Gene AqueK330 (A.queenslandica)

AqueK330

Species: A.queenslandica
Alias: AqueK330
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK330.AA Protein None 385 None Fasta, JSON
AqueK330.kin_dom Protein Kinase Domain None 291 None Fasta, JSON

Protein domain

Protein domains of AqueK330.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TyrKc AqueK330.AA TyrKc 49-346 32 8.1e-100 338.83 SMART 1-280 (280) Show / Hide 
Range on Protein: 49-346
Range on HMM: 1-280/280
Sequence Identity: 32% (113 aa)

IKVTDYLGSGQFGTVNKGVWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGSGQFGTVNKGVWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAI
|.  . ||.|.||.| ||.|.                                                     . ||.|.|....    |  |..|| |
ITLGKKLGEGAFGEVYKGTWK-----------------------------------------------------IQVAVKMLKEDA----REDFMREARI

MGQF--HHPNVVKLHGVVTIG-------HPIMIVLELISGGDLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDE
| ..  ||||.|.|.||.| .       .|.|||.|. ..||||.|| | .|      |.  .. ||||| |||.|||||..|...||||||||.||...
MCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-----LC--MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGEN

GTGICKIADFGMSRDLQDE-------SYYISQ---SKK--IPIKWTAPEALHYKKYSSAS--------------EXHKPFEI-----DTNQECIRLVDSG
.  ..||.|||.|||. |.       .|| ..   ..|  .||.|.|||.. |.|....|                 .| .       .||| |..|..|
H--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG

YRLPPPPG--------CPKPMYKLMMQCWNPDTHNRPSFSDTSSSL
||.|.||         ||. ||..| |||. | ..||.||.  . .
YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK330.AA Pkinase_Tyr 103-287 43 3.7e-86 292.41 Pfam 8-195 (270) Show / Hide 
Range on Protein: 103-287
Range on HMM: 8-195/270
Sequence Identity: 43% (84 aa)

GSGQFGTVNKGVWT-TPTAGSVSVAIKTLNDNTSEDE--RVKFLQEAAIMGQF-HHPNVVKLHGVVT-IGHP--IMIVLELISGGDLKEYLNKFKPSPGE
|.|.||.| ||.|.  |  . . ||.|.|........  | .|..||.|| |. ||||.|.|.||.|  | |  |.||.|.  .|||..|| | .    |
GEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR----E

LVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESYY--ISQSKKIPIKWTAPEALHYKKYSSAS
   .  .. ||..|.|||.|||||..|...||||||||.||..  ....||.|||..||.....||   ... |.||||.|||...|.|....|
DKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS
Kinase AqueK330.AA TK 103-287 24 5.8e-76 253.96 In-house 8-375 (486) Show / Hide 
Range on Protein: 103-287
Range on HMM: 8-375/486
Sequence Identity: 24% (91 aa)

GSGQFG---TVNKGVWTT----------------------PTAGSVSVAIKTLN--DNTSEDERVK-----------FLQEAAIMGQFH-----HPNVVK
|.||||   .| || | .                      .. | . ||.|.|   |..|..|.             ||.||..| ...     |||.|.
GEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVR

LHGVVTIG------------HPIMIVLELISGGD----LKEYLNKFKPSPGELVLSSV------------------------------------------
|.||.| |            .|.|||.|. ..||    |..|| | .|   .   ..                                           
LYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKD

------PSILLS-------------------FCRQIASGMEYLSRK------KFVHRDLAARNILVSDEGT---------GICKIADFGMS--------R
       . ||.                   .|.|||.|||||..|      .||||||||||.||.....          .|||||||.|        |
HPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLAR

DL-QDESYYISQ------------------------SKKIPIKWTAPEALH---------YKKYSSAS
|. .|. || ..                        . |.||.|.|||.|          |.|....|
DIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKS
Kinase AqueK330.AA UTK 103-287 37 9.6e-70 237.76 In-house 8-221 (296) Show / Hide 
Range on Protein: 103-287
Range on HMM: 8-221/296
Sequence Identity: 37% (81 aa)

GSGQFGTVNKGVWTTPT--AGSVSVAIKTLN-DNTSEDERV---KFLQEAA---IMGQFH-HPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKPS
|.|.||.|.|. .|...  .. . ||.|... . ....|.    .|. ||.   .|.||| ||||..| ||.| . |.|||.|. ..|||  || . .|.
GQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPT

PGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEG-----TGICKIADFG---MSRDLQD--------ES-YYISQ-SKKIPIKWTA
|..  ..     .|.....||.||.||....||||||||||.|| . .       .|||||||   |||....        || || .|  ...||.|.|
PPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMA

PEALHYK-KYSSAS
|||| .  .....|
PEALTHHTRFTTKS
Kinase AqueK330.AA Eph 104-287 45 4.7e-66 220.83 In-house 9-191 (264) Show / Hide 
Range on Protein: 104-287
Range on HMM: 9-191/264
Sequence Identity: 45% (88 aa)

SGQFGTVNKGVWTTP-TAGSV---SVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKPSPGELVLS
.|.|| | .|   .|  .  |    |||||| .  .| .|. || ||.||||| |||...| |||| . |.||| |    | | ..| .     |...  
AGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHD---GQFTVI

SVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDES----YYISQSKKIPIKWTAPEALHYKKYSSAS
     |.   | ||||| |||   .||||||||||||. .   .||..|||.|| |.|..     | ... ||||.||||||. |.|..|||
Q----LVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSN--LVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSAS
Kinase AqueK330.AA Fer 103-287 37 1.6e-63 215.22 In-house 8-199 (283) Show / Hide 
Range on Protein: 103-287
Range on HMM: 8-199/283
Sequence Identity: 37% (74 aa)

GSGQFGTVNKG--VWTTPT-AGSV----SVAIKTLNDN-TSEDERVKFLQEAAIMGQ-FHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKPSP
|.| ||.| ||  . .     ..|     |. |... . ...... .|..|| || . . ||||||..|| .  .|||||.|...||.|..|| | |   
GEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYLKKNKNK-

GELVLSSVPSI--LLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGI-CKIADFGMSRDLQDESYYIS---QSKKIPIKWTAPEALHYKKYSSAS
       . |.  .. .| |.|.|||||  |. .|||.||||.|...... . |||.||||||.. |. |  .    ..|.||.|.|||.. .. ||...
-------TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKT
Kinase AqueK330.AA Src 103-284 41 5.4e-63 212.84 In-house 8-178 (255) Show / Hide 
Range on Protein: 103-284
Range on HMM: 8-178/255
Sequence Identity: 41% (76 aa)

GSGQFGTVNKGVWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKPSPGELVLSSVP
|.|||| | .|.|     |.. ||.|||   |   .   ||||| || .. |...|.|. |.. . || || |. | | | .|| | ..  ..| |    
GQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-DGEGRHLHL----

SILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQ--DESYYISQSKKIPIKWTAPEALHYKKYS
 .|...  |.|.||.||......||||||||.||...   .||.||||  | ..  |. |  ..  |.|||||||||..| ...
PQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN--VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFT
Kinase AqueK330.AA SFK-Src 103-284 44 3.5e-60 176.79 In-house 8-177 (259) Show / Hide 
Range on Protein: 103-284
Range on HMM: 8-177/259
Sequence Identity: 44% (83 aa)

GSGQFGTVNKGVWTTPTAGSVSVAIKTLND-NTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKPSPGELVLSSV
|||||| | ||.|   |.    ||.|||    .|..|   |||||..| .  ||| ..|. | |.| || |. ||.  | |  ||    |    | .   
GSGQFGDVWKGRWNNTTE----VAVKTLKPGAMSAEE---FLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHE--PHGRSLRM---

PSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESY-YISQSK-KIPIKWTAPEALHYKKYS
   |     |.|.|| ||  . ||||||||||.|| |    .||..|||||| | ...  |  .   | |||||||||  . ..|
-PQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDN--NVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFS
Kinase AqueK330.AA Ack 103-287 40 1e-55 186.4 In-house 8-192 (266) Show / Hide 
Range on Protein: 103-287
Range on HMM: 8-192/266
Sequence Identity: 40% (78 aa)

GSGQFGTVNKGVWTTPTAGSVSVAIKTLNDN--TSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPI-MIVLELISGGDLKEYLNKFKPSPGELVLS
|.| || | .|.||.|   ...||.| | .   ..  .   ||.|.||| .  ||..|.|.|||  . |  | | ||  .| | . | |  ...  . . 
GDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVV-LDQPMLMMVTELAPCGSLLDCLRK-HCRTAFFLI-

SVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILV-SDEGTGICKIADFGMSRDL-QDESYYISQSKK---IPIKWTAPEALHYKKYSSAS
   ..|. ||.|||.|| ||  | ..||||||||||. ||.     ||.||| .| | | | || .. ..   .|. | |||.| ... |.||
---HTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDD--RKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHAS
Kinase AqueK330.AA InsR 103-287 38 1.4e-52 174.88 In-house 8-202 (278) Show / Hide 
Range on Protein: 103-287
Range on HMM: 8-202/278
Sequence Identity: 38% (76 aa)

GSGQFGTVNKG--VWTTPTAGSV--SVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKPSPG--EL
| | ||.|  |      |  ..    .||||.|.| |  ||. ||.|| .| .| . .||.| ||.. | | ..| |.   |||| ||    |  .  ..
GQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRPEEEFNNP

VLS---SVPSI--LLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESYYISQSK-KIPIKWTAPEALHYKKYSSAS
..    .||.   ...   .|..|| ||  |||||||||.|| .|....|  .||.|||| ||. .  ||    | . |. | ||| |   .....|
GCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFT--VKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTTHS
Kinase AqueK330.AA TK-Unique 103-288 34 1.7e-52 179.29 In-house 8-221 (294) Show / Hide 
Range on Protein: 103-288
Range on HMM: 8-221/294
Sequence Identity: 34% (74 aa)

GSGQFGTVNKGVWTTPT--AGSV-SVAIKTLNDNTSEDERVKFLQEAAIMGQFH-HPNVVKLHGVVT-IGHPIMIVLELISGGDLKEYLNKFKPS-----
|.|.||.| .|  ....   .   .||.|.|.|| .. .. .||.|...| .   |||.|.. |. |  . | ||..| ...|.|  || ...|      
GEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQ

------------PGELVLSSVP-SILLSFCRQIASGMEYLSR--KKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESYYISQ-S-KKIPIKWTAP
            | .  ....    |..|. |||.|||||..  ||.|||||.|||.|...   ..|||.||||.||....  |... | ..|||.| ||
TYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE--DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAP

EALH--YKKY-SSASE
|.|   .. | .. |.
ESLKCYHGMYHTTKSD
Kinase AqueK330.AA FAK 103-287 38 8.9e-51 168.29 In-house 8-207 (285) Show / Hide 
Range on Protein: 103-287
Range on HMM: 8-207/285
Sequence Identity: 38% (80 aa)

GSGQFGTVNKGVWTTPTA------------------------GSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELIS
| |||| | .||.| .                            . |||||   ....|.. ||.||| || || || .||| |...  .|| |..||. 
GEGQFGDVYQGVYTNHKNGKGKNLAGNGKNSNSDQRNADSRPDKIQVAIKTCKKCCDDDNKEKFMQEAYIMKQFDHPHIVKLIGICEE-MPIWIIMELCK

GGDLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESYYISQ-SKKIPIKWTAPEA
 |.|. ||   |    .| . .    |. .| |..  | ||  ||||||| ||||.||| .     | .|||.|| ..|.||| .    | |||| .|| 
YGELRHYLQRNK---NSLKHAT----LILYCYQLCMAMAYLESKKFVHRDIAARNVLVSSPDC--VKLGDFGLSRWMHDHSYYKASPKGKLPIKWMSPES

LHYKKYSSAS
  .  . .||
INFRRFTTAS
Kinase AqueK330.AA S_TKc 96-347 21 3.1e-26 94.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 96-347
Range on HMM: 1-231/231
Sequence Identity: 21% (58 aa)

LQEAAIMGSGQFGTVNKGVWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISG--GDLKEYLNKFKPSP
 .   . |.| ||.| |....        |||| ..         ....| .|. . ||||.|||..|    . . .|.|...|  |||..|. | .. .
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

GELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESYYISQSKKIPIKWTAPEALHYKKYSS-AS-----
.  ...  .    ....||....||. .....||||   |||...      ||.|||..| |         .      . ||| |   .|.  ..     
LRFPFP--E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

--------EXHKPFEIDTNQECIRLVDSGYRLPPPPGCPKPMYKLMMQCWNPDTHNRPSFSDTSS--------SLS
            ||.  . |. ....            ....  ....|.. |  .||.  .              
GCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK330.AA Eph 297-346 44 6.7e-22 70.23 In-house 215-264 (264) Show / Hide 
Range on Protein: 297-346
Range on HMM: 215-264/264
Sequence Identity: 44% (22 aa)

TNQECIRLVDSGYRLPPPPGCPKPMYKLMMQCWNPDTHNRPSFSDTSSSL
.||. |  .. |||||||..||.....||..||  | ..|| |..  | |
SNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase AqueK330.AA Pkinase 96-267 25 5.1e-20 71.86 Pfam 1-168 (293) Show / Hide 
Range on Protein: 96-267
Range on HMM: 1-168/293
Sequence Identity: 25% (47 aa)

LQEAAIMGSGQFGTVNKGVWTTPTAGSVS-VAIKTLN-DNTSEDERVKFLQ--EAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGG----DLKEYLN
..   . ||| ||.| |...     |.   ||.|... .........  .   |..||  ..|||.|.|..... .  | .|.|.  ||    ||..|. 
YHIGRKIGSGSFGCVYKCHH----KGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

KFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGIC----KIADFGMSRDLQDESYYISQSKK
    . .  ..   .  . ....||..|.||. .....||||   |||..   .| .    ||.||| .. ..    | ..|  
T---WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD----Y-NNS-M
Kinase AqueK330.AA Pkinase_Tyr 297-346 41 5.6e-19 64.89 Pfam 220-270 (270) Show / Hide 
Range on Protein: 297-346
Range on HMM: 220-270/270
Sequence Identity: 41% (21 aa)

TNQECIRLV-DSGYRLPPPPGCPKPMYKLMMQCWNPDTHNRPSFSDTSSSL
.|.| .... ..|||.|.|..||...|.||.|||..|  .||.||.  . |
SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK330.AA Src 297-346 41 7.2e-17 53.79 In-house 205-255 (255) Show / Hide 
Range on Protein: 297-346
Range on HMM: 205-255/255
Sequence Identity: 41% (21 aa)

TNQECIRLVDSGYRLPPPPGCPKPMYK-LMMQCWNPDTHNRPSFSDTSSSL
||.| .. |. |||.| |..||. .|. .|.|||. |   || |    . |
TNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Pkinase_Tyr AqueK330.AA Pkinase_Tyr 49-102 36 1.5e-16 56.69 Pfam 1-57 (270) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-57/270
Sequence Identity: 36% (21 aa)

IKVTDYLGSGQFGTVNKGVWT-TPTAGSVSVAIKTLNDNTSEDE--RVKFLQEAAIM
|.    ||.|.||.| ||.|.  |  . . ||.|.|........  | .|..||.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIM
Kinase AqueK330.AA TK 292-346 23 2.8e-16 50.37 In-house 395-486 (486) Show / Hide 
Range on Protein: 292-346
Range on HMM: 395-486/486
Sequence Identity: 23% (22 aa)

PFEIDTN---------QECIRLVDSG--------------YRLPPPPGCP--------------KPMYKLMMQCWNPDTHNRPSFSDTSSSL
. .  .|         || .... .|              .|.|.||.||              . .| ||.|||..|   ||.||.  . |
YYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK330.AA Eph 49-103 42 5.3e-16 50.12 In-house 1-59 (264) Show / Hide 
Range on Protein: 49-103
Range on HMM: 1-59/264
Sequence Identity: 42% (25 aa)

IKVTDYLGSGQFGTVNKGVWTTP-TAGSV---SVAIKTLNDNTSEDERVKFLQEAAIMG
||..  .|.|.|| | .|   .|  .  |    |||||| .  .| .|. || ||.|||
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMG
Kinase AqueK330.AA UTK 297-346 38 1.2e-15 50.0 In-house 245-296 (296) Show / Hide 
Range on Protein: 297-346
Range on HMM: 245-296/296
Sequence Identity: 38% (20 aa)

TNQECIRLVDSG--YRLPPPPGCPKPMYKLMMQCWNPDTHNRPSFSDTSSSL
.|.. .  |  |  ||.|.|..|| |.|.||..||..|  .||.| |  . .
SNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK330.AA SFK-Src 291-339 43 2.3e-15 41.39 In-house 198-248 (259) Show / Hide 
Range on Protein: 291-339
Range on HMM: 198-248/259
Sequence Identity: 43% (22 aa)

KPFEIDTNQECIRLVDS--GYRLPPPPGCPKPMYKLMMQCWNPDTHNRPSF
.|..  ||.| .. ||   |||.| ||.||  .||.|..||     .|| |
IPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF
Kinase AqueK330.AA SFK-Src 49-102 47 1.2e-14 39.28 In-house 1-48 (259) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-48/259
Sequence Identity: 47% (26 aa)

IKVTDYLGSGQFGTVNKGVWTTPTAGSVSVAIKTLND-NTSEDERVKFLQEAAIM
|.    ||||||| | ||.|   |.    ||.|||    .|..|   |||||..|
IRLEKKLGSGQFGDVWKGRWNNTTE----VAVKTLKPGAMSAEE---FLQEAQVM
Kinase AqueK330.AA Ack 49-102 37 1.6e-14 45.4 In-house 1-56 (266) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-56/266
Sequence Identity: 37% (21 aa)

IKVTDYLGSGQFGTVNKGVWTTPTAGSVSVAIKTLNDN--TSEDERVKFLQEAAIM
|..   ||.| || | .|.||.|   ...||.| | .   ..  .   ||.|.|||
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIM
Kinase AqueK330.AA Ack 302-346 41 1.7e-13 41.94 In-house 221-266 (266) Show / Hide 
Range on Protein: 302-346
Range on HMM: 221-266/266
Sequence Identity: 41% (19 aa)

IRLVD-SGYRLPPPPGCPKPMYKLMMQCWNPDTHNRPSFSDTSSSL
....|  | ||| |. ||.  |..||||| ..   ||.||.    |
LQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase AqueK330.AA TK 49-102 26 1.7e-12 37.48 In-house 1-92 (486) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-92/486
Sequence Identity: 26% (24 aa)

IKVTDYLGSGQFG---TVNKGVWTT----------------------PTAGSVSVAIKTLN--DNTSEDERVK-----------FLQEAAIM
|.. . ||.||||   .| || | .                      .. | . ||.|.|   |..|..|.             ||.||..|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEM
Kinase AqueK330.AA TK-Unique 302-346 36 3.8e-12 38.28 In-house 249-294 (294) Show / Hide 
Range on Protein: 302-346
Range on HMM: 249-294/294
Sequence Identity: 36% (17 aa)

IRLVDSGYRLPPPPGC-PKPMYKLMMQCWNPDTHNRPSFSDTSSSL
....  |||.| |..| .. ||.|| .||. . . ||||..  . |
MECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK330.AA UTK 49-102 25 5.5e-12 37.29 In-house 1-63 (296) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-63/296
Sequence Identity: 25% (16 aa)

IKVTDYLGSGQFGTVNKGVWTTPT--AGSVSVAIKTLN-DNTSEDERV---KFLQEAA---IM
..  . ||.|.||.|.|. .|...  .. . ||.|... . ....|.    .|. ||.   .|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMM
Kinase AqueK330.AA FAK 291-351 37 1.1e-11 35.2 In-house 225-285 (285) Show / Hide 
Range on Protein: 291-351
Range on HMM: 225-285/285
Sequence Identity: 37% (23 aa)

KPFEIDTNQECIRLVDSGYRLPPPPGCPKPMYKLMMQCWNPDTHNRPSFSDTSSSLSSPDK
|||    |.. |  .  | ||| || ||  .| || .||  |   || | .   .|.   .
KPFQWVKNNDVIGRIENGERLPMPPNCPPTLYSLMTRCWAYDPSKRPRFKELKCQLKDIYQ
Kinase AqueK330.AA Fer 303-347 30 1.1e-11 36.21 In-house 238-283 (283) Show / Hide 
Range on Protein: 303-347
Range on HMM: 238-283/283
Sequence Identity: 30% (14 aa)

RLVDSGYRLPPPPGCPKPMYKLMM-QCWNPDTHNRPSFSDTSSSLS
. ...||..|.|...|......|| |||. |. .||....    | 
WIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK330.AA FAK 49-102 29 2.2e-11 34.25 In-house 1-78 (285) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-78/285
Sequence Identity: 29% (23 aa)

IKVTDYLGSGQFGTVNKGVWTTPTA------------------------GSVSVAIKTLNDNTSEDERVKFLQEAAIM
|.    .| |||| | .||.| .                            . |||||   ....|.. ||.||| ||
ITLNRCIGEGQFGDVYQGVYTNHKNGKGKNLAGNGKNSNSDQRNADSRPDKIQVAIKTCKKCCDDDNKEKFMQEAYIM
Kinase AqueK330.AA Src 49-102 46 2.9e-11 34.46 In-house 1-48 (255) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-48/255
Sequence Identity: 46% (25 aa)

IKVTDYLGSGQFGTVNKGVWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIM
||  . ||.|||| | .|.|     |.. ||.|||   |   .   ||||| ||
IKLCRKLGQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIM
Kinase AqueK330.AA TK-Unique 49-102 31 3.6e-11 34.89 In-house 1-57 (294) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-57/294
Sequence Identity: 31% (18 aa)

IKVTDYLGSGQFGTVNKGVWTTPT--AGSV-SVAIKTLNDNTSEDERVKFLQEAAIM
..| |..|.|.||.| .|  ....   .   .||.|.|.|| .. .. .||.|...|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMM
Kinase AqueK330.AA InsR 298-348 32 6.3e-11 32.84 In-house 227-278 (278) Show / Hide 
Range on Protein: 298-348
Range on HMM: 227-278/278
Sequence Identity: 32% (17 aa)

NQECIRLV-DSGYRLPPPPGCPKPMYKLMMQCWNPDTHNRPSFSDTSSSLSS
| .  . .   |  | || .||. ...|||.||      ||.| |  ..|  
NEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK330.AA InsR 49-102 37 6.7e-11 32.74 In-house 1-58 (278) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-58/278
Sequence Identity: 37% (22 aa)

IKVTDYLGSGQFGTVNKG--VWTTPTAGSV--SVAIKTLNDNTSEDERVKFLQEAAIM
|     .| | ||.|  |      |  ..    .||||.|.| |  ||. ||.|| .|
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVM
Kinase AqueK330.AA Fer 49-102 25 6.8e-10 29.99 In-house 1-62 (283) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-62/283
Sequence Identity: 25% (16 aa)

IKVTDYLGSGQFGTVNKG--VWTTPT-AGSV----SVAIKTLNDN-TSEDERVKFLQEAAIM
.. .. ||.| ||.| ||  . .     ..|     |. |... . ...... .|..|| ||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIM
Kinase AqueK330.AA Pkinase 49-68 35 0.394132 5.08 Pfam 1-20 (293) Show / Hide 
Range on Protein: 49-68
Range on HMM: 1-20/293
Sequence Identity: 35% (7 aa)

IKVTDYLGSGQFGTVNKGVW
...   .||| ||.| |...
YHIGRKIGSGSFGCVYKCHH