Gene AqueK342 (A.queenslandica)

AqueK342

Species: A.queenslandica
Alias: AqueK342
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK342.AA Protein None 417 None Fasta, JSON
AqueK342.kin_dom Protein Kinase Domain None 93 None Fasta, JSON

Protein domain

Protein domains of AqueK342.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SR AqueK342.AA SR 23-165 33 4.8e-43 150.23 SMART 1-118 (118) Show / Hide 
Range on Protein: 23-165
Range on HMM: 1-118/118
Sequence Identity: 33% (53 aa)

LQLVNGDVPEQGRVEICING----TWGTVCDDHWNHSNAQVVCRQLGYLNAGTPDQGRVEICINGTWGTVCDDDWNHSNAQVVCRQLGYLNAVPEYYS--
. ||.|. | .||||. .||    .|||||||.|                                         .  .|.|||||||. .||  . .  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNW-----------------------------------------DIRDANVVCRQLGCGGAVSASQTLP

--RAYFGAGTGKIFLDDVRCAGNESSLLECMHNPIGSHN--CDH------SKDVGVSCI
  .|.||.|.| | .|.||| |.|.|| .|.|...|.||  |.|      . |.|| | 
ATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNCCSHNHHRNRQEDAGVVCS
SRCR AqueK342.AA SRCR 74-165 51 1e-42 145.28 Pfam 8-112 (112) Show / Hide 
Range on Protein: 74-165
Range on HMM: 8-112/112
Sequence Identity: 51% (54 aa)

QGRVEICI-NGTWGTVCDD-D-WNHSNAQVVCRQLGY-LNAVPEYYSRAY--FG--AGTGKIFLDDVRCAGNESSLLECMHNPIGS--HN--CDHS-KDV
.||||..  ||.||||||| . |.  .|.|||||||.  .||  . ..||  ||  .||| | .|.||| |||.|| .| | | |   ||  |.||  |.
EGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMCSHSREDA

GVSCI
|| | 
GVICS
SRCR AqueK342.AA SRCR 26-69 54 1.2e-20 71.21 Pfam 1-48 (112) Show / Hide 
Range on Protein: 26-69
Range on HMM: 1-48/112
Sequence Identity: 54% (26 aa)

VNGDVPEQGRVEICI-NGTWGTVCDD-H-WNHSNAQVVCRQLGY-LNA
|.|..| .||||..  ||.||||||| . |.  .|.|||||||.  .|
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGA
Kinase AqueK342.AA Pkinase_Tyr 305-400 48 5.7e-48 163.08 Pfam 175-270 (270) Show / Hide 
Range on Protein: 305-400
Range on HMM: 175-270/270
Sequence Identity: 48% (48 aa)

KLPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTP-YPGLDPSGLVELL-DNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
||||||||.|.|..|.|..||||||.|||.||.|..|..| |||.... ..|.. ..|.|. .|.|   ..||| || .|||.  ..|| |||..|  
KLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
SR AqueK342.AA SR 172-275 40 3.3e-44 154.11 SMART 1-118 (118) Show / Hide 
Range on Protein: 172-275
Range on HMM: 1-118/118
Sequence Identity: 40% (48 aa)

LRLVNGSTPVEGRVEICITY----MWGTVCDDLWTNVNAEVVCTQLGYPTTGAVYRH----MAYFGEGRGTIYLDDVKCNGSESSLLSCSHLSSDDHS-V
.|||.|..| |||||. .       ||||||| |.  .|.||| |||...  ....      |.||.|.| |..|.| |.|.|.||  |.| .   |. .
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

DCYH------HEDVGVICN
 | |      .||.||.|.
-CSHNHHRNRQEDAGVVCS
Kinase AqueK342.AA TK 305-400 33 8e-44 144.32 In-house 346-486 (486) Show / Hide 
Range on Protein: 305-400
Range on HMM: 346-486/486
Sequence Identity: 33% (47 aa)

KLPIKWMALESIHDGV---------FSEKSDVWSYGVLCWEVFSLGKTPYPG-LDP---------SGLVELLDNGGR------------LQPPQ-NGASS
||||.||| |.. |.|         |..||||||.|||.||.|..|..||.| ..            ..|.| .|||            ...||  ....
KLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPD

-------------QEIYALMVSCWHESSSNRPLFSELVESV
             .|.| || .|||.  . || ||.|.|  
WMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK342.AA FGFR 306-400 47 1.5e-42 142.79 In-house 200-293 (293) Show / Hide 
Range on Protein: 306-400
Range on HMM: 200-293/293
Sequence Identity: 47% (46 aa)

LPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLD-PSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
|||||||.|.  | |.  .||||||||| ||.. .| .|||.      | ..|  | |. .|.|   ||||| .| .|||.... || | .|||. 
LPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
SRCR AqueK342.AA SRCR 175-275 43 9.3e-40 135.36 Pfam 1-112 (112) Show / Hide 
Range on Protein: 175-275
Range on HMM: 1-112/112
Sequence Identity: 43% (49 aa)

VNGSTPVEGRVEICI-TYMWGTVCDD-L-WTNVNAEVVCTQLGY-PTTGAVYRHMAY--FG--EGRGTIYLDDVKCNGSESSLLSCSHLSSDDHSVD--C
|.||.| |||||..     |||||||   |.. .|.||| |||. ..   .. . ||  ||  .|.| |..|.| |.|.|.|| .|.| .. .|. .  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

YHH-EDVGVICN
 |. ||.||||.
SHSREDAGVICS
Kinase AqueK342.AA VEGFR 305-400 50 4.4e-39 136.16 In-house 238-332 (332) Show / Hide 
Range on Protein: 305-400
Range on HMM: 238-332/332
Sequence Identity: 50% (49 aa)

KLPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLD-PSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
.|||||||.||| | |.. .||||||||. ||.||||. |||| .    .   | .| |.  |    . .|||  | .|||.    ||.||||||  
RLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPD--YCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase AqueK342.AA TK-Unique 305-400 41 6.8e-39 131.77 In-house 197-294 (294) Show / Hide 
Range on Protein: 305-400
Range on HMM: 197-294/294
Sequence Identity: 41% (41 aa)

KLPIKWMALESIH--DGVF-SEKSDVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGAS-SQEIYALMVSCWHESSSNRPLFSELVESV
..||.|||.||.   .|.. ..||||||.||| ||.|.||..||||.... ..|.. .| |.. |..  . |.|.| || |||... . || |....   
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK342.AA UTK 305-400 40 4.4e-38 127.86 In-house 200-296 (296) Show / Hide 
Range on Protein: 305-400
Range on HMM: 200-296/296
Sequence Identity: 40% (39 aa)

KLPIKWMALESIHDG-VFSEKSDVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
..||.||| |.. ..  |..||||||.||.|||... |..||||.    ... . ||||...|.. . . ..| ||..||| . ..|| | .||. .
RWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK342.AA KIN6 305-400 44 4.8e-38 123.19 In-house 210-305 (305) Show / Hide 
Range on Protein: 305-400
Range on HMM: 210-305/305
Sequence Identity: 44% (44 aa)

K-LPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLD-PSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
. |||||||.|..    || ||||||.||| .|.||||  |||..  |  . | .  |.|.. | .   . |||  | ||| | .. || |.|.    
RYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW--CPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase AqueK342.AA EGFR 305-401 44 2.8e-36 117.82 In-house 164-258 (258) Show / Hide 
Range on Protein: 305-401
Range on HMM: 164-258/258
Sequence Identity: 44% (43 aa)

KLPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESVN
|.||||||||.|| ...  .|||||||| |||.   |. || |.  .   .||..| ||. |..   .. .| .||.||.  .  || | ||.|  .
KMPIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFGQKPYDGIPAREIPDLLEKGERLPQPPI--CTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase AqueK342.AA ALK 306-402 44 3e-34 115.64 In-house 179-273 (273) Show / Hide 
Range on Protein: 306-402
Range on HMM: 179-273/273
Sequence Identity: 44% (43 aa)

LPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESVNL
.|.|||  |   ||.|  |.||||.||||||.||||  ||||       |..  |||. ||.|    | .| .|  ||      || |  ..|.   
MPVKWMPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRNCP--QPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase AqueK342.AA RTKB 305-400 42 3.7e-34 112.56 In-house 170-264 (264) Show / Hide 
Range on Protein: 305-400
Range on HMM: 170-264/264
Sequence Identity: 42% (41 aa)

KLPIKWMALESIHDGVFSEKS-DVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
.||||||| ||. .  .. || ||||.|| .||.|||| |||. .    . ..|  | ||  |.    .|.....|  || .  ..|| |.|||.. 
RLPIKWMAPESWAHRIYTTKSGDVWSFGVTMWEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPR--QMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase AqueK342.AA HMTK 304-399 38 5.5e-33 112.41 In-house 192-291 (291) Show / Hide 
Range on Protein: 304-399
Range on HMM: 192-291/291
Sequence Identity: 38% (38 aa)

VKLPIKWMALESIH--DGVFSEKSDVWSYGVLCWEVFSLGKTPYP--GLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVES
||||||||| |     ...||||||||..||..||... | .||.  ..        .  |.||  |. .. . ....|| .|||   ..|| |..|  .
VKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM
TyrKc AqueK342.AA TyrKc 183-400 21 3e-14 7.72 SMART 13-280 (280) Show / Hide 
Range on Protein: 183-400
Range on HMM: 13-280/280
Sequence Identity: 21% (63 aa)

GRVEICITYMWGTVCD------------------DLWTNV--NAEVVCTQLGYPTT--------GAVYRHMAYFGEGRGTIYLDDVKCNGSESSLLSCSH
|.|  .. .      .                   . ...  . . .   .|. |.        . ..  | |   |    || . . .           
GEVYKGTWK-----IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-----------

LSSDDHSVDCYHHEDVGVICNDI---------------D-------VSCNETVC------STKLDNA-VW----REMSDSG--PVK--LPIKWMALESIH
            ..|   .| .|               |       |. | ||       | ....   .       . ..    |  |||.|||.|.| 
----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

DGVFSEKSDVWSYGVLCWEVFSLGKTPYPG-----LDPSGLVELLDNGGRLQPPQNGA------SSQEIYALMVSCWHESSSNRPLFSELVESV
.|.|..||||||.||..||.|..|..||||     .... ..|....|.|. .|.|.        ..|.| .| .||||  ..|| |||..|  
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK342.AA Pkinase 322-400 13 9.4e-08 28.5 Pfam 190-293 (293) Show / Hide 
Range on Protein: 322-400
Range on HMM: 190-293/293
Sequence Identity: 13% (14 aa)

SEKSDVWSYGVLCWEVFSLGKTPYPGL----DPSGLVELLDNGGRLQPPQNGASS---------------------QEIYALMVSCWHESSSNRPLFSEL
. |.|.||.|....|... |..|.||     .     ..... .. ... .   .                     .|   .. .|..   . || . ..
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

VES--V
...  .
LQHPWF