AqueK337

Species: A.queenslandica
Alias: AqueK337
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK337.AA Protein None 360 None Fasta, JSON
AqueK337.kin_dom Protein Kinase Domain None 80 None Fasta, JSON

Protein domain

Protein domains of AqueK337.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SR AqueK337.AA SR 1-97 47 3.9e-47 163.81 SMART 2-118 (118) Show / Hide
Range on Protein: 1-97
Range on HMM: 2-118/118
Sequence Identity: 47% (55 aa)

RLVNGANSNEGRIELCHNG----RWGTVCSHSWDNTDASVVCRQLGYGPGIAFY------DAYFGQGTGSIVMNDVRCNGTESYLTNCTH--TMYHN--C
|||.| |..||| |  |||    .|||||. .|| .||.|||||||.| ... .      .|.||||.| |.| .|||.|||. |..|.|     ||  |
RLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNCC

DH------FDDAGVRCA
.|        ||||.| 
SHNHHRNRQEDAGVVCS

SRCR AqueK337.AA SRCR 3-97 45 1.9e-43 147.78 Pfam 1-112 (112) Show / Hide
Range on Protein: 3-97
Range on HMM: 1-112/112
Sequence Identity: 45% (51 aa)

VNGANSNEGRIELCH-NGRWGTVCSH-S-WDNTDASVVCRQLGYGPG---IAFYDAY--FG--QGTGSIVMNDVRCNGTESYLTNC--THTMY--HN--C
|.|....|||.|... ||.|||||.. . ||..||.|||||||.|.|     .  ||  ||  .||| |.|..|||.|.|. |..|  ...    ||  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

DHF-DDAGVRCA
.|   ||||.|.
SHSREDAGVICS

SR AqueK337.AA SR 104-201 45 7.9e-39 136.24 SMART 1-118 (118) Show / Hide
Range on Protein: 104-201
Range on HMM: 1-118/118
Sequence Identity: 45% (54 aa)

IQLIGGSHHWEGRVEVCNNG----LWGTVCDNNWGSTDAAVVCRQLGWGTSGSPLS-----FAYFSQGAV-IHLDNVQCLGTEQLLTNCTH--STTHN--
. | ||... ||||||  ||     ||||||.||. .|| ||||||| |.  |  .      |.|.||.  |..|||.| |||. |..|.|     ||  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CGH------SKDAGVACH
|.|      . |||| | 
CSHNHHRNRQEDAGVVCS

SRCR AqueK337.AA SRCR 107-201 43 5.3e-37 126.12 Pfam 1-112 (112) Show / Hide
Range on Protein: 107-201
Range on HMM: 1-112/112
Sequence Identity: 43% (49 aa)

IGGSHHWEGRVEVCN-NGLWGTVCDN-N-WGSTDAAVVCRQLG--WGTSGSPLSFAY------FSQGAVIHLDNVQCLGTEQLLTNC--THSTT--HN--
.|||.. ||||||.  || ||||||. . |. .|| |||||||  .| . .. . ||      .. .  |..|||.| |.|. |..|  ....   ||  
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPG-TGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPM

CGHS-KDAGVACH
|.||  |||| | 
CSHSREDAGVICS

Pkinase_Tyr AqueK337.AA Pkinase_Tyr 256-353 42 4.2e-36 122.9 Pfam 144-240 (270) Show / Hide
Range on Protein: 256-353
Range on HMM: 144-240/270
Sequence Identity: 42% (42 aa)

IDSDGIIKVADFGLSEDIYDQNYFRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVP-YPGLDPVGVVELL-DAGGRLQNPNN
.......|..||||. |||.  |   .. ....  || |||| |.|..| |..||||||.|||.||.| .|. | |||...  |.|.. . |.|.  | |
VTENNVVKICDFGLARDIYNDDYY--YRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN





Kinase AqueK337.AA TK 256-357 26 1.2e-34 113.04 In-house 273-444 (486) Show / Hide
Range on Protein: 256-357
Range on HMM: 273-444/486
Sequence Identity: 26% (45 aa)

IDSDGI-----------IKVADFG--------LSEDIY-DQNYFRQLKDSSS-------------------TIKLPLKWMAIESIHDGL---------FS
......           .|.||||        |. ||| |..| |.   . .                     |||..||| |.. |.          |.
VGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFT

EKSDVWSYGVLCWEVFNLGRVPYPGLDPV----------GVVELLDAGGR------------LQNPNNEACS
.||||||.|||.||.| .|..||.|  .            |.|.| .|||            .. |  . |.
TKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCP

Kinase AqueK337.AA TK-Unique 256-353 36 5.2e-31 104.22 In-house 166-263 (294) Show / Hide
Range on Protein: 256-353
Range on HMM: 166-263/294
Sequence Identity: 36% (37 aa)

IDSDGIIKVADFGLSEDIYDQNYFRQLKDSSSTIKLPLKWMAIESIH--DGLF-SEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPN
. .|...|..|||...|.|.    ...  . |  ..|..||| ||.   .| . ..||||||.||| ||.| ||  ||||...  ..|.. .| |.. |.
LTEDKVCKICDFGMARDVYT---NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPE

N
.
H

Kinase AqueK337.AA VEGFR 256-335 42 1.8e-29 104.24 In-house 206-283 (332) Show / Hide
Range on Protein: 256-335
Range on HMM: 206-283/332
Sequence Identity: 42% (36 aa)

IDSDGIIKVADFGLSED-IYDQ-NYFRQLKDSSSTI--KLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDP
.... ..|  ||||. . ||.  .| |.      .   .||.||||.||| |  .. .||||||||. ||.| || .|||| ..
LCENNVVKICDFGLARHGIYKDPDYVRK------GDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPGVQI

Kinase AqueK337.AA ALK 261-353 45 2e-29 98.71 In-house 152-241 (273) Show / Hide
Range on Protein: 261-353
Range on HMM: 152-241/273
Sequence Identity: 45% (43 aa)

IIKVADFGLSEDI-YDQNYFRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPNN
. |.|||| . || |   |.|       .. .| |||  |   ||.|  |.||||.||||||.| ||..||||     | |.. .|||.  | |
VAKIADFGMARDITYRADYYRK---GGRAM-MPVKWMPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN

Kinase AqueK337.AA UTK 256-357 29 2.7e-29 97.37 In-house 151-268 (296) Show / Hide
Range on Protein: 256-357
Range on HMM: 151-268/296
Sequence Identity: 29% (36 aa)

IDSDG-------IIKVADFG---LSEDIY---------DQNYFRQLKDSSSTIKLPLKWMAIESIHDG-LFSEKSDVWSYGVLCWEVFNLGRVPYPGLDP
.....       ..|.||||   .| ...         ...|...    ..  ..|..||| |.. ..  |..||||||.||.|||..  ||.||||.  
VHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA----QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSN

VGVVELLDAGGRLQNPNNEACS
. |.. . .|||.. | ...|.
MQVWHQVCNGGRYRMPCPWDCP

Kinase AqueK337.AA KIN6 263-353 41 5.8e-29 92.7 In-house 187-275 (305) Show / Hide
Range on Protein: 263-353
Range on HMM: 187-275/305
Sequence Identity: 41% (39 aa)

KVADFGLSEDIYDQNYFRQLKDSSSTIK-LPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLD-PVGVVELLDAGGRLQNPNN
|. ||||   .|.     |.   |   . ||.|||| |..    || ||||||.||| .|.| || ||||..  |. . | . .|.|.. | .
KISDFGLCRYPYMD----QFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW

Kinase AqueK337.AA HMTK 261-360 36 2e-27 92.76 In-house 166-267 (291) Show / Hide
Range on Protein: 261-360
Range on HMM: 166-267/291
Sequence Identity: 36% (38 aa)

IIKVADFGLSEDIY-DQNYFRQLKDSSSTIKLPLKWMAIESIH--DGLFSEKSDVWSYGVLCWEVFNLGRVPYP--GLDPVGVVELLDAGGRLQNPNNEA
..|.|||||.  .  .|.|... | .   .|||.||||.|     .. ||||||||..||..||..  |..||.  ..    |   . .|.||  |.  .
QVKIADFGLTRRLDPGQDYWHLRKHM---VKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDD

CSQKM
|. ..
CPDDF

Kinase AqueK337.AA Ret 261-360 47 4.8e-27 89.39 In-house 173-266 (293) Show / Hide
Range on Protein: 261-360
Range on HMM: 173-266/293
Sequence Identity: 47% (48 aa)

IIKVADFGLSEDIY-DQNYFRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPNNEACSQK
|.|. ||||. |.| |  | .. ||     ..| |||||||  |  .  ||||||.||||||.  .|  ||||  |    .||  | |   | |  ||  
ICKISDFGLTRDVYEDDSYVKRSKD-----RIPVKWMAIESLYDHVYTTKSDVWSFGVLCWEIVTMGANPYPGIPPERLWQLLKTGYRMDRPEN--CSEE

M
|
M

Kinase AqueK337.AA Src-Unclassified 261-356 41 5.6e-27 89.51 In-house 162-254 (284) Show / Hide
Range on Protein: 261-356
Range on HMM: 162-254/284
Sequence Identity: 41% (41 aa)

IIKVADFGLS--EDIYDQNYFRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPNNEAC
. ||.||||    .. | ||    ...    ..| |||| | .  | || ||||||||.| ||.. .|..|||| .  .|.| .  | |.  | |. |
VVKVCDFGLARKKLMQDDNYCMR-TGA----MFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYC

Kinase AqueK337.AA Src 261-353 42 2.1e-26 86.7 In-house 135-224 (255) Show / Hide
Range on Protein: 261-353
Range on HMM: 135-224/255
Sequence Identity: 42% (41 aa)

IIKVADFGLSEDIY--DQNY-FRQLKDSSSTIKLPLKWMAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPGLDPVGVVELLDAGGRLQNPNN
. |||||||   |   | .|  |.        |.| ||.| | |. | |. ||||||.|.| .|..  ||||||| .   |.. ...| |. .| |
VCKVADFGLARLIKEDDDEYCARH------GAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN

SRCR AqueK337.AA SRCR 211-250 65 2.5e-21 73.45 Pfam 1-43 (112) Show / Hide
Range on Protein: 211-250
Range on HMM: 1-43/112
Sequence Identity: 65% (28 aa)

VNGSSSTEGRVELCQ-NGRWSTVCDD-S-WDNTDASVVCRQLG
|.|||. |||||..  ||.| ||||| . ||..||.|||||||
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLG

SR AqueK337.AA SR 208-320 30 1.4e-12 49.06 SMART 1-118 (118) Show / Hide
Range on Protein: 208-320
Range on HMM: 1-118/118
Sequence Identity: 30% (40 aa)

VRLVNGSSSTEGRVELCQNG----RWSTVCDDSWDNTDASVVCRQLGLETSEIDSD-----GIIKVADFGLSEDIYDQNYFRQLKDSSSTIKLPLKWMAI
||||.|... |||||   ||    .| |||||.|| .||.|||||||. .    |      .    .  |    |.  |   .   . |    |      
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSG---PIWMDNVRCTGTET-SLWDCPH-----

ESIHDGL--FSE------KSDVWSYGVLCW
....      |       . |.   || | 
WGWGQHNNCCSHNHHRNRQEDA---GVVCS

TyrKc AqueK337.AA TyrKc 167-360 19 7.8e-12 -31.36 SMART 1-280 (280) Show / Hide
Range on Protein: 167-360
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

LDNVQCLGTEQ----------------LLTNCTHSTTHNCGHSKD----AGVACHV--CTPGTVRLVNGSSSTEGR-----------VELCQNGRWSTVC
.   . ||  .                 | ...          .|    | . |..    |  |||. |  ...||           .|.. .|      
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

DDSWDNTDASVVCRQLGLETSE-------------------------------IDSDGIIKVADFGLSEDIYDQ-------NYFRQLKDSSSTIKLPLKW
 .. ..           | ...                               .......|..||||| ||||         | |. . ...   ||..|
RKHRPK-----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MAIESIHDGLFSEKSDVWSYGVLCWEVFNLGRVPYPG-----LDPVGVVELLDAGGRLQNPNN-------------------------------EACSQK
||.|.| .| |..||||||.||..||.| .|  ||||     ...  |.|....|.|.  | |                               ... ..
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

M
.
F

Kinase AqueK337.AA Pkinase 256-332 30 3e-06 23.37 Pfam 141-214 (293) Show / Hide
Range on Protein: 256-332
Range on HMM: 141-214/293
Sequence Identity: 30% (25 aa)

IDSDGII----KVADFGLSEDIYDQNYFRQLKDSSSTIKLPLKWMAIESIH-DGLFSEKSDVWSYGVLCWEVFNLGRVPYPG
||..| |    |..||||.. ..        .   .|.   . .|| | |  .   . |.|.||.|....|... || |.||
IDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPG