Gene AqueK296 (A.queenslandica)

AqueK296

Species: A.queenslandica
Alias: AqueK296
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK296.AA Protein None 172 None Fasta, JSON
AqueK296.kin_dom Protein Kinase Domain None 132 None Fasta, JSON

Protein domain

Protein domains of AqueK296.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK296.AA Pkinase_Tyr 19-133 44 3.4e-59 201.09 Pfam 152-270 (270) Show / Hide 
Range on Protein: 19-133
Range on HMM: 152-270/270
Sequence Identity: 44% (53 aa)

IADFGMSRDL-KDESY-YISQAKKIPIKWTAPEALHYKKYSSASDVWSYGALMYEIWSLGHKP-FENSTNQECIRLV-DSGYRLPPPPGCPKPMYKLMMQ
|.|||..||. .|. | . ..  |.||||.|||...|.|....|||||.| ||.|| ..| .| ... .|.| .... ..|||.|.|..||...|.||.|
ICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQ

CWNPDTHDRPSFSDISSSL
||..|  |||.||.| . |
CWHYDPEDRPTFSEIHEQL
Kinase AqueK296.AA Eph 19-133 47 8.5e-57 189.27 In-house 146-264 (264) Show / Hide 
Range on Protein: 19-133
Range on HMM: 146-264/264
Sequence Identity: 47% (57 aa)

IADFGMSRDLKDES----YYISQAKKIPIKWTAPEALHYKKYSSASDVWSYGALMYEIWSLGHKPFENSTNQECIRLVDSGYRLPPPPGCPKPMYKLMMQ
..|||.|| |.|..     | ..  ||||.||||||. |.|..||||||||| .| |. | | .|. . .||. |  .. |||||||..||.....||..
VSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLD

CWNPDTHDRPSFSDISSSL
||  | ..|| |..| | |
CWQKDRNHRPHFQQIVSIL
Kinase AqueK296.AA TK 19-133 28 1.1e-53 177.92 In-house 292-486 (486) Show / Hide 
Range on Protein: 19-133
Range on HMM: 292-486/486
Sequence Identity: 28% (56 aa)

IADFGMS--------RDL-KDESYYISQ------------------------AKKIPIKWTAPEALH---------YKKYSSASDVWSYGALMYEIWSLG
|||||.|        ||. .|. || ..                          |.||.|.|||.|          |.|....|||||.| ||.||...|
IADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYG

HKPFEN-STN---------QECIRLVDSG--------------YRLPPPPGCP--------------KPMYKLMMQCWNPDTHDRPSFSDISSSL
 .|.    .|         || .... .|              .|.|.||.||              . .| ||.|||..|  |||.||.. . |
QEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK296.AA UTK 19-133 39 1.9e-49 167.33 In-house 166-296 (296) Show / Hide 
Range on Protein: 19-133
Range on HMM: 166-296/296
Sequence Identity: 39% (52 aa)

IADFG---MSRDLKD--------ES-YYISQ-AKKIPIKWTAPEALHYK-KYSSASDVWSYGALMYEIWSLGHKPFENSTNQECIRLVDSG--YRLPPPP
|||||   |||....        || || .| ....||.|.||||| .  .....|||||.| ...|||. | .|... .|.. .  |  |  ||.|.|.
IADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPW

GCPKPMYKLMMQCWNPDTHDRPSFSDISSSL
.|| |.|.||..||..|  .||.| |. . .
DCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK296.AA SFK-Src 19-126 47 2.7e-49 143.89 In-house 137-248 (259) Show / Hide 
Range on Protein: 19-126
Range on HMM: 137-248/259
Sequence Identity: 47% (53 aa)

IADFGMSRDLKDESY-YIS-QAKKIPIKWTAPEALHYKKYSSASDVWSYGALMYEIWSLGHKPFENSTNQECIRLVDS--GYRLPPPPGCPKPMYKLMMQ
..|||||| | ...  |   .  | |||||||||  . ..|  |||||.| ||.||  .| .|..  ||.| .. ||   |||.| ||.||  .||.|..
VGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFD

CWNPDTHDRPSF
||     ||| |
CWQHEPDDRPTF
Kinase AqueK296.AA Src 19-133 43 3.8e-49 165.08 In-house 138-255 (255) Show / Hide 
Range on Protein: 19-133
Range on HMM: 138-255/255
Sequence Identity: 43% (51 aa)

IADFGMSRDLK--DESYYISQAKKIPIKWTAPEALHYKKYSSASDVWSYGALMYEIWSLGHKPFENSTNQECIRLVDSGYRLPPPPGCPKPMYK-LMMQC
.||||  | .|  |. |  ..  |.|||||||||..| ...  |||||.| |..|| . |  | .  ||.| .. |. |||.| |..||. .|. .|.||
VADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQC

WNPDTHDRPSFSDISSSL
|. |  .|| |  . . |
WHKDPEQRPTFEYLQWFL
Kinase AqueK296.AA SRM 19-134 44 5.1e-47 155.22 In-house 138-253 (253) Show / Hide 
Range on Protein: 19-134
Range on HMM: 138-253/253
Sequence Identity: 44% (52 aa)

IADFGMSRDLKDESYYISQAKKIPIKWTAPEALHYKKYSSASDVWSYGALMYEIWSLGHKPFENSTNQECIRLVDSGYRLPPPPGCPKPMYKLMMQCWNP
..|||. | .||  |  |   .||.|||||||. |  ||  |||||.| |..|. . |  |..  || | .  .| |||.| |  ||   .|||..||  
VGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCR

DTHDRPSFSDISSSLS
|  .||.| |    |.
DPEQRPCFKDLREKLT
Kinase AqueK296.AA Fer 19-134 35 1.4e-45 153.27 In-house 155-283 (283) Show / Hide 
Range on Protein: 19-134
Range on HMM: 155-283/283
Sequence Identity: 35% (46 aa)

IADFGMSRDLKDESYYIS---QAKKIPIKWTAPEALHYKKYSSASDVWSYGALMYEIWSLGHKPFEN------STNQ--ECIRL-VDSGYRLPPPPGCPK
|.||||||...|. |  .    |.|.||.|.|||.. .. ||...||||.| ...|| . | .|...       ||.  ....  ...||..|.|...|.
ISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPP

PMYKLMM-QCWNPDTHDRPSFSDISSSLS
.....|| |||. |. |||....|   | 
EIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK296.AA Syk 19-127 45 2.4e-42 143.55 In-house 147-257 (257) Show / Hide 
Range on Protein: 19-127
Range on HMM: 147-257/257
Sequence Identity: 45% (50 aa)

IADFGMSRDLK-DESYYISQAK-KIPIKWTAPEALHYKKYSSASDVWSYGALMYEIWSLGHKPFENSTNQECIRLVDSGYRLPPPPGCPKPMYKLMMQCW
| |||||. |  |..|| ..   | |.|| |||   | | |..|||||.| .| |  |.| ||    ..|| . ....| |.. |.|||. || || .||
ISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNCPNGCPQEMYQLMNKCW

NPDTHDRPSFS
  .  ||| |.
IYKWCDRPTFV
Kinase AqueK296.AA TK-Unique 19-133 39 6e-42 142.45 In-house 174-294 (294) Show / Hide 
Range on Protein: 19-133
Range on HMM: 174-294/294
Sequence Identity: 39% (48 aa)

IADFGMSRDLKDESYYISQAK--KIPIKWTAPEALH--YKKY-SSASDVWSYGALMYEIWSLGHKPFENSTNQECIRLVDSGYRLPPPPGC-PKPMYKLM
|.||||.||. ..  |... .  .|||.| |||.|   .. | .. |||||.| ||.|| .||  |. .  . . ....  |||.| |..| .. ||.||
ICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLM

MQCWNPDTHDRPSFSDISSSL
 .||. . ..||||..| . |
KSCWQWEPEERPSFRQIKHRL
Kinase AqueK296.AA Tec 19-135 40 1.2e-41 143.33 In-house 138-254 (254) Show / Hide 
Range on Protein: 19-135
Range on HMM: 138-254/254
Sequence Identity: 40% (47 aa)

IADFGMSRDLKDESYYISQAKKIPIKWTAPEALHYKKYSSASDVWSYGALMYEIWSLGHKPFENSTNQECIRLVDSGYRLPPPPGCPKPMYKLMMQCWNP
..||||.|   |  |  |   | |.|| .|| .|| .||| ||||..| || |..|.|  |.|| .| | .  |  |.||  |  |.. .|. | .||  
VSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHE

DTHDRPSFSDISSSLSS
   .||.|..  ...  
KPEERPTFQQLLRQITE
TyrKc AqueK296.AA TyrKc 1-133 22 7.2e-15 17.7 SMART 16-280 (280) Show / Hide 
Range on Protein: 1-133
Range on HMM: 16-280/280
Sequence Identity: 22% (60 aa)

MQGK----------------------RLVLTIG---------LYIVWSQ---------------------------------------------------
..|.                      |.   .|         . .. .|                                                   
YKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEY

-------------------------IADFGMSRDLKDE-------SYYISQ---AKK--IPIKWTAPEALHYKKYSSASDVWSYGALMYEIWSLGHKPFE
                         |.|||.|||..|.       .|| ..    .|  .||.|.|||.. |.|....|||||.| .|.|| ..| .| .
LHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYP

N-----STNQECIRLVDSGYRLPPPPG--------CPKPMYKLMMQCWNPDTHDRPSFSDISSSL
.      .||| |..|..|||.|.||         ||. ||..| |||. | .|||.||.| . .
GMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK296.AA Pkinase 19-133 17 1.8e-10 38.08 Pfam 153-293 (293) Show / Hide 
Range on Protein: 19-133
Range on HMM: 153-293/293
Sequence Identity: 17% (26 aa)

IADFGMSRDLKDESYYISQAKKIP---IKWTAPEALH-YKKYSSASDVWSYGALMYEIWSLGHKPFENS------TNQECIRLVDS-GYRLPPPPGCP--
|.||| .. ..   |  ..  . .   . . ||| .  ...|....|.||.| ..||  . |. || ..      . ...|... .  .. . |  |.  
ICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSIS

-----------------KPMYKLMMQCWNPDTHDRPSFSDISSS--L
                 ... ...  |...| ..||.. .|  .  .
YFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF