
Kinase AqueK343.AA TK-Unique 1848-1938 28 4.4e-20 66.04 In-house 1-98 (294) Show / Hide 
Range on Protein: 1848-1938
Range on HMM: 1-98/294
Sequence Identity: 28% (28 aa)

IEIQETIGQGEFGIVYKATMK------ESQQEIALKTLKGPFSKSDVDCLLEECLLMSNFD-NPNVLSLIGVCADLGSAPGIIMPYMSKGSLLSYLQK
.|....||.|.|| |......      . |. .|.|.|| .... |.. .| |  .|.. .  ||.....|.| . .  . |||.|...|.|..||..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRT
Kinase AqueK343.AA Pkinase 1848-1942 25 8.5e-16 56.94 Pfam 1-103 (293) Show / Hide 
Range on Protein: 1848-1942
Range on HMM: 1-103/293
Sequence Identity: 25% (27 aa)

IEIQETIGQGEFGIVYKATMKESQQEIALKTLKGPFSKSDVDCLLE---ECLLMSNFDNPNVLSLIGVCADLGSAPGIIMPYMSKG----SLLSYLQ--K
..| ..||.| || |||.. | .... |.|..| .  ||..|  .    |. .| ... ||.. |.... | .. . ..|.|. .|    .| .|..  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

EKSY
....
HGCF
Kinase AqueK343.AA MLK 1848-1941 28 1.3e-15 50.7 In-house 1-106 (291) Show / Hide 
Range on Protein: 1848-1941
Range on HMM: 1-106/291
Sequence Identity: 28% (30 aa)

IEIQETIGQGEFGIVYKATMKESQ---QEIALKTLK-GPFSKSD----VDCLLEECLLMSNFDNPN----VLSLIGVCADLGSAPGIIMPYMSKGSLLSY
|...| || | || |.|....       ..|.|  .  .|.|||     . . .|| . . .. ||    .  . |||.. ..  .|.| |...||| ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LQKEKS
|  ..|
LHGARS
Kinase AqueK343.AA Axl 1848-1936 31 1.9e-15 50.98 In-house 1-98 (267) Show / Hide 
Range on Protein: 1848-1936
Range on HMM: 1-98/267
Sequence Identity: 31% (31 aa)

IEIQETIGQGEFGIVYKATMKESQ---QEIALKTLK-GPFSKSDVDCLLEECLLMSNFDNPNVLSLIGVCADLGS-----APGIIMPYMSKGSLLSYL
. .  ..|.|||| |  . .|      . .| |..|   ...|...  | |   | .|| |||. |||||  . .     .| .|.|.|  | | ..|
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFL
Kinase AqueK343.AA Fer 1848-1941 30 8.5e-15 46.93 In-house 1-105 (283) Show / Hide 
Range on Protein: 1848-1941
Range on HMM: 1-105/283
Sequence Identity: 30% (32 aa)

IEIQETIGQGEFGIVYKA--TMKESQQ--------EIALKTLKGPFSKSD-VDCLLEECLLMSN-FDNPNVLSLIGVCADLGSAPGIIMPYMSKGSLLSY
..... .| | ||.|||.  |.|.  .        ... |..|. ... .    .. |  .| | .| |||  ..|||.|   .  |.| ... |||.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDE-QPIMIVMEFCNGGSLDSY

LQKEKS
|.|.|.
LKKNKN
Kinase AqueK343.AA Eph 1848-1939 34 1.1e-14 45.58 In-house 1-98 (264) Show / Hide 
Range on Protein: 1848-1939
Range on HMM: 1-98/264
Sequence Identity: 34% (34 aa)

IEIQETIGQGEFGIVYKATMKES--QQEI-----ALKTLKGPFSKSDVDCLLEECLLMSNFDNPNVLSLIGVCADLGSAPGIIMPYMSKGSLLSYLQKE
| |.. || |||| |.. ..| .  ..|.     | ||||   . ..    | |  .|  || ||.. | || .    .  |.  ||  ||| |.| ..
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPV-MIVTEYMENGSLDSFLRQH
Kinase AqueK343.AA Abl 1848-1938 32 1e-13 41.65 In-house 1-88 (252) Show / Hide 
Range on Protein: 1848-1938
Range on HMM: 1-88/252
Sequence Identity: 32% (30 aa)

IEIQETIGQGEFGIVYKATMKESQQEIALKTLKGPFSKSDVDCLLEECLLMSNFDNPNVLSLIGVCADLGSAPGIIMPYMSKGSLLSYLQK
| ... .| | .| ||..  |  .. .| ||||      .|.  |.|  .| .   ||.  |.|||    .   ||  .|..| || || .
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKE--DTMEVHEFLKEAAIMKEMKHPNLVQLLGVCT-REPPFYIITEFMCYGNLLDYLRE
Kinase AqueK343.AA TyrKc 1848-2059 16 2.8e-08 -88.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 1848-2059
Range on HMM: 1-280/280
Sequence Identity: 16% (50 aa)

IEIQETIGQGEFGIVYKATMKESQQEIALKTLKGPFSKSDVDCLLEECLLMSNF--DNPNVLSLIGVCADLG------SAPGIIMPYMSKGSLLSYLQKE
|.  ...| |.||.|||.|.|   .. | |.||       .  ...|  .|...  ..||.. |.||| . |        . |.| ||..|.|..||.| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KSYLIVEASSEESTVLNDEDQADTAL--------LPS--------------LTNAGQVKV----MNVPLYMS--------THTSRQ-SQAM---------
.              |. .|  . ..        | |              ... ..||.    .   .|          . .... ...          
RPK------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

-EARALHLQTLQ----------------AFQDRSLSFFQCVSSQSVAPDDADPHCSDIPIRN-----VTFPNERILL-------------DSQNYRSTL
 |.   .  | .                  |  .   .| .| | |  .  . .  ..|  .     |. | |   .               .. .. .
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK343.AA S_TKc 1848-2016 13 4.1e-07 -72.6 SMART 1-231 (231) Show / Hide 
Range on Protein: 1848-2016
Range on HMM: 1-231/231
Sequence Identity: 13% (35 aa)

IEIQETIGQGEFGIVYKATMKESQQEIALKTLKGPFSKSDVDCLLEECLLMSNFDNPNVLSLIGVCADLGSAPGIIMPYMSK--GSLLSYLQKEKS----
 || ..||.| || |||.. |..... |.| .|        . .. |  .... . ||.  |..|. |  .   ..| |..   |.|..|..| ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YLIVEASS--------------------------------------------------------EESTVLNDEDQADT----------------ALLP
  .   .| .                                                        |         . ..                .  |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCGYP

SLTNAGQVKVMNVPLYMSTHTSRQSQAMEARALHLQTLQ--------AFQDRS-------LSFF
      . ..... .             ||. .  . ||        | .            .|
PFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
GCC2_GCC3 AqueK343.AA GCC2_GCC3 2298-2339 35 6.6e-07 25.42 Pfam 1-45 (49) Show / Hide 
Range on Protein: 2298-2339
Range on HMM: 1-45/49
Sequence Identity: 35% (16 aa)

GYEA-NGT-VCEACQEGTYKPFAGDSECKDCPEN-SYSASPGSVS
|.   .|.  ||.|  |||.. .|  .|. || . .. ..|||.|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTS
NCD3G AqueK343.AA NCD3G 2307-2349 31 0.00073 13.44 Pfam 7-54 (54) Show / Hide 
Range on Protein: 2307-2349
Range on HMM: 7-54/54
Sequence Identity: 31% (15 aa)

EACQEGTYK-PFAGDS----ECKDCPENSYSASPGSVSCQCLPGYYRT
| |..|..| |  |.     .| .|||..|| ...|..|.  |  .. 
EPCPPGFRKKPQKGQHTCCWDCIPCPEGEYSNTTDSYTCTPCPEDQWP
EGF_CA AqueK343.AA EGF_CA 2288-2306 35 0.003276 12.67 Pfam 26-53 (53) Show / Hide 
Range on Protein: 2288-2306
Range on HMM: 26-53/53
Sequence Identity: 35% (10 aa)

DGSASCQ---CNAGYE------ANGTVC
.|| .|.   | .|||      ..||.|
IGSFECVNQDCMDGYEMISENNCDGTNC