Gene AqueK304 (A.queenslandica)

AqueK304

Species: A.queenslandica
Alias: AqueK304
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK304.AA Protein None 296 None Fasta, JSON
AqueK304.kin_dom Protein Kinase Domain None 211 None Fasta, JSON

Protein domain

Protein domains of AqueK304.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK304.AA Pkinase_Tyr 82-296 40 1.4e-97 331.07 Pfam 1-221 (270) Show / Hide 
Range on Protein: 82-296
Range on HMM: 1-221/270
Sequence Identity: 40% (91 aa)

IKVLELLGSGYFATVNRAVWL-KPNLGEEEVAVKILSEKADNED--RIKFLQEAALMGQF-KHTNVLTLHGVVT-TDTS--VMIVTELMKNGDLHHWLLK
|. .. ||.| | .| ...|  .|  .. .||||.| |.|. |.  | .|..||..| |. .| |.. |.||.|  . .  ..||.|.|..|||.. | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

TKREGADLQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHDNICKISDFGMSHDLTKDEDYY-MAGEGGLIPVKWTAPESIKQHKYSSASDV
 . |. .  |..  ||..|.||. ||.||.|....| ||||||.|||..|..||.|||.. |.  ..|||  ...|| .|.||.|||.|.  |....|||
HR-EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

WSYGCVMYEIWSLGRKP-FDTLKN
||.| .|.|| ..|..| .  ..|
WSFGVLMWEIFTYGEQPTYPGMSN
Kinase AqueK304.AA TK 82-291 22 8.1e-89 297.82 In-house 1-395 (486) Show / Hide 
Range on Protein: 82-291
Range on HMM: 1-395/486
Sequence Identity: 22% (90 aa)

IKVLELLGSGYFA---TVNRAVWLKPN----------------------LGEEEVAVKILSEKADNEDRI-------------KFLQEAALMGQFK----
|.... ||.| |    .| .. |  .|                       |...||||.| |.......              .||.||. | ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HTNVLTLHGVVTTDTS------------VMIVTELMKNGD----LHHWLLKTKREGADLQ---------------------------------------
 | |.. |.||.| . .            .|||.|.|..||    |...| | .... . |                                       
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------TTPGVLLNFCRQICLGMAYLSSR------QFVHCDLAARNILVTHDNI-----------CKISDFGMS-
                                |.  || .|.||. ||.||.|.      .||| ||||||.||...|.           |||.|||.| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------HDLTKDEDYYMAGE-----------------------GGLIPVKWTAPESIKQHK---------YSSASDVWSYGCVMYEIWSLGRKPF
        |. .|.||| ...                       || .|..|.|||... ..         ....|||||.|..|.||...|..|.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPY
Kinase AqueK304.AA UTK 82-291 36 6.3e-80 271.84 In-house 1-241 (296) Show / Hide 
Range on Protein: 82-291
Range on HMM: 1-241/296
Sequence Identity: 36% (88 aa)

IKVLELLGSGYFATVNRAVWLKPN--LGEEEVAVKILSEKAD-NEDRI---KFLQEAA---LMGQFK-HTNVLTLHGVVTTDTSVMIVTELMKNGDLHHW
.. ...||.| | .|..| . ...   .|  |||| ....|| . ..    .|. ||.   .|.||. | ||| | ||.| .   |||||.|.|||| . 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LLKTKR--EGADLQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHD-------NICKISDFG---MSHDLTK--------DEDYYMAGEGGL
| . ..  ...... |   .| ....|  ||.||.|..|||.||||||.||...       ..|||.|||   ||...          . .|||| . . 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

IPVKWTAPESIKQH-KYSSASDVWSYGCVMYEIWSLGRKPF
.|..|.|||.. .| .....|||||.| |..|||. ||.|.
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPY
Kinase AqueK304.AA TyrKc 82-294 29 5.9e-71 242.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 82-294
Range on HMM: 1-280/280
Sequence Identity: 29% (88 aa)

IKVLELLGSGYFATVNRAVWLKPNLGEEEVAVKILSEKADNEDRIKFLQEAALMGQF--KHTNVLTLHGVVTTD-------TSVMIVTELMKNGDLHHWL
|. .. ||.| | .| ...|       ..|||| | | |    |  |..|| .| ..  .| |.. |.||.|..         .|||.|.|..|||.. |
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

LKTKREGADLQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHDNICKISDFGMSHDLTKD------EDYYMAGE--GGL--IPVKWTAPESI
 |....      ..  ||.|| ||. ||.||.|....| ||||||.||......||||||.| |.. |      .|||.. |  ||   .|..|.|||.|
RKHRPK-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

KQHKYSSASDVWSYGCVMYEIWSLGRKPFDT---------------------------------------------------------------L
. .|....|||||.| .|.|| ..| .|                                                                  .
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK304.AA Eph 82-291 45 8.1e-71 237.09 In-house 1-211 (264) Show / Hide 
Range on Protein: 82-291
Range on HMM: 1-211/264
Sequence Identity: 45% (98 aa)

IKVLELLGSGYFATVNRAVWLKP-NLGEE---EVAVKILSEKADNEDRIKFLQEAALMGQFKHTNVLTLHGVVTTDTSVMIVTELMKNGDLHHWLLKTKR
||. . .|.| |  | .    .|    |     ||.| | . .   .|. || ||..|||| | |.. | ||||    |||||| | || |  .|   ..
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFL--RQH

EGADLQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHDNICKISDFGMSHDLTKD---EDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVW
.|   | |.. |.   | |  || |||.  .|| |||||||||  . .||.||||.|  | .|   |. |    || ||..||||| |   |..||||||
DG---QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVW

SYGCVMYEIWSLGRKPF
||| || |. | | .|.
SYGIVMWEVMSYGERPY
Kinase AqueK304.AA Src 82-290 40 4.6e-67 226.86 In-house 1-200 (255) Show / Hide 
Range on Protein: 82-290
Range on HMM: 1-200/255
Sequence Identity: 40% (84 aa)

IKVLELLGSGYFATVNRAVWLKPNLGEEEVAVKILSEKADNEDRIKFLQEAALMGQFKHTNVLTLHGVVTTDTSVMIVTELMKNGDLHHWLLKTKREGAD
|| .. ||.|.|  |  ..|     |. .|||| |...    .   ||||| .| ...| ... |. |....  . ||||.|..| |  .| | ..||  
IKLCRKLGQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-DGEGRH

LQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHDNICKISDFGMSHDLTK-DEDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVM
|. .   |. .  |.  |||||.|....| ||||||.|| ..|.||. |||    |.| |.| | | .|  .|.|||||| |  ....  |||||.|  .
LHLPQ--LIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILL

YEIWSLGRKP
.|| . || |
TEIVTYGRVP
Kinase AqueK304.AA TK-Unique 82-291 33 9e-67 228.14 In-house 1-240 (294) Show / Hide 
Range on Protein: 82-291
Range on HMM: 1-240/294
Sequence Identity: 33% (81 aa)

IKVLELLGSGYFATVNRAVWLKPN--LGEE-EVAVKILSEKADNEDRIKFLQEAALMGQFK-HTNVLTLHGVVTTDT-SVMIVTELMKNGDLHHWLLKTK
..|....|.| | .| |.   ...   ..   |||| | ..|. .|. .||.|...| . . | |.... |. |... ..||. | . .|.| | | ...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

RE-----------------GADLQTT---PGVLLNFCRQICLGMAYLSS--RQFVHCDLAARNILVTHDNICKISDFGMSHDLTKDEDYYMAGEGGLIPV
..                  .. .|.   |. |..|. ||. ||.||.|  ...|| ||.|||.|.|.|..|||.||||. |. ....| | .. | ||.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWTAPESIK--QHKY-SSASDVWSYGCVMYEIWSLGRKPF
.| ||||.|  .. | .. |||||.|..|.|| .||  |.
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPY
Kinase AqueK304.AA SFK-Src 82-296 40 1.6e-66 195.95 In-house 1-205 (259) Show / Hide 
Range on Protein: 82-296
Range on HMM: 1-205/259
Sequence Identity: 40% (88 aa)

IKVLELLGSGYFATVNRAVWLKPNLGEEEVAVKILSEKADNEDRIKFLQEAALMGQFKHTNVLTLHGVVTTDTSVMIVTELMKNGDLHHWLLKTKREGAD
|.  . |||| |  | . .| .      ||||| |   |  ..   |||||..| . .|.|   |. | |    . |.|||||.| |  .|   . ..  
IRLEKKLGSGQFGDVWKGRWNN----TTEVAVKTLKPGAMSAE--EFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLR

LQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHDNICKISDFGMSHDLTKDEDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMY
...    |     |.  |||||    ||| ||||||.||   |.||. |||||  | .|.  | | ||   |.||||||  .  ..|  |||||.|  |.
MPQ----LVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMM

EIWSLGRKPFDTLKN
||  .||.|.. . |
EIVTYGRIPYPGMTN
Kinase AqueK304.AA Ack 82-291 37 2.5e-62 209.08 In-house 1-212 (266) Show / Hide 
Range on Protein: 82-291
Range on HMM: 1-212/266
Sequence Identity: 37% (80 aa)

IKVLELLGSGYFATVNRAVWLKPNLGEEEVAVKILSEKADNED--RIKFLQEAALMGQFKHTNVLTLHGVVTTDTSVMIVTELMKNGDLHHWLLKTKREG
|...|.||.| |. | |..|  |.    .||||.|.    . .     ||.|.| | .  | ... |.||| .  ..| ||||   | |.  | |     
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRK-HCRT

ADLQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHD-NICKISDFGMSHDLTKDEDYYMAGEGG--LIPVKWTAPESIKQHKYSSASDVWSY
| .  .  .|..||.||. ||.|| .. ..| ||||||||.  | .  ||.||| .  |   ||||  ..     .|  | |||.... . |.|||||..
AFFLIH--TLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMF

GCVMYEIWSLGRKPF
|  . |  | |..|.
GVTLWEMFSYGEEPW
Kinase AqueK304.AA InsR 82-290 35 1.7e-60 201.84 In-house 1-221 (278) Show / Hide 
Range on Protein: 82-290
Range on HMM: 1-221/278
Sequence Identity: 35% (79 aa)

IKVLELLGSGYFATVNRA--VWLKPNLGEE--EVAVKILSEKADNEDRIKFLQEAALMGQFKHTNVLTLHGVVTTDTSVMIVTELMKNGDLHHWLLKTKR
|  .  .| | | .|       . |. ..   ..|.|.. |.|  ..|| ||.||  | .|.. .|  | ||...    ..| |.|. |||  .|.  .|
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLR-SRR

EGAD-----LQ-----TTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHDNICKISDFGMSHDLTKDEDYYMAGEGGLIPVKWTAPESIKQHKY
. .      ..      ... ...   .|| ||||| .. ||| |||.|| .| ||  .|| ||||  |.  . |||  | .|. || | ||||.|  ..
PEEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIY-EHDYYRKGGKGMLPVRWMAPESLKDGVF

SSASDVWSYGCVMYEIWSLGRKP
...|||||.| |..|. .||  |
TTHSDVWSFGVVLWEMVTLGEQP
Kinase AqueK304.AA Fer 82-291 31 1.3e-57 194.74 In-house 1-219 (283) Show / Hide 
Range on Protein: 82-291
Range on HMM: 1-219/283
Sequence Identity: 31% (70 aa)

IKVLELLGSGYFATVNRA----VWLKPNLGEE---EVAVKIL-SEKADNEDRIKFLQEAALMGQ-FKHTNVLTLHGVVTTDTSVMIVTELMKNGDLHHWL
..  . ||.| | .| ..      .|.   .    .|.|| . .|.|. | ...|..|| .| . ..| ||  ..|| . .  .||| |....|.|   |
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

LKTKREGADLQTTPG-VLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTH-DNICK--ISDFGMSHDLTKDEDYYMAG-EGGLIPVKWTAPESIKQHKY
 |.| .     | .   ....| |.. ||.|| |.. .| |.||||.|... .. .|  ||||||| ......  |  . .   .|..|.|||...   |
KKNKNK-----TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIY

SSASDVWSYGCVMYEIWSLGRKPF
|...||||.|....|| . | .|.
SPKTDVWSFGVMCWEIFTNGAEPY
Kinase AqueK304.AA Frk 82-296 38 2.9e-56 193.22 In-house 1-208 (260) Show / Hide 
Range on Protein: 82-296
Range on HMM: 1-208/260
Sequence Identity: 38% (84 aa)

IKVLELLGSGYFATVNRAVWLKPNLGEEEVAVKILSEKADNEDRIKFLQEAALMGQFKHTNVLTLHGVVTTDTSVMIVTELMKNGDLHHWLLKTKREGAD
|...  |||| |  |    |      .  |||| |  |.   |   ||.|| .| . .|. .. |. | | .  ..|.||||..| | ..|   ...|  
IQLIRRLGSGQFGEVWEGLWNN----TTPVAVKTL--KPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQ

LQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHDNICKISDFGMSHDLTKDED-YYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVM
.| .   |..   |.  ||||| |. ..| ||||||.||  .||||| |||.   | ||.   | .  |  .|.|||||| .. .|..  |||||.| ..
CQMQ--QLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILL

YEIWSLGRKPFDTLKN
.||   || |.  . |
TEIITYGRMPYPGMTN
Kinase AqueK304.AA Pkinase 82-282 24 7.7e-35 124.27 Pfam 1-204 (293) Show / Hide 
Range on Protein: 82-282
Range on HMM: 1-204/293
Sequence Identity: 24% (52 aa)

IKVLELLGSGYFATVNRAVWLKPNLGEEEVAVKILSEKADNE--DRIKFL-QEAALMGQFKHTNVLTLHGVVTTDTSVMIVTELMKNG----DLHHWLLK
..... .||| |..| .... . .    .|||||.. . ...  |..... .|...|  ..| |...|.......... .|.|.. .|    ||....  
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

TKREGADLQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHDNIC----KISDFGMSHDL-TKDEDYYMAGEGGLIPVKWTAPESIK-QHKYS
 .|.|. .  .. .. ....||. |..|. |. ..|.||   |||. ... .    ||.||| .  . .     ..   | .    . ||| |. . .|.
-WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTP---WYMAPEVIRGGQYYG

SASDVWSYGCVMYE
...|.||.||..||
PKVDMWSCGCILYE
Kinase AqueK304.AA S_TKc 82-296 21 2.9e-26 94.48 SMART 1-220 (231) Show / Hide 
Range on Protein: 82-296
Range on HMM: 1-220/231
Sequence Identity: 21% (54 aa)

IKVLELLGSGYFATVNRAVWLKPNLGEEEVAVKILSEKADNEDRIKFLQEAALMGQFKHTNVLTLHGVVTTDTSVMIVTELMKN--GDLHHWLLKTKREG
 ..|...|.| |..| .... |     ..||.||..        .....| ... . .| |. .|..|  . ... .|.|.. .  |||.. . | .|.|
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

ADLQTTPGVLLNFCRQICLGMAYLSSRQFVHCDLAARNILVTHDNICKISDFGMSHDLTKDEDYYMAGEGGLIPVKWTAPESIKQHKYSS-ASDVWSYGC
 . . .. .   ...|||....|. |....|.||   |||...    ||.|||..  |                  . ||| .   .|.  ..|.|| ||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

VMYEIWSLGRKPFD--------------------------------TLKN
..||  . |. ||.                                 . .
ILYEMLC-GYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ