Gene AqueK337 (A.queenslandica)
AqueK337
Species: A.queenslandica
Alias: AqueK337
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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AqueK337.AA | Protein | None | 360 | None | Fasta, JSON |
AqueK337.kin_dom | Protein Kinase Domain | None | 80 | None | Fasta, JSON |
Protein domains of AqueK337.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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SR | AqueK337.AA | SR | 1-97 | 47 | 3.9e-47 | 163.81 | SMART | 2-118 (118) | Show / Hide |
Range on Protein: 1-97 Range on HMM: 2-118/118 Sequence Identity: 47% (55 aa) RLVNGANSNEGRIELCHNG----RWGTVCSHSWDNTDASVVCRQLGYGPGIAFY------DAYFGQGTGSIVMNDVRCNGTESYLTNCTH--TMYHN--C |||.| |..||| | ||| .|||||. .|| .||.|||||||.| ... . .|.||||.| |.| .|||.|||. |..|.| || | RLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNCC DH------FDDAGVRCA .| ||||.| SHNHHRNRQEDAGVVCS |
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SRCR | AqueK337.AA | SRCR | 3-97 | 45 | 1.9e-43 | 147.78 | Pfam | 1-112 (112) | Show / Hide |
Range on Protein: 3-97 Range on HMM: 1-112/112 Sequence Identity: 45% (51 aa) VNGANSNEGRIELCH-NGRWGTVCSH-S-WDNTDASVVCRQLGYGPG---IAFYDAY--FG--QGTGSIVMNDVRCNGTESYLTNC--THTMY--HN--C |.|....|||.|... ||.|||||.. . ||..||.|||||||.|.| . || || .||| |.|..|||.|.|. |..| ... || | VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC DHF-DDAGVRCA .| ||||.|. SHSREDAGVICS |
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SR | AqueK337.AA | SR | 104-201 | 45 | 7.9e-39 | 136.24 | SMART | 1-118 (118) | Show / Hide |
Range on Protein: 104-201 Range on HMM: 1-118/118 Sequence Identity: 45% (54 aa) IQLIGGSHHWEGRVEVCNNG----LWGTVCDNNWGSTDAAVVCRQLGWGTSGSPLS-----FAYFSQGAV-IHLDNVQCLGTEQLLTNCTH--STTHN-- . | ||... |||||| || ||||||.||. .|| ||||||| |. | . |.|.||. |..|||.| |||. |..|.| || VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC CGH------SKDAGVACH |.| . |||| | CSHNHHRNRQEDAGVVCS |
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SRCR | AqueK337.AA | SRCR | 107-201 | 43 | 5.3e-37 | 126.12 | Pfam | 1-112 (112) | Show / Hide |
Range on Protein: 107-201 Range on HMM: 1-112/112 Sequence Identity: 43% (49 aa) IGGSHHWEGRVEVCN-NGLWGTVCDN-N-WGSTDAAVVCRQLG--WGTSGSPLSFAY------FSQGAVIHLDNVQCLGTEQLLTNC--THSTT--HN-- .|||.. ||||||. || ||||||. . |. .|| ||||||| .| . .. . || .. . |..|||.| |.|. |..| .... || VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPG-TGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPM CGHS-KDAGVACH |.|| |||| | CSHSREDAGVICS |
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Pkinase_Tyr | AqueK337.AA | Pkinase_Tyr | 256-353 | 42 | 4.2e-36 | 122.9 | Pfam | 144-240 (270) | Show / Hide |
Range on Protein: 256-353 Range on HMM: 144-240/270 Sequence Identity: 42% (42 aa) IDSDGIIKVADFGLSEDIYDQNYFRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVP-YPGLDPVGVVELL-DAGGRLQNPNN .......|..||||. |||. | .. .... || |||| |.|..| |..||||||.|||.||.| .|. | |||... |.|.. . |.|. | | VTENNVVKICDFGLARDIYNDDYY--YRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN |
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Kinase | AqueK337.AA | TK | 256-357 | 26 | 1.2e-34 | 113.04 | In-house | 273-444 (486) | Show / Hide |
Range on Protein: 256-357 Range on HMM: 273-444/486 Sequence Identity: 26% (45 aa) IDSDGI-----------IKVADFG--------LSEDIY-DQNYFRQLKDSSS-------------------TIKLPLKWMAIESIHDGL---------FS ...... .|.|||| |. ||| |..| |. . . |||..||| |.. |. |. VGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFT EKSDVWSYGVLCWEVFNLGRVPYPGLDPV----------GVVELLDAGGR------------LQNPNNEACS .||||||.|||.||.| .|..||.| . |.|.| .||| .. | . |. TKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCP |
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Kinase | AqueK337.AA | TK-Unique | 256-353 | 36 | 5.2e-31 | 104.22 | In-house | 166-263 (294) | Show / Hide |
Range on Protein: 256-353 Range on HMM: 166-263/294 Sequence Identity: 36% (37 aa) IDSDGIIKVADFGLSEDIYDQNYFRQLKDSSSTIKLPLKWMAIESIH--DGLF-SEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPN . .|...|..|||...|.|. ... . | ..|..||| ||. .| . ..||||||.||| ||.| || ||||... ..|.. .| |.. |. LTEDKVCKICDFGMARDVYT---NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPE N . H |
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Kinase | AqueK337.AA | VEGFR | 256-335 | 42 | 1.8e-29 | 104.24 | In-house | 206-283 (332) | Show / Hide |
Range on Protein: 256-335 Range on HMM: 206-283/332 Sequence Identity: 42% (36 aa) IDSDGIIKVADFGLSED-IYDQ-NYFRQLKDSSSTI--KLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDP .... ..| ||||. . ||. .| |. . .||.||||.||| | .. .||||||||. ||.| || .|||| .. LCENNVVKICDFGLARHGIYKDPDYVRK------GDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPGVQI |
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Kinase | AqueK337.AA | ALK | 261-353 | 45 | 2e-29 | 98.71 | In-house | 152-241 (273) | Show / Hide |
Range on Protein: 261-353 Range on HMM: 152-241/273 Sequence Identity: 45% (43 aa) IIKVADFGLSEDI-YDQNYFRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPNN . |.|||| . || | |.| .. .| ||| | ||.| |.||||.||||||.| ||..|||| | |.. .|||. | | VAKIADFGMARDITYRADYYRK---GGRAM-MPVKWMPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN |
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Kinase | AqueK337.AA | UTK | 256-357 | 29 | 2.7e-29 | 97.37 | In-house | 151-268 (296) | Show / Hide |
Range on Protein: 256-357 Range on HMM: 151-268/296 Sequence Identity: 29% (36 aa) IDSDG-------IIKVADFG---LSEDIY---------DQNYFRQLKDSSSTIKLPLKWMAIESIHDG-LFSEKSDVWSYGVLCWEVFNLGRVPYPGLDP ..... ..|.|||| .| ... ...|... .. ..|..||| |.. .. |..||||||.||.|||.. ||.||||. VHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA----QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSN VGVVELLDAGGRLQNPNNEACS . |.. . .|||.. | ...|. MQVWHQVCNGGRYRMPCPWDCP |
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Kinase | AqueK337.AA | KIN6 | 263-353 | 41 | 5.8e-29 | 92.7 | In-house | 187-275 (305) | Show / Hide |
Range on Protein: 263-353 Range on HMM: 187-275/305 Sequence Identity: 41% (39 aa) KVADFGLSEDIYDQNYFRQLKDSSSTIK-LPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLD-PVGVVELLDAGGRLQNPNN |. |||| .|. |. | . ||.|||| |.. || ||||||.||| .|.| || ||||.. |. . | . .|.|.. | . KISDFGLCRYPYMD----QFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW |
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Kinase | AqueK337.AA | HMTK | 261-360 | 36 | 2e-27 | 92.76 | In-house | 166-267 (291) | Show / Hide |
Range on Protein: 261-360 Range on HMM: 166-267/291 Sequence Identity: 36% (38 aa) IIKVADFGLSEDIY-DQNYFRQLKDSSSTIKLPLKWMAIESIH--DGLFSEKSDVWSYGVLCWEVFNLGRVPYP--GLDPVGVVELLDAGGRLQNPNNEA ..|.|||||. . .|.|... | . .|||.||||.| .. ||||||||..||..||.. |..||. .. | . .|.|| |. . QVKIADFGLTRRLDPGQDYWHLRKHM---VKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDD CSQKM |. .. CPDDF |
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Kinase | AqueK337.AA | Ret | 261-360 | 47 | 4.8e-27 | 89.39 | In-house | 173-266 (293) | Show / Hide |
Range on Protein: 261-360 Range on HMM: 173-266/293 Sequence Identity: 47% (48 aa) IIKVADFGLSEDIY-DQNYFRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPNNEACSQK |.|. ||||. |.| | | .. || ..| ||||||| | . ||||||.||||||. .| |||| | .|| | | | | || ICKISDFGLTRDVYEDDSYVKRSKD-----RIPVKWMAIESLYDHVYTTKSDVWSFGVLCWEIVTMGANPYPGIPPERLWQLLKTGYRMDRPEN--CSEE M | M |
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Kinase | AqueK337.AA | Src-Unclassified | 261-356 | 41 | 5.6e-27 | 89.51 | In-house | 162-254 (284) | Show / Hide |
Range on Protein: 261-356 Range on HMM: 162-254/284 Sequence Identity: 41% (41 aa) IIKVADFGLS--EDIYDQNYFRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPNNEAC . ||.|||| .. | || ... ..| |||| | . | || ||||||||.| ||.. .|..|||| . .|.| . | |. | |. | VVKVCDFGLARKKLMQDDNYCMR-TGA----MFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYC |
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Kinase | AqueK337.AA | Src | 261-353 | 42 | 2.1e-26 | 86.7 | In-house | 135-224 (255) | Show / Hide |
Range on Protein: 261-353 Range on HMM: 135-224/255 Sequence Identity: 42% (41 aa) IIKVADFGLSEDIY--DQNY-FRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPNN . ||||||| | | .| |. |.| ||.| | |. | |. ||||||.|.| .|.. ||||||| . |.. ...| |. .| | VCKVADFGLARLIKEDDDEYCARH------GAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN |
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SRCR | AqueK337.AA | SRCR | 211-250 | 65 | 2.5e-21 | 73.45 | Pfam | 1-43 (112) | Show / Hide |
Range on Protein: 211-250 Range on HMM: 1-43/112 Sequence Identity: 65% (28 aa) VNGSSSTEGRVELCQ-NGRWSTVCDD-S-WDNTDASVVCRQLG |.|||. |||||.. ||.| ||||| . ||..||.||||||| VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLG |
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SR | AqueK337.AA | SR | 208-320 | 30 | 1.4e-12 | 49.06 | SMART | 1-118 (118) | Show / Hide |
Range on Protein: 208-320 Range on HMM: 1-118/118 Sequence Identity: 30% (40 aa) VRLVNGSSSTEGRVELCQNG----RWSTVCDDSWDNTDASVVCRQLGLETSEIDSD-----GIIKVADFGLSEDIYDQNYFRQLKDSSSTIKLPLKWMAI ||||.|... ||||| || .| |||||.|| .||.|||||||. . | . . | |. | . . | | VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSG---PIWMDNVRCTGTET-SLWDCPH----- ESIHDGL--FSE------KSDVWSYGVLCW .... | . |. || | WGWGQHNNCCSHNHHRNRQEDA---GVVCS |
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TyrKc | AqueK337.AA | TyrKc | 167-360 | 19 | 7.8e-12 | -31.36 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 167-360 Range on HMM: 1-280/280 Sequence Identity: 19% (59 aa) LDNVQCLGTEQ----------------LLTNCTHSTTHNCGHSKD----AGVACHV--CTPGTVRLVNGSSSTEGR-----------VELCQNGRWSTVC . . || . | ... .| | . |.. | |||. | ...|| .|.. .| ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL DDSWDNTDASVVCRQLGLETSE-------------------------------IDSDGIIKVADFGLSEDIYDQ-------NYFRQLKDSSSTIKLPLKW .. .. | ... .......|..||||| |||| | |. . ... ||..| RKHRPK-----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW MAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPG-----LDPVGVVELLDAGGRLQNPNN-------------------------------EACSQK ||.|.| .| |..||||||.||..||.| .| |||| ... |.|....|.|. | | ... .. MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC M . F |
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Kinase | AqueK337.AA | Pkinase | 256-332 | 30 | 3e-06 | 23.37 | Pfam | 141-214 (293) | Show / Hide |
Range on Protein: 256-332 Range on HMM: 141-214/293 Sequence Identity: 30% (25 aa) IDSDGII----KVADFGLSEDIYDQNYFRQLKDSSSTIKLPLKWMAIESIH-DGLFSEKSDVWSYGVLCWEVFNLGRVPYPG ||..| | |..||||.. .. . .|. . .|| | | . . |.|.||.|....|... || |.|| IDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPG |