Gene AqueK336 (A.queenslandica)

AqueK336

Species: A.queenslandica
Alias: AqueK336
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK336.AA Protein None 177 None Fasta, JSON
AqueK336.kin_dom Protein Kinase Domain None 80 None Fasta, JSON

Protein domain

Protein domains of AqueK336.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK336.AA Pkinase_Tyr 25-149 41 1.3e-38 131.38 Pfam 148-270 (270) Show / Hide 
Range on Protein: 25-149
Range on HMM: 148-270/270
Sequence Identity: 41% (53 aa)

GVIKVTDFGLWEEIYTKNYLKQFKESKSAKLPVKRVVLKSLHYGIFSKKSDVWSYGTLCWEAFSAGKIP-YPGMDPIALVELL-DGGQRLSCPHNKACSE
.|.|..||||   || . |   .. ....|||.|   . ...||.|. ||||||.| |.|| |. |..| ||||..  ..|.. . |.|. ||.|  |..
NVVKICDFGLARDIYNDDYY--YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPD

DIYSLMQQCWCESPDDRPLFSDLVASV
.||.||.||| . |.||| ||...   
EIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK336.AA TK 12-149 25 6.7e-37 120.69 In-house 264-486 (486) Show / Hide 
Range on Protein: 12-149
Range on HMM: 264-486/486
Sequence Identity: 25% (57 aa)

RHLSARRLLIKVHGV-----------IKVTDFG--------LWEEIYT-KNYLKQFKESK--------------------SAKLPVKRVVLKSLH-----
| | ||  |.  ..|           .|..|||        |  .||  ..| ..  ...                    ..|||..     .|      
RDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFS

----YGIFSKKSDVWSYGTLCWEAFSAGKIPYPGMDPI----------ALVELLDGGQR------------LSCPHNKACS--------------EDIYS
    ||.|. ||||||.| |.|| |. |. ||.|. .            ..|.|  |.|            . .|  . |.              |..| 
EAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYD

LMQQCWCESPDDRPLFSDLVASV
|||||| . |.||| ||.|.   
LMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK336.AA Tie 12-149 39 2.7e-34 101.28 In-house 138-267 (267) Show / Hide 
Range on Protein: 12-149
Range on HMM: 138-267/267
Sequence Identity: 39% (55 aa)

RHLSARRLLIKVHGVIKVTDFGLW--EEIYTKNYLKQFKESKSAKLPVKRVVLKSLHYGIFSKKSDVWSYGTLCWEAFSAGKIPYPGMDPIALVELLDGG
| | || .|.    | |..||||   .|.| |  .         .|||. . . || | ..  |||||||| | ||  | |  || ||    | | |  |
RDLAARNILVCENYVCKIADFGLSRGDEVYVKKTM--------GRLPVRWMAIESLNYSVYTTKSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQG

QRLSCPHNKACSEDIYSLMQQCWCESPDDRPLFSDLVASV
 |.  | |  | ...| ||.||| . | .|| |. .. ..
YRMEQPRN--CDDEVYDLMRQCWRDRPYERPPFAQIAVQL
Kinase AqueK336.AA KIN6 28-149 41 1.1e-32 105.14 In-house 187-305 (305) Show / Hide 
Range on Protein: 28-149
Range on HMM: 187-305/305
Sequence Identity: 41% (51 aa)

KVTDFGLWEEIYTKNYLKQFKESKSAK-LPVKRVVLKSLHYGIFSKKSDVWSYGTLCWEAFSAGKIPYPGMD-PIALVELLDGGQRLSCPHNKACSEDIY
|. ||||  ..|.   .     ||. . ||.|   . .|    || ||||||.| | .| || |  |||.|  |  . | . .| |.. |  | |.| ||
KISDFGLCRYPYMDQFQYT---SKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHP--KWCPEEIY

SLMQQCWCESPDDRPLFSDLVASV
  ||.|| | ||||| |...    
DIMQSCWQEKPDDRPEFNEMRMQF
Kinase AqueK336.AA Src 12-149 37 1.7e-31 104.2 In-house 121-255 (255) Show / Hide 
Range on Protein: 12-149
Range on HMM: 121-255/255
Sequence Identity: 37% (53 aa)

RHLSARRLLIKVHGVIKVTDFGLWEEIY--TKNY-LKQFKESKSAKLPVKRVVLKSLHYGIFSKKSDVWSYGTLCWEAFSAGKIPYPGMDPIALVELLDG
| | ||  |.  . | || ||||   |     .|  ..      ||.|.|      ..|| |. ||||||.| | .| .. |..|||||.    .. .. 
RDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARH-----GAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVER

GQRLSCPHNKACSEDIYS-LMQQCWCESPDDRPLFSDLVASV
| |. ||||  | . .|  .|.|||...|..|| |  |    
GYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK336.AA Syk 64-143 40 2e-31 105.44 In-house 180-257 (257) Show / Hide 
Range on Protein: 64-143
Range on HMM: 180-257/257
Sequence Identity: 40% (32 aa)

SLHYGIFSKKSDVWSYGTLCWEAFSAGKIPYPGMDPIALVELLDGGQRLSCPHNKACSEDIYSLMQQCWCESPDDRPLFS
.  |..|| ||||||.| . ||.|| |. || .|    ...... | |..||    | ...|.||..|| . . ||| |.
CIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNCP--NGCPQEMYQLMNKCWIYKWCDRPTFV
Kinase AqueK336.AA TK-Unique 12-149 33 6.5e-31 103.89 In-house 157-294 (294) Show / Hide 
Range on Protein: 12-149
Range on HMM: 157-294/294
Sequence Identity: 33% (48 aa)

RHLSARRLLIKVHGVIKVTDFGLWEEIYTKNYLKQFKESKSAKLPVKRVVLKSLH--YGIF-SKKSDVWSYGTLCWEAFSAGKIPYPGMDPIALVELLDG
|.|.||  |.  ..|.|..|||. ...||    .. .. .. ..|..   . ||   .|.. . ||||||.| | || |. |. |||||..  ..|..  
RDLCARNVLLTEDKVCKICDFGMARDVYT--NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRD

GQRLSCPHNKAC-SEDIYSLMQQCWCESPDDRPLFSDLVASV
| |.  | .  | |...|.||..||...|..|| |....   
GYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK336.AA Abl 12-149 38 1.9e-30 98.42 In-house 121-252 (252) Show / Hide 
Range on Protein: 12-149
Range on HMM: 121-252/252
Sequence Identity: 38% (53 aa)

RHLSARRLLIKVHGVIKVTDFGLWEEIYTKNYLKQFKESKSAKLPVKRVVLKSLHYGIFSKKSDVWSYGTLCWEAFSAGKIPYPGMDPIALVELLDGGQR
| | ||  |.  | ..|| ||||   .    |  .      || |.|     || |  || ||||| .| | ||    |  ||||.|     ..|. | |
RDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHA----GAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYPGIDLSHVYHKLEKGYR

LSCPHNKACSEDIYSLMQQCWCESPDDRPLFSDLVASV
.  |  . | ...| ||.|||  |. ||| | ..   .
MERP--EGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK336.AA Axl 12-147 38 3.6e-30 103.93 In-house 137-267 (267) Show / Hide 
Range on Protein: 12-147
Range on HMM: 137-267/267
Sequence Identity: 38% (52 aa)

RHLSARRLLIKVHGVIKVTDFGLWEEIYTKNYLKQFKESKSAKLPVKRVVLKSLHYGIFSKKSDVWSYGTLCWEAFSAGKIPYPGMDPIALVELLDGGQR
| | ||  ...    . | ||||   ||   | .|    . ||.||| . . ||   ..  |||||..|   ||    |. ||||..   . . | .|.|
RDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQ---GCIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHR

LSCPHNKACSEDIYSLMQQCWCESPDDRPLFSDLVA
|  |..  | ...| || |||   | ||| || |  
LKQPED--CMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase AqueK336.AA Frk 12-153 33 1.8e-29 99.1 In-house 122-260 (260) Show / Hide 
Range on Protein: 12-153
Range on HMM: 122-260/260
Sequence Identity: 33% (47 aa)

RHLSARRLLIKVHGVIKVTDFGLWEEIYTKNYLKQFKESKSAKLPVKRVVLKSLHYGIFSKKSDVWSYGTLCWEAFSAGKIPYPGMDPIALVELLDGGQR
| | || .|.  | ..|. ||||   .  |.    .     |..|.|       .|  |. ||||||.| |  |    |..|||||     .. .| | |
RDLAARNVLVGEHNICKIADFGL-ARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYR

LSCPHNKACSEDIYSLMQQCWCESPDDRPLFSDLVASVNALT
. .| |  | . .|..|..|| . |. || |  |   ..   
MPQPPN--CPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK336.AA Tec 65-151 44 5.1e-29 98.57 In-house 170-254 (254) Show / Hide 
Range on Protein: 65-151
Range on HMM: 170-254/254
Sequence Identity: 44% (39 aa)

LHYGIFSKKSDVWSYGTLCWEAFSAGKIPYPGMDPIALVELLDGGQRLSCPHNKACSEDIYSLMQQCWCESPDDRPLFSDLVASVNA
.||  .| |||||..| | || || ||.||. |. .  ||    | ||  ||   ||. ||  | .|| |.|..|| |..|  ..  
FHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPH--LCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
TyrKc AqueK336.AA TyrKc 2-149 19 1.5e-11 -35.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-149
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

IS-------------------------------------------EF-----------GSIRFE-----------------------RHLSARR------
|.                                           ..           | .. .                        .| ..|      
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

------------------------------LLIKVHGVIKVTDFGLWEEIYTK-------NYLKQFKESKSAK--LPVKRVVLKSLHYGIFSKKSDVWSY
                               |..  ...|..||||  .|| .        | .. ||.|..|  ||..   . .. ||.|. ||||||.
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRK-KEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF

GTLCWEAFSAGKIPYPG-----MDPIALVELLDGGQRLSCPHNKA------CSEDIYSLMQQCWCESPDDRPLFSDLVASV
| ..|| |. |. ||||     |... ..|... | |. .|.|        |....|..|.||| | |.||| ||...   
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK336.AA Pkinase 71-149 19 7e-06 21.94 Pfam 190-293 (293) Show / Hide 
Range on Protein: 71-149
Range on HMM: 190-293/293
Sequence Identity: 19% (21 aa)

SKKSDVWSYGTLCWEAFSAGKIPYPGM------DPIALVELLDGGQRLSCPHNKACS-------------------EDIYSLMQQCWCESPDDRPLFSDL
..|.|.||.| ...| .. |. |.||       |...... ...| .|. .  . ||                   |.  ...  |.|  | .|| . ..
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMIC-RIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

VAS--V
. .  .
LQHPWF
Kinase AqueK336.AA Tec 12-34 47 0.024474 4.07 In-house 121-143 (254) Show / Hide 
Range on Protein: 12-34
Range on HMM: 121-143/254
Sequence Identity: 47% (11 aa)

RHLSARRLLIKVHGVIKVTDFGL
| | ||  |.   .|.|| |||.
RDLAARNCLVGDQCVVKVSDFGM
Kinase AqueK336.AA Pkinase 19-34 45 7.879099 0.48 Pfam 139-158 (293) Show / Hide 
Range on Protein: 19-34
Range on HMM: 139-158/293
Sequence Identity: 45% (9 aa)

LLIKVHGVI----KVTDFGL
.||. .|.|    |..||||
ILIDNNGHIDACVKICDFGL