Gene AqueK341 (A.queenslandica)

AqueK341

Species: A.queenslandica
Alias: AqueK341
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK341.AA Protein None 92 None Fasta, JSON
AqueK341.kin_dom Protein Kinase Domain None 92 None Fasta, JSON

Protein domain

Protein domains of AqueK341.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK341.AA Pkinase_Tyr 1-92 40 6e-36 122.38 Pfam 44-143 (270) Show / Hide 
Range on Protein: 1-92
Range on HMM: 44-143/270
Sequence Identity: 40% (41 aa)

D--IDSLLDECIIMMSF-DNLNVLPLIGVCLDLGPA--PYIIMPFMSRGSLLSYLEE----DIILNVRKLLLSICLQVAKGMSYLASHRFIHRDLAARNC
.  ..... |  ||... .. |.. |.|||.| |    .||.|..|  |.||.|| .    .  |..   ||..|.|.||||.||.|...||||||||||
QNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNC

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Kinase AqueK341.AA Met 6-92 46 5.3e-31 98.65 In-house 49-136 (271) Show / Hide 
Range on Protein: 6-92
Range on HMM: 49-136/271
Sequence Identity: 46% (41 aa)

LDECIIMMSFDNLNVLPLIGVCLDLGP-APYIIMPFMSRGSLLSYLEEDIILNVRKLLLSICLQVAKGMSYLASHRFIHRDLAARNCM
| | |.|  ||  ||| |||.|||     |... |.|  | |... .        . |.. |.||||||.|.|| .|.|||||.||||
LREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNNPCVRDLIEFCHQVAKGMMYMASQKFVHRDLACRNCM
Kinase AqueK341.AA UTK 5-91 36 2.4e-27 90.61 In-house 53-149 (296) Show / Hide 
Range on Protein: 5-91
Range on HMM: 53-149/296
Sequence Identity: 36% (36 aa)

LLDECI---IMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLE--------EDIILNVRKLLLSICLQVAKGMSYLASHRFIHRDLAARNC
.. |.    .|. |.   ||| |.|||.. .| ..|.. .|..|.|.|||         .. .|. ...|   ....| ||.||.|..|.|||||||||
FMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLC-MAWDIARGMQYLHSCGFVHRDLAARNC
Kinase AqueK341.AA TK 6-92 19 2.4e-26 84.67 In-house 86-272 (486) Show / Hide 
Range on Protein: 6-92
Range on HMM: 86-272/486
Sequence Identity: 19% (36 aa)

LDECIIMMSFD-----NLNVLPLIGVCLDLG-----------PAPYIIMPFMSRGS----LLSYLEEDIILNVR--------------------------
| |. .|. ..       |.. |.|||.. .           . ..|.| .|. |.    |..|| .                                 
LEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDIT

-----------------------------KLLLS-------------------ICLQVAKGMSYLASH------RFIHRDLAARNCM
                             | ||.                   .|.|.|.||.||.|.      .|.|||||||||.
YSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCL
Kinase AqueK341.AA Tec 25-91 47 2.7e-23 78.3 In-house 61-128 (254) Show / Hide 
Range on Protein: 25-91
Range on HMM: 61-128/254
Sequence Identity: 47% (33 aa)

GVCLDLGPAPYIIMPFMSRGSLLSYLEEDIILNVRKL--LLSICLQVAKGMSYLASHRFIHRDLAARNC
|||.   |  ||.  .|..|.||.|| |      ...  ||..|..| .|| || .| |||||||||||
GVCSQQRPI-YIVTEYMEHGCLLNYLREHKHHFQKNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNC
Kinase AqueK341.AA TK-Unique 19-92 27 1.3e-21 71.38 In-house 65-165 (294) Show / Hide 
Range on Protein: 19-92
Range on HMM: 65-165/294
Sequence Identity: 27% (28 aa)

NVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLE----------------------EDIILN--VR-KLLLSICLQVAKGMSYLAS--HRFIHRDLAARNC
|.. ..|.| . .  ..|||.....|.|..||                       .|. ..  .  |.|.... |.|.||.||||  ....||||.|||.
NIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNV

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Kinase AqueK341.AA Abl 1-92 44 7.8e-21 65.78 In-house 38-129 (252) Show / Hide 
Range on Protein: 1-92
Range on HMM: 38-129/252
Sequence Identity: 44% (41 aa)

DIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLEEDIILNVRKL-LLSICLQVAKGMSYLASHRFIHRDLAARNCM
...  | |  ||      |.  |.|||    |  |||  ||. | || || |    ..  . || .  |.| ||||| .. |||||||||||.
EVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPF-YIITEFMCYGNLLDYLRECDREELPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCL
Kinase AqueK341.AA EGFR 3-92 38 1.9e-19 61.04 In-house 46-133 (258) Show / Hide 
Range on Protein: 3-92
Range on HMM: 46-133/258
Sequence Identity: 38% (35 aa)

DSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLEEDIILNVRKLLLSICLQVAKGMSYLASHRFIHRDLAARNCM
. .|||  .| | |. ... |.|||.       ..  .|  |.|| |. .       ..||  |.|.||||.||  || .|||||||| .
EEMLDEAYVMASVDHPHLVRLLGVCMHSQ--MQLVTQYMPYGCLLDYVRQHKDNIGSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVL
Kinase AqueK341.AA Axl 1-92 39 2e-19 65.32 In-house 44-145 (267) Show / Hide 
Range on Protein: 1-92
Range on HMM: 44-145/267
Sequence Identity: 39% (40 aa)

DIDSLLDECIIMMSFDNLNVLPLIGVCLDLG-----PAPYIIMPFMSRGSLLSYL-----EEDIILNVRKLLLSICLQVAKGMSYLASHRFIHRDLAARN
.|.  | | . |  ||  ||. |||||. .      |.| .|.|||  | | ..|     ... .    . |.   . .| || ||....||||||||||
EIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLYSRLGDQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARN

CM
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CM
Kinase AqueK341.AA Csk 2-90 39 4.6e-19 61.72 In-house 38-127 (251) Show / Hide 
Range on Protein: 2-90
Range on HMM: 38-127/251
Sequence Identity: 39% (36 aa)

IDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYL---EEDIILNVRKLLLSICLQVAKGMSYLASHRFIHRDLAARN
....|.|  .|      |   |||| |. .   ||.| .||.|.|. ||   .. .|   |. ||   . |..|| || .  |.||||||||
AQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLRSRGRHVI--TRRQLLKFAMDVCEGMCYLEQKKFVHRDLAARN
Kinase AqueK341.AA Src 5-90 42 5.4e-18 57.69 In-house 41-127 (255) Show / Hide 
Range on Protein: 5-90
Range on HMM: 41-127/255
Sequence Identity: 42% (38 aa)

LLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLE---EDIILNVRKLLLSICLQVAKGMSYLASHRFIHRDLAARN
.| |  || ...  ... |  || .  |  ||.  .||.|||| ||    |   |.... |...  |||.||.|| | ..|||||||||
FLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKKDGEGRHLHLPQ-LIDMAAQVAEGMAYLESMNYIHRDLAARN
Kinase AqueK341.AA Pkinase 19-86 22 1.6e-08 31.18 Pfam 61-134 (293) Show / Hide 
Range on Protein: 19-86
Range on HMM: 61-134/293
Sequence Identity: 22% (17 aa)

NVLPLIGVCLDLGPAPYIIMPFMSRG----SLLSYLE--EDIIL--NVRKLLLSICLQVAKGMSYLASHRFIHRDL
|.. |.... | .. .|..|...  |    .| .|..  ..  .     . . ....|...|. |. |...|||||
NIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDL
Kinase AqueK341.AA TyrKc 2-92 13 7.3e-05 -144.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-92
Range on HMM: 1-280/280
Sequence Identity: 13% (39 aa)

I---------------------------------DSLLDECIIMMSF--DNLNVLPLIGVCLDLG------PAPYIIMPFMSRGSLLSYLEEDII-LNVR
|                                   ...|  ||...  .. |.. |.|||.. |      . ..|.| .|. |.|..|| .    |...
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

KLLLSICLQVAKGMSYLASHRFIHRDLAARNC--------------------------------------------------------------------
. |||.|.|.|.||.||.|...||||||||||                                                                    
D-LLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF

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GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF